TY  - JOUR
AU  - Đogo, Svetlana
AU  - Ražić, Slavica
AU  - Manojlović, Dragan
AU  - Slavković, Latinka
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1610
AB  - Mentha piperita L. (Lamiaceae) was cultivated under the controlled laboratory conditions in the presence of varying levels of trivalent and hexavalent chromium in order to determine its capacity to control chromium uptake and its tolerance limit. The plants were grown in pots at 25°C with controlled soil moisture (about 80 % of the water retention capacity). The soil was treated with increasing concentrations of Cr(NO3)3 (40, 80, 120, and 200 mg kg-1) and K2Cr2O7 (2.5, 5, 10, and 15 mg kg-1). A control group of plants was grown without the addition of chromium to the soil. For each concentration, three acidity levels were tested: natural, one pH unit below and one above the natural acidity of the soil (pH2 6, pH1 5 and pH3 7). The plant samples were digested according to the standard procedure and chromium content was determined by GFAAS. For all plants, the transportation index was calculated and the results (expressed in mg kg-1) at pH1, pH2 and pH3, respectively, were: 0.21-0.80, 0.06-1.06 and 0.04-0.52. The recoveries were good (72.73-115.3 %) as evidenced by the analysis of certified reference materials (NIST SRM 8433 - Corn Bran and NIST SRM 1547 - Peach Leaves). The mobility of chromium through the plants tissues is discussed in regard to its competition with iron and manganese for transport binding sites; hence Mn and Fe were also determined.
AB  - Cilj ovog rada je bio analiza limita tolerancije za usvajanje Cr(III) i Cr(VI) iz zagađenog zemljišta i određivanje kapaciteta medicinske biljke Mentha piperita (L. Lamiaceae) radi kontrole unosa ovog metala. Biljke su uzgajane u plastičnim posudama, pri sobnoj temperaturi od 25 °C i održavanoj vlažnosti zemljišta na oko 80% retencionog vodenog kapaciteta. Zemljište na kome su biljke uzgajane kontaminirano je rastvorom Cr(III)-nitrata (40, 80, 120, i 200 mg kg-1) i K2Cr2O7 (2,5; 5; 10; i 15 mg kg-1). Kontrolna grupa biljaka je rasla pod istim uslovima bez dodavanja hroma. Za svaku koncentraciju hroma u zemljištu pripremane su serije uzoraka na tri nivoa kiselosti: prirodni i za po jednu jedinicu kiseliji i bazniji (pH2 6, pH1 5 and pH3 7). Uzorci biljaka su pripremani za analizu prema standardnoj proceduri i hrom je određivan metodom atomske apsorpcione spektrometrije sa grafitnom kivetom, GFAAS. Za uzorke na sva tri nivoa kiselosti izračunat je transportacioni indeks i dobijene vrednosti su u sledećim intervalima: 0,21-0,80; 0,06-1,06; 0,04-0,52. Tačnost metode (72,73-115,3 %) je potvrđena analizom hroma u uzorcima standardnih referentnih materijala (NIST SRM 8433 - Corn Bran and NIST SRM 1547 - Peach Leaves). Mobilnost hroma iz korenovog sistema u nadzemni deo biljke je diskutovana i sa aspekta kompeticije sa gvožđem i manganom za ista transportna mesta, pa su u tom smislu u uzorcima određene i koncentracije ovih metala.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry
T1  - Analiza biodostupnosti Cr(III) i Cr(VI) zasnovana na određivanju hroma u biljci Mentha piperita metodom atomske apsorpcione spektrometrije sa grafitnom kivetom
VL  - 76
IS  - 1
SP  - 143
EP  - 153
DO  - 10.2298/JSC100401130D
ER  - 

