TY  - JOUR
AU  - Pirković, Andrea
AU  - Dekanski, Dragana
AU  - Živković, Lada
AU  - Milanović-Čabarkapa, Mirjana
AU  - Bajić, Vladan
AU  - Topalović, Dijana
AU  - Giampieri, Francesca
AU  - Gasparrini, Massimiliano
AU  - Battino, Maurizio
AU  - Potparević, Biljana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2822
AB  - The CaNa(2)EDTA chelation therapy is often practiced with antioxidant supplementation. Dry olive leaf extract (DOLE) is natural product with antioxidant and DNA protective properties. The effects of DOLE on the levels of DNA damage were investigated ex vivo in peripheral blood lymphocytes (PBLs) of 19 workers occupationally exposed to lead (Pb), before and after CaNa(2)EDTA chelation therapy. POLE demonstrated pronounced radical scavenging activity in concentrations >= 1 mg/mL, and showed no genotoxicity per se, in concentrations 0.125-1 mg/mL. The level of DNA damage in PBLs of workers before chelation therapy was elevated (24.21 +/- 14.26) compared to controls (6.0 +/- 3.37). The incubation of PBLs before chelation therapy with selected concentration of DOLE lead to a severe increase of DNA damage (64.03 +/- 20.96), exhibiting prooxidant rather than antioxidant effect. After the five-day CaNa2EDTA chelation regimen, DNA damage in PBLs of workers decreased (8.26 +/- 4.62) significantly compared to baseline. Treatment of PBLs with DOLE after chelation, again produced high level of damage (41.82 +/- 23.17) and the acute prooxidant effects of DOLE remained, but, DNA damage was less severe than before chelation. The DOLE exhibits prooxidant effect in presence of Pb in lymphocytes of exposed workers, and its effect is less pronounced following the removal of Pb after standard chelation therapy.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Food and Chemical Toxicology
T1  - Unexpected effect of dry olive leaf extract on the level of DNA damage in lymphocytes of lead intoxicated workers, before and after CaNa(2)EDTA chelation therapy
VL  - 106
SP  - 616
EP  - 623
DO  - 10.1016/j.fct.2016.12.023
ER  - 

@article{
author = "Pirković, Andrea and Dekanski, Dragana and Živković, Lada and Milanović-Čabarkapa, Mirjana and Bajić, Vladan and Topalović, Dijana and Giampieri, Francesca and Gasparrini, Massimiliano and Battino, Maurizio and Potparević, Biljana",
year = "2017",
abstract = "The CaNa(2)EDTA chelation therapy is often practiced with antioxidant supplementation. Dry olive leaf extract (DOLE) is natural product with antioxidant and DNA protective properties. The effects of DOLE on the levels of DNA damage were investigated ex vivo in peripheral blood lymphocytes (PBLs) of 19 workers occupationally exposed to lead (Pb), before and after CaNa(2)EDTA chelation therapy. POLE demonstrated pronounced radical scavenging activity in concentrations >= 1 mg/mL, and showed no genotoxicity per se, in concentrations 0.125-1 mg/mL. The level of DNA damage in PBLs of workers before chelation therapy was elevated (24.21 +/- 14.26) compared to controls (6.0 +/- 3.37). The incubation of PBLs before chelation therapy with selected concentration of DOLE lead to a severe increase of DNA damage (64.03 +/- 20.96), exhibiting prooxidant rather than antioxidant effect. After the five-day CaNa2EDTA chelation regimen, DNA damage in PBLs of workers decreased (8.26 +/- 4.62) significantly compared to baseline. Treatment of PBLs with DOLE after chelation, again produced high level of damage (41.82 +/- 23.17) and the acute prooxidant effects of DOLE remained, but, DNA damage was less severe than before chelation. The DOLE exhibits prooxidant effect in presence of Pb in lymphocytes of exposed workers, and its effect is less pronounced following the removal of Pb after standard chelation therapy.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Food and Chemical Toxicology",
title = "Unexpected effect of dry olive leaf extract on the level of DNA damage in lymphocytes of lead intoxicated workers, before and after CaNa(2)EDTA chelation therapy",
volume = "106",
pages = "616-623",
doi = "10.1016/j.fct.2016.12.023"
}

