TY  - CONF
AU  - Cilović, Ermina
AU  - Brantner, Adelheid
AU  - Tran, Huyen Thi
AU  - Arsenijević, Jelena
AU  - Maksimović, Zoran
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5289
AB  - Telekia speciosa (Schreb.) Baumg., porodica Asteraceae se tradicionalno koristi kao lijek za bronhijalnu astmu u zemljama
Balkanskog poluostrva. Cilj istraživanja je da se odredi ukupan sadržaj fenola i antioksidativni kapacitet metanolnih
ekstrakata nadzemnih dijelova i korijena T. speciosae sakupljene u ljeto i jesen 2015. godine na Karauli, Olovo, Bosna i
Hercegovina (BiH) te da se analiziraju fenolne kiseline u pomenutim ekstraktima.
Za određivanje ukupnog sadržaja fenola i in vitro antioksidativnog kapaciteta u ekstraktima, korištene su spektrofotometrijske
metode. Fenolne kiseline su analizirane pomoću RP-HPLC metode.
Ukupan sadržaj fenola za T. speciosa ekstrakte je bio od 28,84 do 146,06 mg galne kiseline po g ekstrakta. IC50 vrijednosti su
bile od 112,57 do preko 800,00 μg ml-1 dok su se FRAP vrijednosti kretale od 189,31 do 1329,56 μmol Fe2+ po g ekstrakta.
Sadržaj hlorogenske kiseline je bio od 26,80 do 968,80 mg po 100 g ekstrakta.
Ekstrakti korijena T. speciosae imali su statistički značajno veći antioksidativni kapacitet u poređenju sa nadzemnim
dijelovima biljke dok je antioksidativni kapacitet ekstrakata sakupljenih u ljeto statistički značajno veći veći u odnosu na
ekstrakte sakupljene u jesen. Statistički značajna razlika u sadržaju hlorogenske kiseline u ekstraktima nadzemnog dijela i
korjena T. speciosae između ljeta i jeseni može se objasniti razlikom u temperaturi, različitom stepenu vlage i deponovanju
aktivnih supstanci u korijenu tokom zimskog perioda.
Koliko nam je poznato, hemijski sastav korijena kao i antioksidativni kapacitet ekstrakata T. speciosae do sada nisu
istraživani. Hlorogenska kiselina prisutna u ekstraktima daje mogućnost za dalja ispitivanja i širu primjenu T. speciosae
zbog njenog različitog farmakološkog djelovanja.
AB  - Telekia speciosa (Schreb.) Baumg., family Asteraceae is traditionally used as a remedy for bronchial asthma in Balkan
countries. The aim of the present study was to determine the total phenol content and the antioxidant capacity of the
methanol extracts from the aerial parts and the roots of T. speciosa collected in the summer and the autumn 2015, at
Karaula, Olovo, Bosnia and Herzegovina (BiH) and to analyse the phenolic acids in the mentioned extracts.
Spectrophotometric methods were used for the determination of the total phenol content and in vitro antioxidant capacity
of the extracts. Phenolic acids were analysed using the RP-HPLC method.
The total phenol content for T. speciosa extracts was from 28.84 to 146.06 mg gallic acid per g extract. IC50 values were from
112.57 to more then 800.00 μg ml-1 while FRAP values were from 189.31 to 1329.56 μmol Fe2+ per g extract. Chlorogenic
acid content was from 26.80 do 968.80 mg per 100 g extract.
Extracts of T. speciosa roots had significantly higher antioxidant capacity in comparison to the aerial parts while the
antioxidant capacity of the extracts collected in the summer was significantly higher in comparison to the extracts
collected in the autumn. Statistically significant difference in the chlorogenic acid content in T. speciosa aerial parts and
roots extracts between summer and autumn can be explained by a difference in temperature, a different degree of humidity
and storing active principles in the root during the cold days.
As we know, the chemical composition of the root and the antioxidant capacity of T. speciosa extracts were not investigated
by now. Chlorogenic acid presented in the extracts gives the opportunity for further investigations and additional
application of T. speciosa because of its many pharmacological activities.
PB  - Tuzla: Komora magistara farmacije Tuzlanskog kantona
C3  - Zbornik radova sa simpozija magistara farmacije Tuzlanskog kantona, Šesti simpozij: „Antioksidansi, značaj i upotreba“
T1  - Antioksidativni kapacitet ekstrakata Telekia speciosa (Schreb.) Baumg.
T1  - Antioxidative capacity of Telekia speciosa (Schreb.) Baumg. extracts
VL  - 6
IS  - 6
SP  - 17
EP  - 23
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5289
ER  - 

