TY  - JOUR
AU  - Pešić, Deniel
AU  - Đukić, Mirjana
AU  - Stanojević, Ivan
AU  - Živković, Vladimir
AU  - Bolevich, Sergey
AU  - Bolevich, Stefani
AU  - Jakovljević, Vladimir
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5559
AB  - Background: The influence of homeostatically regulated physiological processes, including cardiorespiratory fitness (VO2max), on the response to physical stressors such as acclimatisation and marching, remains understudied. We aimed to investigate the effects of summer and winter acclimatisation and marching on cortisol levels and blood lactate, to gain insight into the role of these physiological processes in the stress response. Methods: Two groups of young Europeans, classified as poor (PCF; n=9) and good physical condition (GCF; n=21), based on a VO2max threshold of 40 mL O2/ kg/min, underwent 2-h march (6–7 km/h) in winter (5 ∘C) and summer (32 ∘C). Commercial tests, UniCel DxI Access Cortisol assay and EKF Biosen Clinic/GP assay were used for cortisol and lactate blood measurements (morning samples and those taken immediately after marches), respectively. Results: Basal cortisol levels were significantly higher at 5 °C than at 32 °C (PCF group: P=0.0079; cortisol dropped after the march at 5 °C in both groups, but increased at 32 °C only in PCF. Basal lactate levels were higher at 32 °C only in the GCF group (compared to PCF, P=0.0014) and post-marching (compared to basal values, P=0.0002). Conclusion: Cold exposure elicits a more significant stress response, based on higher basal cortisol levels, in individuals with worse physical fitness. Anaerobe metabolism prevails in participants with better physical fitness exposed to high ambient temperature based on increased basal and post-marching lactate levels. The study is significant for individual training/performance optimisation as it indicates the association between physiological stress responses and individual physical fitness levels.
AB  - Uvod: Uticaj homeostatski regulisanih fiziolo{kih procesa, uklju~uju}i kardiorespiratornu kondiciju (VO2max), na odgovor na fizi~ke stresore poput aklimatizacije i mar{i- ranja, ostaje nedovoljno prou~en. Cilj istra`ivanja je bio i da se ispita uticaj aklimatizacije i mar{iranja tokom leta i zime na nivoe kortizola i laktoze u krvi, pru`aju}i uvid u ulogu ovih fiziolo{kih procesa u odgovoru na stres. Metode: Dve grupe mladih Evropljana, klasifikovane kao osobe sa slabom (PCF; n=9) i dobrom fizi~kom kondicijom (GCF; n=21), na osnovu praga VO2max od 40 mL O 2/kg/min, su bile izlo`ene dvosatnom mar{u (6–7 km/h) u dva navrata, zimi na 5 °C i leti, na 32 °C. U uzorcima krvi (jutarnji i neposredno nakon mar{a) su odre|ivani nivoi kortizola i laktata komercijalnim testovima, UniCel DxI Access Cortisol i EKF Biosen Clinic/GP. Rezultati: Bazalni nivoi kortizola su bili zna~ajno vi{i na 5 °C nego na 32 °C (u PCF grupi: P=0,0079); nakon mar{i- ranja na 5 °C kortizol opada u obe grupe a pove}an je na 32 °C samo u PCF grupi. Bazalni nivoi laktoze bili su vi{i na 32 °C samo u GCF grupi (porede}i sa PCF grupom, P=0,0014) i nakon mar{iranja (porede}i sa bazalnim vred- nostima, P=0,0002).
PB  - Society of Medical Biochemists of Serbia
T2  - Journal of Medical Biochemistry
T1  - Cardiorespiratory fitness mediates cortisol and lactate responses to winter and summer marches
T1  - Kardiorespiratorni fitnes i njegov značaj u reakcijama kortizola i laktata prilikom zimskih i letnjih marševa
VL  - 43
IS  - 1
SP  - 72
EP  - 85
DO  - 10.5937/jomb0-44369
ER  - 

