TY  - JOUR
AU  - Vicković, Sanja
AU  - Zdravković, Ranko
AU  - Maričić-Prijić, Sanja
AU  - Nikolić, Dragan
AU  - Pap, Dragana
AU  - Čolak, Emina
AU  - Jovičić, Snežana
PY  - 2023
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85151461118&doi=10.5937%2fjomb0-42011&partnerID=40&md5=e093411634659d1acbf5cdbb88450218
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4655
AB  - Background: Surgical stress and pain result in activation of hypothalamus-pituitary-adrenal axis. The aim of this study was to establish the effects of postoperative pain and various modalities of analgesic administration on salivary and serum cortisol levels, as well as to establish the validity of salivary cortisol as a stress indicator in surgical patients. Methods: A randomized controlled trial involved 60 patients scheduled for elective abdominal aortic aneurysm surgery. Patients were randomly divided into two groups depending on the model of postoperative analgesia. The first group (MI – morphine intermittently) included patients given morphine doses 0.1 mg/kg/6h s.c. intermittently. The second group (MPCA – morphine patient-controlled analgesia) included patients who received morphine via the PCA system – intravenous administration of morphine adjusted to a dose of 1 mg per shot and a lockout interval of 6 minutes. Results: The intensity of pain did not significantly vary until the hour 10 post-surgery. However, in the period from hour 10 to hour 18 post-surgery, higher intensity of pain was reported in group MPCA (P < 0.05). Hemodynamic instability was more prevalent in the MI group (40.0% vs 6.7%, P = 0.0048). Serum cortisol levels were almost identical in both groups (MI 509.4 nmol/L vs MPCA 511.0 nmol/L, P = 0.1473). Higher values of salivary cortisol were recorded in group MPCA; however, the difference was not statistically significant (47.1 nmol/L vs 116.3 nmol/L, P = 0.0970). Conclusion: Our study confirmed that salivary cortisol is a more sensitive stress biomarker in surgical patients as compared to blood cortisol.
AB  - Uvod: Hirur{ki stres i bol su uzrok aktivacije hipotalamus- no-hipofizno-nadbubre`ne osovine. Cilj ove studije bio je da se utvrdi uticaj postoperativnog bola i razli~itih vidova administracije analgetika na vrednosti kortizola u serumu i salivi, kao i da se utvrdi da li je salivarni kortizol dobar poka- zatelj stresa kod hirur{kih pacijenata. Metode: Randomizovana kontrolisana studija koja je uklju- ~ila 60 pacijenata primljenih za elektivnu operaciju ane- urizme abdominalne aorte. Pacijenti su metodom slu~ajnog izbora podeljeni u dve grupe u zavisnosti od modela post- operativne analgezije. Prvu grupu (MI – intermitentna pri- mena morfina) su ~inili pacijenti koji su dobijali morfin intermitentno u dozi od 0.1 mg/kg/6h s.c. U drugoj grupi (MPCA – analgezija morfinom kontrolisana od strane paci- jenta) su bili pacijenti koji su dobijali morfin takozvanom PCA metodom – intravenska primena morfina 1 pritisak/1 mg, interval 6 minuta. Rezultati: Intenzitet bola se nije zna~ajno razlikovao do desetog sata nakon operacije. Me|utim, u periodu od de- setog do osamnaestog sata nakon operacije bol je bio izra`eniji u MPCA grupi (P < 0.05). Hemodinamska nesta- bilnost je bila zastupljenija u grupi MI (40.0% vs 6.7%, P = 0.0048). Serumski kortizol bio je gotovo identi~an po gru- pama (MI 509.4 nmol/L vs MPCA 511.0 nmol/L, P = 0.1473). Salivarni kortizol je bio vi{i u grupi MPCA ali razika nije statisti~ki zna~ajna (47.1 nmol/L vs 116.3 nmol/L, P = 0.0970). Zaklju~ak: Na{a studija je pokazala da je salivarni kortizol senzitivniji biomarker stresa kod hirur{kih pacijenata u odnosu na serumski kortizol.
PB  - Society of Medical Biochemists of Serbia
T2  - Journal of Medical Biochemistry
T1  - Salivary cortisol as a biomarker of stress in surgical patients
T1  - Salivarni kortizol kao biomarker stresa kod hirurških pacijenata
VL  - 42
SP  - 1
EP  - 7
DO  - 10.5937/jomb0-42011
ER  - 

