TY  - CONF
AU  - Živković, Lada
AU  - Topalović, Dijana
AU  - Borozan, Sunčica
AU  - Bajić, Vladan
AU  - Dimitrijević Srećković, Vesna
AU  - Pirković, Andrea
AU  - Petrović, Hristina
AU  - Spremo-Potparević, Biljana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4630
PB  - Department of Pharmacology and Toxicology, University of Maastrich, The Netherlands
C3  - Joint EEMGS meeting & International Comet Assay Workshop, 2022 - Abstract Book
T1  - Dihydroquercetin (Taxifolin) and Biochaga attenuate oxidative DNA damage in lymphocytes of obese subjects in vitro
SP  - 94
EP  - 94
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4630
ER  - 

@conference{
author = "Živković, Lada and Topalović, Dijana and Borozan, Sunčica and Bajić, Vladan and Dimitrijević Srećković, Vesna and Pirković, Andrea and Petrović, Hristina and Spremo-Potparević, Biljana",
year = "2022",
publisher = "Department of Pharmacology and Toxicology, University of Maastrich, The Netherlands",
journal = "Joint EEMGS meeting & International Comet Assay Workshop, 2022 - Abstract Book",
title = "Dihydroquercetin (Taxifolin) and Biochaga attenuate oxidative DNA damage in lymphocytes of obese subjects in vitro",
pages = "94-94",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4630"
}

Živković, L., Topalović, D., Borozan, S., Bajić, V., Dimitrijević Srećković, V., Pirković, A., Petrović, H.,& Spremo-Potparević, B.. (2022). Dihydroquercetin (Taxifolin) and Biochaga attenuate oxidative DNA damage in lymphocytes of obese subjects in vitro. in Joint EEMGS meeting & International Comet Assay Workshop, 2022 - Abstract Book
Department of Pharmacology and Toxicology, University of Maastrich, The Netherlands., 94-94.
https://hdl.handle.net/21.15107/rcub_farfar_4630

Živković L, Topalović D, Borozan S, Bajić V, Dimitrijević Srećković V, Pirković A, Petrović H, Spremo-Potparević B. Dihydroquercetin (Taxifolin) and Biochaga attenuate oxidative DNA damage in lymphocytes of obese subjects in vitro. in Joint EEMGS meeting & International Comet Assay Workshop, 2022 - Abstract Book. 2022;:94-94.
https://hdl.handle.net/21.15107/rcub_farfar_4630 .

Živković, Lada, Topalović, Dijana, Borozan, Sunčica, Bajić, Vladan, Dimitrijević Srećković, Vesna, Pirković, Andrea, Petrović, Hristina, Spremo-Potparević, Biljana, "Dihydroquercetin (Taxifolin) and Biochaga attenuate oxidative DNA damage in lymphocytes of obese subjects in vitro" in Joint EEMGS meeting & International Comet Assay Workshop, 2022 - Abstract Book (2022):94-94,
https://hdl.handle.net/21.15107/rcub_farfar_4630 .

TY  - JOUR
AU  - Milić, Mirta
AU  - Ceppi, Marcello
AU  - Bruzzone, Marco
AU  - Azqueta, Amaya
AU  - Brunborg, Gunnar
AU  - Godschalk, Roger
AU  - Koppen, Gudrun
AU  - Langie, Sabine
AU  - Møller, Peter
AU  - Teixeira, João Paulo
AU  - Alija, Avdulla
AU  - Anderson, Diana
AU  - Andrade, Vanessa
AU  - Andreoli, Cristina
AU  - Asllani, Fisnik
AU  - Bangkoglu, Ezgi Eyluel
AU  - Barančoková, Magdalena
AU  - Basaran, Nursen
AU  - Boutet-Robinet, Elisa
AU  - Buschini, Annamaria
AU  - Cavallo, Delia
AU  - Costa Pereira, Cristiana
AU  - Costa, Carla
AU  - Costa, Solange
AU  - Da Silva, Juliana
AU  - Del Boˊ, Cristian
AU  - Dimitrijević Srećković, Vesna
AU  - Đelić, Ninoslav
AU  - Dobrzyńska, Malgorzata
AU  - Duračková, Zdenka
AU  - Dvořáková, Monika
AU  - Gajski, Goran
AU  - Galati, Serena
AU  - García Lima, Omar
AU  - Giovannelli, Lisa
AU  - Goroshinskaya, Irina A.
AU  - Grindel, Annemarie
AU  - Gutzkow, Kristine B.
AU  - Hernández, Alba
AU  - Hernández, Carlos
AU  - Holven, Kirsten B.
AU  - Ibero-Baraibar, Idoia
AU  - Ottestad, Inger
AU  - Kadioglu, Ela
AU  - Kažimirová, Alena
AU  - Kuznetsova, Elena
AU  - Ladeira, Carina
AU  - Laffon, Blanca
AU  - Lamonaca, Palma
AU  - Lebailly, Pierre
AU  - Louro, Henriqueta
AU  - Mandina Cardoso, Tania
AU  - Marcon, Francesca
AU  - Marcos, Ricard
AU  - Moretti, Massimo
AU  - Moretti, Silvia
AU  - Najafzadeh, Mojgan
AU  - Nemeth, Zsuzsanna
AU  - Neri, Monica
AU  - Novotna, Bozena
AU  - Orlow, Irene
AU  - Paduchova, Zuzana
AU  - Pastor, Susana
AU  - Perdry, Hervé
AU  - Spremo-Potparević, Biljana
AU  - Ramadhani, Dwi
AU  - Riso, Patrizia
AU  - Rohr, Paula
AU  - Rojas, Emilio
AU  - Rossner, Pavel
AU  - Safar, Anna
AU  - Sardas, Semra
AU  - Silva, Maria João
AU  - Sirota, Nikolay
AU  - Smolkova, Bozena
AU  - Staruchova, Marta
AU  - Stetina, Rudolf
AU  - Stopper, Helga
AU  - Surikova, Ekaterina I.
AU  - Ulven, Stine M.
AU  - Ursini, Cinzia Lucia
AU  - Valdiglesias, Vanessa
AU  - Valverde, Mahara
AU  - Vodicka, Pavel
AU  - Volkovova, Katarina
AU  - Wagner, Karl-Heinz
AU  - Živković, Lada
AU  - Dušinská, Maria
AU  - Collins, Andrew R.
AU  - Bonassi, Stefano
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3791
AB  - The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification of those factors that can explain the large inter-individual and inter-laboratory variation. International collaborative initiatives such as the hCOMET project - a COST Action launched in 2016 - represent a valuable tool to meet this challenge. The aims of hCOMET were to establish reference values for the level of DNA damage in humans, to investigate the effect of host factors, lifestyle and exposure to genotoxic agents, and to compare different sources of assay variability. A database of 19,320 subjects was generated, pooling data from 105 studies run by 44 laboratories in 26 countries between 1999 and 2019. A mixed random effect log-linear model, in parallel with a classic meta-analysis, was applied to take into account the extensive heterogeneity of data, due to descriptor, specimen and protocol variability. As a result of this analysis interquartile intervals of DNA strand breaks (which includes alkali-labile sites) were reported for tail intensity, tail length, and tail moment (comet assay descriptors). A small variation by age was reported in some datasets, suggesting higher DNA damage in oldest age-classes, while no effect could be shown for sex or smoking habit, although the lack of data on heavy smokers has still to be considered. Finally, highly significant differences in DNA damage were found for most exposures investigated in specific studies. In conclusion, these data, which confirm that DNA damage measured by the comet assay is an excellent biomarker of exposure in several conditions, may contribute to improving the quality of study design and to the standardization of results of the comet assay in human populations.
PB  - Elsevier B.V.
T2  - Mutation Research - Reviews in Mutation Research
T1  - The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders
VL  - 787
DO  - 10.1016/j.mrrev.2021.108371
ER  - 

