TY  - JOUR
AU  - Cerović, Aleksandra
AU  - Miletić, Ivanka
AU  - Blagojević, Duško
AU  - Šobajić, Slađana
AU  - Vasiljevska, Milijana
AU  - Poznanić, Milica
AU  - Radusinović, M.
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1069
AB  - This study examined the influence of low, adequate and high dietary zinc intake on the growth and metabolic interactions between zinc, copper and iron in different Mongolian gerbil (Meriones unguiculatus) tissues. Animals were fed a basal diet (for 3 wk) containing a low-zinc level (8 mg/ kg diet, LZ-group), adequate zinc level (25 mg/kg diet, AZ-group) and saturated zinc level (38 mg/ kg diet, SZ-group). After comparing the body weight of gerbils, the present study demonstrated that the LZ-group (51.68 g +/- 3.35) showed growth retardation, contrary to the AZ- and SZ-groups (58.03 g +/- 2.18 and 62.35 g +/- 2.04, respectively). Concentrations of zinc in the liver, kidneys and testes in the LZ-group (41.28, 19.58, 22.55 mg/kg, respectively) were significantly lower than in the AZ-group (57.27, 23.73, 28.79 mg/kg, respectively) and the SZ-group (73.06, 30.07, 34.52 mg/kg, respectively). Results also showed that copper and iron concentrations in the kidney, heart and liver were significantly higher in the LZ-group (Cu 11.45, 7.01, 7.95 mg/kg; Fe 116.19, 126.07, 299.47 mg/kg) than in the AZ-group (Cu 8.72, 5.6, 6.5 mg/kg; Fe 97.27, 97.27, 250.25 mg/kg) and the SZ-group (Cu 6.48, 4.15, 4.8 mg/kg; Fe 74.95, 77.95, 200.27 mg/kg). There was an increase of testis copper concentration in the LZ-group (4.9 mg/kg) compared to the AZ- and SZ-groups (3.99 and 3.05 mg/kg, respectively), and there was no significant difference in testis iron concentration between animals in different diet groups. These results showed that a low-zinc diet had negative effects on growth and the concentration of zinc in the kidneys, liver and testes. This also affected homeostasis of copper and iron by increasing its distribution in the kidneys, liver and heart tissue. However, in testes only copper concentration was increased.
PB  - Veterinarni A Farmaceuticka Univerzita Brno, Brno
T2  - Acta Veterinaria Brno
T1  - Effects of low, adequate and high dietary zinc intake on metabolic interactions between zinc, copper and iron in different mongolian gerbil tissues
VL  - 77
IS  - 1
SP  - 17
EP  - 23
DO  - 10.2754/avb200877010017
ER  - 

@article{
author = "Cerović, Aleksandra and Miletić, Ivanka and Blagojević, Duško and Šobajić, Slađana and Vasiljevska, Milijana and Poznanić, Milica and Radusinović, M.",
year = "2008",
abstract = "This study examined the influence of low, adequate and high dietary zinc intake on the growth and metabolic interactions between zinc, copper and iron in different Mongolian gerbil (Meriones unguiculatus) tissues. Animals were fed a basal diet (for 3 wk) containing a low-zinc level (8 mg/ kg diet, LZ-group), adequate zinc level (25 mg/kg diet, AZ-group) and saturated zinc level (38 mg/ kg diet, SZ-group). After comparing the body weight of gerbils, the present study demonstrated that the LZ-group (51.68 g +/- 3.35) showed growth retardation, contrary to the AZ- and SZ-groups (58.03 g +/- 2.18 and 62.35 g +/- 2.04, respectively). Concentrations of zinc in the liver, kidneys and testes in the LZ-group (41.28, 19.58, 22.55 mg/kg, respectively) were significantly lower than in the AZ-group (57.27, 23.73, 28.79 mg/kg, respectively) and the SZ-group (73.06, 30.07, 34.52 mg/kg, respectively). Results also showed that copper and iron concentrations in the kidney, heart and liver were significantly higher in the LZ-group (Cu 11.45, 7.01, 7.95 mg/kg; Fe 116.19, 126.07, 299.47 mg/kg) than in the AZ-group (Cu 8.72, 5.6, 6.5 mg/kg; Fe 97.27, 97.27, 250.25 mg/kg) and the SZ-group (Cu 6.48, 4.15, 4.8 mg/kg; Fe 74.95, 77.95, 200.27 mg/kg). There was an increase of testis copper concentration in the LZ-group (4.9 mg/kg) compared to the AZ- and SZ-groups (3.99 and 3.05 mg/kg, respectively), and there was no significant difference in testis iron concentration between animals in different diet groups. These results showed that a low-zinc diet had negative effects on growth and the concentration of zinc in the kidneys, liver and testes. This also affected homeostasis of copper and iron by increasing its distribution in the kidneys, liver and heart tissue. However, in testes only copper concentration was increased.",
publisher = "Veterinarni A Farmaceuticka Univerzita Brno, Brno",
journal = "Acta Veterinaria Brno",
title = "Effects of low, adequate and high dietary zinc intake on metabolic interactions between zinc, copper and iron in different mongolian gerbil tissues",
volume = "77",
number = "1",
pages = "17-23",
doi = "10.2754/avb200877010017"
}

