TY  - JOUR
AU  - Kundaković, Tatjana
AU  - Fokialakis, N.
AU  - Kovačević, Nada
AU  - Chinou, I.
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/919
AB  - The composition of the essential oils of Achillea lingulata and A. umbellata were analysed by GC and GCMS. Among the determined constituents, borneol, bornyl acetate, camphor, alpha- and beta-thujone, and 1,8-cineol were found as the main components. Copyright
PB  - John Wiley & Sons Ltd, Chichester
T2  - Flavour and Fragrance Journal
T1  - Essential oil composition of Achillea lingulata and A-umbellata
VL  - 22
IS  - 3
SP  - 184
EP  - 187
DO  - 10.1002/ffj.1778
ER  - 

@article{
author = "Kundaković, Tatjana and Fokialakis, N. and Kovačević, Nada and Chinou, I.",
year = "2007",
abstract = "The composition of the essential oils of Achillea lingulata and A. umbellata were analysed by GC and GCMS. Among the determined constituents, borneol, bornyl acetate, camphor, alpha- and beta-thujone, and 1,8-cineol were found as the main components. Copyright",
publisher = "John Wiley & Sons Ltd, Chichester",
journal = "Flavour and Fragrance Journal",
title = "Essential oil composition of Achillea lingulata and A-umbellata",
volume = "22",
number = "3",
pages = "184-187",
doi = "10.1002/ffj.1778"
}

Kundaković, T., Fokialakis, N., Kovačević, N.,& Chinou, I.. (2007). Essential oil composition of Achillea lingulata and A-umbellata. in Flavour and Fragrance Journal
John Wiley & Sons Ltd, Chichester., 22(3), 184-187.
https://doi.org/10.1002/ffj.1778

Kundaković T, Fokialakis N, Kovačević N, Chinou I. Essential oil composition of Achillea lingulata and A-umbellata. in Flavour and Fragrance Journal. 2007;22(3):184-187.
doi:10.1002/ffj.1778 .

Kundaković, Tatjana, Fokialakis, N., Kovačević, Nada, Chinou, I., "Essential oil composition of Achillea lingulata and A-umbellata" in Flavour and Fragrance Journal, 22, no. 3 (2007):184-187,
https://doi.org/10.1002/ffj.1778 . .

TY  - JOUR
AU  - Kundaković, Tatjana
AU  - Fokialakis, N.
AU  - Dobrić, Silva
AU  - Pratsinis, H
AU  - Kletsas, D
AU  - Kovačević, Nada
AU  - Chinou, I
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/849
AB  - The root extracts of Onosma leptanhtha were evaluated for their anti-iflammatory and cytotoxic activities. The cyclohexane extract, which appeared as the most active in both assays, has been further subjected to bioassay-directed fractionation to afford the naphthazarine derivatives: beta,beta-dimethylacrylshikonin (1), isovalerylshikonin (2) and acetylshikonin (3). The evaluation of the anti-inflammatory activity was performed on carrageenan-induced rat paw edema test. All the tested compounds proved to be active, while compound 3 showed the best anti-inflammatory effect. In addition, the cytotoxic activity of the extracts and isolated compounds, was also assayed against L1210 murine lymphoblastic leukemia cell line, and human fibrosarcoma HT-1080 cells. Compound I exhibited remarkable cytotoxic activity (390nM for L1210 cells), which is superior to that of shikonin, which was used as control.
PB  - Elsevier Gmbh, Urban & Fischer Verlag, Jena
T2  - Phytomedicine
T1  - Evaluation of the anti-inflammatory and cytotoxic activities of naphthazarine derivatives from Onosma lentantha
VL  - 13
IS  - 4
SP  - 290
EP  - 294
DO  - 10.1016/j.phymed.2004.10.009
ER  - 

@article{
author = "Kundaković, Tatjana and Fokialakis, N. and Dobrić, Silva and Pratsinis, H and Kletsas, D and Kovačević, Nada and Chinou, I",
year = "2006",
abstract = "The root extracts of Onosma leptanhtha were evaluated for their anti-iflammatory and cytotoxic activities. The cyclohexane extract, which appeared as the most active in both assays, has been further subjected to bioassay-directed fractionation to afford the naphthazarine derivatives: beta,beta-dimethylacrylshikonin (1), isovalerylshikonin (2) and acetylshikonin (3). The evaluation of the anti-inflammatory activity was performed on carrageenan-induced rat paw edema test. All the tested compounds proved to be active, while compound 3 showed the best anti-inflammatory effect. In addition, the cytotoxic activity of the extracts and isolated compounds, was also assayed against L1210 murine lymphoblastic leukemia cell line, and human fibrosarcoma HT-1080 cells. Compound I exhibited remarkable cytotoxic activity (390nM for L1210 cells), which is superior to that of shikonin, which was used as control.",
publisher = "Elsevier Gmbh, Urban & Fischer Verlag, Jena",
journal = "Phytomedicine",
title = "Evaluation of the anti-inflammatory and cytotoxic activities of naphthazarine derivatives from Onosma lentantha",
volume = "13",
number = "4",
pages = "290-294",
doi = "10.1016/j.phymed.2004.10.009"
}