@article{
author = "Vicković, Sanja and Zdravković, Ranko and Maričić-Prijić, Sanja and Nikolić, Dragan and Pap, Dragana and Čolak, Emina and Jovičić, Snežana",
year = "2023",
abstract = "Background: Surgical stress and pain result in activation of hypothalamus-pituitary-adrenal axis. The aim of this study was to establish the effects of postoperative pain and various modalities of analgesic administration on salivary and serum cortisol levels, as well as to establish the validity of salivary cortisol as a stress indicator in surgical patients. Methods: A randomized controlled trial involved 60 patients scheduled for elective abdominal aortic aneurysm surgery. Patients were randomly divided into two groups depending on the model of postoperative analgesia. The first group (MI – morphine intermittently) included patients given morphine doses 0.1 mg/kg/6h s.c. intermittently. The second group (MPCA – morphine patient-controlled analgesia) included patients who received morphine via the PCA system – intravenous administration of morphine adjusted to a dose of 1 mg per shot and a lockout interval of 6 minutes. Results: The intensity of pain did not significantly vary until the hour 10 post-surgery. However, in the period from hour 10 to hour 18 post-surgery, higher intensity of pain was reported in group MPCA (P < 0.05). Hemodynamic instability was more prevalent in the MI group (40.0% vs 6.7%, P = 0.0048). Serum cortisol levels were almost identical in both groups (MI 509.4 nmol/L vs MPCA 511.0 nmol/L, P = 0.1473). Higher values of salivary cortisol were recorded in group MPCA; however, the difference was not statistically significant (47.1 nmol/L vs 116.3 nmol/L, P = 0.0970). Conclusion: Our study confirmed that salivary cortisol is a more sensitive stress biomarker in surgical patients as compared to blood cortisol., Uvod: Hirur{ki stres i bol su uzrok aktivacije hipotalamus- no-hipofizno-nadbubre`ne osovine. Cilj ove studije bio je da se utvrdi uticaj postoperativnog bola i razli~itih vidova administracije analgetika na vrednosti kortizola u serumu i salivi, kao i da se utvrdi da li je salivarni kortizol dobar poka- zatelj stresa kod hirur{kih pacijenata. Metode: Randomizovana kontrolisana studija koja je uklju- ~ila 60 pacijenata primljenih za elektivnu operaciju ane- urizme abdominalne aorte. Pacijenti su metodom slu~ajnog izbora podeljeni u dve grupe u zavisnosti od modela post- operativne analgezije. Prvu grupu (MI – intermitentna pri- mena morfina) su ~inili pacijenti koji su dobijali morfin intermitentno u dozi od 0.1 mg/kg/6h s.c. U drugoj grupi (MPCA – analgezija morfinom kontrolisana od strane paci- jenta) su bili pacijenti koji su dobijali morfin takozvanom PCA metodom – intravenska primena morfina 1 pritisak/1 mg, interval 6 minuta. Rezultati: Intenzitet bola se nije zna~ajno razlikovao do desetog sata nakon operacije. Me|utim, u periodu od de- setog do osamnaestog sata nakon operacije bol je bio izra`eniji u MPCA grupi (P < 0.05). Hemodinamska nesta- bilnost je bila zastupljenija u grupi MI (40.0% vs 6.7%, P = 0.0048). Serumski kortizol bio je gotovo identi~an po gru- pama (MI 509.4 nmol/L vs MPCA 511.0 nmol/L, P = 0.1473). Salivarni kortizol je bio vi{i u grupi MPCA ali razika nije statisti~ki zna~ajna (47.1 nmol/L vs 116.3 nmol/L, P = 0.0970). Zaklju~ak: Na{a studija je pokazala da je salivarni kortizol senzitivniji biomarker stresa kod hirur{kih pacijenata u odnosu na serumski kortizol.",
publisher = "Society of Medical Biochemists of Serbia",
journal = "Journal of Medical Biochemistry",
title = "Salivary cortisol as a biomarker of stress in surgical patients, Salivarni kortizol kao biomarker stresa kod hirurških pacijenata",
volume = "42",
pages = "1-7",
doi = "10.5937/jomb0-42011"
}

Vicković, S., Zdravković, R., Maričić-Prijić, S., Nikolić, D., Pap, D., Čolak, E.,& Jovičić, S.. (2023). Salivary cortisol as a biomarker of stress in surgical patients. in Journal of Medical Biochemistry
Society of Medical Biochemists of Serbia., 42, 1-7.
https://doi.org/10.5937/jomb0-42011

Vicković S, Zdravković R, Maričić-Prijić S, Nikolić D, Pap D, Čolak E, Jovičić S. Salivary cortisol as a biomarker of stress in surgical patients. in Journal of Medical Biochemistry. 2023;42:1-7.
doi:10.5937/jomb0-42011 .

