TY  - JOUR
AU  - Tomić, Ana
AU  - Božin, Biljana
AU  - Samojlik, Isidora
AU  - Milenković, Marina
AU  - Mimica-Dukić, Neda
AU  - Petrović, Silvana
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5235
AB  - The effects of essential oils isolated from mature fruits of Athamanta turbith ssp. hungarica (Borbás) Tutin
and A. turbith ssp. haynaldii (Borbás & Uechtr.) Tutin (Umbelliferae) on some liver biochemical parameters
in mice intoxicated with carbon tetrachloride were investigated. Pretreatment with both essential oils extenuated
the effects caused by carbon tetrachloride. In order to investigate in vitro antioxidant properties of the
oils, three methods were applied: scavenging of both 2,2-diphenyl-1-picrylhydrazyl (DPPH) and OH radicals,
as well as a test of inhibition of Fe2+/ascorbic-induced lipid peroxidation. Investigated essential oils exhibited
modest antioxidant capacity. Therefore, their infl uence on biochemical parameters in intoxicated animals might
be linked to the inhibition of enzymes (cytochrome P450 2E1) involved in metabolic activation of halomethanes.
PB  - John Wiley & Sons, Ltd.
T2  - Phytotherapy Research
T1  - Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties
VL  - 24
IS  - 5
SP  - 787
EP  - 790
DO  - 10.1002/ptr.3036
ER  - 

@article{
author = "Tomić, Ana and Božin, Biljana and Samojlik, Isidora and Milenković, Marina and Mimica-Dukić, Neda and Petrović, Silvana",
year = "2010",
abstract = "The effects of essential oils isolated from mature fruits of Athamanta turbith ssp. hungarica (Borbás) Tutin
and A. turbith ssp. haynaldii (Borbás & Uechtr.) Tutin (Umbelliferae) on some liver biochemical parameters
in mice intoxicated with carbon tetrachloride were investigated. Pretreatment with both essential oils extenuated
the effects caused by carbon tetrachloride. In order to investigate in vitro antioxidant properties of the
oils, three methods were applied: scavenging of both 2,2-diphenyl-1-picrylhydrazyl (DPPH) and OH radicals,
as well as a test of inhibition of Fe2+/ascorbic-induced lipid peroxidation. Investigated essential oils exhibited
modest antioxidant capacity. Therefore, their infl uence on biochemical parameters in intoxicated animals might
be linked to the inhibition of enzymes (cytochrome P450 2E1) involved in metabolic activation of halomethanes.",
publisher = "John Wiley & Sons, Ltd.",
journal = "Phytotherapy Research",
title = "Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties",
volume = "24",
number = "5",
pages = "787-790",
doi = "10.1002/ptr.3036"
}

Tomić, A., Božin, B., Samojlik, I., Milenković, M., Mimica-Dukić, N.,& Petrović, S.. (2010). Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties. in Phytotherapy Research
John Wiley & Sons, Ltd.., 24(5), 787-790.
https://doi.org/10.1002/ptr.3036

Tomić A, Božin B, Samojlik I, Milenković M, Mimica-Dukić N, Petrović S. Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties. in Phytotherapy Research. 2010;24(5):787-790.
doi:10.1002/ptr.3036 .

Tomić, Ana, Božin, Biljana, Samojlik, Isidora, Milenković, Marina, Mimica-Dukić, Neda, Petrović, Silvana, "Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties" in Phytotherapy Research, 24, no. 5 (2010):787-790,
https://doi.org/10.1002/ptr.3036 . .

