TY  - JOUR
AU  - Rašić, Jelena
AU  - Ivanović, Nevena
AU  - Anđelković, Marija
AU  - Nedeljković, Ivana
AU  - Nikolić, Ivan
AU  - Stojanović, Sava
AU  - Ristić-Medić, Danijela
AU  - Takić, Marija
AU  - Đorđević, Brižta
AU  - Dikić, Nenad
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3972
AB  - The aim of this study was to determine the ergogenic effects and the safety profile of a one-component higenamine supplement in female recreational athletes. Twelve recreational female basketball players (age 29–41 years, oxygen consumption (VO2max) > 30 ml⋅kg–1⋅min–1, with training > 5 h wk–1) were randomized either to the higenamine group, or to the placebo group for 3 weeks. In order to determine ergogenic effects and safety profile of higenamine administration, we assessed the following variables before and after 3 weeks of supplementation: anthropometric parameters, resting metabolic rate (RMR), exercise testing variables, serum free fatty acids (FFAs), blood pressure, enzyme activity, urea, lipid profile, and complete blood count. There were no differences between groups in anthropometric parameters, including basal metabolic rate (BMR), RMR and body fat [p = 0.706 (Cohen’s d 0.223), p = 0.169 (Cohen’s d 0.857), and p = 0.223 (Cohen’s d 0.750), respectively], FFAs [0.43 ± 0.03 vs. 0.54 ± 0.23, p = 0.206 (Cohen’s d 0.540)], neither significant differences in cardiopulmonary parameters after the intervention period. Furthermore, all measured outcome variables in the safety assessment were not significant, with values remaining stable during the intervention period for participants in both groups. This is the first study to document the effects and the safety profile of higenamine-based dietary supplements at a specified dose in female recreational athletes. Our data indicate that 21-day of supplementation with 75 mg higenamine would not result in improving cardiopulmonary exercise fitness and weight loss in female recreational athletes. Moreover, supplementation with 75 mg higenamine is safe and well-tolerated in younger recreational female athletes.
PB  - Frontiers Media S.A.
T2  - Frontiers in Psychology
T1  - Influence of Higenamine on Exercise Performance of Recreational Female Athletes: A Randomized Double-Blinded Placebo-Controlled Trial
VL  - 12
DO  - 10.3389/fpsyg.2021.633110
ER  - 

@article{
author = "Rašić, Jelena and Ivanović, Nevena and Anđelković, Marija and Nedeljković, Ivana and Nikolić, Ivan and Stojanović, Sava and Ristić-Medić, Danijela and Takić, Marija and Đorđević, Brižta and Dikić, Nenad",
year = "2021",
abstract = "The aim of this study was to determine the ergogenic effects and the safety profile of a one-component higenamine supplement in female recreational athletes. Twelve recreational female basketball players (age 29–41 years, oxygen consumption (VO2max) > 30 ml⋅kg–1⋅min–1, with training > 5 h wk–1) were randomized either to the higenamine group, or to the placebo group for 3 weeks. In order to determine ergogenic effects and safety profile of higenamine administration, we assessed the following variables before and after 3 weeks of supplementation: anthropometric parameters, resting metabolic rate (RMR), exercise testing variables, serum free fatty acids (FFAs), blood pressure, enzyme activity, urea, lipid profile, and complete blood count. There were no differences between groups in anthropometric parameters, including basal metabolic rate (BMR), RMR and body fat [p = 0.706 (Cohen’s d 0.223), p = 0.169 (Cohen’s d 0.857), and p = 0.223 (Cohen’s d 0.750), respectively], FFAs [0.43 ± 0.03 vs. 0.54 ± 0.23, p = 0.206 (Cohen’s d 0.540)], neither significant differences in cardiopulmonary parameters after the intervention period. Furthermore, all measured outcome variables in the safety assessment were not significant, with values remaining stable during the intervention period for participants in both groups. This is the first study to document the effects and the safety profile of higenamine-based dietary supplements at a specified dose in female recreational athletes. Our data indicate that 21-day of supplementation with 75 mg higenamine would not result in improving cardiopulmonary exercise fitness and weight loss in female recreational athletes. Moreover, supplementation with 75 mg higenamine is safe and well-tolerated in younger recreational female athletes.",
publisher = "Frontiers Media S.A.",
journal = "Frontiers in Psychology",
title = "Influence of Higenamine on Exercise Performance of Recreational Female Athletes: A Randomized Double-Blinded Placebo-Controlled Trial",
volume = "12",
doi = "10.3389/fpsyg.2021.633110"
}

Rašić, J., Ivanović, N., Anđelković, M., Nedeljković, I., Nikolić, I., Stojanović, S., Ristić-Medić, D., Takić, M., Đorđević, B.,& Dikić, N.. (2021). Influence of Higenamine on Exercise Performance of Recreational Female Athletes: A Randomized Double-Blinded Placebo-Controlled Trial. in Frontiers in Psychology
Frontiers Media S.A.., 12.
https://doi.org/10.3389/fpsyg.2021.633110

Rašić J, Ivanović N, Anđelković M, Nedeljković I, Nikolić I, Stojanović S, Ristić-Medić D, Takić M, Đorđević B, Dikić N. Influence of Higenamine on Exercise Performance of Recreational Female Athletes: A Randomized Double-Blinded Placebo-Controlled Trial. in Frontiers in Psychology. 2021;12.
doi:10.3389/fpsyg.2021.633110 .