Pirković, A., Dekanski, D., Živković, L., Milanović-Čabarkapa, M., Bajić, V., Topalović, D., Giampieri, F., Gasparrini, M., Battino, M.,& Potparević, B.. (2017). Unexpected effect of dry olive leaf extract on the level of DNA damage in lymphocytes of lead intoxicated workers, before and after CaNa(2)EDTA chelation therapy. in Food and Chemical Toxicology
Pergamon-Elsevier Science Ltd, Oxford., 106, 616-623.
https://doi.org/10.1016/j.fct.2016.12.023

Pirković A, Dekanski D, Živković L, Milanović-Čabarkapa M, Bajić V, Topalović D, Giampieri F, Gasparrini M, Battino M, Potparević B. Unexpected effect of dry olive leaf extract on the level of DNA damage in lymphocytes of lead intoxicated workers, before and after CaNa(2)EDTA chelation therapy. in Food and Chemical Toxicology. 2017;106:616-623.
doi:10.1016/j.fct.2016.12.023 .

Pirković, Andrea, Dekanski, Dragana, Živković, Lada, Milanović-Čabarkapa, Mirjana, Bajić, Vladan, Topalović, Dijana, Giampieri, Francesca, Gasparrini, Massimiliano, Battino, Maurizio, Potparević, Biljana, "Unexpected effect of dry olive leaf extract on the level of DNA damage in lymphocytes of lead intoxicated workers, before and after CaNa(2)EDTA chelation therapy" in Food and Chemical Toxicology, 106 (2017):616-623,
https://doi.org/10.1016/j.fct.2016.12.023 . .

TY  - JOUR
AU  - Čabarkapa, Andrea
AU  - Borozan, Sunčica
AU  - Živković, Lada
AU  - Milanović-Čabarkapa, Mirjana
AU  - Stojanović, Srđan
AU  - Bajić, Vladan
AU  - Spremo-Potparević, Biljana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2440
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3428
AB  - The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and DNA damage and determine relationships between parameters of Pb toxicity and specific biomarkers of oxidative damage.Analysis was conducted of smelter workers with high blood Pb and urine aminolevulinic acid levels and slightly elevated values of coproporphyrin and erythrocyte protoporphyrin IX. Significant decreases of thiol groups and increases in carbonyl groups as protein degradation end products, and of nitrite were detected. Elevated rates of lipid peroxidation and rises in the activities of the antioxidant enzymes Cu-Zn superoxide dismutase and catalase were also observed. Both enzymes showed positive correlations with the blood lead levels and urine coproporphyrin, while thiol groups correlated negatively with the same indices. The genotoxic potential of lead was manifested through an increased number of DNA-damaged cells. Increased activities of serum lactate dehydrogenase isoenzymes indicated cellular damage in the lungs, kidneys, and liver. These lead-induced impairments should be taken into consideration in the assessment of Pb-related health hazards.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Toxicology
T1  - Implications of oxidative stress in occupational exposure to lead on a cellular level
VL  - 97
IS  - 6
SP  - 799
EP  - 813
DO  - 10.1080/02772248.2015.1060973
ER  - 

