@conference{
author = "Petrić, M. and Ilić, K. and Tasić, Ljiljana",
year = "2009",
abstract = "OBJECTIVES: To investigate drug use six months before (SMBP) and during preg-
nancy (DP) among Serbian pregnant women (SPW). METHODS: Pharmacy based
cross-sectional survey was conducted among SPW between March through April
2009. Specially designed questionnaire was used for collecting data on socio-demo-
graphics, health status, and drug (Rx and over the counter) use. Vitamin and iron
supplements were not included in the analysis. RESULTS: 260 SPW completed the
questionnaire. 69.6% of SPW were 25–34 years old, 75.8% lived in the city area, the
majority were high school or college graduates, and 55.4% were pregnant with their
first child. 9.4% of SPW had a chronic disease. There was not a statistically significant
decrease in the percentage of SPW taking drugs DP compared to SMBP (53.9% and
53.0%, respectively), as well as in an average number of drugs taken (1.54 o 0.73 and
1.45 o 0.66 drugs/women, respectively (range 1 to 4 before and during pregnancy)).
The most frequently used drug classes by SPW were: analgetics/antipyretics, hormones,
antiinfectives, tocolitics and anti-hypertensives (25.5%, 25.5%, 19.7%, 13.7%, and
7.3%, respectively). The most frequently used analgetic/antipyretic was paracetamol
(62.83%), while the most frequently used anti-infectives were penicillins and cepha-
losporins (77.0%). The only used tocolitics were fenoterol and hexoprenaline and the
only used hormones were dydrogesterone and progesterone. Drugs that were used
belonged to these FDA fetal risk categories B, C, and D (diazepam, alprazolam and
diclofenac in the 3 rd trimester) (52.6%, 26.3%, and 15.8% respectively). SPW did not
use drugs in the FDA category X. Before pregnancy folic acid usage was low (5.5%
PW) while during the 1st, 2nd and 3rd trimester of pregnancy usage was 69.96%,
15.05%, 5.93%, respectively. CONCLUSIONS: Differences in drug use DP and
SMBP among SPW was negligible. The most frequently used drug classes during
pregnancy were: analgetics/antipyretics, hormones, antiinfectives, tocolitics and
antihypertensives.",
publisher = "Elsevier",
journal = "Value in Health",
title = "Drug use before and during pregnancy in republic of Serbia",
volume = "12",
number = "7",
pages = "A296-A296",
doi = "10.1016/S1098-3015(10)74452-1"
}