TY  - JOUR
AU  - Mijatović, Stefan
AU  - Antić-Stanković, Jelena
AU  - Čolović Čalovski, Ivana, Ivana
AU  - Dubljanin, Eleonora
AU  - Pljevljakušić, Dejan
AU  - Bigović, Dubravka
AU  - Džamić, Aleksandar
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4292
AB  - The aim of our study was to determine the susceptibility of 15 Candida albicans sputum isolates on fluconazole and caspofungin, as well as the antifungal potential of Lavandula angustifolia essential oil (LAEO). The commercial LAEO was analyzed using gas chromatography-mass spectrometry. The antifungal activity was evaluated using EUCAST protocol. A killing assay was performed to evaluate kinetics of 2% LAEO within 30 min treatment. LAEO with major constituents’ linalool (33.4%) and linalyl acetate (30.5%) effective inhibited grows of C. albicans in concentration range 0.5–2%. Fluconazole activity was noted in 67% of the isolates with MICs in range 0.06–1 µg/mL. Surprisingly, 40% of isolates were non-wild-type (non-WT), while MICs for WT ranged between 0.125–0.25 µg/mL. There were no significant differences in the LAEO MICs among fluconazole-resistant and fluconazole-susceptible sputum strains (p = 0.31) and neither among caspofungin non-WT and WT isolates (p = 0.79). The 2% LAEO rapidly achieved 50% growth reduction in all tested strains between 0.2 and 3.5 min. Within 30 min, the same LAEO concentration exhibited a 99.9% reduction in 27% isolates. This study demonstrated that 2% solution of LAEO showed a significant antifungal activity which is equally effective against fluconazole and caspofungin susceptible and less-susceptible strains.
PB  - MDPI
T2  - Molecules
T1  - Antifungal Activity of Lavandula angustifolia Essential Oil against Candida albicans: Time-Kill Study on Pediatric Sputum Isolates
VL  - 27
IS  - 19
DO  - 10.3390/molecules27196300
ER  - 

@article{
author = "Mijatović, Stefan and Antić-Stanković, Jelena and Čolović Čalovski, Ivana, Ivana and Dubljanin, Eleonora and Pljevljakušić, Dejan and Bigović, Dubravka and Džamić, Aleksandar",
year = "2022",
abstract = "The aim of our study was to determine the susceptibility of 15 Candida albicans sputum isolates on fluconazole and caspofungin, as well as the antifungal potential of Lavandula angustifolia essential oil (LAEO). The commercial LAEO was analyzed using gas chromatography-mass spectrometry. The antifungal activity was evaluated using EUCAST protocol. A killing assay was performed to evaluate kinetics of 2% LAEO within 30 min treatment. LAEO with major constituents’ linalool (33.4%) and linalyl acetate (30.5%) effective inhibited grows of C. albicans in concentration range 0.5–2%. Fluconazole activity was noted in 67% of the isolates with MICs in range 0.06–1 µg/mL. Surprisingly, 40% of isolates were non-wild-type (non-WT), while MICs for WT ranged between 0.125–0.25 µg/mL. There were no significant differences in the LAEO MICs among fluconazole-resistant and fluconazole-susceptible sputum strains (p = 0.31) and neither among caspofungin non-WT and WT isolates (p = 0.79). The 2% LAEO rapidly achieved 50% growth reduction in all tested strains between 0.2 and 3.5 min. Within 30 min, the same LAEO concentration exhibited a 99.9% reduction in 27% isolates. This study demonstrated that 2% solution of LAEO showed a significant antifungal activity which is equally effective against fluconazole and caspofungin susceptible and less-susceptible strains.",
publisher = "MDPI",
journal = "Molecules",
title = "Antifungal Activity of Lavandula angustifolia Essential Oil against Candida albicans: Time-Kill Study on Pediatric Sputum Isolates",
volume = "27",
number = "19",
doi = "10.3390/molecules27196300"
}

Mijatović, S., Antić-Stanković, J., Čolović Čalovski, I. I., Dubljanin, E., Pljevljakušić, D., Bigović, D.,& Džamić, A.. (2022). Antifungal Activity of Lavandula angustifolia Essential Oil against Candida albicans: Time-Kill Study on Pediatric Sputum Isolates. in Molecules
MDPI., 27(19).
https://doi.org/10.3390/molecules27196300

Mijatović S, Antić-Stanković J, Čolović Čalovski II, Dubljanin E, Pljevljakušić D, Bigović D, Džamić A. Antifungal Activity of Lavandula angustifolia Essential Oil against Candida albicans: Time-Kill Study on Pediatric Sputum Isolates. in Molecules. 2022;27(19).
doi:10.3390/molecules27196300 .

