TY  - JOUR
AU  - Milenković, Marina
AU  - Stošović, Jelena
AU  - Slavkovska, Violeta
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3146
AB  - The subject of the study was the investigation of the chemical composition and antimicrobial activity of the essential oils (EOs) isolated from Calamintha sylvatica, C. vardarensis, C. nepeta and C. glandulosa, as well as their antibacterial activity in combination with antibiotics. The quantitative and qualitative analysis of EOs was performed using the GC/FID and GC/MS methods. The antimicrobial activity of EOs against six standard bacterial strains and one strain of yeast was tested using the broth microdilution method, while the antimicrobial activity of a combination of essential oils and gentamicin/ciprofloxacin was tested by the checkerboard method. The dominant components (> 10%) of the essential oils were: cis-piperitone epoxide and menthone (C. sylvatica), pulegone and menthone (C. vardarensis), pulegone and piperitenone (C. nepeta), pulegone, piperitenone, menthone and piperitone (C. glandulosa). EOs did not exhibit significant antimicrobial activity except the essential oil of C. vardarensis which was selectively active against Staphylococcus aureus (MIC - 21.25 mu g/mL). The overall effect of essential oil-antibiotic combinations varied from synergistic (FICI  lt = 0.5) to antagonistic (FICI >= 2) depending on the bacterial strain tested.
PB  - Sage Publications Inc, Thousand Oaks
T2  - Natural Product Communications
T1  - Synergy between Essential Oils of Calamintha Species (Lamiaceae) and Antibiotics
VL  - 13
IS  - 3
SP  - 371
EP  - 374
UR  - https://hdl.handle.net/21.15107/rcub_farfar_3146
ER  - 

@article{
author = "Milenković, Marina and Stošović, Jelena and Slavkovska, Violeta",
year = "2018",
abstract = "The subject of the study was the investigation of the chemical composition and antimicrobial activity of the essential oils (EOs) isolated from Calamintha sylvatica, C. vardarensis, C. nepeta and C. glandulosa, as well as their antibacterial activity in combination with antibiotics. The quantitative and qualitative analysis of EOs was performed using the GC/FID and GC/MS methods. The antimicrobial activity of EOs against six standard bacterial strains and one strain of yeast was tested using the broth microdilution method, while the antimicrobial activity of a combination of essential oils and gentamicin/ciprofloxacin was tested by the checkerboard method. The dominant components (> 10%) of the essential oils were: cis-piperitone epoxide and menthone (C. sylvatica), pulegone and menthone (C. vardarensis), pulegone and piperitenone (C. nepeta), pulegone, piperitenone, menthone and piperitone (C. glandulosa). EOs did not exhibit significant antimicrobial activity except the essential oil of C. vardarensis which was selectively active against Staphylococcus aureus (MIC - 21.25 mu g/mL). The overall effect of essential oil-antibiotic combinations varied from synergistic (FICI  lt = 0.5) to antagonistic (FICI >= 2) depending on the bacterial strain tested.",
publisher = "Sage Publications Inc, Thousand Oaks",
journal = "Natural Product Communications",
title = "Synergy between Essential Oils of Calamintha Species (Lamiaceae) and Antibiotics",
volume = "13",
number = "3",
pages = "371-374",
url = "https://hdl.handle.net/21.15107/rcub_farfar_3146"
}

Milenković, M., Stošović, J.,& Slavkovska, V.. (2018). Synergy between Essential Oils of Calamintha Species (Lamiaceae) and Antibiotics. in Natural Product Communications
Sage Publications Inc, Thousand Oaks., 13(3), 371-374.
https://hdl.handle.net/21.15107/rcub_farfar_3146

Milenković M, Stošović J, Slavkovska V. Synergy between Essential Oils of Calamintha Species (Lamiaceae) and Antibiotics. in Natural Product Communications. 2018;13(3):371-374.
https://hdl.handle.net/21.15107/rcub_farfar_3146 .

Milenković, Marina, Stošović, Jelena, Slavkovska, Violeta, "Synergy between Essential Oils of Calamintha Species (Lamiaceae) and Antibiotics" in Natural Product Communications, 13, no. 3 (2018):371-374,
https://hdl.handle.net/21.15107/rcub_farfar_3146 .