TY  - JOUR
AU  - Savić, G.
AU  - Zečević, Mira
AU  - Jocić, B.
AU  - Živanović, Lj.
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/978
PB  - Vieweg, Wiesbaden
T2  - Chromatographia
T1  - Validation of an HPLC method for the determination of valclecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers (vol 66, pg 29, 2007)
VL  - 66
IS  - 3-4
SP  - 297
EP  - 297
DO  - 10.1365/s10337-007-0328-1
ER  - 

@article{
author = "Savić, G. and Zečević, Mira and Jocić, B. and Živanović, Lj.",
year = "2007",
publisher = "Vieweg, Wiesbaden",
journal = "Chromatographia",
title = "Validation of an HPLC method for the determination of valclecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers (vol 66, pg 29, 2007)",
volume = "66",
number = "3-4",
pages = "297-297",
doi = "10.1365/s10337-007-0328-1"
}

Savić, G., Zečević, M., Jocić, B.,& Živanović, Lj.. (2007). Validation of an HPLC method for the determination of valclecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers (vol 66, pg 29, 2007). in Chromatographia
Vieweg, Wiesbaden., 66(3-4), 297-297.
https://doi.org/10.1365/s10337-007-0328-1

Savić G, Zečević M, Jocić B, Živanović L. Validation of an HPLC method for the determination of valclecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers (vol 66, pg 29, 2007). in Chromatographia. 2007;66(3-4):297-297.
doi:10.1365/s10337-007-0328-1 .

Savić, G., Zečević, Mira, Jocić, B., Živanović, Lj., "Validation of an HPLC method for the determination of valclecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers (vol 66, pg 29, 2007)" in Chromatographia, 66, no. 3-4 (2007):297-297,
https://doi.org/10.1365/s10337-007-0328-1 . .

TY  - JOUR
AU  - Savić, G.
AU  - Zečević, Mira
AU  - Jocić, B.
AU  - Živanović, Lj.
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/975
AB  - An HPLC method has been developed for the separation of valdecoxib and a degradation product consisting of alpha and beta-N-lactosyl sulfonamide, i.e. alpha and beta anomers (SC-77852). Best results were achieved with a Chromolith Performance RP-18e column (100 mm x 4.6 mm), macropore size 2 pm, mesopore size 13 nm, with an eluent of methanol:water containing a 1% solution of TEA (36:64 v/v), pH 7.4 (adjusted with 85% orthophosphoric acid), at 22 degrees C. Detection was at 220 nm. The method was validated for its selectivity, linearity, precision (repeatability) and robustness. Quantitation and detection limits were determined for both valdecoxib and SC-77852. Method robustness was further evaluated by performing 2 3 full factorial design experiments. The final step, optimisation of the variables, was performed using response surface design. The validated method was used for assay of valdecoxib and SC77852 in Bextra((R)) film-coated tablets.
PB  - Vieweg, Wiesbaden
T2  - Chromatographia
T1  - Validation of an HPLC method for the determination of valdecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers
VL  - 66
IS  - 1-2
SP  - 29
EP  - 35
DO  - 10.1365/s10337-007-0276-9
ER  - 

@article{
author = "Savić, G. and Zečević, Mira and Jocić, B. and Živanović, Lj.",
year = "2007",
abstract = "An HPLC method has been developed for the separation of valdecoxib and a degradation product consisting of alpha and beta-N-lactosyl sulfonamide, i.e. alpha and beta anomers (SC-77852). Best results were achieved with a Chromolith Performance RP-18e column (100 mm x 4.6 mm), macropore size 2 pm, mesopore size 13 nm, with an eluent of methanol:water containing a 1% solution of TEA (36:64 v/v), pH 7.4 (adjusted with 85% orthophosphoric acid), at 22 degrees C. Detection was at 220 nm. The method was validated for its selectivity, linearity, precision (repeatability) and robustness. Quantitation and detection limits were determined for both valdecoxib and SC-77852. Method robustness was further evaluated by performing 2 3 full factorial design experiments. The final step, optimisation of the variables, was performed using response surface design. The validated method was used for assay of valdecoxib and SC77852 in Bextra((R)) film-coated tablets.",
publisher = "Vieweg, Wiesbaden",
journal = "Chromatographia",
title = "Validation of an HPLC method for the determination of valdecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers",
volume = "66",
number = "1-2",
pages = "29-35",
doi = "10.1365/s10337-007-0276-9"
}