Cerović, A., Miletić, I., Blagojević, D., Šobajić, S., Vasiljevska, M., Poznanić, M.,& Radusinović, M.. (2008). Effects of low, adequate and high dietary zinc intake on metabolic interactions between zinc, copper and iron in different mongolian gerbil tissues. in Acta Veterinaria Brno
Veterinarni A Farmaceuticka Univerzita Brno, Brno., 77(1), 17-23.
https://doi.org/10.2754/avb200877010017

Cerović A, Miletić I, Blagojević D, Šobajić S, Vasiljevska M, Poznanić M, Radusinović M. Effects of low, adequate and high dietary zinc intake on metabolic interactions between zinc, copper and iron in different mongolian gerbil tissues. in Acta Veterinaria Brno. 2008;77(1):17-23.
doi:10.2754/avb200877010017 .

Cerović, Aleksandra, Miletić, Ivanka, Blagojević, Duško, Šobajić, Slađana, Vasiljevska, Milijana, Poznanić, Milica, Radusinović, M., "Effects of low, adequate and high dietary zinc intake on metabolic interactions between zinc, copper and iron in different mongolian gerbil tissues" in Acta Veterinaria Brno, 77, no. 1 (2008):17-23,
https://doi.org/10.2754/avb200877010017 . .

TY  - JOUR
AU  - Cerović, Aleksandra
AU  - Miletić, Ivanka
AU  - Šobajić, Slađana
AU  - Blagojević, Duško
AU  - Radusinović, Miodrag
AU  - El-Sohemy, Ahmed
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/927
AB  - Zinc is an important mineral that is required for normal bone development. However, the direct effects of zinc on the mineralization of bone cells of human origin are not clear. The objective of this study was to determine the effects of zinc on the differentiation of SaOS-2 human osteoblast-like cells and the formation of mineralized bone nodules. Cells were cultured for 8 d and then transferred to zinc-free medium and treated with varying concentrations (0-50 mu M) of zinc. Alkaline phosphatase (ALP) activity was used as a measure of osteoblast differentiation, and bone nodules were detected by von Kossa staining. After 4, 6, and 8 d of treatment, zinc increased ALP activity at 1 and 10 mu M, but decreased activity at 50 mu M. After 9 d of treatment, zinc increased both the number and area of mineralized bone nodules at low concentrations (1 and 10 mu M), but decreased both at higher concentrations (25 and 50 mu M). These findings demonstrate that zinc has biphasic effects on the differentiation and mineralization of human osteoblast-like cells.
PB  - Humana Press Inc, Totowa
T2  - Biological Trace Element Research
T1  - Effects of zinc on the mineralization of bone nodules from human osteoblast-like cells
VL  - 116
IS  - 1
SP  - 61
EP  - 71
DO  - 10.1007/BF02685919
ER  - 

@article{
author = "Cerović, Aleksandra and Miletić, Ivanka and Šobajić, Slađana and Blagojević, Duško and Radusinović, Miodrag and El-Sohemy, Ahmed",
year = "2007",
abstract = "Zinc is an important mineral that is required for normal bone development. However, the direct effects of zinc on the mineralization of bone cells of human origin are not clear. The objective of this study was to determine the effects of zinc on the differentiation of SaOS-2 human osteoblast-like cells and the formation of mineralized bone nodules. Cells were cultured for 8 d and then transferred to zinc-free medium and treated with varying concentrations (0-50 mu M) of zinc. Alkaline phosphatase (ALP) activity was used as a measure of osteoblast differentiation, and bone nodules were detected by von Kossa staining. After 4, 6, and 8 d of treatment, zinc increased ALP activity at 1 and 10 mu M, but decreased activity at 50 mu M. After 9 d of treatment, zinc increased both the number and area of mineralized bone nodules at low concentrations (1 and 10 mu M), but decreased both at higher concentrations (25 and 50 mu M). These findings demonstrate that zinc has biphasic effects on the differentiation and mineralization of human osteoblast-like cells.",
publisher = "Humana Press Inc, Totowa",
journal = "Biological Trace Element Research",
title = "Effects of zinc on the mineralization of bone nodules from human osteoblast-like cells",
volume = "116",
number = "1",
pages = "61-71",
doi = "10.1007/BF02685919"
}