Mijatović, Stefan, Antić-Stanković, Jelena, Čolović Čalovski, Ivana, Ivana, Dubljanin, Eleonora, Pljevljakušić, Dejan, Bigović, Dubravka, Džamić, Aleksandar, "Antifungal Activity of Lavandula angustifolia Essential Oil against Candida albicans: Time-Kill Study on Pediatric Sputum Isolates" in Molecules, 27, no. 19 (2022),
https://doi.org/10.3390/molecules27196300 . .

TY  - CONF
AU  - Tadić, Ivana
AU  - Tasić, Ljiljana
AU  - Bošković, Isidora
AU  - Mijatović, Stefan
AU  - Jović, Sanja
AU  - Odalović, Marina
AU  - Lakić, Dragana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4236
AB  - Pacijenti starije životne dobi primenjuju uglavnom veliki broj lekova. Tokom procesa izdavanja lekova i savetovanja pacijenata farmaceuti mogu značajno da doprinesu racionalnoj upotrebi lekova. Cilj ovog istraživanja bio je da se ispitaju stavovi farmaceuta o uslugama savetovanja starijih pacijenata o primeni lekova. Istraživanje je sprovedeno tokom 2018. godine u više lanaca apoteka u Srbiji uz pomoć namenski kreiranog on‐line upitnika. Upitnike su popunjavali samo farmaceuti. U istraživanju je učestvovalo 154 farmaceuta, pretežno ženskog pola (87,1%), prosečne starosti 38,3 godina i radnog staža 12,8 godina. Kada su u pitanju informacije o lekovima, pacijenti najviše veruju lekarima specijalistima (39,6%), farmaceutima (31,2%), lekarima opšte prakse (18,8%), i ljudima iz njihovog okruženja (10,4%). Farmaceuti najčešće pružaju informacije o upotrebi lekova (100,0%), indikacijama za upotrebu lekova (91,6%), dužini primene leka (77,9%), interakcijama sa hranom i lekovima (72,7%) i neželjenim reakcijama na lek (53,2%). Gužva u apoteci je najčešća (73,6%) barijera za adekvatno savetovanje pacijenata prepoznata od strane farmaceuta. Oko polovine farmaceuta (51,6%) smatra da usluga savetovanja starijih pacijenata treba da bude plaćena. Farmaceuti imaju jasan stav da je usluga savetovanja starijih pacijenata o primeni lekova od velikog značaja za kvalitet zdravstvene zaštite. Ovakva vrsta analize može pružiti smernice kako da se razviju farmaceutske usluge i kako da se implementiraju u svakodnevnoj praksi.
AB  - Elderly patients mostly use a large number of medicines. Pharmacists can contribute significantly to the rational use of medicines during the process of dispensing medicines and patient counseling. The aim of this study was to examine the attitudes of pharmacists about the services of counseling elderly patients on the safe use of medicines. The study was conducted in 2018 within several pharmacy chains in Serbia using on‐line questionnaire designed for this research. The questionnaires were filled out only by pharmacists. The study included 154 pharmacists, mostly female (87.1%), aged 38.3 years and 12.8 years of service in average. When it comes to information on medicines, patients mostly trust physicians (39.6%), pharmacists (31.2%), general practitioners (18.8%) and friends (10.4%). Pharmacists often provide information on medicines use
(100.0%), indications (91.6%), duration of administration (77.9%), medicines interactions with food and other medicines (72.7%) and adverse drug reactions (53.2%). The most common barrier for adequate counseling of patients recognized by pharmacist was crowded pharmacy (73.6%). About half of pharmacists (51.6%) think that elderly patient counseling services should be paid. Pharmacists think that the counseling service of elderly patients about safe use of medicines is of great importance for the quality of health care. This type of analysis can provide guidance on how to develop and implement pharmaceutical services.
PB  - Beograd : Savez fakmaceutskih udruženja Srbije
C3  - Arhiv za farmaciju
T1  - Pružanje usluge savetovanja starijih pacijenata o primeni Lekova – stavovi farmaceuta
T1  - Provision of pharmaceutical service to elderly patients about safe use of medicines ‐ the attitudes of pharmacists
VL  - 68
IS  - 3
SP  - 749
EP  - 750
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4236
ER  - 