@article{
author = "Pešić, Deniel and Đukić, Mirjana and Stanojević, Ivan and Živković, Vladimir and Bolevich, Sergey and Bolevich, Stefani and Jakovljević, Vladimir",
year = "2024",
abstract = "Background: The influence of homeostatically regulated physiological processes, including cardiorespiratory fitness (VO2max), on the response to physical stressors such as acclimatisation and marching, remains understudied. We aimed to investigate the effects of summer and winter acclimatisation and marching on cortisol levels and blood lactate, to gain insight into the role of these physiological processes in the stress response. Methods: Two groups of young Europeans, classified as poor (PCF; n=9) and good physical condition (GCF; n=21), based on a VO2max threshold of 40 mL O2/ kg/min, underwent 2-h march (6–7 km/h) in winter (5 ∘C) and summer (32 ∘C). Commercial tests, UniCel DxI Access Cortisol assay and EKF Biosen Clinic/GP assay were used for cortisol and lactate blood measurements (morning samples and those taken immediately after marches), respectively. Results: Basal cortisol levels were significantly higher at 5 °C than at 32 °C (PCF group: P=0.0079; cortisol dropped after the march at 5 °C in both groups, but increased at 32 °C only in PCF. Basal lactate levels were higher at 32 °C only in the GCF group (compared to PCF, P=0.0014) and post-marching (compared to basal values, P=0.0002). Conclusion: Cold exposure elicits a more significant stress response, based on higher basal cortisol levels, in individuals with worse physical fitness. Anaerobe metabolism prevails in participants with better physical fitness exposed to high ambient temperature based on increased basal and post-marching lactate levels. The study is significant for individual training/performance optimisation as it indicates the association between physiological stress responses and individual physical fitness levels., Uvod: Uticaj homeostatski regulisanih fiziolo{kih procesa, uklju~uju}i kardiorespiratornu kondiciju (VO2max), na odgovor na fizi~ke stresore poput aklimatizacije i mar{i- ranja, ostaje nedovoljno prou~en. Cilj istra`ivanja je bio i da se ispita uticaj aklimatizacije i mar{iranja tokom leta i zime na nivoe kortizola i laktoze u krvi, pru`aju}i uvid u ulogu ovih fiziolo{kih procesa u odgovoru na stres. Metode: Dve grupe mladih Evropljana, klasifikovane kao osobe sa slabom (PCF; n=9) i dobrom fizi~kom kondicijom (GCF; n=21), na osnovu praga VO2max od 40 mL O 2/kg/min, su bile izlo`ene dvosatnom mar{u (6–7 km/h) u dva navrata, zimi na 5 °C i leti, na 32 °C. U uzorcima krvi (jutarnji i neposredno nakon mar{a) su odre|ivani nivoi kortizola i laktata komercijalnim testovima, UniCel DxI Access Cortisol i EKF Biosen Clinic/GP. Rezultati: Bazalni nivoi kortizola su bili zna~ajno vi{i na 5 °C nego na 32 °C (u PCF grupi: P=0,0079); nakon mar{i- ranja na 5 °C kortizol opada u obe grupe a pove}an je na 32 °C samo u PCF grupi. Bazalni nivoi laktoze bili su vi{i na 32 °C samo u GCF grupi (porede}i sa PCF grupom, P=0,0014) i nakon mar{iranja (porede}i sa bazalnim vred- nostima, P=0,0002).",
publisher = "Society of Medical Biochemists of Serbia",
journal = "Journal of Medical Biochemistry",
title = "Cardiorespiratory fitness mediates cortisol and lactate responses to winter and summer marches, Kardiorespiratorni fitnes i njegov značaj u reakcijama kortizola i laktata prilikom zimskih i letnjih marševa",
volume = "43",
number = "1",
pages = "72-85",
doi = "10.5937/jomb0-44369"
}

Pešić, D., Đukić, M., Stanojević, I., Živković, V., Bolevich, S., Bolevich, S.,& Jakovljević, V.. (2024). Cardiorespiratory fitness mediates cortisol and lactate responses to winter and summer marches. in Journal of Medical Biochemistry
Society of Medical Biochemists of Serbia., 43(1), 72-85.
https://doi.org/10.5937/jomb0-44369

Pešić D, Đukić M, Stanojević I, Živković V, Bolevich S, Bolevich S, Jakovljević V. Cardiorespiratory fitness mediates cortisol and lactate responses to winter and summer marches. in Journal of Medical Biochemistry. 2024;43(1):72-85.
doi:10.5937/jomb0-44369 .