@article{
author = "Đogo, Svetlana and Ražić, Slavica and Manojlović, Dragan and Slavković, Latinka",
year = "2011",
abstract = "Mentha piperita L. (Lamiaceae) was cultivated under the controlled laboratory conditions in the presence of varying levels of trivalent and hexavalent chromium in order to determine its capacity to control chromium uptake and its tolerance limit. The plants were grown in pots at 25°C with controlled soil moisture (about 80 % of the water retention capacity). The soil was treated with increasing concentrations of Cr(NO3)3 (40, 80, 120, and 200 mg kg-1) and K2Cr2O7 (2.5, 5, 10, and 15 mg kg-1). A control group of plants was grown without the addition of chromium to the soil. For each concentration, three acidity levels were tested: natural, one pH unit below and one above the natural acidity of the soil (pH2 6, pH1 5 and pH3 7). The plant samples were digested according to the standard procedure and chromium content was determined by GFAAS. For all plants, the transportation index was calculated and the results (expressed in mg kg-1) at pH1, pH2 and pH3, respectively, were: 0.21-0.80, 0.06-1.06 and 0.04-0.52. The recoveries were good (72.73-115.3 %) as evidenced by the analysis of certified reference materials (NIST SRM 8433 - Corn Bran and NIST SRM 1547 - Peach Leaves). The mobility of chromium through the plants tissues is discussed in regard to its competition with iron and manganese for transport binding sites; hence Mn and Fe were also determined., Cilj ovog rada je bio analiza limita tolerancije za usvajanje Cr(III) i Cr(VI) iz zagađenog zemljišta i određivanje kapaciteta medicinske biljke Mentha piperita (L. Lamiaceae) radi kontrole unosa ovog metala. Biljke su uzgajane u plastičnim posudama, pri sobnoj temperaturi od 25 °C i održavanoj vlažnosti zemljišta na oko 80% retencionog vodenog kapaciteta. Zemljište na kome su biljke uzgajane kontaminirano je rastvorom Cr(III)-nitrata (40, 80, 120, i 200 mg kg-1) i K2Cr2O7 (2,5; 5; 10; i 15 mg kg-1). Kontrolna grupa biljaka je rasla pod istim uslovima bez dodavanja hroma. Za svaku koncentraciju hroma u zemljištu pripremane su serije uzoraka na tri nivoa kiselosti: prirodni i za po jednu jedinicu kiseliji i bazniji (pH2 6, pH1 5 and pH3 7). Uzorci biljaka su pripremani za analizu prema standardnoj proceduri i hrom je određivan metodom atomske apsorpcione spektrometrije sa grafitnom kivetom, GFAAS. Za uzorke na sva tri nivoa kiselosti izračunat je transportacioni indeks i dobijene vrednosti su u sledećim intervalima: 0,21-0,80; 0,06-1,06; 0,04-0,52. Tačnost metode (72,73-115,3 %) je potvrđena analizom hroma u uzorcima standardnih referentnih materijala (NIST SRM 8433 - Corn Bran and NIST SRM 1547 - Peach Leaves). Mobilnost hroma iz korenovog sistema u nadzemni deo biljke je diskutovana i sa aspekta kompeticije sa gvožđem i manganom za ista transportna mesta, pa su u tom smislu u uzorcima određene i koncentracije ovih metala.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry, Analiza biodostupnosti Cr(III) i Cr(VI) zasnovana na određivanju hroma u biljci Mentha piperita metodom atomske apsorpcione spektrometrije sa grafitnom kivetom",
volume = "76",
number = "1",
pages = "143-153",
doi = "10.2298/JSC100401130D"
}

Đogo, S., Ražić, S., Manojlović, D.,& Slavković, L.. (2011). Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 76(1), 143-153.
https://doi.org/10.2298/JSC100401130D

Đogo S, Ražić S, Manojlović D, Slavković L. Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry. in Journal of the Serbian Chemical Society. 2011;76(1):143-153.
doi:10.2298/JSC100401130D .

Đogo, Svetlana, Ražić, Slavica, Manojlović, Dragan, Slavković, Latinka, "Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry" in Journal of the Serbian Chemical Society, 76, no. 1 (2011):143-153,
https://doi.org/10.2298/JSC100401130D . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Đogo-Mračević, Svetlana
AU  - Slavković, Latinka
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1056
AB  - Trace and major elements were determined in medicinal herbs (Cynara scolymus, Matricaria chamomilla, Artemisia absinthium L., Achillea millefolium, and Inula britannica) as well as in rhizosphere soil samples. Based on the results obtained after microwave-acid-assisted digestion (nitric acid + hydrogen peroxide) and single-step extraction (ammonium acetate), the real and potential acidity and redox potential of the soils, uptake, mobility, and bioavailability of potassium, calcium, magnesium, iron, manganese, copper, zinc, nickel, chromium, lead, and cadmium are discussed. By calculating the bioconcentration factors and their deviation from the recommended values, elevated concentrations, were explained in terms of contamination and pollution. The concentrations measured in both plants and soil samples were below maximum allowable concentration ranges considered for the European Union.
PB  - Springer Japan Kk, Tokyo
T2  - Journal of Natural Medicines
T1  - Investigation on bioavailability of some essential and toxic elements in medicinal herbs
VL  - 62
IS  - 3
SP  - 340
EP  - 344
DO  - 10.1007/s11418-008-0240-5
ER  - 