Cerović, A., Miletić, I., Šobajić, S., Blagojević, D., Radusinović, M.,& El-Sohemy, A.. (2007). Effects of zinc on the mineralization of bone nodules from human osteoblast-like cells. in Biological Trace Element Research
Humana Press Inc, Totowa., 116(1), 61-71.
https://doi.org/10.1007/BF02685919

Cerović A, Miletić I, Šobajić S, Blagojević D, Radusinović M, El-Sohemy A. Effects of zinc on the mineralization of bone nodules from human osteoblast-like cells. in Biological Trace Element Research. 2007;116(1):61-71.
doi:10.1007/BF02685919 .

Cerović, Aleksandra, Miletić, Ivanka, Šobajić, Slađana, Blagojević, Duško, Radusinović, Miodrag, El-Sohemy, Ahmed, "Effects of zinc on the mineralization of bone nodules from human osteoblast-like cells" in Biological Trace Element Research, 116, no. 1 (2007):61-71,
https://doi.org/10.1007/BF02685919 . .

TY  - JOUR
AU  - Cerović, Aleksandra
AU  - Miletić, Ivanka
AU  - Konić-Ristić, Aleksandra
AU  - Baralić, Ivana
AU  - Đorđević, Brižita
AU  - Đuričić, Ivana
AU  - Radusinović, M
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/869
AB  - The aim of present study was to assess the effects and safety of a dry Phaseoli vulgari pericarpium (PVP) extract on postprandial glycemia in healthy participants. A randomized crossover experiment where participants received either PVP extract or placebo. Chemical compounds in dry extract were assessed by established methods. Eighteen healthy participants (9 male and 9 female) aged 29+/-4,8 years, body mass index (BMI) 23+/-3,7 kg/m(2) were recruited among students and staff at the Faculty of Pharmacy, University of Belgrade. All participants were able to follow the study protocol without difficulty. The participants received either PVP extract or placebo 30 minutes before a 50g oral glucose tolerance test (OGTT). The protocol followed the guidelines for the OGTT with blood samples drawn at 0, 15, 30, 60, 90 and 120 min. This study demonstrated that there was no significantly effect of the PVP extract on incremental blood glucose (IBG) and their areas under the curve (AUC) neither male nor female participants. However, IBG together with AUC changes were significantly lower in male compared with female participants in treated and untreated groups. The presence of chrome, soluble fiber, vitamin C, protein, glucose and lectins were also quantified. The applied amount of PVP extract was unable to produce the postprandial hypoglycemia. We assumed that amounts of chrome, soluble fiber, vitamin C which have beneficial effects on diabetes treatment were sufficient to produce hypoglycemia.
PB  - Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
T2  - Bosnian Journal of Basic Medical Sciences
T1  - The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.
VL  - 6
IS  - 3
SP  - 28
EP  - 33
UR  - https://hdl.handle.net/21.15107/rcub_farfar_869
ER  - 

@article{
author = "Cerović, Aleksandra and Miletić, Ivanka and Konić-Ristić, Aleksandra and Baralić, Ivana and Đorđević, Brižita and Đuričić, Ivana and Radusinović, M",
year = "2006",
abstract = "The aim of present study was to assess the effects and safety of a dry Phaseoli vulgari pericarpium (PVP) extract on postprandial glycemia in healthy participants. A randomized crossover experiment where participants received either PVP extract or placebo. Chemical compounds in dry extract were assessed by established methods. Eighteen healthy participants (9 male and 9 female) aged 29+/-4,8 years, body mass index (BMI) 23+/-3,7 kg/m(2) were recruited among students and staff at the Faculty of Pharmacy, University of Belgrade. All participants were able to follow the study protocol without difficulty. The participants received either PVP extract or placebo 30 minutes before a 50g oral glucose tolerance test (OGTT). The protocol followed the guidelines for the OGTT with blood samples drawn at 0, 15, 30, 60, 90 and 120 min. This study demonstrated that there was no significantly effect of the PVP extract on incremental blood glucose (IBG) and their areas under the curve (AUC) neither male nor female participants. However, IBG together with AUC changes were significantly lower in male compared with female participants in treated and untreated groups. The presence of chrome, soluble fiber, vitamin C, protein, glucose and lectins were also quantified. The applied amount of PVP extract was unable to produce the postprandial hypoglycemia. We assumed that amounts of chrome, soluble fiber, vitamin C which have beneficial effects on diabetes treatment were sufficient to produce hypoglycemia.",
publisher = "Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina",
journal = "Bosnian Journal of Basic Medical Sciences",
title = "The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.",
volume = "6",
number = "3",
pages = "28-33",
url = "https://hdl.handle.net/21.15107/rcub_farfar_869"
}