TY  - JOUR
AU  - Tomić, Ana
AU  - Petrović, Silvana
AU  - Drobac, Milica
AU  - Trajkovski, Bojana
AU  - Milenković, Marina
AU  - Božić, Dragana
AU  - Niketić, Marjan
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1273
AB  - The methanol extracts of fruits and leaves of Athamanta turbith subsp. hungarica (Borbas) Tutin (Umbelliferae) and A. turbith subsp. haynaldii (Borbas & Uechtr.) Tutin were analyzed for their antimicrobial and antioxidant properties. Phenolic compounds (flavonoids and phenolic acids) of the extracts were examined using HPLC. All the extracts were characterized by the presence of caffeic acid derivates, luteolin and its glycosides, with luteolin 7-O-glucoside as one of the main compounds. Luteolin 7-O-rutinoside was detected only in A. turbith subsp. haynaldii extracts. Investigation of antimicrobial activity was performed against six bacteria and two fungal strains, using the agar diffusion technique and broth microdilution assay. The extracts of investigated A. turbith subspecies exerted similar antimicrobial activity, whereas the best activity was detected against Candida albicans. In order to investigate antioxidant properties, ferric ion reducing antioxidant power (FRAP), radical scavenging capacity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical (HO.), and the effect on lipid peroxidation (LP) were examined. All the examined extracts showed moderate antioxidant capacity, whereas the fruit extracts were more active than the extracts of leaves. Also, the extracts of A. turbith subsp. hungarica exerted higher antioxidant capacity than corresponding A. turbith subsp. haynaldii extracts. The relationship between estimated activity and chemical composition of the extracts is discussed.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Pharmaceutical Biology
T1  - Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies
VL  - 47
IS  - 4
SP  - 314
EP  - 319
DO  - 10.1080/13880200902748452
ER  - 

@article{
author = "Tomić, Ana and Petrović, Silvana and Drobac, Milica and Trajkovski, Bojana and Milenković, Marina and Božić, Dragana and Niketić, Marjan",
year = "2009",
abstract = "The methanol extracts of fruits and leaves of Athamanta turbith subsp. hungarica (Borbas) Tutin (Umbelliferae) and A. turbith subsp. haynaldii (Borbas & Uechtr.) Tutin were analyzed for their antimicrobial and antioxidant properties. Phenolic compounds (flavonoids and phenolic acids) of the extracts were examined using HPLC. All the extracts were characterized by the presence of caffeic acid derivates, luteolin and its glycosides, with luteolin 7-O-glucoside as one of the main compounds. Luteolin 7-O-rutinoside was detected only in A. turbith subsp. haynaldii extracts. Investigation of antimicrobial activity was performed against six bacteria and two fungal strains, using the agar diffusion technique and broth microdilution assay. The extracts of investigated A. turbith subspecies exerted similar antimicrobial activity, whereas the best activity was detected against Candida albicans. In order to investigate antioxidant properties, ferric ion reducing antioxidant power (FRAP), radical scavenging capacity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical (HO.), and the effect on lipid peroxidation (LP) were examined. All the examined extracts showed moderate antioxidant capacity, whereas the fruit extracts were more active than the extracts of leaves. Also, the extracts of A. turbith subsp. hungarica exerted higher antioxidant capacity than corresponding A. turbith subsp. haynaldii extracts. The relationship between estimated activity and chemical composition of the extracts is discussed.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Pharmaceutical Biology",
title = "Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies",
volume = "47",
number = "4",
pages = "314-319",
doi = "10.1080/13880200902748452"
}

Tomić, A., Petrović, S., Drobac, M., Trajkovski, B., Milenković, M., Božić, D.,& Niketić, M.. (2009). Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies. in Pharmaceutical Biology
Taylor & Francis Ltd, Abingdon., 47(4), 314-319.
https://doi.org/10.1080/13880200902748452

Tomić A, Petrović S, Drobac M, Trajkovski B, Milenković M, Božić D, Niketić M. Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies. in Pharmaceutical Biology. 2009;47(4):314-319.
doi:10.1080/13880200902748452 .

Tomić, Ana, Petrović, Silvana, Drobac, Milica, Trajkovski, Bojana, Milenković, Marina, Božić, Dragana, Niketić, Marjan, "Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies" in Pharmaceutical Biology, 47, no. 4 (2009):314-319,
https://doi.org/10.1080/13880200902748452 . .