@article{
author = "Milić, Mirta and Ceppi, Marcello and Bruzzone, Marco and Azqueta, Amaya and Brunborg, Gunnar and Godschalk, Roger and Koppen, Gudrun and Langie, Sabine and Møller, Peter and Teixeira, João Paulo and Alija, Avdulla and Anderson, Diana and Andrade, Vanessa and Andreoli, Cristina and Asllani, Fisnik and Bangkoglu, Ezgi Eyluel and Barančoková, Magdalena and Basaran, Nursen and Boutet-Robinet, Elisa and Buschini, Annamaria and Cavallo, Delia and Costa Pereira, Cristiana and Costa, Carla and Costa, Solange and Da Silva, Juliana and Del Boˊ, Cristian and Dimitrijević Srećković, Vesna and Đelić, Ninoslav and Dobrzyńska, Malgorzata and Duračková, Zdenka and Dvořáková, Monika and Gajski, Goran and Galati, Serena and García Lima, Omar and Giovannelli, Lisa and Goroshinskaya, Irina A. and Grindel, Annemarie and Gutzkow, Kristine B. and Hernández, Alba and Hernández, Carlos and Holven, Kirsten B. and Ibero-Baraibar, Idoia and Ottestad, Inger and Kadioglu, Ela and Kažimirová, Alena and Kuznetsova, Elena and Ladeira, Carina and Laffon, Blanca and Lamonaca, Palma and Lebailly, Pierre and Louro, Henriqueta and Mandina Cardoso, Tania and Marcon, Francesca and Marcos, Ricard and Moretti, Massimo and Moretti, Silvia and Najafzadeh, Mojgan and Nemeth, Zsuzsanna and Neri, Monica and Novotna, Bozena and Orlow, Irene and Paduchova, Zuzana and Pastor, Susana and Perdry, Hervé and Spremo-Potparević, Biljana and Ramadhani, Dwi and Riso, Patrizia and Rohr, Paula and Rojas, Emilio and Rossner, Pavel and Safar, Anna and Sardas, Semra and Silva, Maria João and Sirota, Nikolay and Smolkova, Bozena and Staruchova, Marta and Stetina, Rudolf and Stopper, Helga and Surikova, Ekaterina I. and Ulven, Stine M. and Ursini, Cinzia Lucia and Valdiglesias, Vanessa and Valverde, Mahara and Vodicka, Pavel and Volkovova, Katarina and Wagner, Karl-Heinz and Živković, Lada and Dušinská, Maria and Collins, Andrew R. and Bonassi, Stefano",
year = "2021",
abstract = "The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification of those factors that can explain the large inter-individual and inter-laboratory variation. International collaborative initiatives such as the hCOMET project - a COST Action launched in 2016 - represent a valuable tool to meet this challenge. The aims of hCOMET were to establish reference values for the level of DNA damage in humans, to investigate the effect of host factors, lifestyle and exposure to genotoxic agents, and to compare different sources of assay variability. A database of 19,320 subjects was generated, pooling data from 105 studies run by 44 laboratories in 26 countries between 1999 and 2019. A mixed random effect log-linear model, in parallel with a classic meta-analysis, was applied to take into account the extensive heterogeneity of data, due to descriptor, specimen and protocol variability. As a result of this analysis interquartile intervals of DNA strand breaks (which includes alkali-labile sites) were reported for tail intensity, tail length, and tail moment (comet assay descriptors). A small variation by age was reported in some datasets, suggesting higher DNA damage in oldest age-classes, while no effect could be shown for sex or smoking habit, although the lack of data on heavy smokers has still to be considered. Finally, highly significant differences in DNA damage were found for most exposures investigated in specific studies. In conclusion, these data, which confirm that DNA damage measured by the comet assay is an excellent biomarker of exposure in several conditions, may contribute to improving the quality of study design and to the standardization of results of the comet assay in human populations.",
publisher = "Elsevier B.V.",
journal = "Mutation Research - Reviews in Mutation Research",
title = "The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders",
volume = "787",
doi = "10.1016/j.mrrev.2021.108371"
}

