TY  - JOUR
AU  - Škobić, Slađana
AU  - Marčetić, Mirjana
AU  - Kundaković-Vasović, Tatjana
AU  - Crnobarac, Jovan
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3465
AB  - Sweet flag rhizome (Acorus calamus L., Araceae) exhibits various biological activities such as sedative, anticonvulsant,
immunosuppressant, antidiabetic, and anti-inflammatory. This plant is protected in Serbia, but due to
its high market requirements, the cultivation of this species could be the final solution. The content and composition
of essential oils from 24 cultivated samples and five samples of sweet flag from natural populations, as
well as the influence of nitrogen fertilization on the composition of essential oils were studied. Essential oils were
analysed using GC and GC/MS. Statistical analysis included the ANOVA and PCA analysis. The total content of
essential oil was not significantly different between the natural (0.80–1.10%) and cultivated samples
(1.15–1.30%). In all essential oils main compounds were β-asarone (4.82–17.98%), cadinadienol
(10.14–13.95%), camphor (3.55–13.20%), and acorenone (9.68–12.64%). The cultivation of sweet flag showed
significant (p < 0.05) impact on the composition of essential oil and the content of β-asarone (4.82–17.07%,
mean 11.95±4.76 vs. 17.51–17.98%, mean 17.71 ± 2.23). The PCA analysis also separated the essential oils
from natural and cultivated conditions based on the content of β-asarone. On the other hand, the amount of the
fertilizer did not show any effect (p > 0.05) on the composition of investigated samples. The process of cultivation
increased the level of active, but potentially genotoxic and carcinogenic compound β-asarone. It would be
significant to determine the content of β-asarone routinely in the sweet flag rhizome, especially in the cultivated
plants.
PB  - Elsevier
T2  - Industrial Crops & Products
T1  - Nitrogen fertilization and the essential oils profile of the rhizomes of different sweet flag populations (Acorus calamus L.)
VL  - 142
SP  - 1
EP  - 5
DO  - 10.1016/j.indcrop.2019.111871
ER  - 

@article{
author = "Škobić, Slađana and Marčetić, Mirjana and Kundaković-Vasović, Tatjana and Crnobarac, Jovan",
year = "2019",
abstract = "Sweet flag rhizome (Acorus calamus L., Araceae) exhibits various biological activities such as sedative, anticonvulsant,
immunosuppressant, antidiabetic, and anti-inflammatory. This plant is protected in Serbia, but due to
its high market requirements, the cultivation of this species could be the final solution. The content and composition
of essential oils from 24 cultivated samples and five samples of sweet flag from natural populations, as
well as the influence of nitrogen fertilization on the composition of essential oils were studied. Essential oils were
analysed using GC and GC/MS. Statistical analysis included the ANOVA and PCA analysis. The total content of
essential oil was not significantly different between the natural (0.80–1.10%) and cultivated samples
(1.15–1.30%). In all essential oils main compounds were β-asarone (4.82–17.98%), cadinadienol
(10.14–13.95%), camphor (3.55–13.20%), and acorenone (9.68–12.64%). The cultivation of sweet flag showed
significant (p < 0.05) impact on the composition of essential oil and the content of β-asarone (4.82–17.07%,
mean 11.95±4.76 vs. 17.51–17.98%, mean 17.71 ± 2.23). The PCA analysis also separated the essential oils
from natural and cultivated conditions based on the content of β-asarone. On the other hand, the amount of the
fertilizer did not show any effect (p > 0.05) on the composition of investigated samples. The process of cultivation
increased the level of active, but potentially genotoxic and carcinogenic compound β-asarone. It would be
significant to determine the content of β-asarone routinely in the sweet flag rhizome, especially in the cultivated
plants.",
publisher = "Elsevier",
journal = "Industrial Crops & Products",
title = "Nitrogen fertilization and the essential oils profile of the rhizomes of different sweet flag populations (Acorus calamus L.)",
volume = "142",
pages = "1-5",
doi = "10.1016/j.indcrop.2019.111871"
}

Škobić, S., Marčetić, M., Kundaković-Vasović, T.,& Crnobarac, J.. (2019). Nitrogen fertilization and the essential oils profile of the rhizomes of different sweet flag populations (Acorus calamus L.). in Industrial Crops & Products
Elsevier., 142, 1-5.
https://doi.org/10.1016/j.indcrop.2019.111871

Škobić S, Marčetić M, Kundaković-Vasović T, Crnobarac J. Nitrogen fertilization and the essential oils profile of the rhizomes of different sweet flag populations (Acorus calamus L.). in Industrial Crops & Products. 2019;142:1-5.
doi:10.1016/j.indcrop.2019.111871 .

Škobić, Slađana, Marčetić, Mirjana, Kundaković-Vasović, Tatjana, Crnobarac, Jovan, "Nitrogen fertilization and the essential oils profile of the rhizomes of different sweet flag populations (Acorus calamus L.)" in Industrial Crops & Products, 142 (2019):1-5,
https://doi.org/10.1016/j.indcrop.2019.111871 . .