@article{
author = "Ražić, Slavica and Đogo-Mračević, Svetlana and Slavković, Latinka",
year = "2008",
abstract = "Trace and major elements were determined in medicinal herbs (Cynara scolymus, Matricaria chamomilla, Artemisia absinthium L., Achillea millefolium, and Inula britannica) as well as in rhizosphere soil samples. Based on the results obtained after microwave-acid-assisted digestion (nitric acid + hydrogen peroxide) and single-step extraction (ammonium acetate), the real and potential acidity and redox potential of the soils, uptake, mobility, and bioavailability of potassium, calcium, magnesium, iron, manganese, copper, zinc, nickel, chromium, lead, and cadmium are discussed. By calculating the bioconcentration factors and their deviation from the recommended values, elevated concentrations, were explained in terms of contamination and pollution. The concentrations measured in both plants and soil samples were below maximum allowable concentration ranges considered for the European Union.",
publisher = "Springer Japan Kk, Tokyo",
journal = "Journal of Natural Medicines",
title = "Investigation on bioavailability of some essential and toxic elements in medicinal herbs",
volume = "62",
number = "3",
pages = "340-344",
doi = "10.1007/s11418-008-0240-5"
}

Ražić, S., Đogo-Mračević, S.,& Slavković, L.. (2008). Investigation on bioavailability of some essential and toxic elements in medicinal herbs. in Journal of Natural Medicines
Springer Japan Kk, Tokyo., 62(3), 340-344.
https://doi.org/10.1007/s11418-008-0240-5

Ražić S, Đogo-Mračević S, Slavković L. Investigation on bioavailability of some essential and toxic elements in medicinal herbs. in Journal of Natural Medicines. 2008;62(3):340-344.
doi:10.1007/s11418-008-0240-5 .

Ražić, Slavica, Đogo-Mračević, Svetlana, Slavković, Latinka, "Investigation on bioavailability of some essential and toxic elements in medicinal herbs" in Journal of Natural Medicines, 62, no. 3 (2008):340-344,
https://doi.org/10.1007/s11418-008-0240-5 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Đogo, Svetlana
AU  - Slavković, Latinka
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/882
AB  - Eleven elements (Cu, Zn, Mn, Fe, K, Ca, Mg, Ni, Cd, Pb and Cr) in seven herbal drugs (Salviae folium, Menthae piperitae folium, Melissae folium, Lavandulae flos, Basilici herba, Marubii herba and Origani herba) and in rhizosphere soil samples were determined. A microwave digestion procedure preceded the measurements by the flame and electrothermal atomic absorption spectroscopy techniques (FAAS, ETAAS). For potentially hazardous elements and their bioavailability, BCF values were also calculated and discussed in order to identify possible sources of specific elements.
AB  - Određen je sadržaj 11 elemenata (Cu, Zn,Mn, Fe, K, Ca, Mg, Ni, Cd, Pb i Cr) u sedam biljnih droga Salviae folium, Menthae piperitae folium, Melissae folium, Lavandulae flos, Basilici herba, Marubiti herba i Origani herba) kao i u uzorcima zemljišta (rizosfere). Mikrotalasna digestija uzoraka je prethodila određivanju koncentracije elemenata primenom metoda plamene i elektrotermalne atomske apsorpcione spektroskopije. Izračunati su i biokoncentracioni faktori za potencijalno toksične elemente u cilju razmatranja potencijalne bioraspoloživosti, kao i identifikacije mogućih izvora zagađenja.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Inorganic analysis of herbal drugs. Part II: Plant and soil analysis: Diverse bioavailability and uptake of essential and toxic elements
T1  - Neorganska analiza biljnih droga. II deo - analiza biljaka i zemljišta - različita bioraspoloživost i unos esencijalnih i toksičnih elemenata
VL  - 71
IS  - 10
SP  - 1095
EP  - 1105
DO  - 10.2298/JSC0610095R
ER  - 