Milić, M., Ceppi, M., Bruzzone, M., Azqueta, A., Brunborg, G., Godschalk, R., Koppen, G., Langie, S., Møller, P., Teixeira, J. P., Alija, A., Anderson, D., Andrade, V., Andreoli, C., Asllani, F., Bangkoglu, E. E., Barančoková, M., Basaran, N., Boutet-Robinet, E., Buschini, A., Cavallo, D., Costa Pereira, C., Costa, C., Costa, S., Da Silva, J., Del Boˊ, C., Dimitrijević Srećković, V., Đelić, N., Dobrzyńska, M., Duračková, Z., Dvořáková, M., Gajski, G., Galati, S., García Lima, O., Giovannelli, L., Goroshinskaya, I. A., Grindel, A., Gutzkow, K. B., Hernández, A., Hernández, C., Holven, K. B., Ibero-Baraibar, I., Ottestad, I., Kadioglu, E., Kažimirová, A., Kuznetsova, E., Ladeira, C., Laffon, B., Lamonaca, P., Lebailly, P., Louro, H., Mandina Cardoso, T., Marcon, F., Marcos, R., Moretti, M., Moretti, S., Najafzadeh, M., Nemeth, Z., Neri, M., Novotna, B., Orlow, I., Paduchova, Z., Pastor, S., Perdry, H., Spremo-Potparević, B., Ramadhani, D., Riso, P., Rohr, P., Rojas, E., Rossner, P., Safar, A., Sardas, S., Silva, M. J., Sirota, N., Smolkova, B., Staruchova, M., Stetina, R., Stopper, H., Surikova, E. I., Ulven, S. M., Ursini, C. L., Valdiglesias, V., Valverde, M., Vodicka, P., Volkovova, K., Wagner, K., Živković, L., Dušinská, M., Collins, A. R.,& Bonassi, S.. (2021). The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders. in Mutation Research - Reviews in Mutation Research
Elsevier B.V.., 787.
https://doi.org/10.1016/j.mrrev.2021.108371

Milić M, Ceppi M, Bruzzone M, Azqueta A, Brunborg G, Godschalk R, Koppen G, Langie S, Møller P, Teixeira JP, Alija A, Anderson D, Andrade V, Andreoli C, Asllani F, Bangkoglu EE, Barančoková M, Basaran N, Boutet-Robinet E, Buschini A, Cavallo D, Costa Pereira C, Costa C, Costa S, Da Silva J, Del Boˊ C, Dimitrijević Srećković V, Đelić N, Dobrzyńska M, Duračková Z, Dvořáková M, Gajski G, Galati S, García Lima O, Giovannelli L, Goroshinskaya IA, Grindel A, Gutzkow KB, Hernández A, Hernández C, Holven KB, Ibero-Baraibar I, Ottestad I, Kadioglu E, Kažimirová A, Kuznetsova E, Ladeira C, Laffon B, Lamonaca P, Lebailly P, Louro H, Mandina Cardoso T, Marcon F, Marcos R, Moretti M, Moretti S, Najafzadeh M, Nemeth Z, Neri M, Novotna B, Orlow I, Paduchova Z, Pastor S, Perdry H, Spremo-Potparević B, Ramadhani D, Riso P, Rohr P, Rojas E, Rossner P, Safar A, Sardas S, Silva MJ, Sirota N, Smolkova B, Staruchova M, Stetina R, Stopper H, Surikova EI, Ulven SM, Ursini CL, Valdiglesias V, Valverde M, Vodicka P, Volkovova K, Wagner K, Živković L, Dušinská M, Collins AR, Bonassi S. The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders. in Mutation Research - Reviews in Mutation Research. 2021;787.
doi:10.1016/j.mrrev.2021.108371 .