Vicković, Sanja, Zdravković, Ranko, Maričić-Prijić, Sanja, Nikolić, Dragan, Pap, Dragana, Čolak, Emina, Jovičić, Snežana, "Salivary cortisol as a biomarker of stress in surgical patients" in Journal of Medical Biochemistry, 42 (2023):1-7,
https://doi.org/10.5937/jomb0-42011 . .

TY  - JOUR
AU  - Nikolić, Ljubinka
AU  - Čakić, Saša
AU  - Perunović, Neda
AU  - Čolak, Emina
AU  - Kotur-Stevuljević, Jelena
AU  - Janković, Saša
AU  - Đurić, Milanko
AU  - Plećaš, Darko
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3590
AB  - Bacground/Aim. Preterm birth is defined as a delivery prior to the completed 37th week of gestation. Literature data suggested that periodontal processes may influence to the feto-placental unit and induce preterm delivery. The degree of the periodontal disease is influenced by secretor status. Pro-inflammatory cytokines are involved in periodontitis as well as in delivery. The combined influence of these factors on the risk of preterm birth has not been explored. The aim of our study was to investigate the associations between periodontal diseases, secretor status, and interleukin-1-β (IL1-ß) and prostaglandine E2 (PGE2) levels in women delivered preterm. Methods. The study included 56 preterm delivery women and 56 women delivered at term as a control group, aged between 17 and 41 years. Periodontal examination, blood and saliva sampling were performed within 48 hours following delivery. Secretor phenotype was determined by hemagglutination inhibition method. The concentrations of IL1-ß and PGE2 were measured by high sensitivity Enzyme-linked Immunosorbent Assay (ELISA). Results. In the pre-term birth group there were 66.1% of women with periodontitis, while in the control one there were 12.5% (p < 0.01). Concentrations of IL1-ß and PGE2 in plasma were significantly higher in the non-secretor group of women who gave birth pre-term and had periodontitis comparing to other groups. There was a significant correlation between salivary and plasma levels of PGE2 and IL1-ß in the preterm birth group (R = 0.416, p = 0.017 and R = -0.592, p < 0.001, respectively). There were no such correlations in women who delivered at term. Conclusion. Our results support the hypothesis that non-secretor phenotype and periodontitis are at least in part responsible for pathogenesis of preterm birth. This probability of negative impact of non-secretor status cannot be ignored. These findings support the need for additional research into the biology of human parturition. © 2020 Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.
AB  - Uvod/Cilj. Prevremeni porođaj se definiše kao porođaj pre navršene 37 nedelje gestacije. Podaci iz literature govore u prilog tome da periodontalni procesi mogu uticati na fetoplacentalnu jedinicu i indukovati preterminski porođaj. Sekretorni status može uticati na stepen periodontalne bolesti. Proinflamatorni citokini imaju uticaj na periodontitis kao i na porođaj. Kombinovani uticaj ovih faktora rizika za prevremeni porođaj nije dovoljno istražen. Cilj ove studije je bio da istraži povezanost između periodontalne bolesti, sekretornog statusa, nivoa interleukina 1-b (IL1-b) i prostaglandina E2 (PGE2) kod žena koje su imale prevremeni porođaj. Metode. Studijom je bilo obuhvaćeno 56 žena, koje su imale prevremen porođaj i 56 žena u kontrolnoj grupi koje su se porodile u terminu, starosti između 17 i 41 godine. Periodontalni pregled, uzorkovanje krvi i salive je izvršeno u prvih 48 sati po porođaju. Sekretorni status je određen metodom inhibicije hemaglutinacije. Koncentracije IL1-b i PGE2 su merene visoko senzitivnim Enzyme-linked Immunosorbent Assay (ELISA) testom. Rezultati. U grupi prevremenih porođaja bilo je 66,1% žena sa periodontitisom, a u kontrolnoj grupi 12,5% (p < 0.01). Prevremeno porođene žena, nesekretori sa periodontitisom imale su u plazmi značajno više vrednosti IL 1-b i PGE 2 u odnosu na ostale grupe (p < 0,01). U grupi prevremeno porođenih žena postojala je značajna korelacija između salivarnih i plazmatskih koncentracija PGE2 i IL1-b (R = 0.416, p = 0.017 i R = -0,592, p < 0,001, redom). Ove korelacije nisu postojale kod žena koje su imale terminski porođaj. Zaključak. Naši rezultati podržavaju hipotezu da su sekretorni status i periodontitis, bar delimično, odgovorni za patogenezu preterminskog porođaja. Verovatnoća negativnog uticaja nesekretornog statusa se ne sme ignorisati. Ovi zaključci ukazuju na potrebu za dodatnim istraživanjima porođaja.
PB  - Beograd : Vojnomedicinska akademija - Institut za naučne informacije
T2  - Vojnosanitetski pregled
T1  - Salivary and plasma inflammatory mediators and secretory status in preterm delivery women with periodontitis - a cross sectional study
T1  - Salivarni i inflamatorni medijatori plazme i sekretorni status prevremeno porođenih žena sa periodontitisom – studija preseka
VL  - 77
IS  - 3
SP  - 247
EP  - 255
DO  - 10.2298/VSP171106066N
ER  - 

