TY  - JOUR
AU  - Gajić, Ina
AU  - Kabić, Jovana
AU  - Kekić, Dušan
AU  - Jovićević, Miloš
AU  - Milenković, Marina
AU  - Mitić-Ćulafić, Dragana
AU  - Trudić, Anika
AU  - Ranin, Lazar
AU  - Opavski, Nataša
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4083
AB  - Antimicrobial resistance (AMR) has emerged as a major threat to public health globally. Accurate and rapid detection of resistance to antimicrobial drugs, and subsequent appropriate antimicrobial treatment, combined with antimicrobial stewardship, are essential for controlling the emergence and spread of AMR. This article reviews common antimicrobial susceptibility testing (AST) methods and relevant issues concerning the advantages and disadvantages of each method. Although accurate, classic technologies used in clinical microbiology to profile antimicrobial susceptibility are time-consuming and relatively expensive. As a result, physicians often prescribe empirical antimicrobial therapies and broad-spectrum antibiotics. Although recently developed AST systems have shown advantages over traditional methods in terms of testing speed and the potential for providing a deeper insight into resistance mechanisms, extensive validation is required to translate these methodologies to clinical practice. With a continuous increase in antimicrobial resistance, additional efforts are needed to develop innovative, rapid, accurate, and portable diagnostic tools for AST. The wide implementation of novel devices would enable the identification of the optimal treatment approaches and the surveillance of antibiotic resistance in health, agriculture, and the environment, allowing monitoring and better tackling the emergence of AMR.
PB  - MDPI
T2  - Antibiotics
T1  - Antimicrobial Susceptibility Testing: A Comprehensive Review of Currently Used Methods
VL  - 11
IS  - 4
DO  - 10.3390/antibiotics11040427
ER  - 

@article{
author = "Gajić, Ina and Kabić, Jovana and Kekić, Dušan and Jovićević, Miloš and Milenković, Marina and Mitić-Ćulafić, Dragana and Trudić, Anika and Ranin, Lazar and Opavski, Nataša",
year = "2022",
abstract = "Antimicrobial resistance (AMR) has emerged as a major threat to public health globally. Accurate and rapid detection of resistance to antimicrobial drugs, and subsequent appropriate antimicrobial treatment, combined with antimicrobial stewardship, are essential for controlling the emergence and spread of AMR. This article reviews common antimicrobial susceptibility testing (AST) methods and relevant issues concerning the advantages and disadvantages of each method. Although accurate, classic technologies used in clinical microbiology to profile antimicrobial susceptibility are time-consuming and relatively expensive. As a result, physicians often prescribe empirical antimicrobial therapies and broad-spectrum antibiotics. Although recently developed AST systems have shown advantages over traditional methods in terms of testing speed and the potential for providing a deeper insight into resistance mechanisms, extensive validation is required to translate these methodologies to clinical practice. With a continuous increase in antimicrobial resistance, additional efforts are needed to develop innovative, rapid, accurate, and portable diagnostic tools for AST. The wide implementation of novel devices would enable the identification of the optimal treatment approaches and the surveillance of antibiotic resistance in health, agriculture, and the environment, allowing monitoring and better tackling the emergence of AMR.",
publisher = "MDPI",
journal = "Antibiotics",
title = "Antimicrobial Susceptibility Testing: A Comprehensive Review of Currently Used Methods",
volume = "11",
number = "4",
doi = "10.3390/antibiotics11040427"
}

Gajić, I., Kabić, J., Kekić, D., Jovićević, M., Milenković, M., Mitić-Ćulafić, D., Trudić, A., Ranin, L.,& Opavski, N.. (2022). Antimicrobial Susceptibility Testing: A Comprehensive Review of Currently Used Methods. in Antibiotics
MDPI., 11(4).
https://doi.org/10.3390/antibiotics11040427

Gajić I, Kabić J, Kekić D, Jovićević M, Milenković M, Mitić-Ćulafić D, Trudić A, Ranin L, Opavski N. Antimicrobial Susceptibility Testing: A Comprehensive Review of Currently Used Methods. in Antibiotics. 2022;11(4).
doi:10.3390/antibiotics11040427 .

Gajić, Ina, Kabić, Jovana, Kekić, Dušan, Jovićević, Miloš, Milenković, Marina, Mitić-Ćulafić, Dragana, Trudić, Anika, Ranin, Lazar, Opavski, Nataša, "Antimicrobial Susceptibility Testing: A Comprehensive Review of Currently Used Methods" in Antibiotics, 11, no. 4 (2022),
https://doi.org/10.3390/antibiotics11040427 . .