Pešić, Deniel, Đukić, Mirjana, Stanojević, Ivan, Živković, Vladimir, Bolevich, Sergey, Bolevich, Stefani, Jakovljević, Vladimir, "Cardiorespiratory fitness mediates cortisol and lactate responses to winter and summer marches" in Journal of Medical Biochemistry, 43, no. 1 (2024):72-85,
https://doi.org/10.5937/jomb0-44369 . .

TY  - CONF
AU  - Rajić, Jelena
AU  - Šobajić, Slađana
AU  - Vidović, Bojana
AU  - Bašić, Jasmina
AU  - Živković, Vladimir
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4588
AB  - A considerable interest has been developed over the years for fruits and vegetables
consumption due to their potential biological and health promoting effects. This effect is
attributed to antioxidants. Among the most important natural antioxidants are secondary
plants metabolites, polyphenols. Epidemiological studies indicate that an increase in the
consumption of fruits and vegetables is associated with a decrease in the incidence of
various diseases. The aim of this work was to estimate the intake of polyphenols in the adult
population of the Republic of Serbia based on literature data on polyphenol content in
certain foods and intake data obtained from the Bulletin - Household Budget Survey, 2019
(Statistical Office of the Republic of Serbia), as well as literature data on intake. Based on
literature data on the content of polyphenols in different food groups, it was determined that
the following food groups can be sources of polyphenols in the diet of the Serbian adult
population: vegetables, fruits, coffee, tea, cacao, chocolate, wine, nuts, and fruit juices. Using
the Statistical Office of the Republic of Serbia data, as well as the literature data on the
content of polyphenols in foods that are the major sources of polyphenols in the diet of the
adult Serbia population, the polyphenol intake was estimated. The daily intake of
polyphenols in the adult population of Serbia is about 500 mg. It is necessary to increase the
daily intake of polyphenols in the adult population in Serbia.
AB  - Veliko interesovanje poslednjih godina posvećeno je povećanom unosu voća, povrća i
pozitivnom uticaju na zdravlje. Ovaj efekat pripisuje se i antioksidansima. U najznačajnije
prirodne antioksidanse ubrajaju se sekundarni metaboliti biljaka, polifenoli. Epidemiološke
studije ukazuju da je poveć an unos voća i povrća povezan sa smanjenjem incidence različitih
vrsta bolesti. Cilj ovog rada je, da se na osnovu literaturnih podataka o sadržaju polifenola u
pojedinim namirnicama, na osnovu podataka o unosu namirnica dobijenih iz Biltena –
Anketa o potrošnji domaćinstva, 2019. (Republički zavod za statistiku, Republika Srbija), kao
i literaturnih podataka o unosu, proceni unos polifenola kod odraslog stanovništva
Republike Srbije. Na osnovu literaturnih podataka o sadržaju polifenola u različitim grupama
namirnica utvrđeno je da sledeće grupe namirnica mogu biti izvori polifenola u ishrani
odraslog stanovništva Republike Srbije: povrće, voće, kafa, čaj, kakao, čokolada, vino,
jezgrasto voće i voćni sokovi. Koristeći podatke Republičkog zavoda za statistiku Republike
Srbije, kao i literaturnih podataka za sadržaj polifenola u namirnicama koje su izvor
polifenola u ishrani odraslog stanovništva Srbije izvršena je procena unosa polifenola.
Dnevni unos polifenola kod odraslog stanovništva u Beogradu na osnovu dobijenih podataka
iz Ankete o potrošnji domaćinstva za 2019. godinu i uzimajući u obzir namirnice koji su po
literaturnim podacima izvor polifenola u ishrani odraslog stanovništva srbije iznosi oko 500
mg. Potrebno je povećati unos polifenola u ishrani stanovništva Republike Srbije.
PB  - Savez farmaceutskih udruženja Srbije (SFUS)
C3  - Arhiv za farmaciju
T1  - Major food sources of polyphenols in Serbian adult population
T1  - Procena dnevnog unosa polifenola u ishrani odraslih u Srbiji
VL  - 72
IS  - 4 suplement
SP  - S489
EP  - S490
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4588
ER  - 