@article{
author = "Nikolić, Ljubinka and Čakić, Saša and Perunović, Neda and Čolak, Emina and Kotur-Stevuljević, Jelena and Janković, Saša and Đurić, Milanko and Plećaš, Darko",
year = "2020",
abstract = "Bacground/Aim. Preterm birth is defined as a delivery prior to the completed 37th week of gestation. Literature data suggested that periodontal processes may influence to the feto-placental unit and induce preterm delivery. The degree of the periodontal disease is influenced by secretor status. Pro-inflammatory cytokines are involved in periodontitis as well as in delivery. The combined influence of these factors on the risk of preterm birth has not been explored. The aim of our study was to investigate the associations between periodontal diseases, secretor status, and interleukin-1-β (IL1-ß) and prostaglandine E2 (PGE2) levels in women delivered preterm. Methods. The study included 56 preterm delivery women and 56 women delivered at term as a control group, aged between 17 and 41 years. Periodontal examination, blood and saliva sampling were performed within 48 hours following delivery. Secretor phenotype was determined by hemagglutination inhibition method. The concentrations of IL1-ß and PGE2 were measured by high sensitivity Enzyme-linked Immunosorbent Assay (ELISA). Results. In the pre-term birth group there were 66.1% of women with periodontitis, while in the control one there were 12.5% (p < 0.01). Concentrations of IL1-ß and PGE2 in plasma were significantly higher in the non-secretor group of women who gave birth pre-term and had periodontitis comparing to other groups. There was a significant correlation between salivary and plasma levels of PGE2 and IL1-ß in the preterm birth group (R = 0.416, p = 0.017 and R = -0.592, p < 0.001, respectively). There were no such correlations in women who delivered at term. Conclusion. Our results support the hypothesis that non-secretor phenotype and periodontitis are at least in part responsible for pathogenesis of preterm birth. This probability of negative impact of non-secretor status cannot be ignored. These findings support the need for additional research into the biology of human parturition. © 2020 Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved., Uvod/Cilj. Prevremeni porođaj se definiše kao porođaj pre navršene 37 nedelje gestacije. Podaci iz literature govore u prilog tome da periodontalni procesi mogu uticati na fetoplacentalnu jedinicu i indukovati preterminski porođaj. Sekretorni status može uticati na stepen periodontalne bolesti. Proinflamatorni citokini imaju uticaj na periodontitis kao i na porođaj. Kombinovani uticaj ovih faktora rizika za prevremeni porođaj nije dovoljno istražen. Cilj ove studije je bio da istraži povezanost između periodontalne bolesti, sekretornog statusa, nivoa interleukina 1-b (IL1-b) i prostaglandina E2 (PGE2) kod žena koje su imale prevremeni porođaj. Metode. Studijom je bilo obuhvaćeno 56 žena, koje su imale prevremen porođaj i 56 žena u kontrolnoj grupi koje su se porodile u terminu, starosti između 17 i 41 godine. Periodontalni pregled, uzorkovanje krvi i salive je izvršeno u prvih 48 sati po porođaju. Sekretorni status je određen metodom inhibicije hemaglutinacije. Koncentracije IL1-b i PGE2 su merene visoko senzitivnim Enzyme-linked Immunosorbent Assay (ELISA) testom. Rezultati. U grupi prevremenih porođaja bilo je 66,1% žena sa periodontitisom, a u kontrolnoj grupi 12,5% (p < 0.01). Prevremeno porođene žena, nesekretori sa periodontitisom imale su u plazmi značajno više vrednosti IL 1-b i PGE 2 u odnosu na ostale grupe (p < 0,01). U grupi prevremeno porođenih žena postojala je značajna korelacija između salivarnih i plazmatskih koncentracija PGE2 i IL1-b (R = 0.416, p = 0.017 i R = -0,592, p < 0,001, redom). Ove korelacije nisu postojale kod žena koje su imale terminski porođaj. Zaključak. Naši rezultati podržavaju hipotezu da su sekretorni status i periodontitis, bar delimično, odgovorni za patogenezu preterminskog porođaja. Verovatnoća negativnog uticaja nesekretornog statusa se ne sme ignorisati. Ovi zaključci ukazuju na potrebu za dodatnim istraživanjima porođaja.",
publisher = "Beograd : Vojnomedicinska akademija - Institut za naučne informacije",
journal = "Vojnosanitetski pregled",
title = "Salivary and plasma inflammatory mediators and secretory status in preterm delivery women with periodontitis - a cross sectional study, Salivarni i inflamatorni medijatori plazme i sekretorni status prevremeno porođenih žena sa periodontitisom – studija preseka",
volume = "77",
number = "3",
pages = "247-255",
doi = "10.2298/VSP171106066N"
}