Kundaković, T., Fokialakis, N., Dobrić, S., Pratsinis, H., Kletsas, D., Kovačević, N.,& Chinou, I.. (2006). Evaluation of the anti-inflammatory and cytotoxic activities of naphthazarine derivatives from Onosma lentantha. in Phytomedicine
Elsevier Gmbh, Urban & Fischer Verlag, Jena., 13(4), 290-294.
https://doi.org/10.1016/j.phymed.2004.10.009

Kundaković T, Fokialakis N, Dobrić S, Pratsinis H, Kletsas D, Kovačević N, Chinou I. Evaluation of the anti-inflammatory and cytotoxic activities of naphthazarine derivatives from Onosma lentantha. in Phytomedicine. 2006;13(4):290-294.
doi:10.1016/j.phymed.2004.10.009 .

Kundaković, Tatjana, Fokialakis, N., Dobrić, Silva, Pratsinis, H, Kletsas, D, Kovačević, Nada, Chinou, I, "Evaluation of the anti-inflammatory and cytotoxic activities of naphthazarine derivatives from Onosma lentantha" in Phytomedicine, 13, no. 4 (2006):290-294,
https://doi.org/10.1016/j.phymed.2004.10.009 . .

TY  - JOUR
AU  - Kundaković, Tatjana
AU  - Fokialakis, N.
AU  - Magiatis, P
AU  - Kovačević, Nada
AU  - Chinou, L
PY  - 2004
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/503
AB  - Investigation of the aerial parts of Achillea alexandri-regis led to the identification of 19 chemical constituents: twelve 3-O-fatty acid esters of triterpene alcohols arnidiol (1-4), maniladiol (5-8) and 16beta-hydroxy-lupeol (9-12), alpha-amyrin, beta-amyrin, beta-sitosterol, 3,4-O-dicaffeoyl quinic acid, cinnamic acid, pinoresinol-beta-D-glucoside and rutin. Among them, compounds 3, 4, 8, 11 and 12 are new natural products. The structures of all compounds have been elucidated on the basis of their spectral and chemical data.
PB  - Pharmaceutical Soc Japan, Tokyo
T2  - Chemical & Pharmaceutical Bulletin
T1  - Triterpenic derivatives of Achillea alexandri-regis Bornm. & Rudski
VL  - 52
IS  - 12
SP  - 1462
EP  - 1465
DO  - 10.1248/cpb.52.1462
ER  - 

@article{
author = "Kundaković, Tatjana and Fokialakis, N. and Magiatis, P and Kovačević, Nada and Chinou, L",
year = "2004",
abstract = "Investigation of the aerial parts of Achillea alexandri-regis led to the identification of 19 chemical constituents: twelve 3-O-fatty acid esters of triterpene alcohols arnidiol (1-4), maniladiol (5-8) and 16beta-hydroxy-lupeol (9-12), alpha-amyrin, beta-amyrin, beta-sitosterol, 3,4-O-dicaffeoyl quinic acid, cinnamic acid, pinoresinol-beta-D-glucoside and rutin. Among them, compounds 3, 4, 8, 11 and 12 are new natural products. The structures of all compounds have been elucidated on the basis of their spectral and chemical data.",
publisher = "Pharmaceutical Soc Japan, Tokyo",
journal = "Chemical & Pharmaceutical Bulletin",
title = "Triterpenic derivatives of Achillea alexandri-regis Bornm. & Rudski",
volume = "52",
number = "12",
pages = "1462-1465",
doi = "10.1248/cpb.52.1462"
}

Kundaković, T., Fokialakis, N., Magiatis, P., Kovačević, N.,& Chinou, L.. (2004). Triterpenic derivatives of Achillea alexandri-regis Bornm. & Rudski. in Chemical & Pharmaceutical Bulletin
Pharmaceutical Soc Japan, Tokyo., 52(12), 1462-1465.
https://doi.org/10.1248/cpb.52.1462

Kundaković T, Fokialakis N, Magiatis P, Kovačević N, Chinou L. Triterpenic derivatives of Achillea alexandri-regis Bornm. & Rudski. in Chemical & Pharmaceutical Bulletin. 2004;52(12):1462-1465.
doi:10.1248/cpb.52.1462 .

Kundaković, Tatjana, Fokialakis, N., Magiatis, P, Kovačević, Nada, Chinou, L, "Triterpenic derivatives of Achillea alexandri-regis Bornm. & Rudski" in Chemical & Pharmaceutical Bulletin, 52, no. 12 (2004):1462-1465,
https://doi.org/10.1248/cpb.52.1462 . .