TY  - JOUR
AU  - Marković, Violeta
AU  - Erić, Slavica
AU  - Juranić, Zorica
AU  - Stanojković, Tatjana
AU  - Joksović, Ljubinka
AU  - Ranković, Branislav
AU  - Kosanić, Marijana
AU  - Joksović, Milan D.
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1500
AB  - A series of aminomethylidene derivatives obtained from 4-formyledaravone were synthesized and characterized by IR, NMR and elemental analysis. All the compounds were screened for their antitumor activity. The compound containing 5-phenylpyrazole moiety (3q) exhibited remarkable antitumor activity in in vitro assays, especially against human breast cancer MDA-MB-361 and MDA-MB-453 cell lines. The most important whole-molecule descriptors for antitumor activity on MDA-MB-453 cells belong to the group of quantum-chemical descriptors.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Bioorganic Chemistry
T1  - Synthesis, antitumor activity and QSAR studies of some 4-aminomethylidene derivatives of edaravone
VL  - 39
IS  - 1-3
SP  - 18
EP  - 27
DO  - 10.1016/j.bioorg.2010.10.003
ER  - 

@article{
author = "Marković, Violeta and Erić, Slavica and Juranić, Zorica and Stanojković, Tatjana and Joksović, Ljubinka and Ranković, Branislav and Kosanić, Marijana and Joksović, Milan D.",
year = "2011",
abstract = "A series of aminomethylidene derivatives obtained from 4-formyledaravone were synthesized and characterized by IR, NMR and elemental analysis. All the compounds were screened for their antitumor activity. The compound containing 5-phenylpyrazole moiety (3q) exhibited remarkable antitumor activity in in vitro assays, especially against human breast cancer MDA-MB-361 and MDA-MB-453 cell lines. The most important whole-molecule descriptors for antitumor activity on MDA-MB-453 cells belong to the group of quantum-chemical descriptors.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Bioorganic Chemistry",
title = "Synthesis, antitumor activity and QSAR studies of some 4-aminomethylidene derivatives of edaravone",
volume = "39",
number = "1-3",
pages = "18-27",
doi = "10.1016/j.bioorg.2010.10.003"
}

Marković, V., Erić, S., Juranić, Z., Stanojković, T., Joksović, L., Ranković, B., Kosanić, M.,& Joksović, M. D.. (2011). Synthesis, antitumor activity and QSAR studies of some 4-aminomethylidene derivatives of edaravone. in Bioorganic Chemistry
Academic Press Inc Elsevier Science, San Diego., 39(1-3), 18-27.
https://doi.org/10.1016/j.bioorg.2010.10.003

Marković V, Erić S, Juranić Z, Stanojković T, Joksović L, Ranković B, Kosanić M, Joksović MD. Synthesis, antitumor activity and QSAR studies of some 4-aminomethylidene derivatives of edaravone. in Bioorganic Chemistry. 2011;39(1-3):18-27.
doi:10.1016/j.bioorg.2010.10.003 .

Marković, Violeta, Erić, Slavica, Juranić, Zorica, Stanojković, Tatjana, Joksović, Ljubinka, Ranković, Branislav, Kosanić, Marijana, Joksović, Milan D., "Synthesis, antitumor activity and QSAR studies of some 4-aminomethylidene derivatives of edaravone" in Bioorganic Chemistry, 39, no. 1-3 (2011):18-27,
https://doi.org/10.1016/j.bioorg.2010.10.003 . .