@article{
author = "Ražić, Slavica and Đogo, Svetlana and Slavković, Latinka",
year = "2006",
abstract = "Eleven elements (Cu, Zn, Mn, Fe, K, Ca, Mg, Ni, Cd, Pb and Cr) in seven herbal drugs (Salviae folium, Menthae piperitae folium, Melissae folium, Lavandulae flos, Basilici herba, Marubii herba and Origani herba) and in rhizosphere soil samples were determined. A microwave digestion procedure preceded the measurements by the flame and electrothermal atomic absorption spectroscopy techniques (FAAS, ETAAS). For potentially hazardous elements and their bioavailability, BCF values were also calculated and discussed in order to identify possible sources of specific elements., Određen je sadržaj 11 elemenata (Cu, Zn,Mn, Fe, K, Ca, Mg, Ni, Cd, Pb i Cr) u sedam biljnih droga Salviae folium, Menthae piperitae folium, Melissae folium, Lavandulae flos, Basilici herba, Marubiti herba i Origani herba) kao i u uzorcima zemljišta (rizosfere). Mikrotalasna digestija uzoraka je prethodila određivanju koncentracije elemenata primenom metoda plamene i elektrotermalne atomske apsorpcione spektroskopije. Izračunati su i biokoncentracioni faktori za potencijalno toksične elemente u cilju razmatranja potencijalne bioraspoloživosti, kao i identifikacije mogućih izvora zagađenja.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Inorganic analysis of herbal drugs. Part II: Plant and soil analysis: Diverse bioavailability and uptake of essential and toxic elements, Neorganska analiza biljnih droga. II deo - analiza biljaka i zemljišta - različita bioraspoloživost i unos esencijalnih i toksičnih elemenata",
volume = "71",
number = "10",
pages = "1095-1105",
doi = "10.2298/JSC0610095R"
}

Ražić, S., Đogo, S.,& Slavković, L.. (2006). Inorganic analysis of herbal drugs. Part II: Plant and soil analysis: Diverse bioavailability and uptake of essential and toxic elements. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 71(10), 1095-1105.
https://doi.org/10.2298/JSC0610095R

Ražić S, Đogo S, Slavković L. Inorganic analysis of herbal drugs. Part II: Plant and soil analysis: Diverse bioavailability and uptake of essential and toxic elements. in Journal of the Serbian Chemical Society. 2006;71(10):1095-1105.
doi:10.2298/JSC0610095R .

Ražić, Slavica, Đogo, Svetlana, Slavković, Latinka, "Inorganic analysis of herbal drugs. Part II: Plant and soil analysis: Diverse bioavailability and uptake of essential and toxic elements" in Journal of the Serbian Chemical Society, 71, no. 10 (2006):1095-1105,
https://doi.org/10.2298/JSC0610095R . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Đogo-Mračević, Svetlana
AU  - Slavković, Latinka
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/686
AB  - Seven herbal drugs and corresponding rhizosphere soil samples from the plantation near Belgrade were analyzed for mineral content. Eleven metals (Cu, Zn, Mn, Fe, Cr, Ni, Pb, Cd, Ca, K and Mg) were selected as chemical features/descriptors and analyzed by FAAS/FAES and ETAAS. In a chemometrics evaluation of investigated plants-soil system, univariate, as well as multivariate statistics methods were applied. Principal component analysis (PCA) allowed considerable reduction in a number of variables and the detection of structure in the relationships between metals that give complementary information about the relations and elemental patterns within plants-soil system. The power of chemometrics was also used in exploring the potential natural and/or anthropogenic sources responsible for metal content in both medicinal plants and soil samples. Hierarchical cluster analysis (HCA) was used to explore herbal drugs grouping according to corresponding soil samples as additional information to the output obtained by PCA.
PB  - Elsevier Science BV, Amsterdam
T2  - Microchemical Journal
T1  - Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content
VL  - 84
IS  - 1-2
SP  - 93
EP  - 101
DO  - 10.1016/j.microc.2006.05.008
ER  - 