Milić, Mirta, Ceppi, Marcello, Bruzzone, Marco, Azqueta, Amaya, Brunborg, Gunnar, Godschalk, Roger, Koppen, Gudrun, Langie, Sabine, Møller, Peter, Teixeira, João Paulo, Alija, Avdulla, Anderson, Diana, Andrade, Vanessa, Andreoli, Cristina, Asllani, Fisnik, Bangkoglu, Ezgi Eyluel, Barančoková, Magdalena, Basaran, Nursen, Boutet-Robinet, Elisa, Buschini, Annamaria, Cavallo, Delia, Costa Pereira, Cristiana, Costa, Carla, Costa, Solange, Da Silva, Juliana, Del Boˊ, Cristian, Dimitrijević Srećković, Vesna, Đelić, Ninoslav, Dobrzyńska, Malgorzata, Duračková, Zdenka, Dvořáková, Monika, Gajski, Goran, Galati, Serena, García Lima, Omar, Giovannelli, Lisa, Goroshinskaya, Irina A., Grindel, Annemarie, Gutzkow, Kristine B., Hernández, Alba, Hernández, Carlos, Holven, Kirsten B., Ibero-Baraibar, Idoia, Ottestad, Inger, Kadioglu, Ela, Kažimirová, Alena, Kuznetsova, Elena, Ladeira, Carina, Laffon, Blanca, Lamonaca, Palma, Lebailly, Pierre, Louro, Henriqueta, Mandina Cardoso, Tania, Marcon, Francesca, Marcos, Ricard, Moretti, Massimo, Moretti, Silvia, Najafzadeh, Mojgan, Nemeth, Zsuzsanna, Neri, Monica, Novotna, Bozena, Orlow, Irene, Paduchova, Zuzana, Pastor, Susana, Perdry, Hervé, Spremo-Potparević, Biljana, Ramadhani, Dwi, Riso, Patrizia, Rohr, Paula, Rojas, Emilio, Rossner, Pavel, Safar, Anna, Sardas, Semra, Silva, Maria João, Sirota, Nikolay, Smolkova, Bozena, Staruchova, Marta, Stetina, Rudolf, Stopper, Helga, Surikova, Ekaterina I., Ulven, Stine M., Ursini, Cinzia Lucia, Valdiglesias, Vanessa, Valverde, Mahara, Vodicka, Pavel, Volkovova, Katarina, Wagner, Karl-Heinz, Živković, Lada, Dušinská, Maria, Collins, Andrew R., Bonassi, Stefano, "The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders" in Mutation Research - Reviews in Mutation Research, 787 (2021),
https://doi.org/10.1016/j.mrrev.2021.108371 . .

TY  - JOUR
AU  - Janać, Jelena
AU  - Zeljković, Aleksandra
AU  - Jelić-Ivanović, Zorana
AU  - Dimitrijević-Srećković, Vesna
AU  - Vekić, Jelena
AU  - Miljković, Milica
AU  - Stefanović, Aleksandra
AU  - Kotur-Stevuljević, Jelena
AU  - Ivanišević, Jasmina
AU  - Spasojević-Kalimanovska, Vesna
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3803
AB  - Background: We evaluated the qualitative characteristics of high-density lipoprotein (HDL) particles in metabolically healthy and unhealthy overweight and obese subjects. Methods: The study involved 115 subject individuals classified as metabolically healthy and unhealthy, as in overweight and obese groups. Commercial enzyme-linked immunosorbent assay (ELISA) kits were used to measure oxidized HDL (OxHDL) and serum amyloid A (SAA) concentrations. Lipoprotein subfractions were separated using nondenaturing gradient gel electrophoresis. Results: An independent association was shown between increased OxHDL/HDL-cholesterol ratio and the occurrence of metabolically unhealthy phenotype in the overweight and obese groups. The OxHDL/HDL-cholesterol ratio showed excellent and acceptable diagnostic accuracy in determination of metabolic health phenotypes (overweight group, AUC = 0.881; obese group, AUC = 0.765). Accumulation of smaller HDL particles in metabolically unhealthy subjects was verified by lipoprotein subfraction analysis. SAA concentrations did not differ significantly between phenotypes. Conclusions: Increased OxHDL/HDL-cholesterol ratio may be a potential indicator of disturbed metabolic health in overweight and obese individuals.
PB  - Oxford University Press
T2  - Lab Medicine
T1  - Increased oxidized high-density lipoprotein/ high-density lipoprotein-cholesterol ratio as a potential indicator of disturbed metabolic health in overweight and obese individuals
VL  - 51
IS  - 1
SP  - 24
EP  - 33
DO  - 10.1093/labmed/lmz017
ER  - 

@article{
author = "Janać, Jelena and Zeljković, Aleksandra and Jelić-Ivanović, Zorana and Dimitrijević-Srećković, Vesna and Vekić, Jelena and Miljković, Milica and Stefanović, Aleksandra and Kotur-Stevuljević, Jelena and Ivanišević, Jasmina and Spasojević-Kalimanovska, Vesna",
year = "2020",
abstract = "Background: We evaluated the qualitative characteristics of high-density lipoprotein (HDL) particles in metabolically healthy and unhealthy overweight and obese subjects. Methods: The study involved 115 subject individuals classified as metabolically healthy and unhealthy, as in overweight and obese groups. Commercial enzyme-linked immunosorbent assay (ELISA) kits were used to measure oxidized HDL (OxHDL) and serum amyloid A (SAA) concentrations. Lipoprotein subfractions were separated using nondenaturing gradient gel electrophoresis. Results: An independent association was shown between increased OxHDL/HDL-cholesterol ratio and the occurrence of metabolically unhealthy phenotype in the overweight and obese groups. The OxHDL/HDL-cholesterol ratio showed excellent and acceptable diagnostic accuracy in determination of metabolic health phenotypes (overweight group, AUC = 0.881; obese group, AUC = 0.765). Accumulation of smaller HDL particles in metabolically unhealthy subjects was verified by lipoprotein subfraction analysis. SAA concentrations did not differ significantly between phenotypes. Conclusions: Increased OxHDL/HDL-cholesterol ratio may be a potential indicator of disturbed metabolic health in overweight and obese individuals.",
publisher = "Oxford University Press",
journal = "Lab Medicine",
title = "Increased oxidized high-density lipoprotein/ high-density lipoprotein-cholesterol ratio as a potential indicator of disturbed metabolic health in overweight and obese individuals",
volume = "51",
number = "1",
pages = "24-33",
doi = "10.1093/labmed/lmz017"
}