Cerović, A., Miletić, I., Konić-Ristić, A., Baralić, I., Đorđević, B., Đuričić, I.,& Radusinović, M.. (2006). The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.. in Bosnian Journal of Basic Medical Sciences
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina., 6(3), 28-33.
https://hdl.handle.net/21.15107/rcub_farfar_869

Cerović A, Miletić I, Konić-Ristić A, Baralić I, Đorđević B, Đuričić I, Radusinović M. The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.. in Bosnian Journal of Basic Medical Sciences. 2006;6(3):28-33.
https://hdl.handle.net/21.15107/rcub_farfar_869 .

Cerović, Aleksandra, Miletić, Ivanka, Konić-Ristić, Aleksandra, Baralić, Ivana, Đorđević, Brižita, Đuričić, Ivana, Radusinović, M, "The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject." in Bosnian Journal of Basic Medical Sciences, 6, no. 3 (2006):28-33,
https://hdl.handle.net/21.15107/rcub_farfar_869 .

TY  - JOUR
AU  - Cerović, Aleksandra
AU  - Miletić, Ivanka
AU  - Šobajić, Slađana
AU  - Blagojević, Duško
AU  - Jones, David R.
AU  - Poznanić, Milica
AU  - Radusinović, Miodrag
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/707
AB  - The aim of this work was to explore the effects of a low- and high-zinc diet and vitamin A on the distribution of fatty acids in chylomicrons. Mongolian Gerbils were fed a basal diet (for 3 wk) containing 8 or 38 mg zinc/kg of feed (low-zinc group [termed LZ group] and saturated zinc group [termed SZ group], respectively). The following day, the animals were given sunflower oil containing 50 nmol vitamin A. The results showed that the concentration of zinc in blood plasma was similar in both groups. The amount of plasma chylomicrons was lower in the LZ group than in the SZ group (p  lt  0.001). The concentration of retinol in blood plasma was lower in the LZ group than in the SZ group (p  lt  0.01). However, the results demonstrated an increase in the blood plasma retinol concentration in the LZ group compared to the SZ group when calculated per milligram of plasma chylomicrons (p  lt  0.01). In plasma chylomicrons, fatty acids corresponding to 16:0, 16:1, 17:0, 17:1, 18:0, 18:1, 18:2, 18:3, 20:0, 21:0, and 20:4 were detected. The fatty acid distribution was similar in both groups. There was no major difference in the concentration of fatty acids in plasma chylomicrons between both experimental groups, except for 20:4 (a lower amount was found in the SZ group). Our results show that dietary zinc influences both the amount of chylomicrons in blood plasma and the concentrations of retinol and arachidonic acid in chylomicrons.
PB  - Humana Press Inc, Totowa
T2  - Biological Trace Element Research
T1  - Effect of dietary zinc on the levels and distribution of fatty acids and vitamin A in blood plasma chylomicrons
VL  - 112
IS  - 2
SP  - 145
EP  - 158
DO  - 10.1385/BTER:112:2:145
ER  - 

@article{
author = "Cerović, Aleksandra and Miletić, Ivanka and Šobajić, Slađana and Blagojević, Duško and Jones, David R. and Poznanić, Milica and Radusinović, Miodrag",
year = "2006",
abstract = "The aim of this work was to explore the effects of a low- and high-zinc diet and vitamin A on the distribution of fatty acids in chylomicrons. Mongolian Gerbils were fed a basal diet (for 3 wk) containing 8 or 38 mg zinc/kg of feed (low-zinc group [termed LZ group] and saturated zinc group [termed SZ group], respectively). The following day, the animals were given sunflower oil containing 50 nmol vitamin A. The results showed that the concentration of zinc in blood plasma was similar in both groups. The amount of plasma chylomicrons was lower in the LZ group than in the SZ group (p  lt  0.001). The concentration of retinol in blood plasma was lower in the LZ group than in the SZ group (p  lt  0.01). However, the results demonstrated an increase in the blood plasma retinol concentration in the LZ group compared to the SZ group when calculated per milligram of plasma chylomicrons (p  lt  0.01). In plasma chylomicrons, fatty acids corresponding to 16:0, 16:1, 17:0, 17:1, 18:0, 18:1, 18:2, 18:3, 20:0, 21:0, and 20:4 were detected. The fatty acid distribution was similar in both groups. There was no major difference in the concentration of fatty acids in plasma chylomicrons between both experimental groups, except for 20:4 (a lower amount was found in the SZ group). Our results show that dietary zinc influences both the amount of chylomicrons in blood plasma and the concentrations of retinol and arachidonic acid in chylomicrons.",
publisher = "Humana Press Inc, Totowa",
journal = "Biological Trace Element Research",
title = "Effect of dietary zinc on the levels and distribution of fatty acids and vitamin A in blood plasma chylomicrons",
volume = "112",
number = "2",
pages = "145-158",
doi = "10.1385/BTER:112:2:145"
}