@article{
author = "Ražić, Slavica and Đogo-Mračević, Svetlana and Slavković, Latinka",
year = "2006",
abstract = "Seven herbal drugs and corresponding rhizosphere soil samples from the plantation near Belgrade were analyzed for mineral content. Eleven metals (Cu, Zn, Mn, Fe, Cr, Ni, Pb, Cd, Ca, K and Mg) were selected as chemical features/descriptors and analyzed by FAAS/FAES and ETAAS. In a chemometrics evaluation of investigated plants-soil system, univariate, as well as multivariate statistics methods were applied. Principal component analysis (PCA) allowed considerable reduction in a number of variables and the detection of structure in the relationships between metals that give complementary information about the relations and elemental patterns within plants-soil system. The power of chemometrics was also used in exploring the potential natural and/or anthropogenic sources responsible for metal content in both medicinal plants and soil samples. Hierarchical cluster analysis (HCA) was used to explore herbal drugs grouping according to corresponding soil samples as additional information to the output obtained by PCA.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Microchemical Journal",
title = "Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content",
volume = "84",
number = "1-2",
pages = "93-101",
doi = "10.1016/j.microc.2006.05.008"
}

Ražić, S., Đogo-Mračević, S.,& Slavković, L.. (2006). Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content. in Microchemical Journal
Elsevier Science BV, Amsterdam., 84(1-2), 93-101.
https://doi.org/10.1016/j.microc.2006.05.008

Ražić S, Đogo-Mračević S, Slavković L. Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content. in Microchemical Journal. 2006;84(1-2):93-101.
doi:10.1016/j.microc.2006.05.008 .

Ražić, Slavica, Đogo-Mračević, Svetlana, Slavković, Latinka, "Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content" in Microchemical Journal, 84, no. 1-2 (2006):93-101,
https://doi.org/10.1016/j.microc.2006.05.008 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Đogo, Svetlana
AU  - Slavković, Latinka
AU  - Popović, Aleksandar
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/662
AB  - Elemental profiles of the total analyte content of major, minor and trace elements (Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and B) in 8 herbal drugs, originating from medicinal plants of the family Lamiacae, were determined. Flame atomic absorption/ emission spectroscopy (FAAS/FAES), inductively coupled plasma atomic emission spectroscopy (ICP-AES) and energy dispersive X-ray fluorescence (EDXRF) were applied, and the advantages and limitations of these techniques are also discussed. The whole procedure, from sample preparation via dissolution to the actual measurements, was validated by using CRM (NIST 1573a - Tomato leaves). The recovery values obtained were in the range 90.64 - 101.58 %. A high degree of similarity in their elemental profiles was noticed from the results of qualitative analysis, while quantitative analysis shows significant diversity due to the variety of the influencing sources. The medicinal plants investigated in this work contained Cu (5.92- 14.79 mg kg-1), Zn (15.0 - 43.0 mg kg-1), Mn (25 - 111 mg kg-1), Fe (74 - 546 mg kg-1), K (1.80 - 6.24 %), Ca (0.90 - 1.43 %), Mg (0.17 - 0.67 %), Al (49 - 378 mg kg-1), Ba (15.53 - 69.84 mg kg-1) and B (34.7 - 56.5 mg kg-1).
AB  - Određeni su profili elemenata, izraženi kao ukupan sadržaj glavnih komponenti i tragova (Cu, Zn,Mn, Fe,K,Ca, Mg,Al, Ba i B) u 8 biljnih droga, dobijenih iz biljaka familije Lamiacae. U analizi su primenjene metode: plamena atomska apsorpciona/ emisiona spektroskopija, atomska emisiona spektroskopija sa induktivno spregnutom plazmom i fluorescentna rendgenska analiza sa disperzijom energije. Diskutovane su prednosti i ograničenja primenjenih metoda analize. Metodološki postupak od pripreme uzoraka, do merenja proveren je i potvrđen primenom sertifikovanog standardnog materijala (NIST 1573a - Tomato leaves). Statističkom obradom rezultata dobijeni su procenti prinosa u opsegu 90.64 - 101.58 %. Rezultati kvalitativne analize ukazuju na veliki stepen sličnosti u sastavu neorganskih analita. Kvantitativnom analizom određen je sadržaj 10 elemenata i uočena različitost koncentracionih profila. Analizirane biljne droge sadrže: Cu (5.92 - 14.79 mg kg-1), Zn (15.0 - 43.0mg kg-1), Mn (25 - 111 mg kg-1), Fe (74 - 546 mg kg-1), K (1.80 - 6.24 %), Ca (0.90 - 1.43 %), Mg (0.17 - 0.67 %), Al (49 - 378 mg kg-1), Ba (15.53 - 69.84 mg kg-1) and B (34.7 - 56.5mg kg -1).
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Inorganic analysis of herbal drugs, Part I: Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae
T1  - Neorganska analiza biljnih droga, I deo - određivanje metala u biljnim drogama dobijenih iz biljaka familije Lamiacae
VL  - 70
IS  - 11
SP  - 1347
EP  - 1355
DO  - 10.2298/JSC0511347R
ER  - 