@article{
author = "Čabarkapa, Andrea and Borozan, Sunčica and Živković, Lada and Milanović-Čabarkapa, Mirjana and Stojanović, Srđan and Bajić, Vladan and Spremo-Potparević, Biljana",
year = "2015",
abstract = "The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and DNA damage and determine relationships between parameters of Pb toxicity and specific biomarkers of oxidative damage.Analysis was conducted of smelter workers with high blood Pb and urine aminolevulinic acid levels and slightly elevated values of coproporphyrin and erythrocyte protoporphyrin IX. Significant decreases of thiol groups and increases in carbonyl groups as protein degradation end products, and of nitrite were detected. Elevated rates of lipid peroxidation and rises in the activities of the antioxidant enzymes Cu-Zn superoxide dismutase and catalase were also observed. Both enzymes showed positive correlations with the blood lead levels and urine coproporphyrin, while thiol groups correlated negatively with the same indices. The genotoxic potential of lead was manifested through an increased number of DNA-damaged cells. Increased activities of serum lactate dehydrogenase isoenzymes indicated cellular damage in the lungs, kidneys, and liver. These lead-induced impairments should be taken into consideration in the assessment of Pb-related health hazards.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Toxicology",
title = "Implications of oxidative stress in occupational exposure to lead on a cellular level",
volume = "97",
number = "6",
pages = "799-813",
doi = "10.1080/02772248.2015.1060973"
}

Čabarkapa, A., Borozan, S., Živković, L., Milanović-Čabarkapa, M., Stojanović, S., Bajić, V.,& Spremo-Potparević, B.. (2015). Implications of oxidative stress in occupational exposure to lead on a cellular level. in Toxicology
Taylor & Francis Ltd, Abingdon., 97(6), 799-813.
https://doi.org/10.1080/02772248.2015.1060973

Čabarkapa A, Borozan S, Živković L, Milanović-Čabarkapa M, Stojanović S, Bajić V, Spremo-Potparević B. Implications of oxidative stress in occupational exposure to lead on a cellular level. in Toxicology. 2015;97(6):799-813.
doi:10.1080/02772248.2015.1060973 .

Čabarkapa, Andrea, Borozan, Sunčica, Živković, Lada, Milanović-Čabarkapa, Mirjana, Stojanović, Srđan, Bajić, Vladan, Spremo-Potparević, Biljana, "Implications of oxidative stress in occupational exposure to lead on a cellular level" in Toxicology, 97, no. 6 (2015):799-813,
https://doi.org/10.1080/02772248.2015.1060973 . .

TY  - JOUR
AU  - Čabarkapa, Andrea
AU  - Borozan, Sunčica
AU  - Živković, Lada
AU  - Milanović-Čabarkapa, Mirjana
AU  - Stojanović, Srđan
AU  - Bajić, Vladan
AU  - Spremo-Potparević, Biljana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2440
AB  - The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and DNA damage and determine relationships between parameters of Pb toxicity and specific biomarkers of oxidative damage.Analysis was conducted of smelter workers with high blood Pb and urine aminolevulinic acid levels and slightly elevated values of coproporphyrin and erythrocyte protoporphyrin IX. Significant decreases of thiol groups and increases in carbonyl groups as protein degradation end products, and of nitrite were detected. Elevated rates of lipid peroxidation and rises in the activities of the antioxidant enzymes Cu-Zn superoxide dismutase and catalase were also observed. Both enzymes showed positive correlations with the blood lead levels and urine coproporphyrin, while thiol groups correlated negatively with the same indices. The genotoxic potential of lead was manifested through an increased number of DNA-damaged cells. Increased activities of serum lactate dehydrogenase isoenzymes indicated cellular damage in the lungs, kidneys, and liver. These lead-induced impairments should be taken into consideration in the assessment of Pb-related health hazards.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Toxicology
T1  - Implications of oxidative stress in occupational exposure to lead on a cellular level
VL  - 97
IS  - 6
SP  - 799
EP  - 813
DO  - 10.1080/02772248.2015.1060973
ER  - 