Janać, J., Zeljković, A., Jelić-Ivanović, Z., Dimitrijević-Srećković, V., Vekić, J., Miljković, M., Stefanović, A., Kotur-Stevuljević, J., Ivanišević, J.,& Spasojević-Kalimanovska, V.. (2020). Increased oxidized high-density lipoprotein/ high-density lipoprotein-cholesterol ratio as a potential indicator of disturbed metabolic health in overweight and obese individuals. in Lab Medicine
Oxford University Press., 51(1), 24-33.
https://doi.org/10.1093/labmed/lmz017

Janać J, Zeljković A, Jelić-Ivanović Z, Dimitrijević-Srećković V, Vekić J, Miljković M, Stefanović A, Kotur-Stevuljević J, Ivanišević J, Spasojević-Kalimanovska V. Increased oxidized high-density lipoprotein/ high-density lipoprotein-cholesterol ratio as a potential indicator of disturbed metabolic health in overweight and obese individuals. in Lab Medicine. 2020;51(1):24-33.
doi:10.1093/labmed/lmz017 .

Janać, Jelena, Zeljković, Aleksandra, Jelić-Ivanović, Zorana, Dimitrijević-Srećković, Vesna, Vekić, Jelena, Miljković, Milica, Stefanović, Aleksandra, Kotur-Stevuljević, Jelena, Ivanišević, Jasmina, Spasojević-Kalimanovska, Vesna, "Increased oxidized high-density lipoprotein/ high-density lipoprotein-cholesterol ratio as a potential indicator of disturbed metabolic health in overweight and obese individuals" in Lab Medicine, 51, no. 1 (2020):24-33,
https://doi.org/10.1093/labmed/lmz017 . .

TY  - JOUR
AU  - Janać, Jelena
AU  - Zeljković, Aleksandra
AU  - Jelić-Ivanović, Zorana
AU  - Dimitrijević-Srećković, Vesna
AU  - Miljković, Milica
AU  - Stefanović, Aleksandra
AU  - Munjas, Jelena
AU  - Vekić, Jelena
AU  - Kotur-Stevuljević, Jelena
AU  - Spasojević-Kalimanovska, Vesna
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3293
AB  - Background: Non-alcoholic fatty liver disease is a frequent ailment with known complications, including those within the cardiovascular system. Associations between several indicators of high-density lipoprotein metabolism and function with clinical and laboratory parameters for the assessment of fatty liver index, a surrogate marker of non-alcoholic fatty liver disease, were evaluated. Methods: The study comprised 130 patients classified according to fatty liver index values: fatty liver index  lt  30, fatty liver index 30–59 (the intermediate group) and fatty liver index ⩾ 60. Lecithin–cholesterol acyltransferase and cholesteryl ester transfer protein activities were determined. Paraoxonase 1 concentration and its activity, paraoxonase 3 concentration and high-density lipoprotein subclass distribution were assessed. Results: Increased lecithin–cholesterol acyltransferase activity correlated with increased fatty liver index (P  lt  0.001). Paraoxonase 3 concentration was lower in the fatty liver index ⩾ 60 group compared with the fatty liver index  lt  30 group (P  lt  0.05). Cholesteryl ester transfer protein activity, paraoxonase 1 concentration and its activity did not significantly differ across the fatty liver index groups. The relative proportion of small-sized high-density lipoprotein 3 subclass was higher in the fatty liver index ⩾ 60 group compared with the other two fatty liver index groups (P  lt  0.01). Lecithin–cholesterol acyltransferase activity positively associated with the fatty liver index ⩾ 60 group and remained significant after adjustment for other potential confounders. Only the triglyceride concentration remained significantly associated with lecithin–cholesterol acyltransferase activity when the parameters that constitute the fatty liver index equation were examined. Conclusions: Higher lecithin–cholesterol acyltransferase activity is associated with elevated fatty liver index values. Significant independent association between triglycerides and lecithin–cholesterol acyltransferase activity might indicate a role of hypertriglyceridaemia in alterations of lecithin–cholesterol acyltransferase activity in individuals with elevated fatty liver index.
PB  - Sage Publications Ltd
T2  - Annals of Clinical Biochemistry
T1  - The association between lecithin–cholesterol acyltransferase activity and fatty liver index
VL  - 56
IS  - 5
SP  - 583
EP  - 592
DO  - 10.1177/0004563219853596
ER  - 