@article{
author = "Ražić, Slavica and Đogo, Svetlana and Slavković, Latinka and Popović, Aleksandar",
year = "2005",
abstract = "Elemental profiles of the total analyte content of major, minor and trace elements (Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and B) in 8 herbal drugs, originating from medicinal plants of the family Lamiacae, were determined. Flame atomic absorption/ emission spectroscopy (FAAS/FAES), inductively coupled plasma atomic emission spectroscopy (ICP-AES) and energy dispersive X-ray fluorescence (EDXRF) were applied, and the advantages and limitations of these techniques are also discussed. The whole procedure, from sample preparation via dissolution to the actual measurements, was validated by using CRM (NIST 1573a - Tomato leaves). The recovery values obtained were in the range 90.64 - 101.58 %. A high degree of similarity in their elemental profiles was noticed from the results of qualitative analysis, while quantitative analysis shows significant diversity due to the variety of the influencing sources. The medicinal plants investigated in this work contained Cu (5.92- 14.79 mg kg-1), Zn (15.0 - 43.0 mg kg-1), Mn (25 - 111 mg kg-1), Fe (74 - 546 mg kg-1), K (1.80 - 6.24 %), Ca (0.90 - 1.43 %), Mg (0.17 - 0.67 %), Al (49 - 378 mg kg-1), Ba (15.53 - 69.84 mg kg-1) and B (34.7 - 56.5 mg kg-1)., Određeni su profili elemenata, izraženi kao ukupan sadržaj glavnih komponenti i tragova (Cu, Zn,Mn, Fe,K,Ca, Mg,Al, Ba i B) u 8 biljnih droga, dobijenih iz biljaka familije Lamiacae. U analizi su primenjene metode: plamena atomska apsorpciona/ emisiona spektroskopija, atomska emisiona spektroskopija sa induktivno spregnutom plazmom i fluorescentna rendgenska analiza sa disperzijom energije. Diskutovane su prednosti i ograničenja primenjenih metoda analize. Metodološki postupak od pripreme uzoraka, do merenja proveren je i potvrđen primenom sertifikovanog standardnog materijala (NIST 1573a - Tomato leaves). Statističkom obradom rezultata dobijeni su procenti prinosa u opsegu 90.64 - 101.58 %. Rezultati kvalitativne analize ukazuju na veliki stepen sličnosti u sastavu neorganskih analita. Kvantitativnom analizom određen je sadržaj 10 elemenata i uočena različitost koncentracionih profila. Analizirane biljne droge sadrže: Cu (5.92 - 14.79 mg kg-1), Zn (15.0 - 43.0mg kg-1), Mn (25 - 111 mg kg-1), Fe (74 - 546 mg kg-1), K (1.80 - 6.24 %), Ca (0.90 - 1.43 %), Mg (0.17 - 0.67 %), Al (49 - 378 mg kg-1), Ba (15.53 - 69.84 mg kg-1) and B (34.7 - 56.5mg kg -1).",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Inorganic analysis of herbal drugs, Part I: Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae, Neorganska analiza biljnih droga, I deo - određivanje metala u biljnim drogama dobijenih iz biljaka familije Lamiacae",
volume = "70",
number = "11",
pages = "1347-1355",
doi = "10.2298/JSC0511347R"
}

Ražić, S., Đogo, S., Slavković, L.,& Popović, A.. (2005). Inorganic analysis of herbal drugs, Part I: Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 70(11), 1347-1355.
https://doi.org/10.2298/JSC0511347R

Ražić S, Đogo S, Slavković L, Popović A. Inorganic analysis of herbal drugs, Part I: Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae. in Journal of the Serbian Chemical Society. 2005;70(11):1347-1355.
doi:10.2298/JSC0511347R .