@article{
author = "Čabarkapa, Andrea and Borozan, Sunčica and Živković, Lada and Milanović-Čabarkapa, Mirjana and Stojanović, Srđan and Bajić, Vladan and Spremo-Potparević, Biljana",
year = "2015",
abstract = "The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and DNA damage and determine relationships between parameters of Pb toxicity and specific biomarkers of oxidative damage.Analysis was conducted of smelter workers with high blood Pb and urine aminolevulinic acid levels and slightly elevated values of coproporphyrin and erythrocyte protoporphyrin IX. Significant decreases of thiol groups and increases in carbonyl groups as protein degradation end products, and of nitrite were detected. Elevated rates of lipid peroxidation and rises in the activities of the antioxidant enzymes Cu-Zn superoxide dismutase and catalase were also observed. Both enzymes showed positive correlations with the blood lead levels and urine coproporphyrin, while thiol groups correlated negatively with the same indices. The genotoxic potential of lead was manifested through an increased number of DNA-damaged cells. Increased activities of serum lactate dehydrogenase isoenzymes indicated cellular damage in the lungs, kidneys, and liver. These lead-induced impairments should be taken into consideration in the assessment of Pb-related health hazards.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Toxicology",
title = "Implications of oxidative stress in occupational exposure to lead on a cellular level",
volume = "97",
number = "6",
pages = "799-813",
doi = "10.1080/02772248.2015.1060973"
}

Čabarkapa, A., Borozan, S., Živković, L., Milanović-Čabarkapa, M., Stojanović, S., Bajić, V.,& Spremo-Potparević, B.. (2015). Implications of oxidative stress in occupational exposure to lead on a cellular level. in Toxicology
Taylor & Francis Ltd, Abingdon., 97(6), 799-813.
https://doi.org/10.1080/02772248.2015.1060973

Čabarkapa A, Borozan S, Živković L, Milanović-Čabarkapa M, Stojanović S, Bajić V, Spremo-Potparević B. Implications of oxidative stress in occupational exposure to lead on a cellular level. in Toxicology. 2015;97(6):799-813.
doi:10.1080/02772248.2015.1060973 .

Čabarkapa, Andrea, Borozan, Sunčica, Živković, Lada, Milanović-Čabarkapa, Mirjana, Stojanović, Srđan, Bajić, Vladan, Spremo-Potparević, Biljana, "Implications of oxidative stress in occupational exposure to lead on a cellular level" in Toxicology, 97, no. 6 (2015):799-813,
https://doi.org/10.1080/02772248.2015.1060973 . .

TY  - JOUR
AU  - Pirković, Andrea
AU  - Borozan, Sunčica
AU  - Živković, Lada
AU  - Stojanović, Srđan
AU  - Milanović-Čabarkapa, Mirjana
AU  - Bajić, Vladan
AU  - Potparević, Biljana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2359
AB  - Lead induced oxidative cellular damage and long-term persistence of associated adverse effects increases risk of late-onset diseases. CaNa(2)EDTA chelation is known to remove contaminating metals and to reduce free radical production. The objective was to investigate the impact of chelation therapy on modulation of lead induced cellular damage, restoration of altered enzyme activities and lipid homeostasis in peripheral blood of workers exposed to lead, by comparing the selected biomarkers obtained prior and after five-day CaNa(2)EDTA chelation intervention. The group of smelting factory workers diagnosed with lead intoxication and current lead exposure 5.8 +/- 1.2 years were administered five-day CaNa(2)EDTA chelation. Elevated baseline activity of antioxidant enzymes Cu, Zn-SOD and CAT as well as depleted thiols and increased protein degradation products-carbonyl groups and nitrites, pointing to Pb induced oxidative damage, were restored toward normal values following the treatment. Lead showed inhibitor potency on both RBC AChE and BChE in exposed workers, and chelation re-established the activity of BChE, while RBC AChE remained unaffected. Also, genotoxic effect of lead detected in peripheral blood lymphocytes was significantly decreased after therapy, exhibiting 18.9% DNA damage reduction. Administration of chelation reversed the depressed activity of serum PON 1 and significantly decreased lipid peroxidation detected by the post-chelation reduction of MDA levels. Lactate dehydrogenase LDF1-5 isoenzymes levels showed evident but no significant trend of restoring toward normal control values following chelation. CaNa(2)EDTA chelation ameliorates the alterations linked with Pb mediated oxidative stress, indicating possible benefits in reducing health risks associated with increased oxidative damage in lead exposed populations.
PB  - Elsevier Ireland Ltd, Clare
T2  - Chemico-Biological Interactions
T1  - CaNa(2)EDTA chelation attenuates cell damage in workers exposed to lead-a pilot study
VL  - 242
SP  - 171
EP  - 178
DO  - 10.1016/j.cbi.2015.10.002
ER  - 