Cerović, A., Miletić, I., Šobajić, S., Blagojević, D., Jones, D. R., Poznanić, M.,& Radusinović, M.. (2006). Effect of dietary zinc on the levels and distribution of fatty acids and vitamin A in blood plasma chylomicrons. in Biological Trace Element Research
Humana Press Inc, Totowa., 112(2), 145-158.
https://doi.org/10.1385/BTER:112:2:145

Cerović A, Miletić I, Šobajić S, Blagojević D, Jones DR, Poznanić M, Radusinović M. Effect of dietary zinc on the levels and distribution of fatty acids and vitamin A in blood plasma chylomicrons. in Biological Trace Element Research. 2006;112(2):145-158.
doi:10.1385/BTER:112:2:145 .

Cerović, Aleksandra, Miletić, Ivanka, Šobajić, Slađana, Blagojević, Duško, Jones, David R., Poznanić, Milica, Radusinović, Miodrag, "Effect of dietary zinc on the levels and distribution of fatty acids and vitamin A in blood plasma chylomicrons" in Biological Trace Element Research, 112, no. 2 (2006):145-158,
https://doi.org/10.1385/BTER:112:2:145 . .

TY  - JOUR
AU  - Cerović, Aleksandra
AU  - Miletić, Ivanka
AU  - Blagojević, Duško
AU  - Šobajić, Slađana
AU  - Čolić, Miodrag
AU  - Vasiljevska, Milijana
AU  - Poznanić, Milica
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/652
AB  - The effect of dietary zinc on the distribution of fatty acids in blood plasma chylomicrons was studied. The experiment was performed on male Mongolian Gerbils, fed ad libitum for 3 weeks with standard diet, containing 8 or 38 mg of Zn per kg of food (low zinc diet group, LZ, and saturated zinc diet group, SZ, respectivelly). At the 21st day gerbils were given sunflower oil by gavage. After 2.5 hours, blood was collected from abdominal vein, and samples were pooled (five animals per one sample). Chylomicron fractions were isolated by ultracentrifugation and mass of dried chylomicrons was measured. Fatty acid composition was analyzed by gas-liquid chromatography. Significantly higher amount of chylomicrons in blood plasma of SZ than in LZ group was found. In chylomicrons, following fatty acids were found: 16:0, 16:1, 17:0, 17:1, 18:0, 18:1, 18:2, 18:3, 20:0, 21:0 and 20:4. The amount of individual fatty acids in chylomicrons in both groups was similar, except 20:4 where lower amount in SZ group was found. Zinc diet did not affect fatty acid distribution in chylomicrons of both groups. Animals fed with zinc saturated diet had higher amount of fatty acids in blood plasma. Observed results suggest that dietary zinc influences the quantity of fatty acids absorption but not its distribution in chylomicrons.
AB  - Ispitivan je efekat unosa dijetarnog cinka na distribuciju masnih kiselina u hilomikronima plazme. Eksperiment je rađen na mužjacima gerbila, hranjenim standardnom dijetom, ad libitum, u toku 3 nedelje hrana je sadržala 8 ili 38 mg cinka po kg hrane (grupa sa smanjenim unosom cinka, LZ i grupa sa povećanim unosom cinka, SZ, respektivno). Dvadeset prvog dana, životinjama je dato suncokretovo ulje sondom. Nakon 2,5 časa, krv je uzimana iz abdominalne vene i uzorci su pulovani (5 životinja za jedan uzorak). Hilomikronske frakcije su izolovane ultracentrifugiranjem i merena je masa suvih hilomikrona. Masnokiselinski sastav lipida u hilomikronima je određivan gasno-tečnom hromatografijom. Nađena je značajno veća količina hilomikrona u plazmi SZ grupe nego u LZ grupi. U hilomikronima su nađene sledeće masne kiseline: 16:0, 16:1, 17:0, 17:1, 18:0, 18:1, 18:2, 18:3, 20:0, 21:0 i 20:4. Zastupljenost pojedinačnih masnih kiselina u hilomikronima obe grupe bila je slična, izuzev za 20:4 gde je izmerena niža količina u SZ grupi. Ishrana cinkom ne utiče na distribuciju većine masnih kiselina u hilomikronima. Dobijeni rezultati ukazuju da cink utiče na metabolizam masti i to u delu formiranja hilomikrona, ali je uticaj ograničen na količinu formiranih hilomikrona, ali ne i distribuciju pojedinih masnih kiselina u hilomikronima.
PB  - Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd
T2  - Jugoslovenska medicinska biohemija
T1  - The effect of zinc diet on distribution of fatty acid in blood plasma chylomicrons
T1  - Efekat ishrane cinkom na distribuciju masnih kiselina u hilomikronima plazme
VL  - 24
IS  - 1
SP  - 15
EP  - 20
DO  - 10.2298/JMH0501015C
ER  - 