Rašić, Jelena, Ivanović, Nevena, Anđelković, Marija, Nedeljković, Ivana, Nikolić, Ivan, Stojanović, Sava, Ristić-Medić, Danijela, Takić, Marija, Đorđević, Brižta, Dikić, Nenad, "Influence of Higenamine on Exercise Performance of Recreational Female Athletes: A Randomized Double-Blinded Placebo-Controlled Trial" in Frontiers in Psychology, 12 (2021),
https://doi.org/10.3389/fpsyg.2021.633110 . .

TY  - JOUR
AU  - Timić, Jasmina
AU  - Đuričić, Ivana
AU  - Ristić-Medić, Danijela K.
AU  - Šobajić, Slađana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3238
AB  - The rapid increase in the consumption of salty snack products has led to increased concern about their composition and nutritional value. The aim of this study was to investigate the fat content and fatty acid profile in salty snack products from the Serbian market. A total of 58 different snack products from 3 categories (Baked products, Chips & flips products, Cereal products) were analyzed. The fatty acid composition was determined using gas chromatography. Total fat content ranged from 3.1 % in expanded rice to 35.7 % in potato chips. Palmitic, oleic and linoleic acids constituted > 80 % of all fatty acids (FAs) in categories Baked products and Chips & flips. Linoleic acid was more abundant in the category Cereal products (15.5-49.3 %). The trans-FAs elaidic (C18:1 - 9t) and linolelaidic FAs (18: 2 - 9t, 12t) were identified in 66 % of the products. The flips products had the highest average t-FAs content (16.3 %), followed by flips group (9.3 %). Potential t-FAs intake from 100 g of analyzed products was in range 0.1-4.9 g. This study provided a large database on saturated fatty acids and t-FAs content in salty snack products and indicated that by consuming only one package of some products, the t-FAs intake could surpass the recommended maximum of 1 % of daily energy.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Fatty acid composition including trans-fatty acids in salty snack food from the Serbian market
VL  - 83
IS  - 6
SP  - 685
EP  - 698
DO  - 10.2298/JSC180207039T
ER  - 

@article{
author = "Timić, Jasmina and Đuričić, Ivana and Ristić-Medić, Danijela K. and Šobajić, Slađana",
year = "2018",
abstract = "The rapid increase in the consumption of salty snack products has led to increased concern about their composition and nutritional value. The aim of this study was to investigate the fat content and fatty acid profile in salty snack products from the Serbian market. A total of 58 different snack products from 3 categories (Baked products, Chips & flips products, Cereal products) were analyzed. The fatty acid composition was determined using gas chromatography. Total fat content ranged from 3.1 % in expanded rice to 35.7 % in potato chips. Palmitic, oleic and linoleic acids constituted > 80 % of all fatty acids (FAs) in categories Baked products and Chips & flips. Linoleic acid was more abundant in the category Cereal products (15.5-49.3 %). The trans-FAs elaidic (C18:1 - 9t) and linolelaidic FAs (18: 2 - 9t, 12t) were identified in 66 % of the products. The flips products had the highest average t-FAs content (16.3 %), followed by flips group (9.3 %). Potential t-FAs intake from 100 g of analyzed products was in range 0.1-4.9 g. This study provided a large database on saturated fatty acids and t-FAs content in salty snack products and indicated that by consuming only one package of some products, the t-FAs intake could surpass the recommended maximum of 1 % of daily energy.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Fatty acid composition including trans-fatty acids in salty snack food from the Serbian market",
volume = "83",
number = "6",
pages = "685-698",
doi = "10.2298/JSC180207039T"
}

Timić, J., Đuričić, I., Ristić-Medić, D. K.,& Šobajić, S.. (2018). Fatty acid composition including trans-fatty acids in salty snack food from the Serbian market. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 83(6), 685-698.
https://doi.org/10.2298/JSC180207039T

Timić J, Đuričić I, Ristić-Medić DK, Šobajić S. Fatty acid composition including trans-fatty acids in salty snack food from the Serbian market. in Journal of the Serbian Chemical Society. 2018;83(6):685-698.
doi:10.2298/JSC180207039T .

Timić, Jasmina, Đuričić, Ivana, Ristić-Medić, Danijela K., Šobajić, Slađana, "Fatty acid composition including trans-fatty acids in salty snack food from the Serbian market" in Journal of the Serbian Chemical Society, 83, no. 6 (2018):685-698,
https://doi.org/10.2298/JSC180207039T . .