@article{
author = "Pirković, Andrea and Borozan, Sunčica and Živković, Lada and Stojanović, Srđan and Milanović-Čabarkapa, Mirjana and Bajić, Vladan and Potparević, Biljana",
year = "2015",
abstract = "Lead induced oxidative cellular damage and long-term persistence of associated adverse effects increases risk of late-onset diseases. CaNa(2)EDTA chelation is known to remove contaminating metals and to reduce free radical production. The objective was to investigate the impact of chelation therapy on modulation of lead induced cellular damage, restoration of altered enzyme activities and lipid homeostasis in peripheral blood of workers exposed to lead, by comparing the selected biomarkers obtained prior and after five-day CaNa(2)EDTA chelation intervention. The group of smelting factory workers diagnosed with lead intoxication and current lead exposure 5.8 +/- 1.2 years were administered five-day CaNa(2)EDTA chelation. Elevated baseline activity of antioxidant enzymes Cu, Zn-SOD and CAT as well as depleted thiols and increased protein degradation products-carbonyl groups and nitrites, pointing to Pb induced oxidative damage, were restored toward normal values following the treatment. Lead showed inhibitor potency on both RBC AChE and BChE in exposed workers, and chelation re-established the activity of BChE, while RBC AChE remained unaffected. Also, genotoxic effect of lead detected in peripheral blood lymphocytes was significantly decreased after therapy, exhibiting 18.9% DNA damage reduction. Administration of chelation reversed the depressed activity of serum PON 1 and significantly decreased lipid peroxidation detected by the post-chelation reduction of MDA levels. Lactate dehydrogenase LDF1-5 isoenzymes levels showed evident but no significant trend of restoring toward normal control values following chelation. CaNa(2)EDTA chelation ameliorates the alterations linked with Pb mediated oxidative stress, indicating possible benefits in reducing health risks associated with increased oxidative damage in lead exposed populations.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Chemico-Biological Interactions",
title = "CaNa(2)EDTA chelation attenuates cell damage in workers exposed to lead-a pilot study",
volume = "242",
pages = "171-178",
doi = "10.1016/j.cbi.2015.10.002"
}

Pirković, A., Borozan, S., Živković, L., Stojanović, S., Milanović-Čabarkapa, M., Bajić, V.,& Potparević, B.. (2015). CaNa(2)EDTA chelation attenuates cell damage in workers exposed to lead-a pilot study. in Chemico-Biological Interactions
Elsevier Ireland Ltd, Clare., 242, 171-178.
https://doi.org/10.1016/j.cbi.2015.10.002

Pirković A, Borozan S, Živković L, Stojanović S, Milanović-Čabarkapa M, Bajić V, Potparević B. CaNa(2)EDTA chelation attenuates cell damage in workers exposed to lead-a pilot study. in Chemico-Biological Interactions. 2015;242:171-178.
doi:10.1016/j.cbi.2015.10.002 .

Pirković, Andrea, Borozan, Sunčica, Živković, Lada, Stojanović, Srđan, Milanović-Čabarkapa, Mirjana, Bajić, Vladan, Potparević, Biljana, "CaNa(2)EDTA chelation attenuates cell damage in workers exposed to lead-a pilot study" in Chemico-Biological Interactions, 242 (2015):171-178,
https://doi.org/10.1016/j.cbi.2015.10.002 . .

