Ivanisević, L

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  • Ivanisević, L (1)
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Determination of sodium fusidate in dosage forms by high performance liquid chromatography

Vladimirov, S; Ivanisević, L; Agbaba, Danica; Brborić, Jasmina; Živanov-Stakić, Dobrila

(Srpsko hemijsko društvo, Beograd, 1998)

TY  - JOUR
AU  - Vladimirov, S
AU  - Ivanisević, L
AU  - Agbaba, Danica
AU  - Brborić, Jasmina
AU  - Živanov-Stakić, Dobrila
PY  - 1998
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/184
AB  - A simple HPLC procedure, suitable for the determination of sodium fusidate (SF) in dosage forms, was developed. The method involves using a UV detector (208 nm) in the presence of basic buffered media (pH 7.25) under reversed-phase conditions (Supelcosil(R) LC18(TM), 3 mu m particles). The linear regression between the concentration of SF and the peak area, y = -4.4566 + 8.9238x with a coefficient of correlation r = 0.9985, was confirmed for SF in the concentration range from 25 mu g/ml to 150 mu g/ml. The detection limit of SF was 12.5 mu g/ml. The HPLC method was applied for the determination of SF in dosage forms: Stanicid(R) coated tablets, Stanicid(R) ointment and Stanicid(R) sterile gauze dressing. The concentrations and statistical parameters of sodium fusidate for all the investigated dosage forms were satisfactory and ranged from 100.41 to 105.39% (the R. S. D. ranged from 1.51 to 2.75%).
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Determination of sodium fusidate in dosage forms by high performance liquid chromatography
VL  - 63
IS  - 6
SP  - 475
EP  - 480
UR  - https://hdl.handle.net/21.15107/rcub_farfar_184
ER  - 
@article{
author = "Vladimirov, S and Ivanisević, L and Agbaba, Danica and Brborić, Jasmina and Živanov-Stakić, Dobrila",
year = "1998",
abstract = "A simple HPLC procedure, suitable for the determination of sodium fusidate (SF) in dosage forms, was developed. The method involves using a UV detector (208 nm) in the presence of basic buffered media (pH 7.25) under reversed-phase conditions (Supelcosil(R) LC18(TM), 3 mu m particles). The linear regression between the concentration of SF and the peak area, y = -4.4566 + 8.9238x with a coefficient of correlation r = 0.9985, was confirmed for SF in the concentration range from 25 mu g/ml to 150 mu g/ml. The detection limit of SF was 12.5 mu g/ml. The HPLC method was applied for the determination of SF in dosage forms: Stanicid(R) coated tablets, Stanicid(R) ointment and Stanicid(R) sterile gauze dressing. The concentrations and statistical parameters of sodium fusidate for all the investigated dosage forms were satisfactory and ranged from 100.41 to 105.39% (the R. S. D. ranged from 1.51 to 2.75%).",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Determination of sodium fusidate in dosage forms by high performance liquid chromatography",
volume = "63",
number = "6",
pages = "475-480",
url = "https://hdl.handle.net/21.15107/rcub_farfar_184"
}
Vladimirov, S., Ivanisević, L., Agbaba, D., Brborić, J.,& Živanov-Stakić, D.. (1998). Determination of sodium fusidate in dosage forms by high performance liquid chromatography. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 63(6), 475-480.
https://hdl.handle.net/21.15107/rcub_farfar_184
Vladimirov S, Ivanisević L, Agbaba D, Brborić J, Živanov-Stakić D. Determination of sodium fusidate in dosage forms by high performance liquid chromatography. in Journal of the Serbian Chemical Society. 1998;63(6):475-480.
https://hdl.handle.net/21.15107/rcub_farfar_184 .
Vladimirov, S, Ivanisević, L, Agbaba, Danica, Brborić, Jasmina, Živanov-Stakić, Dobrila, "Determination of sodium fusidate in dosage forms by high performance liquid chromatography" in Journal of the Serbian Chemical Society, 63, no. 6 (1998):475-480,
https://hdl.handle.net/21.15107/rcub_farfar_184 .