Nikolić, L., Čakić, S., Perunović, N., Čolak, E., Kotur-Stevuljević, J., Janković, S., Đurić, M.,& Plećaš, D.. (2020). Salivary and plasma inflammatory mediators and secretory status in preterm delivery women with periodontitis - a cross sectional study. in Vojnosanitetski pregled
Beograd : Vojnomedicinska akademija - Institut za naučne informacije., 77(3), 247-255.
https://doi.org/10.2298/VSP171106066N

Nikolić L, Čakić S, Perunović N, Čolak E, Kotur-Stevuljević J, Janković S, Đurić M, Plećaš D. Salivary and plasma inflammatory mediators and secretory status in preterm delivery women with periodontitis - a cross sectional study. in Vojnosanitetski pregled. 2020;77(3):247-255.
doi:10.2298/VSP171106066N .

Nikolić, Ljubinka, Čakić, Saša, Perunović, Neda, Čolak, Emina, Kotur-Stevuljević, Jelena, Janković, Saša, Đurić, Milanko, Plećaš, Darko, "Salivary and plasma inflammatory mediators and secretory status in preterm delivery women with periodontitis - a cross sectional study" in Vojnosanitetski pregled, 77, no. 3 (2020):247-255,
https://doi.org/10.2298/VSP171106066N . .

TY  - JOUR
AU  - Čolak, Emina
AU  - Zorić, Lepša
AU  - Radosavljević, Aleksandra
AU  - Ignjatović, Svetlana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3157
AB  - Purpose: Age-related macular degeneration (AMD) is the leading cause of the irreversible central visual loss among the elderly in the developed countries. Iron is considered a potent generator of the oxidative damage whose levels increase with age, potentially exacerbating the age-related diseases. The aim of this study was to assess the serum values of iron, and iron-binding proteins (transferrin, ferritin, and haptoglobin) in patients with AMD along with the parameters of the antioxidant defense: superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase, and total antioxidant status (TAS), in order to analyze the possible impact of iron and iron-binding proteins to the development of oxidative stress in AMD patients, and the association of the selected parameters with the AMD. In addition, the aim was to examine the gender differences and calculate the cutoff points of tested parameters that could be associated with AMD.Material and methods: A cross-sectional study included 55 AMD patients aged 71.77.36 years and 65 aged-matched control subjects aged 70.256.46years.Results: Significantly lower ferritin (P=0.025), SOD (P=0.026), GPx (P=0.019), and TAS (P lt 0.004) values were found in patients with AMD compared to the controls (P lt 0.05). Significant association of GPx  lt  27U/gHb (odds ratio [OR]: 1.13; 95% confidence interval [CI] 0.78-2.10; P=0.049), TAS  lt  1.25mmol/L (OR: 5.77; 95% CI 0.98-367.0; P lt 0.000), ferritin  lt  84.8pg/mL (OR: 2.52; 95% CI 1.37-4.62; P=0.002), and haptoglobin lt 1.51g/L (OR: 1.94; 95% CI 1.05-3.56; P=0.031) was found with the AMD. According to receiver operating characteristic curve analysis, ferritin concentration  lt 84.8pg/L, GPx  lt  27U/gHb, and TAS  lt  1.25mmol/L have sufficient predictive ability for AMD.Conclusion: Significantly reduced capacity of the antioxidant defense system and iron-binding storage proteins (ferritin) found in AMD could have an important role in the development of increase oxidative stress in AMD patients.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Current Eye Research
T1  - The Association of Serum Iron-Binding Proteins and the Antioxidant Parameter Levels in Age-Related Macular Degeneration
VL  - 43
IS  - 5
SP  - 659
EP  - 665
DO  - 10.1080/02713683.2018.1437452
ER  - 