@conference{
author = "Tadić, Ivana and Tasić, Ljiljana and Bošković, Isidora and Mijatović, Stefan and Jović, Sanja and Odalović, Marina and Lakić, Dragana",
year = "2018",
abstract = "Pacijenti starije životne dobi primenjuju uglavnom veliki broj lekova. Tokom procesa izdavanja lekova i savetovanja pacijenata farmaceuti mogu značajno da doprinesu racionalnoj upotrebi lekova. Cilj ovog istraživanja bio je da se ispitaju stavovi farmaceuta o uslugama savetovanja starijih pacijenata o primeni lekova. Istraživanje je sprovedeno tokom 2018. godine u više lanaca apoteka u Srbiji uz pomoć namenski kreiranog on‐line upitnika. Upitnike su popunjavali samo farmaceuti. U istraživanju je učestvovalo 154 farmaceuta, pretežno ženskog pola (87,1%), prosečne starosti 38,3 godina i radnog staža 12,8 godina. Kada su u pitanju informacije o lekovima, pacijenti najviše veruju lekarima specijalistima (39,6%), farmaceutima (31,2%), lekarima opšte prakse (18,8%), i ljudima iz njihovog okruženja (10,4%). Farmaceuti najčešće pružaju informacije o upotrebi lekova (100,0%), indikacijama za upotrebu lekova (91,6%), dužini primene leka (77,9%), interakcijama sa hranom i lekovima (72,7%) i neželjenim reakcijama na lek (53,2%). Gužva u apoteci je najčešća (73,6%) barijera za adekvatno savetovanje pacijenata prepoznata od strane farmaceuta. Oko polovine farmaceuta (51,6%) smatra da usluga savetovanja starijih pacijenata treba da bude plaćena. Farmaceuti imaju jasan stav da je usluga savetovanja starijih pacijenata o primeni lekova od velikog značaja za kvalitet zdravstvene zaštite. Ovakva vrsta analize može pružiti smernice kako da se razviju farmaceutske usluge i kako da se implementiraju u svakodnevnoj praksi., Elderly patients mostly use a large number of medicines. Pharmacists can contribute significantly to the rational use of medicines during the process of dispensing medicines and patient counseling. The aim of this study was to examine the attitudes of pharmacists about the services of counseling elderly patients on the safe use of medicines. The study was conducted in 2018 within several pharmacy chains in Serbia using on‐line questionnaire designed for this research. The questionnaires were filled out only by pharmacists. The study included 154 pharmacists, mostly female (87.1%), aged 38.3 years and 12.8 years of service in average. When it comes to information on medicines, patients mostly trust physicians (39.6%), pharmacists (31.2%), general practitioners (18.8%) and friends (10.4%). Pharmacists often provide information on medicines use
(100.0%), indications (91.6%), duration of administration (77.9%), medicines interactions with food and other medicines (72.7%) and adverse drug reactions (53.2%). The most common barrier for adequate counseling of patients recognized by pharmacist was crowded pharmacy (73.6%). About half of pharmacists (51.6%) think that elderly patient counseling services should be paid. Pharmacists think that the counseling service of elderly patients about safe use of medicines is of great importance for the quality of health care. This type of analysis can provide guidance on how to develop and implement pharmaceutical services.",
publisher = "Beograd : Savez fakmaceutskih udruženja Srbije",
journal = "Arhiv za farmaciju",
title = "Pružanje usluge savetovanja starijih pacijenata o primeni Lekova – stavovi farmaceuta, Provision of pharmaceutical service to elderly patients about safe use of medicines ‐ the attitudes of pharmacists",
volume = "68",
number = "3",
pages = "749-750",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4236"
}

Tadić, I., Tasić, L., Bošković, I., Mijatović, S., Jović, S., Odalović, M.,& Lakić, D.. (2018). Pružanje usluge savetovanja starijih pacijenata o primeni Lekova – stavovi farmaceuta. in Arhiv za farmaciju
Beograd : Savez fakmaceutskih udruženja Srbije., 68(3), 749-750.
https://hdl.handle.net/21.15107/rcub_farfar_4236

Tadić I, Tasić L, Bošković I, Mijatović S, Jović S, Odalović M, Lakić D. Pružanje usluge savetovanja starijih pacijenata o primeni Lekova – stavovi farmaceuta. in Arhiv za farmaciju. 2018;68(3):749-750.
https://hdl.handle.net/21.15107/rcub_farfar_4236 .

Tadić, Ivana, Tasić, Ljiljana, Bošković, Isidora, Mijatović, Stefan, Jović, Sanja, Odalović, Marina, Lakić, Dragana, "Pružanje usluge savetovanja starijih pacijenata o primeni Lekova – stavovi farmaceuta" in Arhiv za farmaciju, 68, no. 3 (2018):749-750,
https://hdl.handle.net/21.15107/rcub_farfar_4236 .