TY  - CONF
AU  - Čabarkapa, Andrea
AU  - Milanović-Čabarkapa, Mirjana
AU  - Živković, Lada
AU  - Borozan, Sunčica
AU  - Bajić, Vladan
AU  - Topalović, Dijana
AU  - Spremo-Potparević, Biljana
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5297
AB  - One of the numerous adverse manifestations following lead (Pb) exposure is production of free radicals and increased oxidative stress, which can lead to altered enyzme functioning and  degradation of structural components in organism. The objective was to investigate the effects of Pb exposure on biomarkers of oxidative stress and antioxidant defence system in 15 adult male workers after occupational exposure to lead versus unexposed healthy controls. The impact of Pb on oxidative stress parameters was evaluated by measuring blood and urinary Pb concentrations, plasma levels of antioxidant enzymes catalase (CAT), superoxide dismutase (SOD), level of malondialdehyde (MDA) as the lipid peroxidation indicator, concentrations of carbonyl groups, plasma protein thiols and nitrites as biomarkers of protein oxidative modification. The results of MDA concentration revealed increased lipid peroxidation (P < 0.001), while the rise of protein carbonyl and nitrite levels (P < 0.001, P < 0.006, respectively) and decrease of plasma thiols (P < 0.001) indicated significant protein damage in Pb exposed workers, compared to unexposed controls. Increased activity of antioxidant enzymes SOD and CAT (P < 0.001) was also determined in exposed group. Elevated blood lead levels showed strong  positive correlation (r=0.809, P < 0.001) with increased CAT concentration. Our findings indicate that Pb promotes oxidative damage in exposed subjects, and that increased lead content can affect the activity of antioxidant enzymes. Considering that oxidative stress has been recognized in etiology of many diseases, future explorations on impact of these changes in populations occupationally exposed to lead are suggested.
PB  - Serbian Society of Toxicology
C3  - 11th Serbian Congress of Toxicology
T1  - Biomarkers of Oxidative Stress in Workers Exposed To Lead
SP  - 7
EP  - 7
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5297
ER  - 

@conference{
author = "Čabarkapa, Andrea and Milanović-Čabarkapa, Mirjana and Živković, Lada and Borozan, Sunčica and Bajić, Vladan and Topalović, Dijana and Spremo-Potparević, Biljana",
year = "2014",
abstract = "One of the numerous adverse manifestations following lead (Pb) exposure is production of free radicals and increased oxidative stress, which can lead to altered enyzme functioning and  degradation of structural components in organism. The objective was to investigate the effects of Pb exposure on biomarkers of oxidative stress and antioxidant defence system in 15 adult male workers after occupational exposure to lead versus unexposed healthy controls. The impact of Pb on oxidative stress parameters was evaluated by measuring blood and urinary Pb concentrations, plasma levels of antioxidant enzymes catalase (CAT), superoxide dismutase (SOD), level of malondialdehyde (MDA) as the lipid peroxidation indicator, concentrations of carbonyl groups, plasma protein thiols and nitrites as biomarkers of protein oxidative modification. The results of MDA concentration revealed increased lipid peroxidation (P < 0.001), while the rise of protein carbonyl and nitrite levels (P < 0.001, P < 0.006, respectively) and decrease of plasma thiols (P < 0.001) indicated significant protein damage in Pb exposed workers, compared to unexposed controls. Increased activity of antioxidant enzymes SOD and CAT (P < 0.001) was also determined in exposed group. Elevated blood lead levels showed strong  positive correlation (r=0.809, P < 0.001) with increased CAT concentration. Our findings indicate that Pb promotes oxidative damage in exposed subjects, and that increased lead content can affect the activity of antioxidant enzymes. Considering that oxidative stress has been recognized in etiology of many diseases, future explorations on impact of these changes in populations occupationally exposed to lead are suggested.",
publisher = "Serbian Society of Toxicology",
journal = "11th Serbian Congress of Toxicology",
title = "Biomarkers of Oxidative Stress in Workers Exposed To Lead",
pages = "7-7",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5297"
}

Čabarkapa, A., Milanović-Čabarkapa, M., Živković, L., Borozan, S., Bajić, V., Topalović, D.,& Spremo-Potparević, B.. (2014). Biomarkers of Oxidative Stress in Workers Exposed To Lead. in 11th Serbian Congress of Toxicology
Serbian Society of Toxicology., 7-7.
https://hdl.handle.net/21.15107/rcub_farfar_5297

Čabarkapa A, Milanović-Čabarkapa M, Živković L, Borozan S, Bajić V, Topalović D, Spremo-Potparević B. Biomarkers of Oxidative Stress in Workers Exposed To Lead. in 11th Serbian Congress of Toxicology. 2014;:7-7.
https://hdl.handle.net/21.15107/rcub_farfar_5297 .