@conference{
author = "Rajić, Jelena and Šobajić, Slađana and Vidović, Bojana and Bašić, Jasmina and Živković, Vladimir",
year = "2022",
abstract = "A considerable interest has been developed over the years for fruits and vegetables
consumption due to their potential biological and health promoting effects. This effect is
attributed to antioxidants. Among the most important natural antioxidants are secondary
plants metabolites, polyphenols. Epidemiological studies indicate that an increase in the
consumption of fruits and vegetables is associated with a decrease in the incidence of
various diseases. The aim of this work was to estimate the intake of polyphenols in the adult
population of the Republic of Serbia based on literature data on polyphenol content in
certain foods and intake data obtained from the Bulletin - Household Budget Survey, 2019
(Statistical Office of the Republic of Serbia), as well as literature data on intake. Based on
literature data on the content of polyphenols in different food groups, it was determined that
the following food groups can be sources of polyphenols in the diet of the Serbian adult
population: vegetables, fruits, coffee, tea, cacao, chocolate, wine, nuts, and fruit juices. Using
the Statistical Office of the Republic of Serbia data, as well as the literature data on the
content of polyphenols in foods that are the major sources of polyphenols in the diet of the
adult Serbia population, the polyphenol intake was estimated. The daily intake of
polyphenols in the adult population of Serbia is about 500 mg. It is necessary to increase the
daily intake of polyphenols in the adult population in Serbia., Veliko interesovanje poslednjih godina posvećeno je povećanom unosu voća, povrća i
pozitivnom uticaju na zdravlje. Ovaj efekat pripisuje se i antioksidansima. U najznačajnije
prirodne antioksidanse ubrajaju se sekundarni metaboliti biljaka, polifenoli. Epidemiološke
studije ukazuju da je poveć an unos voća i povrća povezan sa smanjenjem incidence različitih
vrsta bolesti. Cilj ovog rada je, da se na osnovu literaturnih podataka o sadržaju polifenola u
pojedinim namirnicama, na osnovu podataka o unosu namirnica dobijenih iz Biltena –
Anketa o potrošnji domaćinstva, 2019. (Republički zavod za statistiku, Republika Srbija), kao
i literaturnih podataka o unosu, proceni unos polifenola kod odraslog stanovništva
Republike Srbije. Na osnovu literaturnih podataka o sadržaju polifenola u različitim grupama
namirnica utvrđeno je da sledeće grupe namirnica mogu biti izvori polifenola u ishrani
odraslog stanovništva Republike Srbije: povrće, voće, kafa, čaj, kakao, čokolada, vino,
jezgrasto voće i voćni sokovi. Koristeći podatke Republičkog zavoda za statistiku Republike
Srbije, kao i literaturnih podataka za sadržaj polifenola u namirnicama koje su izvor
polifenola u ishrani odraslog stanovništva Srbije izvršena je procena unosa polifenola.
Dnevni unos polifenola kod odraslog stanovništva u Beogradu na osnovu dobijenih podataka
iz Ankete o potrošnji domaćinstva za 2019. godinu i uzimajući u obzir namirnice koji su po
literaturnim podacima izvor polifenola u ishrani odraslog stanovništva srbije iznosi oko 500
mg. Potrebno je povećati unos polifenola u ishrani stanovništva Republike Srbije.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Major food sources of polyphenols in Serbian adult population, Procena dnevnog unosa polifenola u ishrani odraslih u Srbiji",
volume = "72",
number = "4 suplement",
pages = "S489-S490",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4588"
}

Rajić, J., Šobajić, S., Vidović, B., Bašić, J.,& Živković, V.. (2022). Major food sources of polyphenols in Serbian adult population. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije (SFUS)., 72(4 suplement), S489-S490.
https://hdl.handle.net/21.15107/rcub_farfar_4588

Rajić J, Šobajić S, Vidović B, Bašić J, Živković V. Major food sources of polyphenols in Serbian adult population. in Arhiv za farmaciju. 2022;72(4 suplement):S489-S490.
https://hdl.handle.net/21.15107/rcub_farfar_4588 .

Rajić, Jelena, Šobajić, Slađana, Vidović, Bojana, Bašić, Jasmina, Živković, Vladimir, "Major food sources of polyphenols in Serbian adult population" in Arhiv za farmaciju, 72, no. 4 suplement (2022):S489-S490,
https://hdl.handle.net/21.15107/rcub_farfar_4588 .