TY  - JOUR
AU  - Peruničić-Peković, Gordana
AU  - Rasić, Zorica
AU  - Plješa, Steva
AU  - Šobajić, Slađana
AU  - Đuričić, Ivana
AU  - Maletić, Radojka
AU  - Ristić-Medić, Danijela K.
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/990
AB  - Aims: Nutrition as an aetiological factor participates a great deal in premature atherosclerosis in haemodialysis (HD) patients. The basic mechanisms of end-stage renal disease and premature atherosclerosis are connected with changes in cell functions at the membrane level. We investigated the red cell membrane fatty acids and the effects of fish oil supplements on nutritional status and inflammatory markers in HD patients. Methods: We examined 42 HD patients (mean age 55 +/- 8 years). The control group consisted of 16 healthy subjects of similar age and sex to the tested group. HD patients were administered supplements with 2.4 g of n-3 polyunsaturated fatty acids per day for 2 months. Before and after supplementation, we examined plasma lipids, cell membrane erythrocyte phospholipids content, serum albumin, haemoglobin, interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-alpha). Results: Baseline values in the tested group confirmed the presence of essential fatty acids deficiency. A statistically significant negative correlation between TNF-alpha and eicosapentaenoic acid (EPA) (r=-0.497; P  lt  0.05) and IL-6 and EPA (r=-468; P=0.03) was found in HD patients before supplementation. There was a significant increase in docosahexaenoic acids, high density lipoprotein cholesterol, plasma albumin, haemoglobin levels in HD patients after supplementation (P=0.0001). There was a significant increase in EPA (P=0.01) after treatment, and there was a significant decrease in inflammatory markers (IL-6 and TNF-alpha, P=0.0001) after supplementation in the tested group. Conclusion: A dietary regime with fish oil could be used in dialysis patients to slow down the development of atherosclerosis and improve nutritional parameters.
PB  - Wiley, Hoboken
T2  - Nephrology
T1  - Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients
VL  - 12
IS  - 4
SP  - 331
EP  - 336
DO  - 10.1111/j.1440-1797.2007.00777.x
ER  - 

@article{
author = "Peruničić-Peković, Gordana and Rasić, Zorica and Plješa, Steva and Šobajić, Slađana and Đuričić, Ivana and Maletić, Radojka and Ristić-Medić, Danijela K.",
year = "2007",
abstract = "Aims: Nutrition as an aetiological factor participates a great deal in premature atherosclerosis in haemodialysis (HD) patients. The basic mechanisms of end-stage renal disease and premature atherosclerosis are connected with changes in cell functions at the membrane level. We investigated the red cell membrane fatty acids and the effects of fish oil supplements on nutritional status and inflammatory markers in HD patients. Methods: We examined 42 HD patients (mean age 55 +/- 8 years). The control group consisted of 16 healthy subjects of similar age and sex to the tested group. HD patients were administered supplements with 2.4 g of n-3 polyunsaturated fatty acids per day for 2 months. Before and after supplementation, we examined plasma lipids, cell membrane erythrocyte phospholipids content, serum albumin, haemoglobin, interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-alpha). Results: Baseline values in the tested group confirmed the presence of essential fatty acids deficiency. A statistically significant negative correlation between TNF-alpha and eicosapentaenoic acid (EPA) (r=-0.497; P  lt  0.05) and IL-6 and EPA (r=-468; P=0.03) was found in HD patients before supplementation. There was a significant increase in docosahexaenoic acids, high density lipoprotein cholesterol, plasma albumin, haemoglobin levels in HD patients after supplementation (P=0.0001). There was a significant increase in EPA (P=0.01) after treatment, and there was a significant decrease in inflammatory markers (IL-6 and TNF-alpha, P=0.0001) after supplementation in the tested group. Conclusion: A dietary regime with fish oil could be used in dialysis patients to slow down the development of atherosclerosis and improve nutritional parameters.",
publisher = "Wiley, Hoboken",
journal = "Nephrology",
title = "Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients",
volume = "12",
number = "4",
pages = "331-336",
doi = "10.1111/j.1440-1797.2007.00777.x"
}

Peruničić-Peković, G., Rasić, Z., Plješa, S., Šobajić, S., Đuričić, I., Maletić, R.,& Ristić-Medić, D. K.. (2007). Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients. in Nephrology
Wiley, Hoboken., 12(4), 331-336.
https://doi.org/10.1111/j.1440-1797.2007.00777.x

Peruničić-Peković G, Rasić Z, Plješa S, Šobajić S, Đuričić I, Maletić R, Ristić-Medić DK. Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients. in Nephrology. 2007;12(4):331-336.
doi:10.1111/j.1440-1797.2007.00777.x .

Peruničić-Peković, Gordana, Rasić, Zorica, Plješa, Steva, Šobajić, Slađana, Đuričić, Ivana, Maletić, Radojka, Ristić-Medić, Danijela K., "Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients" in Nephrology, 12, no. 4 (2007):331-336,
https://doi.org/10.1111/j.1440-1797.2007.00777.x . .