@article{
author = "Cerović, Aleksandra and Miletić, Ivanka and Blagojević, Duško and Šobajić, Slađana and Čolić, Miodrag and Vasiljevska, Milijana and Poznanić, Milica",
year = "2005",
abstract = "The effect of dietary zinc on the distribution of fatty acids in blood plasma chylomicrons was studied. The experiment was performed on male Mongolian Gerbils, fed ad libitum for 3 weeks with standard diet, containing 8 or 38 mg of Zn per kg of food (low zinc diet group, LZ, and saturated zinc diet group, SZ, respectivelly). At the 21st day gerbils were given sunflower oil by gavage. After 2.5 hours, blood was collected from abdominal vein, and samples were pooled (five animals per one sample). Chylomicron fractions were isolated by ultracentrifugation and mass of dried chylomicrons was measured. Fatty acid composition was analyzed by gas-liquid chromatography. Significantly higher amount of chylomicrons in blood plasma of SZ than in LZ group was found. In chylomicrons, following fatty acids were found: 16:0, 16:1, 17:0, 17:1, 18:0, 18:1, 18:2, 18:3, 20:0, 21:0 and 20:4. The amount of individual fatty acids in chylomicrons in both groups was similar, except 20:4 where lower amount in SZ group was found. Zinc diet did not affect fatty acid distribution in chylomicrons of both groups. Animals fed with zinc saturated diet had higher amount of fatty acids in blood plasma. Observed results suggest that dietary zinc influences the quantity of fatty acids absorption but not its distribution in chylomicrons., Ispitivan je efekat unosa dijetarnog cinka na distribuciju masnih kiselina u hilomikronima plazme. Eksperiment je rađen na mužjacima gerbila, hranjenim standardnom dijetom, ad libitum, u toku 3 nedelje hrana je sadržala 8 ili 38 mg cinka po kg hrane (grupa sa smanjenim unosom cinka, LZ i grupa sa povećanim unosom cinka, SZ, respektivno). Dvadeset prvog dana, životinjama je dato suncokretovo ulje sondom. Nakon 2,5 časa, krv je uzimana iz abdominalne vene i uzorci su pulovani (5 životinja za jedan uzorak). Hilomikronske frakcije su izolovane ultracentrifugiranjem i merena je masa suvih hilomikrona. Masnokiselinski sastav lipida u hilomikronima je određivan gasno-tečnom hromatografijom. Nađena je značajno veća količina hilomikrona u plazmi SZ grupe nego u LZ grupi. U hilomikronima su nađene sledeće masne kiseline: 16:0, 16:1, 17:0, 17:1, 18:0, 18:1, 18:2, 18:3, 20:0, 21:0 i 20:4. Zastupljenost pojedinačnih masnih kiselina u hilomikronima obe grupe bila je slična, izuzev za 20:4 gde je izmerena niža količina u SZ grupi. Ishrana cinkom ne utiče na distribuciju većine masnih kiselina u hilomikronima. Dobijeni rezultati ukazuju da cink utiče na metabolizam masti i to u delu formiranja hilomikrona, ali je uticaj ograničen na količinu formiranih hilomikrona, ali ne i distribuciju pojedinih masnih kiselina u hilomikronima.",
publisher = "Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd",
journal = "Jugoslovenska medicinska biohemija",
title = "The effect of zinc diet on distribution of fatty acid in blood plasma chylomicrons, Efekat ishrane cinkom na distribuciju masnih kiselina u hilomikronima plazme",
volume = "24",
number = "1",
pages = "15-20",
doi = "10.2298/JMH0501015C"
}