@article{
author = "Janać, Jelena and Zeljković, Aleksandra and Jelić-Ivanović, Zorana and Dimitrijević-Srećković, Vesna and Miljković, Milica and Stefanović, Aleksandra and Munjas, Jelena and Vekić, Jelena and Kotur-Stevuljević, Jelena and Spasojević-Kalimanovska, Vesna",
year = "2019",
abstract = "Background: Non-alcoholic fatty liver disease is a frequent ailment with known complications, including those within the cardiovascular system. Associations between several indicators of high-density lipoprotein metabolism and function with clinical and laboratory parameters for the assessment of fatty liver index, a surrogate marker of non-alcoholic fatty liver disease, were evaluated. Methods: The study comprised 130 patients classified according to fatty liver index values: fatty liver index  lt  30, fatty liver index 30–59 (the intermediate group) and fatty liver index ⩾ 60. Lecithin–cholesterol acyltransferase and cholesteryl ester transfer protein activities were determined. Paraoxonase 1 concentration and its activity, paraoxonase 3 concentration and high-density lipoprotein subclass distribution were assessed. Results: Increased lecithin–cholesterol acyltransferase activity correlated with increased fatty liver index (P  lt  0.001). Paraoxonase 3 concentration was lower in the fatty liver index ⩾ 60 group compared with the fatty liver index  lt  30 group (P  lt  0.05). Cholesteryl ester transfer protein activity, paraoxonase 1 concentration and its activity did not significantly differ across the fatty liver index groups. The relative proportion of small-sized high-density lipoprotein 3 subclass was higher in the fatty liver index ⩾ 60 group compared with the other two fatty liver index groups (P  lt  0.01). Lecithin–cholesterol acyltransferase activity positively associated with the fatty liver index ⩾ 60 group and remained significant after adjustment for other potential confounders. Only the triglyceride concentration remained significantly associated with lecithin–cholesterol acyltransferase activity when the parameters that constitute the fatty liver index equation were examined. Conclusions: Higher lecithin–cholesterol acyltransferase activity is associated with elevated fatty liver index values. Significant independent association between triglycerides and lecithin–cholesterol acyltransferase activity might indicate a role of hypertriglyceridaemia in alterations of lecithin–cholesterol acyltransferase activity in individuals with elevated fatty liver index.",
publisher = "Sage Publications Ltd",
journal = "Annals of Clinical Biochemistry",
title = "The association between lecithin–cholesterol acyltransferase activity and fatty liver index",
volume = "56",
number = "5",
pages = "583-592",
doi = "10.1177/0004563219853596"
}

Janać, J., Zeljković, A., Jelić-Ivanović, Z., Dimitrijević-Srećković, V., Miljković, M., Stefanović, A., Munjas, J., Vekić, J., Kotur-Stevuljević, J.,& Spasojević-Kalimanovska, V.. (2019). The association between lecithin–cholesterol acyltransferase activity and fatty liver index. in Annals of Clinical Biochemistry
Sage Publications Ltd., 56(5), 583-592.
https://doi.org/10.1177/0004563219853596

Janać J, Zeljković A, Jelić-Ivanović Z, Dimitrijević-Srećković V, Miljković M, Stefanović A, Munjas J, Vekić J, Kotur-Stevuljević J, Spasojević-Kalimanovska V. The association between lecithin–cholesterol acyltransferase activity and fatty liver index. in Annals of Clinical Biochemistry. 2019;56(5):583-592.
doi:10.1177/0004563219853596 .

Janać, Jelena, Zeljković, Aleksandra, Jelić-Ivanović, Zorana, Dimitrijević-Srećković, Vesna, Miljković, Milica, Stefanović, Aleksandra, Munjas, Jelena, Vekić, Jelena, Kotur-Stevuljević, Jelena, Spasojević-Kalimanovska, Vesna, "The association between lecithin–cholesterol acyltransferase activity and fatty liver index" in Annals of Clinical Biochemistry, 56, no. 5 (2019):583-592,
https://doi.org/10.1177/0004563219853596 . .

TY  - JOUR
AU  - Dodevska, Margarita
AU  - Šobajić, Slađana
AU  - Đorđević, Predrag B.
AU  - Dimitrijević-Srećković, Vesna
AU  - Spasojević-Kalimanovska, Vesna
AU  - Đorđević, Brižita
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2569
AB  - Starting from the evidence-based health benefits that resistant starch (RS) shows when added to the diet, our aim in this study was to evaluate the effects of increased fibre intake with two different levels of RS coming from regular daily consumed foods on normalization of glycaemia within lifestyle intervention in the population with risk factors for developing diabetes. Study included 47 overweight and obese men and women with disordered glucoregulation and dyslipidaemia, aged between 45-74, divided into RS and Fibre group. Participants were subjected to the lifestyle and dietary intervention with low-fat and high-fibre (> 25 g/day) diet for 12 months and were offered two different dietary advices aimed at increasing total fibre intake in Fibre group and at increasing RS intake in RS group. The intake of macronutrients and total fibre was similar between groups at the end of the study, but achieved RS intake was two times higher in the RS group. Decrease in total cholesterol and non-HDL-cholesterol was more pronounced in RS group in comparison with Fibre group (p = 0.010, p = 0.031, respectively), whereas in Fibre group, a more pronounced effect on glucoregulation was observed: significant fall in glycaemia after 2-h oral glucose tolerance test (7.93 vs 6.96 mmol/L, p = 0.034). At the end of the study, RS-rich diet failed to affect glycaemic control in prediabetic obese individuals in contrast to the regular fibre-rich diet, which indicated that fibre profile could be an important determinant of the effect of dietary intervention.
PB  - Springer Heidelberg, Heidelberg
T2  - European Journal of Nutrition
T1  - Effects of total fibre or resistant starch-rich diets within lifestyle intervention in obese prediabetic adults
VL  - 55
IS  - 1
SP  - 127
EP  - 137
DO  - 10.1007/s00394-015-0831-3
ER  - 