Savić, G., Zečević, M., Jocić, B.,& Živanović, Lj.. (2007). Validation of an HPLC method for the determination of valdecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers. in Chromatographia
Vieweg, Wiesbaden., 66(1-2), 29-35.
https://doi.org/10.1365/s10337-007-0276-9

Savić G, Zečević M, Jocić B, Živanović L. Validation of an HPLC method for the determination of valdecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers. in Chromatographia. 2007;66(1-2):29-35.
doi:10.1365/s10337-007-0276-9 .

Savić, G., Zečević, Mira, Jocić, B., Živanović, Lj., "Validation of an HPLC method for the determination of valdecoxib and its degradation product: a mixture of alpha- and beta-n-lactosyl sulfonamide anomers" in Chromatographia, 66, no. 1-2 (2007):29-35,
https://doi.org/10.1365/s10337-007-0276-9 . .

TY  - JOUR
AU  - Zečević, Mira
AU  - Savić, G
AU  - Živanović, L
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/775
AB  - A reversed-phase liquid chromatography method has been developed for the separation of valdecoxib and impurity SC-77852. The best results were achieved using a mobile phase-methanol: 1% water solution TEA (52 : 48 v/v), pH 7.35 (adjusted with 85% orthophosphoric acid), column temperature 24 degrees C. Separation was carried out on XTerra (TM) RP18 (150mm x 4,6 mm), particle size 5 mu m, flow rate 1ml/min, using detection on 220 nm. The method was statistically validated for its selectivity, linearity, precision (repeatability), and robustness. Quantitation and detection limits were determined for both valdecoxib and SC-77852. Method robustness was further evaluated by performing full factorial design experiment. Validated method was used for assay of valdecoxib and SC-77852 in Bextra (R) film-coated tablets.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Analytical Letters
T1  - Development and validation of liquid chromatography method for the separation of valdecoxib and its SC-77852 impurity
VL  - 39
IS  - 9
SP  - 1875
EP  - 1890
DO  - 10.1080/00032710600721605
ER  - 

@article{
author = "Zečević, Mira and Savić, G and Živanović, L",
year = "2006",
abstract = "A reversed-phase liquid chromatography method has been developed for the separation of valdecoxib and impurity SC-77852. The best results were achieved using a mobile phase-methanol: 1% water solution TEA (52 : 48 v/v), pH 7.35 (adjusted with 85% orthophosphoric acid), column temperature 24 degrees C. Separation was carried out on XTerra (TM) RP18 (150mm x 4,6 mm), particle size 5 mu m, flow rate 1ml/min, using detection on 220 nm. The method was statistically validated for its selectivity, linearity, precision (repeatability), and robustness. Quantitation and detection limits were determined for both valdecoxib and SC-77852. Method robustness was further evaluated by performing full factorial design experiment. Validated method was used for assay of valdecoxib and SC-77852 in Bextra (R) film-coated tablets.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Analytical Letters",
title = "Development and validation of liquid chromatography method for the separation of valdecoxib and its SC-77852 impurity",
volume = "39",
number = "9",
pages = "1875-1890",
doi = "10.1080/00032710600721605"
}

Zečević, M., Savić, G.,& Živanović, L.. (2006). Development and validation of liquid chromatography method for the separation of valdecoxib and its SC-77852 impurity. in Analytical Letters
Taylor & Francis Inc, Philadelphia., 39(9), 1875-1890.
https://doi.org/10.1080/00032710600721605

Zečević M, Savić G, Živanović L. Development and validation of liquid chromatography method for the separation of valdecoxib and its SC-77852 impurity. in Analytical Letters. 2006;39(9):1875-1890.
doi:10.1080/00032710600721605 .

Zečević, Mira, Savić, G, Živanović, L, "Development and validation of liquid chromatography method for the separation of valdecoxib and its SC-77852 impurity" in Analytical Letters, 39, no. 9 (2006):1875-1890,
https://doi.org/10.1080/00032710600721605 . .