@conference{
author = "Cilović, Ermina and Brantner, Adelheid and Tran, Huyen Thi and Arsenijević, Jelena and Maksimović, Zoran",
year = "2019",
abstract = "Telekia speciosa (Schreb.) Baumg., porodica Asteraceae se tradicionalno koristi kao lijek za bronhijalnu astmu u zemljama
Balkanskog poluostrva. Cilj istraživanja je da se odredi ukupan sadržaj fenola i antioksidativni kapacitet metanolnih
ekstrakata nadzemnih dijelova i korijena T. speciosae sakupljene u ljeto i jesen 2015. godine na Karauli, Olovo, Bosna i
Hercegovina (BiH) te da se analiziraju fenolne kiseline u pomenutim ekstraktima.
Za određivanje ukupnog sadržaja fenola i in vitro antioksidativnog kapaciteta u ekstraktima, korištene su spektrofotometrijske
metode. Fenolne kiseline su analizirane pomoću RP-HPLC metode.
Ukupan sadržaj fenola za T. speciosa ekstrakte je bio od 28,84 do 146,06 mg galne kiseline po g ekstrakta. IC50 vrijednosti su
bile od 112,57 do preko 800,00 μg ml-1 dok su se FRAP vrijednosti kretale od 189,31 do 1329,56 μmol Fe2+ po g ekstrakta.
Sadržaj hlorogenske kiseline je bio od 26,80 do 968,80 mg po 100 g ekstrakta.
Ekstrakti korijena T. speciosae imali su statistički značajno veći antioksidativni kapacitet u poređenju sa nadzemnim
dijelovima biljke dok je antioksidativni kapacitet ekstrakata sakupljenih u ljeto statistički značajno veći veći u odnosu na
ekstrakte sakupljene u jesen. Statistički značajna razlika u sadržaju hlorogenske kiseline u ekstraktima nadzemnog dijela i
korjena T. speciosae između ljeta i jeseni može se objasniti razlikom u temperaturi, različitom stepenu vlage i deponovanju
aktivnih supstanci u korijenu tokom zimskog perioda.
Koliko nam je poznato, hemijski sastav korijena kao i antioksidativni kapacitet ekstrakata T. speciosae do sada nisu
istraživani. Hlorogenska kiselina prisutna u ekstraktima daje mogućnost za dalja ispitivanja i širu primjenu T. speciosae
zbog njenog različitog farmakološkog djelovanja., Telekia speciosa (Schreb.) Baumg., family Asteraceae is traditionally used as a remedy for bronchial asthma in Balkan
countries. The aim of the present study was to determine the total phenol content and the antioxidant capacity of the
methanol extracts from the aerial parts and the roots of T. speciosa collected in the summer and the autumn 2015, at
Karaula, Olovo, Bosnia and Herzegovina (BiH) and to analyse the phenolic acids in the mentioned extracts.
Spectrophotometric methods were used for the determination of the total phenol content and in vitro antioxidant capacity
of the extracts. Phenolic acids were analysed using the RP-HPLC method.
The total phenol content for T. speciosa extracts was from 28.84 to 146.06 mg gallic acid per g extract. IC50 values were from
112.57 to more then 800.00 μg ml-1 while FRAP values were from 189.31 to 1329.56 μmol Fe2+ per g extract. Chlorogenic
acid content was from 26.80 do 968.80 mg per 100 g extract.
Extracts of T. speciosa roots had significantly higher antioxidant capacity in comparison to the aerial parts while the
antioxidant capacity of the extracts collected in the summer was significantly higher in comparison to the extracts
collected in the autumn. Statistically significant difference in the chlorogenic acid content in T. speciosa aerial parts and
roots extracts between summer and autumn can be explained by a difference in temperature, a different degree of humidity
and storing active principles in the root during the cold days.
As we know, the chemical composition of the root and the antioxidant capacity of T. speciosa extracts were not investigated
by now. Chlorogenic acid presented in the extracts gives the opportunity for further investigations and additional
application of T. speciosa because of its many pharmacological activities.",
publisher = "Tuzla: Komora magistara farmacije Tuzlanskog kantona",
journal = "Zbornik radova sa simpozija magistara farmacije Tuzlanskog kantona, Šesti simpozij: „Antioksidansi, značaj i upotreba“",
title = "Antioksidativni kapacitet ekstrakata Telekia speciosa (Schreb.) Baumg., Antioxidative capacity of Telekia speciosa (Schreb.) Baumg. extracts",
volume = "6",
number = "6",
pages = "17-23",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5289"
}

Cilović, E., Brantner, A., Tran, H. T., Arsenijević, J.,& Maksimović, Z.. (2019). Antioksidativni kapacitet ekstrakata Telekia speciosa (Schreb.) Baumg.. in Zbornik radova sa simpozija magistara farmacije Tuzlanskog kantona, Šesti simpozij: „Antioksidansi, značaj i upotreba“
Tuzla: Komora magistara farmacije Tuzlanskog kantona., 6(6), 17-23.
https://hdl.handle.net/21.15107/rcub_farfar_5289

Cilović E, Brantner A, Tran HT, Arsenijević J, Maksimović Z. Antioksidativni kapacitet ekstrakata Telekia speciosa (Schreb.) Baumg.. in Zbornik radova sa simpozija magistara farmacije Tuzlanskog kantona, Šesti simpozij: „Antioksidansi, značaj i upotreba“. 2019;6(6):17-23.
https://hdl.handle.net/21.15107/rcub_farfar_5289 .