@article{
author = "Dodevska, Margarita and Šobajić, Slađana and Đorđević, Predrag B. and Dimitrijević-Srećković, Vesna and Spasojević-Kalimanovska, Vesna and Đorđević, Brižita",
year = "2016",
abstract = "Starting from the evidence-based health benefits that resistant starch (RS) shows when added to the diet, our aim in this study was to evaluate the effects of increased fibre intake with two different levels of RS coming from regular daily consumed foods on normalization of glycaemia within lifestyle intervention in the population with risk factors for developing diabetes. Study included 47 overweight and obese men and women with disordered glucoregulation and dyslipidaemia, aged between 45-74, divided into RS and Fibre group. Participants were subjected to the lifestyle and dietary intervention with low-fat and high-fibre (> 25 g/day) diet for 12 months and were offered two different dietary advices aimed at increasing total fibre intake in Fibre group and at increasing RS intake in RS group. The intake of macronutrients and total fibre was similar between groups at the end of the study, but achieved RS intake was two times higher in the RS group. Decrease in total cholesterol and non-HDL-cholesterol was more pronounced in RS group in comparison with Fibre group (p = 0.010, p = 0.031, respectively), whereas in Fibre group, a more pronounced effect on glucoregulation was observed: significant fall in glycaemia after 2-h oral glucose tolerance test (7.93 vs 6.96 mmol/L, p = 0.034). At the end of the study, RS-rich diet failed to affect glycaemic control in prediabetic obese individuals in contrast to the regular fibre-rich diet, which indicated that fibre profile could be an important determinant of the effect of dietary intervention.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "European Journal of Nutrition",
title = "Effects of total fibre or resistant starch-rich diets within lifestyle intervention in obese prediabetic adults",
volume = "55",
number = "1",
pages = "127-137",
doi = "10.1007/s00394-015-0831-3"
}

Dodevska, M., Šobajić, S., Đorđević, P. B., Dimitrijević-Srećković, V., Spasojević-Kalimanovska, V.,& Đorđević, B.. (2016). Effects of total fibre or resistant starch-rich diets within lifestyle intervention in obese prediabetic adults. in European Journal of Nutrition
Springer Heidelberg, Heidelberg., 55(1), 127-137.
https://doi.org/10.1007/s00394-015-0831-3

Dodevska M, Šobajić S, Đorđević PB, Dimitrijević-Srećković V, Spasojević-Kalimanovska V, Đorđević B. Effects of total fibre or resistant starch-rich diets within lifestyle intervention in obese prediabetic adults. in European Journal of Nutrition. 2016;55(1):127-137.
doi:10.1007/s00394-015-0831-3 .

Dodevska, Margarita, Šobajić, Slađana, Đorđević, Predrag B., Dimitrijević-Srećković, Vesna, Spasojević-Kalimanovska, Vesna, Đorđević, Brižita, "Effects of total fibre or resistant starch-rich diets within lifestyle intervention in obese prediabetic adults" in European Journal of Nutrition, 55, no. 1 (2016):127-137,
https://doi.org/10.1007/s00394-015-0831-3 . .

TY  - CONF
AU  - Dimitrijević-Srećković, Vesna
AU  - Srecković, B.
AU  - Janeski, H.
AU  - Soldatović, Ivan
AU  - Janać, Jelena
AU  - Jelić-Ivanović, Zorana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2444
PB  - Elsevier Ireland Ltd, Clare
C3  - Atherosclerosis
T1  - Abdominal obesity responsible for depression and risk of early atherosclerosis in adolescents and youth
VL  - 241
IS  - 1
SP  - e167
EP  - e167
DO  - 10.1016/j.atherosclerosis.2015.04.859
ER  - 

@conference{
author = "Dimitrijević-Srećković, Vesna and Srecković, B. and Janeski, H. and Soldatović, Ivan and Janać, Jelena and Jelić-Ivanović, Zorana",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Atherosclerosis",
title = "Abdominal obesity responsible for depression and risk of early atherosclerosis in adolescents and youth",
volume = "241",
number = "1",
pages = "e167-e167",
doi = "10.1016/j.atherosclerosis.2015.04.859"
}

Dimitrijević-Srećković, V., Srecković, B., Janeski, H., Soldatović, I., Janać, J.,& Jelić-Ivanović, Z.. (2015). Abdominal obesity responsible for depression and risk of early atherosclerosis in adolescents and youth. in Atherosclerosis
Elsevier Ireland Ltd, Clare., 241(1), e167-e167.
https://doi.org/10.1016/j.atherosclerosis.2015.04.859

Dimitrijević-Srećković V, Srecković B, Janeski H, Soldatović I, Janać J, Jelić-Ivanović Z. Abdominal obesity responsible for depression and risk of early atherosclerosis in adolescents and youth. in Atherosclerosis. 2015;241(1):e167-e167.
doi:10.1016/j.atherosclerosis.2015.04.859 .

Dimitrijević-Srećković, Vesna, Srecković, B., Janeski, H., Soldatović, Ivan, Janać, Jelena, Jelić-Ivanović, Zorana, "Abdominal obesity responsible for depression and risk of early atherosclerosis in adolescents and youth" in Atherosclerosis, 241, no. 1 (2015):e167-e167,
https://doi.org/10.1016/j.atherosclerosis.2015.04.859 . .

TY  - CONF
AU  - Dimitrijević-Srećković, Vesna
AU  - Janeski, H.
AU  - Srecković, B.
AU  - Soldatović, Ivan
AU  - Janać, Jelena
AU  - Jelić-Ivanović, Zorana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2447
PB  - Elsevier Ireland Ltd, Clare
C3  - Atherosclerosis
T1  - Progression of abdominal obesity in youth followed by testosterone decrease leading to erectile dysfunction and risk of early atherosclerosis
VL  - 241
IS  - 1
SP  - e167
EP  - e167
DO  - 10.1016/j.atherosclerosis.2015.04.860
ER  - 

@conference{
author = "Dimitrijević-Srećković, Vesna and Janeski, H. and Srecković, B. and Soldatović, Ivan and Janać, Jelena and Jelić-Ivanović, Zorana",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Atherosclerosis",
title = "Progression of abdominal obesity in youth followed by testosterone decrease leading to erectile dysfunction and risk of early atherosclerosis",
volume = "241",
number = "1",
pages = "e167-e167",
doi = "10.1016/j.atherosclerosis.2015.04.860"
}

Dimitrijević-Srećković, V., Janeski, H., Srecković, B., Soldatović, I., Janać, J.,& Jelić-Ivanović, Z.. (2015). Progression of abdominal obesity in youth followed by testosterone decrease leading to erectile dysfunction and risk of early atherosclerosis. in Atherosclerosis
Elsevier Ireland Ltd, Clare., 241(1), e167-e167.
https://doi.org/10.1016/j.atherosclerosis.2015.04.860

Dimitrijević-Srećković V, Janeski H, Srecković B, Soldatović I, Janać J, Jelić-Ivanović Z. Progression of abdominal obesity in youth followed by testosterone decrease leading to erectile dysfunction and risk of early atherosclerosis. in Atherosclerosis. 2015;241(1):e167-e167.
doi:10.1016/j.atherosclerosis.2015.04.860 .