TY  - CONF
AU  - Marčetić, Mirjana
AU  - Škobić, Slađana
AU  - Radović, Jelena
AU  - Bošković, Nikola
AU  - Damjanović, Anđela
AU  - Kundaković, Tatjana
AU  - Crnobarac, Jovan
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5272
AB  - Sweet flag rhizome (Acorus calamus L., Acoraceae) possesses various biological activities such as sedative, anticonvulsant, immunosuppressant, antidiabetic, antiinflammatory etc. [1]. The aim was to study the content and composition of essential oils from 24 rhizome samples of the cultivated sweet flag, their comparison with the samples from 5 natural habitats, and the influence of nitrogen fertilization on the composition of essential oils. Essential oils were analyzed using GC and GC/MS. Statistical analysis included the analysis of variance and cluster analysis. The content of essential oil was not significantly different between the samples from natural habitats (0.8-1.1%) and cultures (0.3-2.2%). All samples contained dominant oxygenated sesquiterpenes (24.5-32.6%), phenylpropanoids (5.7-22.5%), and oxygenated monoterpenes (4.4-19.2%). The main components were β-asarone (10.4-21.4%), camphor (3.5-15.2%), acorenone (9.3-14.1%) and cyperotudone (7.3-11.0%). The contents of β-asarone and aristolone were significantly higher (p<0.05) in cultivated plants. The nitrogen fertilization during the cultivation did not have a significant influence (p<0.05) on the content and composition of the essential oils.
PB  - University of Niš, Serbia
C3  - Facta Universitatis, Series: Physics, Chemistry and Technology: 49th International Symposium on Essential Oils (ISEO2018), Book of Abstracts
T1  - The composition of the essential oils of Acorus calamus L. rhizomes from different habitats
VL  - 16
IS  - 1 Special issue
SP  - 105
EP  - 105
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5272
ER  - 

@conference{
author = "Marčetić, Mirjana and Škobić, Slađana and Radović, Jelena and Bošković, Nikola and Damjanović, Anđela and Kundaković, Tatjana and Crnobarac, Jovan",
year = "2018",
abstract = "Sweet flag rhizome (Acorus calamus L., Acoraceae) possesses various biological activities such as sedative, anticonvulsant, immunosuppressant, antidiabetic, antiinflammatory etc. [1]. The aim was to study the content and composition of essential oils from 24 rhizome samples of the cultivated sweet flag, their comparison with the samples from 5 natural habitats, and the influence of nitrogen fertilization on the composition of essential oils. Essential oils were analyzed using GC and GC/MS. Statistical analysis included the analysis of variance and cluster analysis. The content of essential oil was not significantly different between the samples from natural habitats (0.8-1.1%) and cultures (0.3-2.2%). All samples contained dominant oxygenated sesquiterpenes (24.5-32.6%), phenylpropanoids (5.7-22.5%), and oxygenated monoterpenes (4.4-19.2%). The main components were β-asarone (10.4-21.4%), camphor (3.5-15.2%), acorenone (9.3-14.1%) and cyperotudone (7.3-11.0%). The contents of β-asarone and aristolone were significantly higher (p<0.05) in cultivated plants. The nitrogen fertilization during the cultivation did not have a significant influence (p<0.05) on the content and composition of the essential oils.",
publisher = "University of Niš, Serbia",
journal = "Facta Universitatis, Series: Physics, Chemistry and Technology: 49th International Symposium on Essential Oils (ISEO2018), Book of Abstracts",
title = "The composition of the essential oils of Acorus calamus L. rhizomes from different habitats",
volume = "16",
number = "1 Special issue",
pages = "105-105",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5272"
}

Marčetić, M., Škobić, S., Radović, J., Bošković, N., Damjanović, A., Kundaković, T.,& Crnobarac, J.. (2018). The composition of the essential oils of Acorus calamus L. rhizomes from different habitats. in Facta Universitatis, Series: Physics, Chemistry and Technology: 49th International Symposium on Essential Oils (ISEO2018), Book of Abstracts
University of Niš, Serbia., 16(1 Special issue), 105-105.
https://hdl.handle.net/21.15107/rcub_farfar_5272

Marčetić M, Škobić S, Radović J, Bošković N, Damjanović A, Kundaković T, Crnobarac J. The composition of the essential oils of Acorus calamus L. rhizomes from different habitats. in Facta Universitatis, Series: Physics, Chemistry and Technology: 49th International Symposium on Essential Oils (ISEO2018), Book of Abstracts. 2018;16(1 Special issue):105-105.
https://hdl.handle.net/21.15107/rcub_farfar_5272 .

Marčetić, Mirjana, Škobić, Slađana, Radović, Jelena, Bošković, Nikola, Damjanović, Anđela, Kundaković, Tatjana, Crnobarac, Jovan, "The composition of the essential oils of Acorus calamus L. rhizomes from different habitats" in Facta Universitatis, Series: Physics, Chemistry and Technology: 49th International Symposium on Essential Oils (ISEO2018), Book of Abstracts, 16, no. 1 Special issue (2018):105-105,
https://hdl.handle.net/21.15107/rcub_farfar_5272 .