Čabarkapa, Andrea, Milanović-Čabarkapa, Mirjana, Živković, Lada, Borozan, Sunčica, Bajić, Vladan, Topalović, Dijana, Spremo-Potparević, Biljana, "Biomarkers of Oxidative Stress in Workers Exposed To Lead" in 11th Serbian Congress of Toxicology (2014):7-7,
https://hdl.handle.net/21.15107/rcub_farfar_5297 .

TY  - CONF
AU  - Čabarkapa, Andrea
AU  - Milanović-Čabarkapa, Mirjana
AU  - Živković, Lada
AU  - Žukovec, Dijana
AU  - Bajić, Vladan
AU  - Spremo-Potparević, Biljana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5232
AB  - INTRODUCTION: Pathogenetic effect of lead (Pb) is multifactorial and it is known that one of the ways which lead damages cellular components is by direct formation of reactive oxygen species. ...
PB  - Eko centar, centar za sociološka istraživanja i dokumentaciju
C3  - Svet rada
T1  - EDTA  chelation therapy decreases oxidative DNA damage in the blood cells of workers occupationaly exposed to lead
T1  - EDTA helatna terapija smanjuje oksidativno DNK oštećenje u limfocitima periferne krvi radnika profesionalno izloženih olovu
VL  - 9
IS  - 4
SP  - 541
EP  - 543
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5232
ER  - 

@conference{
author = "Čabarkapa, Andrea and Milanović-Čabarkapa, Mirjana and Živković, Lada and Žukovec, Dijana and Bajić, Vladan and Spremo-Potparević, Biljana",
year = "2012",
abstract = "INTRODUCTION: Pathogenetic effect of lead (Pb) is multifactorial and it is known that one of the ways which lead damages cellular components is by direct formation of reactive oxygen species. ...",
publisher = "Eko centar, centar za sociološka istraživanja i dokumentaciju",
journal = "Svet rada",
title = "EDTA  chelation therapy decreases oxidative DNA damage in the blood cells of workers occupationaly exposed to lead, EDTA helatna terapija smanjuje oksidativno DNK oštećenje u limfocitima periferne krvi radnika profesionalno izloženih olovu",
volume = "9",
number = "4",
pages = "541-543",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5232"
}

Čabarkapa, A., Milanović-Čabarkapa, M., Živković, L., Žukovec, D., Bajić, V.,& Spremo-Potparević, B.. (2012). EDTA  chelation therapy decreases oxidative DNA damage in the blood cells of workers occupationaly exposed to lead. in Svet rada
Eko centar, centar za sociološka istraživanja i dokumentaciju., 9(4), 541-543.
https://hdl.handle.net/21.15107/rcub_farfar_5232

Čabarkapa A, Milanović-Čabarkapa M, Živković L, Žukovec D, Bajić V, Spremo-Potparević B. EDTA  chelation therapy decreases oxidative DNA damage in the blood cells of workers occupationaly exposed to lead. in Svet rada. 2012;9(4):541-543.
https://hdl.handle.net/21.15107/rcub_farfar_5232 .

Čabarkapa, Andrea, Milanović-Čabarkapa, Mirjana, Živković, Lada, Žukovec, Dijana, Bajić, Vladan, Spremo-Potparević, Biljana, "EDTA  chelation therapy decreases oxidative DNA damage in the blood cells of workers occupationaly exposed to lead" in Svet rada, 9, no. 4 (2012):541-543,
https://hdl.handle.net/21.15107/rcub_farfar_5232 .