Dimitrijević-Srećković, Vesna, Janeski, H., Srecković, B., Soldatović, Ivan, Janać, Jelena, Jelić-Ivanović, Zorana, "Progression of abdominal obesity in youth followed by testosterone decrease leading to erectile dysfunction and risk of early atherosclerosis" in Atherosclerosis, 241, no. 1 (2015):e167-e167,
https://doi.org/10.1016/j.atherosclerosis.2015.04.860 . .

TY  - JOUR
AU  - Dodevska, Margarita
AU  - Đorđević, Brižita
AU  - Šobajić, Slađana
AU  - Miletić, Ivanka
AU  - Đorđević, Predrag B.
AU  - Dimitrijević-Srećković, Vesna
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1896
AB  - The typical Serbian diet is characterised by high intake of cereal products and also legumes are often used. The content of total fibre as well as certain fibre fractions was determined in cereals, cereal products, and cooked legumes. The content of total fibre in cooked cereals and cereal products ranged from 2.5 to 20.8 g/100 g, and in cooked legumes from 14.0 to 24.5 g/100 g (on dry matter basis). Distribution of analysed fibre fractions and their quantities differed significantly depending on food groups. Fructans and arabinoxylans were the most significant fibre fractions in rye flakes, and beta-glucan in oat flakes, cellulose and resistant starch were present in significant amounts in peas and kidney beans. When the size of regular food portions was taken into consideration, the best sources of total dietary fibre were peas and kidney beans (more than 11 g/serving). The same foods were the best sources of cellulose (4.98 and 3.56 g/serving) and resistant starch (3.90 and 2.83 g/serving). High intake of arabinoxylans and fructans could be accomplished with cooked wheat (3.20 g and 1.60 g/serving, respectively). Oat (1.39 g/serving) and barley flakes (1.30 g/serving) can be recommended as the best sources of beta-glucan.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - Characterisation of dietary fibre components in cereals and legumes used in Serbian diet
VL  - 141
IS  - 3
SP  - 1624
EP  - 1629
DO  - 10.1016/j.foodchem.2013.05.078
ER  - 

@article{
author = "Dodevska, Margarita and Đorđević, Brižita and Šobajić, Slađana and Miletić, Ivanka and Đorđević, Predrag B. and Dimitrijević-Srećković, Vesna",
year = "2013",
abstract = "The typical Serbian diet is characterised by high intake of cereal products and also legumes are often used. The content of total fibre as well as certain fibre fractions was determined in cereals, cereal products, and cooked legumes. The content of total fibre in cooked cereals and cereal products ranged from 2.5 to 20.8 g/100 g, and in cooked legumes from 14.0 to 24.5 g/100 g (on dry matter basis). Distribution of analysed fibre fractions and their quantities differed significantly depending on food groups. Fructans and arabinoxylans were the most significant fibre fractions in rye flakes, and beta-glucan in oat flakes, cellulose and resistant starch were present in significant amounts in peas and kidney beans. When the size of regular food portions was taken into consideration, the best sources of total dietary fibre were peas and kidney beans (more than 11 g/serving). The same foods were the best sources of cellulose (4.98 and 3.56 g/serving) and resistant starch (3.90 and 2.83 g/serving). High intake of arabinoxylans and fructans could be accomplished with cooked wheat (3.20 g and 1.60 g/serving, respectively). Oat (1.39 g/serving) and barley flakes (1.30 g/serving) can be recommended as the best sources of beta-glucan.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "Characterisation of dietary fibre components in cereals and legumes used in Serbian diet",
volume = "141",
number = "3",
pages = "1624-1629",
doi = "10.1016/j.foodchem.2013.05.078"
}

Dodevska, M., Đorđević, B., Šobajić, S., Miletić, I., Đorđević, P. B.,& Dimitrijević-Srećković, V.. (2013). Characterisation of dietary fibre components in cereals and legumes used in Serbian diet. in Food Chemistry
Elsevier Sci Ltd, Oxford., 141(3), 1624-1629.
https://doi.org/10.1016/j.foodchem.2013.05.078

Dodevska M, Đorđević B, Šobajić S, Miletić I, Đorđević PB, Dimitrijević-Srećković V. Characterisation of dietary fibre components in cereals and legumes used in Serbian diet. in Food Chemistry. 2013;141(3):1624-1629.
doi:10.1016/j.foodchem.2013.05.078 .

Dodevska, Margarita, Đorđević, Brižita, Šobajić, Slađana, Miletić, Ivanka, Đorđević, Predrag B., Dimitrijević-Srećković, Vesna, "Characterisation of dietary fibre components in cereals and legumes used in Serbian diet" in Food Chemistry, 141, no. 3 (2013):1624-1629,
https://doi.org/10.1016/j.foodchem.2013.05.078 . .