Cerović, A., Miletić, I., Blagojević, D., Šobajić, S., Čolić, M., Vasiljevska, M.,& Poznanić, M.. (2005). The effect of zinc diet on distribution of fatty acid in blood plasma chylomicrons. in Jugoslovenska medicinska biohemija
Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd., 24(1), 15-20.
https://doi.org/10.2298/JMH0501015C

Cerović A, Miletić I, Blagojević D, Šobajić S, Čolić M, Vasiljevska M, Poznanić M. The effect of zinc diet on distribution of fatty acid in blood plasma chylomicrons. in Jugoslovenska medicinska biohemija. 2005;24(1):15-20.
doi:10.2298/JMH0501015C .

Cerović, Aleksandra, Miletić, Ivanka, Blagojević, Duško, Šobajić, Slađana, Čolić, Miodrag, Vasiljevska, Milijana, Poznanić, Milica, "The effect of zinc diet on distribution of fatty acid in blood plasma chylomicrons" in Jugoslovenska medicinska biohemija, 24, no. 1 (2005):15-20,
https://doi.org/10.2298/JMH0501015C . .

TY  - JOUR
AU  - Tepić, Aleksandra N.
AU  - Vujičić, Biserka L.
AU  - Cerović, Aleksandra
AU  - Đorđević, Brižita
PY  - 2004
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/561
AB  - The interest in diabetic gelatin products has been on the permanent increase due to a higher number of the diseased in our region. The products currently offered mainly derive from the import and thus are expensive for most consumers. Therefore, diabetic gelatin products of proper quality and cheaper as compared to the imported products should be produced in the local factories. Basic chemical content of the raspberry as a raw material for raspberry marmalade was studied in the paper. The first stage included the production of marmalade under laboratory conditions. Out of the total of 20 points, the sensory estimate accounted for 17.13. As to improve sensory properties and select the best reception, three new marmalades with differing fruit share and sweeteners were produced in the second stage. Marmalades were also assessed sensory. The best mark was recorded with marmalade produced in compliance to reception 4 (40% of fruits and 30% of fructose). The chemical content was analyzed for this marmalade, and the energetic value determined (558.92 kJ/100 g). The colors of the raw material and finished products were compared instrumentally, i.e. via assessing surface color with three stimuli photoelectrical color-meter. Microbiological value, along with the content of heavy metals in the best estimated marmalade satisfied the requirements of the existing legal rules.
AB  - Ponuda proizvoda namenjenih specijalnoj grupi potrošača - dijabetičarima je veoma oskudna. Asortiman proizvoda je mali, a cene relativno visoke za većinu potrošača. Iz ovih razloga nametnula se potreba za proizvodnjom dijabetičarskih želiranih proizvoda. Proizvedena je dijabetičarska marmelada od maline u laboratorijskim uslovima. U sirovini su određeni pH suva materija i frakcije pektinskih materija. Na osnovu senzorne ocene od više receptura odabrana je najpovoljnija. U gotovom proizvodu urađena je mikrobiološka analiza,hemijski sastav (pH, suva materija, šećeri, vitamin C mineralne materije, teški metali), površinska boja i energetska vrednost. Rezultati pokazuju da je dobijen proizvod vrhunskog kvaliteta.
PB  - Naučno voćarsko društvo Srbije, Čačak
T2  - Jugoslovensko voćarstvo
T1  - Raspberry marmalade for diabetics
T1  - Marmelada od maline za dijabetičare
VL  - 38
IS  - 147-148
SP  - 221
EP  - 228
UR  - https://hdl.handle.net/21.15107/rcub_farfar_561
ER  - 