@article{
author = "Čolak, Emina and Zorić, Lepša and Radosavljević, Aleksandra and Ignjatović, Svetlana",
year = "2018",
abstract = "Purpose: Age-related macular degeneration (AMD) is the leading cause of the irreversible central visual loss among the elderly in the developed countries. Iron is considered a potent generator of the oxidative damage whose levels increase with age, potentially exacerbating the age-related diseases. The aim of this study was to assess the serum values of iron, and iron-binding proteins (transferrin, ferritin, and haptoglobin) in patients with AMD along with the parameters of the antioxidant defense: superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase, and total antioxidant status (TAS), in order to analyze the possible impact of iron and iron-binding proteins to the development of oxidative stress in AMD patients, and the association of the selected parameters with the AMD. In addition, the aim was to examine the gender differences and calculate the cutoff points of tested parameters that could be associated with AMD.Material and methods: A cross-sectional study included 55 AMD patients aged 71.77.36 years and 65 aged-matched control subjects aged 70.256.46years.Results: Significantly lower ferritin (P=0.025), SOD (P=0.026), GPx (P=0.019), and TAS (P lt 0.004) values were found in patients with AMD compared to the controls (P lt 0.05). Significant association of GPx  lt  27U/gHb (odds ratio [OR]: 1.13; 95% confidence interval [CI] 0.78-2.10; P=0.049), TAS  lt  1.25mmol/L (OR: 5.77; 95% CI 0.98-367.0; P lt 0.000), ferritin  lt  84.8pg/mL (OR: 2.52; 95% CI 1.37-4.62; P=0.002), and haptoglobin lt 1.51g/L (OR: 1.94; 95% CI 1.05-3.56; P=0.031) was found with the AMD. According to receiver operating characteristic curve analysis, ferritin concentration  lt 84.8pg/L, GPx  lt  27U/gHb, and TAS  lt  1.25mmol/L have sufficient predictive ability for AMD.Conclusion: Significantly reduced capacity of the antioxidant defense system and iron-binding storage proteins (ferritin) found in AMD could have an important role in the development of increase oxidative stress in AMD patients.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Current Eye Research",
title = "The Association of Serum Iron-Binding Proteins and the Antioxidant Parameter Levels in Age-Related Macular Degeneration",
volume = "43",
number = "5",
pages = "659-665",
doi = "10.1080/02713683.2018.1437452"
}

Čolak, E., Zorić, L., Radosavljević, A.,& Ignjatović, S.. (2018). The Association of Serum Iron-Binding Proteins and the Antioxidant Parameter Levels in Age-Related Macular Degeneration. in Current Eye Research
Taylor & Francis Inc, Philadelphia., 43(5), 659-665.
https://doi.org/10.1080/02713683.2018.1437452

Čolak E, Zorić L, Radosavljević A, Ignjatović S. The Association of Serum Iron-Binding Proteins and the Antioxidant Parameter Levels in Age-Related Macular Degeneration. in Current Eye Research. 2018;43(5):659-665.
doi:10.1080/02713683.2018.1437452 .

Čolak, Emina, Zorić, Lepša, Radosavljević, Aleksandra, Ignjatović, Svetlana, "The Association of Serum Iron-Binding Proteins and the Antioxidant Parameter Levels in Age-Related Macular Degeneration" in Current Eye Research, 43, no. 5 (2018):659-665,
https://doi.org/10.1080/02713683.2018.1437452 . .