TY  - JOUR
AU  - Tomić, Ana
AU  - Petrović, Silvana
AU  - Drobac, Milica
AU  - Tzakou, Olga
AU  - Couladis, Maria
AU  - Milenković, Marina
AU  - Božić, Dragana
AU  - Lakušić, Branislava
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1227
AB  - The hydrodistilled essential oils of the rhizomes of Athamanta turbith subsp. hungarica and A. turbith subsp. haynaldii were analyzed by GC-FID and GC/MS. Twenty-one compounds (99.8% of total oil) were identified in the oil from A. turbith subsp. hungarica, mid 33 components (99.9% of total oil) were identified in the oil from A. turbith subsp. haynaldii. Both oils were characterized by high amounts of phenylpropanes, with myristicin (54.2% and 22.3%, respectively) and apiole (32.6% and 48.5%, respectively) being the main components. The antimicrobial activity of the oils was determined using the agar diffusion and broth microdilution method. Investigated essential oils were the most effective against Micrococcus luteus and Klebsiella pneumoniae, and had no effect against Pseudomonas aeruginosa. As for antifungal activity, essential oils exerted similar and significant activity, but only in higher concentrations.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Essential Oil Research
T1  - Composition and Antimicrobial Activity of the Rhizome Essential Oils of Two Athamanta turbith Subspecies
VL  - 21
IS  - 3
SP  - 276
EP  - 279
DO  - 10.1080/10412905.2009.9700169
ER  - 

@article{
author = "Tomić, Ana and Petrović, Silvana and Drobac, Milica and Tzakou, Olga and Couladis, Maria and Milenković, Marina and Božić, Dragana and Lakušić, Branislava",
year = "2009",
abstract = "The hydrodistilled essential oils of the rhizomes of Athamanta turbith subsp. hungarica and A. turbith subsp. haynaldii were analyzed by GC-FID and GC/MS. Twenty-one compounds (99.8% of total oil) were identified in the oil from A. turbith subsp. hungarica, mid 33 components (99.9% of total oil) were identified in the oil from A. turbith subsp. haynaldii. Both oils were characterized by high amounts of phenylpropanes, with myristicin (54.2% and 22.3%, respectively) and apiole (32.6% and 48.5%, respectively) being the main components. The antimicrobial activity of the oils was determined using the agar diffusion and broth microdilution method. Investigated essential oils were the most effective against Micrococcus luteus and Klebsiella pneumoniae, and had no effect against Pseudomonas aeruginosa. As for antifungal activity, essential oils exerted similar and significant activity, but only in higher concentrations.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Essential Oil Research",
title = "Composition and Antimicrobial Activity of the Rhizome Essential Oils of Two Athamanta turbith Subspecies",
volume = "21",
number = "3",
pages = "276-279",
doi = "10.1080/10412905.2009.9700169"
}

Tomić, A., Petrović, S., Drobac, M., Tzakou, O., Couladis, M., Milenković, M., Božić, D.,& Lakušić, B.. (2009). Composition and Antimicrobial Activity of the Rhizome Essential Oils of Two Athamanta turbith Subspecies. in Journal of Essential Oil Research
Taylor & Francis Inc, Philadelphia., 21(3), 276-279.
https://doi.org/10.1080/10412905.2009.9700169

Tomić A, Petrović S, Drobac M, Tzakou O, Couladis M, Milenković M, Božić D, Lakušić B. Composition and Antimicrobial Activity of the Rhizome Essential Oils of Two Athamanta turbith Subspecies. in Journal of Essential Oil Research. 2009;21(3):276-279.
doi:10.1080/10412905.2009.9700169 .

Tomić, Ana, Petrović, Silvana, Drobac, Milica, Tzakou, Olga, Couladis, Maria, Milenković, Marina, Božić, Dragana, Lakušić, Branislava, "Composition and Antimicrobial Activity of the Rhizome Essential Oils of Two Athamanta turbith Subspecies" in Journal of Essential Oil Research, 21, no. 3 (2009):276-279,
https://doi.org/10.1080/10412905.2009.9700169 . .