@article{
author = "Tepić, Aleksandra N. and Vujičić, Biserka L. and Cerović, Aleksandra and Đorđević, Brižita",
year = "2004",
abstract = "The interest in diabetic gelatin products has been on the permanent increase due to a higher number of the diseased in our region. The products currently offered mainly derive from the import and thus are expensive for most consumers. Therefore, diabetic gelatin products of proper quality and cheaper as compared to the imported products should be produced in the local factories. Basic chemical content of the raspberry as a raw material for raspberry marmalade was studied in the paper. The first stage included the production of marmalade under laboratory conditions. Out of the total of 20 points, the sensory estimate accounted for 17.13. As to improve sensory properties and select the best reception, three new marmalades with differing fruit share and sweeteners were produced in the second stage. Marmalades were also assessed sensory. The best mark was recorded with marmalade produced in compliance to reception 4 (40% of fruits and 30% of fructose). The chemical content was analyzed for this marmalade, and the energetic value determined (558.92 kJ/100 g). The colors of the raw material and finished products were compared instrumentally, i.e. via assessing surface color with three stimuli photoelectrical color-meter. Microbiological value, along with the content of heavy metals in the best estimated marmalade satisfied the requirements of the existing legal rules., Ponuda proizvoda namenjenih specijalnoj grupi potrošača - dijabetičarima je veoma oskudna. Asortiman proizvoda je mali, a cene relativno visoke za većinu potrošača. Iz ovih razloga nametnula se potreba za proizvodnjom dijabetičarskih želiranih proizvoda. Proizvedena je dijabetičarska marmelada od maline u laboratorijskim uslovima. U sirovini su određeni pH suva materija i frakcije pektinskih materija. Na osnovu senzorne ocene od više receptura odabrana je najpovoljnija. U gotovom proizvodu urađena je mikrobiološka analiza,hemijski sastav (pH, suva materija, šećeri, vitamin C mineralne materije, teški metali), površinska boja i energetska vrednost. Rezultati pokazuju da je dobijen proizvod vrhunskog kvaliteta.",
publisher = "Naučno voćarsko društvo Srbije, Čačak",
journal = "Jugoslovensko voćarstvo",
title = "Raspberry marmalade for diabetics, Marmelada od maline za dijabetičare",
volume = "38",
number = "147-148",
pages = "221-228",
url = "https://hdl.handle.net/21.15107/rcub_farfar_561"
}

Tepić, A. N., Vujičić, B. L., Cerović, A.,& Đorđević, B.. (2004). Raspberry marmalade for diabetics. in Jugoslovensko voćarstvo
Naučno voćarsko društvo Srbije, Čačak., 38(147-148), 221-228.
https://hdl.handle.net/21.15107/rcub_farfar_561

Tepić AN, Vujičić BL, Cerović A, Đorđević B. Raspberry marmalade for diabetics. in Jugoslovensko voćarstvo. 2004;38(147-148):221-228.
https://hdl.handle.net/21.15107/rcub_farfar_561 .

Tepić, Aleksandra N., Vujičić, Biserka L., Cerović, Aleksandra, Đorđević, Brižita, "Raspberry marmalade for diabetics" in Jugoslovensko voćarstvo, 38, no. 147-148 (2004):221-228,
https://hdl.handle.net/21.15107/rcub_farfar_561 .

TY  - CONF
AU  - Miletić, Ivanka
AU  - Topalov, R.
AU  - Šobajić, Slađana
AU  - Đorđević, Brižita
AU  - Cerović, Aleksandra
PY  - 2002
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/404
PB  - Savez farmaceutskih udruženja Srbije, Beograd
C3  - Arhiv za farmaciju
T1  - Insoluble and soluble dietary fibers in children’s nutrition
T1  - Nerastvorljiva i rastvorljiva dijetna vlakna u dečjoj ishrani
VL  - 52
IS  - 4
SP  - 756
EP  - 757
UR  - https://hdl.handle.net/21.15107/rcub_farfar_404
ER  - 

@conference{
author = "Miletić, Ivanka and Topalov, R. and Šobajić, Slađana and Đorđević, Brižita and Cerović, Aleksandra",
year = "2002",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Insoluble and soluble dietary fibers in children’s nutrition, Nerastvorljiva i rastvorljiva dijetna vlakna u dečjoj ishrani",
volume = "52",
number = "4",
pages = "756-757",
url = "https://hdl.handle.net/21.15107/rcub_farfar_404"
}

Miletić, I., Topalov, R., Šobajić, S., Đorđević, B.,& Cerović, A.. (2002). Insoluble and soluble dietary fibers in children’s nutrition. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 52(4), 756-757.
https://hdl.handle.net/21.15107/rcub_farfar_404

Miletić I, Topalov R, Šobajić S, Đorđević B, Cerović A. Insoluble and soluble dietary fibers in children’s nutrition. in Arhiv za farmaciju. 2002;52(4):756-757.
https://hdl.handle.net/21.15107/rcub_farfar_404 .

Miletić, Ivanka, Topalov, R., Šobajić, Slađana, Đorđević, Brižita, Cerović, Aleksandra, "Insoluble and soluble dietary fibers in children’s nutrition" in Arhiv za farmaciju, 52, no. 4 (2002):756-757,
https://hdl.handle.net/21.15107/rcub_farfar_404 .