TY  - JOUR
AU  - Ilić, Violeta
AU  - Bogićević, Dragana
AU  - Miljković, Branislava
AU  - Vezmar-Kovačević, Sandra
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3049
AB  - Background and Aim: Adverse effects are common in children treated with antiepileptic medications and may affect parental beliefs about treatment. The aim of the study was to investigate the relationship between adverse effects and parental beliefs about antiepileptic drugs used for the treatment of their children. Methods: The study was performed at the University Children's Hospital, Belgrade, Serbia from 2013-2015. Parents of children treated with valproic acid, carbamazepine or lamotrigine, were eligible. They were asked to fill in the Beliefs about Medications Questionnaire (BMQ) and The Liverpool Adverse Events Profile (LAEP). Results: Parents of 127 children (average age 9.88 +/- 4.16 years) of whom 111 had epilepsy (67 generalized, 44 focal) and 16 with febrile seizures participated in the study. Nervousness and/or agitation, weight gain, restlessness, headache, difficulty in concentrating, feeling of aggression and upset stomach were most frequent adverse effects, reported in 37% of the population. BMQ-specific necessity scores significantly correlated with parental education; parents with elementary school showed lower scores than those with higher education. The presence of difficulty in concentrating of their child was associated with higher BMQ concern scores (20.73 +/- 4.25 vs. 18.99 +/- 3.60, p = 0.043) as well as necessity scores (18.42 +/- 3.31 vs. 16.40 +/- 2.73, p = 0.017). Higher scores of BMQ-general overuse were reported in the presence of a headache (8.79 +/- 2.81 vs. 7.64 +/- 2.72, p = 0.027). Conclusions: The main finding of our study is that parental beliefs about antiepileptic drugs were associated with the presence of adverse effects. Understanding this relationship could allow physicians and pharmacists to structure better educational programs for parents of children treated with antiepileptic drugs. Education should be more focused towards understanding the adverse effects of antiepileptics which could alleviate parental concerns and strengthen their beliefs about the necessity of medication use in their children.
PB  - MDPI, Basel
T2  - Medicina-Lithuania
T1  - Association between Adverse Effects and Parental Beliefs about Antiepileptic Medicines
VL  - 54
IS  - 4
DO  - 10.3390/medicina54040060
ER  - 

@article{
author = "Ilić, Violeta and Bogićević, Dragana and Miljković, Branislava and Vezmar-Kovačević, Sandra",
year = "2018",
abstract = "Background and Aim: Adverse effects are common in children treated with antiepileptic medications and may affect parental beliefs about treatment. The aim of the study was to investigate the relationship between adverse effects and parental beliefs about antiepileptic drugs used for the treatment of their children. Methods: The study was performed at the University Children's Hospital, Belgrade, Serbia from 2013-2015. Parents of children treated with valproic acid, carbamazepine or lamotrigine, were eligible. They were asked to fill in the Beliefs about Medications Questionnaire (BMQ) and The Liverpool Adverse Events Profile (LAEP). Results: Parents of 127 children (average age 9.88 +/- 4.16 years) of whom 111 had epilepsy (67 generalized, 44 focal) and 16 with febrile seizures participated in the study. Nervousness and/or agitation, weight gain, restlessness, headache, difficulty in concentrating, feeling of aggression and upset stomach were most frequent adverse effects, reported in 37% of the population. BMQ-specific necessity scores significantly correlated with parental education; parents with elementary school showed lower scores than those with higher education. The presence of difficulty in concentrating of their child was associated with higher BMQ concern scores (20.73 +/- 4.25 vs. 18.99 +/- 3.60, p = 0.043) as well as necessity scores (18.42 +/- 3.31 vs. 16.40 +/- 2.73, p = 0.017). Higher scores of BMQ-general overuse were reported in the presence of a headache (8.79 +/- 2.81 vs. 7.64 +/- 2.72, p = 0.027). Conclusions: The main finding of our study is that parental beliefs about antiepileptic drugs were associated with the presence of adverse effects. Understanding this relationship could allow physicians and pharmacists to structure better educational programs for parents of children treated with antiepileptic drugs. Education should be more focused towards understanding the adverse effects of antiepileptics which could alleviate parental concerns and strengthen their beliefs about the necessity of medication use in their children.",
publisher = "MDPI, Basel",
journal = "Medicina-Lithuania",
title = "Association between Adverse Effects and Parental Beliefs about Antiepileptic Medicines",
volume = "54",
number = "4",
doi = "10.3390/medicina54040060"
}

Ilić, V., Bogićević, D., Miljković, B.,& Vezmar-Kovačević, S.. (2018). Association between Adverse Effects and Parental Beliefs about Antiepileptic Medicines. in Medicina-Lithuania
MDPI, Basel., 54(4).
https://doi.org/10.3390/medicina54040060

Ilić V, Bogićević D, Miljković B, Vezmar-Kovačević S. Association between Adverse Effects and Parental Beliefs about Antiepileptic Medicines. in Medicina-Lithuania. 2018;54(4).
doi:10.3390/medicina54040060 .

Ilić, Violeta, Bogićević, Dragana, Miljković, Branislava, Vezmar-Kovačević, Sandra, "Association between Adverse Effects and Parental Beliefs about Antiepileptic Medicines" in Medicina-Lithuania, 54, no. 4 (2018),
https://doi.org/10.3390/medicina54040060 . .