Ražić, Slavica, Đogo, Svetlana, Slavković, Latinka, Popović, Aleksandar, "Inorganic analysis of herbal drugs, Part I: Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae" in Journal of the Serbian Chemical Society, 70, no. 11 (2005):1347-1355,
https://doi.org/10.2298/JSC0511347R . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Onjia, Antonije
AU  - Đogo-Mračević, Svetlana
AU  - Slavković, Latinka
AU  - Popović, Aleksandar
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/577
AB  - The concentrations of Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and B in 26 herbal drugs of special importance in phytopharmacywere studied. Flame atomic absorption and emission spectrometry (FAAS, FAES), as well as inductively coupled plasma atomic emission spectrometry (ICP-AES), were applied in this work. The whole procedure, from sample preparation, via dissolution, to measurements, was validated by using CRM (NIST 1573a-tomato leaves), and the obtained recovery values are in the range from 91 to 102%. Drug samples originated from medicinal plants cultivated in Serbia contained Cu (4.47-14.08 mg kg(-1)), Zn (8.4-54.5 mg kg(-1)), Mn (9-155 mg kg(-1)), Fe (47-546 mg kg(-1)), K (0.20-6.24%), Ca (0.18-1.84%), Mg (0.13-1.09%), Al (16-416 mg kg(-1)), Ba (11.70-84.83 mg kg(-1)) and B (5.1-118.7 mg kg(-1)). In order to get a better insight into the elemental patterns, a common chemometric approach to data evaluation was used. Four significant factors identified by principal component analysis (PCA) were attributed partly to the significant influential sources and high mobility of some elements thus referring to potential anthropogenic contamination as well.
PB  - Elsevier Science BV, Amsterdam
T2  - Talanta
T1  - Determination of metal content in some herbal drugs - Empirical and chemometric approach
VL  - 67
IS  - 1
SP  - 233
EP  - 239
DO  - 10.1016/j.talanta.2005.03.023
ER  - 

@article{
author = "Ražić, Slavica and Onjia, Antonije and Đogo-Mračević, Svetlana and Slavković, Latinka and Popović, Aleksandar",
year = "2005",
abstract = "The concentrations of Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and B in 26 herbal drugs of special importance in phytopharmacywere studied. Flame atomic absorption and emission spectrometry (FAAS, FAES), as well as inductively coupled plasma atomic emission spectrometry (ICP-AES), were applied in this work. The whole procedure, from sample preparation, via dissolution, to measurements, was validated by using CRM (NIST 1573a-tomato leaves), and the obtained recovery values are in the range from 91 to 102%. Drug samples originated from medicinal plants cultivated in Serbia contained Cu (4.47-14.08 mg kg(-1)), Zn (8.4-54.5 mg kg(-1)), Mn (9-155 mg kg(-1)), Fe (47-546 mg kg(-1)), K (0.20-6.24%), Ca (0.18-1.84%), Mg (0.13-1.09%), Al (16-416 mg kg(-1)), Ba (11.70-84.83 mg kg(-1)) and B (5.1-118.7 mg kg(-1)). In order to get a better insight into the elemental patterns, a common chemometric approach to data evaluation was used. Four significant factors identified by principal component analysis (PCA) were attributed partly to the significant influential sources and high mobility of some elements thus referring to potential anthropogenic contamination as well.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Talanta",
title = "Determination of metal content in some herbal drugs - Empirical and chemometric approach",
volume = "67",
number = "1",
pages = "233-239",
doi = "10.1016/j.talanta.2005.03.023"
}

Ražić, S., Onjia, A., Đogo-Mračević, S., Slavković, L.,& Popović, A.. (2005). Determination of metal content in some herbal drugs - Empirical and chemometric approach. in Talanta
Elsevier Science BV, Amsterdam., 67(1), 233-239.
https://doi.org/10.1016/j.talanta.2005.03.023

Ražić S, Onjia A, Đogo-Mračević S, Slavković L, Popović A. Determination of metal content in some herbal drugs - Empirical and chemometric approach. in Talanta. 2005;67(1):233-239.
doi:10.1016/j.talanta.2005.03.023 .

Ražić, Slavica, Onjia, Antonije, Đogo-Mračević, Svetlana, Slavković, Latinka, Popović, Aleksandar, "Determination of metal content in some herbal drugs - Empirical and chemometric approach" in Talanta, 67, no. 1 (2005):233-239,
https://doi.org/10.1016/j.talanta.2005.03.023 . .