Cilović, Ermina, Brantner, Adelheid, Tran, Huyen Thi, Arsenijević, Jelena, Maksimović, Zoran, "Antioksidativni kapacitet ekstrakata Telekia speciosa (Schreb.) Baumg." in Zbornik radova sa simpozija magistara farmacije Tuzlanskog kantona, Šesti simpozij: „Antioksidansi, značaj i upotreba“, 6, no. 6 (2019):17-23,
https://hdl.handle.net/21.15107/rcub_farfar_5289 .

TY  - JOUR
AU  - Cilović, Ermina
AU  - Brantner, Adelheid
AU  - Tran, Huyen Thi
AU  - Arsenijević, Jelena
AU  - Maksimović, Zoran
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5287
AB  - The aim of the present study was to analyse the methanol extracts from the aerial and the under-
ground parts of Telekia speciosa (Schreb.) Baumg by HPLC and determine their antioxidant capacity. In addi-
tion, volatiles from both parts of the plant were analysed. The chlorogenic acid (CGA) and caffeic acid derivatives
were present in the extracts. The CGA content was 977.8±85 mg per 100 g extract for underground and 272.0±18
mg per100 g extract for aerial parts of T. speciosa. The antioxidant capacity, determined by DPPH and FRAP
method, was on average three and a half times higher for the extract of the underground parts in comparison
with the extract of the aerial plant parts. The volatile constituents determined by GC-FID/MS were characterized
by the presence of a high concentration of oxygenated sesquiterpenes. The obtained results contribute to better
knowledge of phytochemical properties of T. speciosa, which is traditionally used in bronchial asthma therapy.
PB  - Faculty of Technology, University in Tuzla, (Zenodo?)
T2  - Technologica Acta
T1  - Methanol Extracts and Volatiles of Telekia speciosa (Schreb.) Baumg. from Bosnia and Herzegovina
VL  - 12
IS  - 1
SP  - 9
EP  - 13
DO  - 10.5281/zenodo.3268729
ER  - 

@article{
author = "Cilović, Ermina and Brantner, Adelheid and Tran, Huyen Thi and Arsenijević, Jelena and Maksimović, Zoran",
year = "2019",
abstract = "The aim of the present study was to analyse the methanol extracts from the aerial and the under-
ground parts of Telekia speciosa (Schreb.) Baumg by HPLC and determine their antioxidant capacity. In addi-
tion, volatiles from both parts of the plant were analysed. The chlorogenic acid (CGA) and caffeic acid derivatives
were present in the extracts. The CGA content was 977.8±85 mg per 100 g extract for underground and 272.0±18
mg per100 g extract for aerial parts of T. speciosa. The antioxidant capacity, determined by DPPH and FRAP
method, was on average three and a half times higher for the extract of the underground parts in comparison
with the extract of the aerial plant parts. The volatile constituents determined by GC-FID/MS were characterized
by the presence of a high concentration of oxygenated sesquiterpenes. The obtained results contribute to better
knowledge of phytochemical properties of T. speciosa, which is traditionally used in bronchial asthma therapy.",
publisher = "Faculty of Technology, University in Tuzla, (Zenodo?)",
journal = "Technologica Acta",
title = "Methanol Extracts and Volatiles of Telekia speciosa (Schreb.) Baumg. from Bosnia and Herzegovina",
volume = "12",
number = "1",
pages = "9-13",
doi = "10.5281/zenodo.3268729"
}

Cilović, E., Brantner, A., Tran, H. T., Arsenijević, J.,& Maksimović, Z.. (2019). Methanol Extracts and Volatiles of Telekia speciosa (Schreb.) Baumg. from Bosnia and Herzegovina. in Technologica Acta
Faculty of Technology, University in Tuzla, (Zenodo?)., 12(1), 9-13.
https://doi.org/10.5281/zenodo.3268729

Cilović E, Brantner A, Tran HT, Arsenijević J, Maksimović Z. Methanol Extracts and Volatiles of Telekia speciosa (Schreb.) Baumg. from Bosnia and Herzegovina. in Technologica Acta. 2019;12(1):9-13.
doi:10.5281/zenodo.3268729 .

Cilović, Ermina, Brantner, Adelheid, Tran, Huyen Thi, Arsenijević, Jelena, Maksimović, Zoran, "Methanol Extracts and Volatiles of Telekia speciosa (Schreb.) Baumg. from Bosnia and Herzegovina" in Technologica Acta, 12, no. 1 (2019):9-13,
https://doi.org/10.5281/zenodo.3268729 . .