Aleksić, Mirjana

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  • Aleksić, Mirjana (5)
  • Aleksić, Mirjana (1)
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Author's Bibliography

Salting-out thin-layer chromatography of several myorelaxants

Aleksić, Mirjana; Odović, Jadranka; Milojković-Opsenica, Dušanka; Tešić, Živoslav

(Research Inst Medicinal Plants, Budakalasz, 2003)

TY  - JOUR
AU  - Aleksić, Mirjana
AU  - Odović, Jadranka
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav
PY  - 2003
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/415
AB  - The chromatographic behavior of five myorelaxant drugs has been studied under the conditions used for salting-out thin-layer chromatography (SOTLC) on cellulose and alumina. For this purpose, aqueous ammonium sulfate solutions of different concentration were used as mobile phases. It was established that hR(F) values always decreased in parallel to increasing salt concentrations. When cellulose was used as adsorbent, a linear relationship was observed between the R-M values and the ammonium sulfate content of the mobile phase. Regression data of the plots obtained were used to determine the lipophilicity parameters R-M(0) and C-0. Lipophilicity determined in this way correlated with calculated log P values.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography - Modern TLC
T1  - Salting-out thin-layer chromatography of several myorelaxants
VL  - 16
IS  - 2
SP  - 144
EP  - 146
DO  - 10.1556/JPC.16.2003.2.11
ER  - 
@article{
author = "Aleksić, Mirjana and Odović, Jadranka and Milojković-Opsenica, Dušanka and Tešić, Živoslav",
year = "2003",
abstract = "The chromatographic behavior of five myorelaxant drugs has been studied under the conditions used for salting-out thin-layer chromatography (SOTLC) on cellulose and alumina. For this purpose, aqueous ammonium sulfate solutions of different concentration were used as mobile phases. It was established that hR(F) values always decreased in parallel to increasing salt concentrations. When cellulose was used as adsorbent, a linear relationship was observed between the R-M values and the ammonium sulfate content of the mobile phase. Regression data of the plots obtained were used to determine the lipophilicity parameters R-M(0) and C-0. Lipophilicity determined in this way correlated with calculated log P values.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Salting-out thin-layer chromatography of several myorelaxants",
volume = "16",
number = "2",
pages = "144-146",
doi = "10.1556/JPC.16.2003.2.11"
}
Aleksić, M., Odović, J., Milojković-Opsenica, D.,& Tešić, Ž.. (2003). Salting-out thin-layer chromatography of several myorelaxants. in Journal of Planar Chromatography - Modern TLC
Research Inst Medicinal Plants, Budakalasz., 16(2), 144-146.
https://doi.org/10.1556/JPC.16.2003.2.11
Aleksić M, Odović J, Milojković-Opsenica D, Tešić Ž. Salting-out thin-layer chromatography of several myorelaxants. in Journal of Planar Chromatography - Modern TLC. 2003;16(2):144-146.
doi:10.1556/JPC.16.2003.2.11 .
Aleksić, Mirjana, Odović, Jadranka, Milojković-Opsenica, Dušanka, Tešić, Živoslav, "Salting-out thin-layer chromatography of several myorelaxants" in Journal of Planar Chromatography - Modern TLC, 16, no. 2 (2003):144-146,
https://doi.org/10.1556/JPC.16.2003.2.11 . .
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Estimation of the hydrophobicity of antimycotic compounds by planar chromatography

Aleksić, Mirjana; Erić, Slavica; Agbaba, Danica; Odović, Jadranka; Milojković-Opsenica, Dušanka; Tesić, I

(Research Inst Medicinal Plants, Budakalasz, 2002)

TY  - JOUR
AU  - Aleksić, Mirjana
AU  - Erić, Slavica
AU  - Agbaba, Danica
AU  - Odović, Jadranka
AU  - Milojković-Opsenica, Dušanka
AU  - Tesić, I
PY  - 2002
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/342
AB  - The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography - Modern TLC
T1  - Estimation of the hydrophobicity of antimycotic compounds by planar chromatography
VL  - 15
IS  - 6
SP  - 414
EP  - 417
DO  - 10.1556/JPC.15.2002.6.4
ER  - 
@article{
author = "Aleksić, Mirjana and Erić, Slavica and Agbaba, Danica and Odović, Jadranka and Milojković-Opsenica, Dušanka and Tesić, I",
year = "2002",
abstract = "The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Estimation of the hydrophobicity of antimycotic compounds by planar chromatography",
volume = "15",
number = "6",
pages = "414-417",
doi = "10.1556/JPC.15.2002.6.4"
}
Aleksić, M., Erić, S., Agbaba, D., Odović, J., Milojković-Opsenica, D.,& Tesić, I.. (2002). Estimation of the hydrophobicity of antimycotic compounds by planar chromatography. in Journal of Planar Chromatography - Modern TLC
Research Inst Medicinal Plants, Budakalasz., 15(6), 414-417.
https://doi.org/10.1556/JPC.15.2002.6.4
Aleksić M, Erić S, Agbaba D, Odović J, Milojković-Opsenica D, Tesić I. Estimation of the hydrophobicity of antimycotic compounds by planar chromatography. in Journal of Planar Chromatography - Modern TLC. 2002;15(6):414-417.
doi:10.1556/JPC.15.2002.6.4 .
Aleksić, Mirjana, Erić, Slavica, Agbaba, Danica, Odović, Jadranka, Milojković-Opsenica, Dušanka, Tesić, I, "Estimation of the hydrophobicity of antimycotic compounds by planar chromatography" in Journal of Planar Chromatography - Modern TLC, 15, no. 6 (2002):414-417,
https://doi.org/10.1556/JPC.15.2002.6.4 . .
17
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HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets

Franeta, JT; Agbaba, Danica; Erić, Slavica; Pavkov, S; Aleksić, Mirjana ; Vladimirov, S

(Elsevier Science Sa, Lausanne, 2002)

TY  - JOUR
AU  - Franeta, JT
AU  - Agbaba, Danica
AU  - Erić, Slavica
AU  - Pavkov, S
AU  - Aleksić, Mirjana

AU  - Vladimirov, S
PY  - 2002
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/320
AB  - This paper present a HPLC method for simultaneous determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets, using chromatographic system consisting a Bio Rad 18 01 solvent pump, Rheodine 71 25 injector and Bio Rad 18 01 UV-Vis Detector. Separation was achieved using Bio SiL HL C 18, 5 mum, 250 x 4.6 mm column. Mixture of acetonitrile-water (25:75 v/v) adjusted to pH 2.5 with phosphoric acid was used as a mobile phase at a flow rate of 2.0 ml(-1) min UV detection was at 207 nm range 0.01 AUFS. Under the same conditions it was possible to determine the level of salicylic acid. The chromatographic parameters such as retention times, capacity factor, peak asymmetry, selectivity factor and resolution factor was determined. The validation parameters: linearity (r > 0.998), intra-day precision (RSD: 0.36-1.89%) and inter-day precision (RSD: 0.58-2.18%), sensitivity (LOD: 9 x 10(-5)-1.7 x 10(-4) mg ml(-1) and LOQ: 2.5 x 10(-4)-5.6 x 10(-4) mg ml(-1)), accuracy (recoveries: 98.35-99.14%) and reproducibility (recovery values: 98.74-102.08% for acetylsalicylic acid, 99.93-102.11% for paracetamol, 98.25-102.12% for caffeine and 98.15-102.3% for phenobarbital) (RSD: 1.21-1.85%) were found to be satisfactory. The proposed HPLC method has been applied for the determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in Malophenum tablets. The obtained RSD values were within 0.99-1.21%. The developed method is rapid and sensitive and therefore suitable for routine control of these drugs in dosage form.
PB  - Elsevier Science Sa, Lausanne
T2  - Farmaco
T1  - HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets
VL  - 57
IS  - 9
SP  - 709
EP  - 713
DO  - 10.1016/S0014-827X(02)01265-X
ER  - 
@article{
author = "Franeta, JT and Agbaba, Danica and Erić, Slavica and Pavkov, S and Aleksić, Mirjana
 and Vladimirov, S",
year = "2002",
abstract = "This paper present a HPLC method for simultaneous determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets, using chromatographic system consisting a Bio Rad 18 01 solvent pump, Rheodine 71 25 injector and Bio Rad 18 01 UV-Vis Detector. Separation was achieved using Bio SiL HL C 18, 5 mum, 250 x 4.6 mm column. Mixture of acetonitrile-water (25:75 v/v) adjusted to pH 2.5 with phosphoric acid was used as a mobile phase at a flow rate of 2.0 ml(-1) min UV detection was at 207 nm range 0.01 AUFS. Under the same conditions it was possible to determine the level of salicylic acid. The chromatographic parameters such as retention times, capacity factor, peak asymmetry, selectivity factor and resolution factor was determined. The validation parameters: linearity (r > 0.998), intra-day precision (RSD: 0.36-1.89%) and inter-day precision (RSD: 0.58-2.18%), sensitivity (LOD: 9 x 10(-5)-1.7 x 10(-4) mg ml(-1) and LOQ: 2.5 x 10(-4)-5.6 x 10(-4) mg ml(-1)), accuracy (recoveries: 98.35-99.14%) and reproducibility (recovery values: 98.74-102.08% for acetylsalicylic acid, 99.93-102.11% for paracetamol, 98.25-102.12% for caffeine and 98.15-102.3% for phenobarbital) (RSD: 1.21-1.85%) were found to be satisfactory. The proposed HPLC method has been applied for the determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in Malophenum tablets. The obtained RSD values were within 0.99-1.21%. The developed method is rapid and sensitive and therefore suitable for routine control of these drugs in dosage form.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Farmaco",
title = "HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets",
volume = "57",
number = "9",
pages = "709-713",
doi = "10.1016/S0014-827X(02)01265-X"
}
Franeta, J., Agbaba, D., Erić, S., Pavkov, S., Aleksić, M.,& Vladimirov, S.. (2002). HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets. in Farmaco
Elsevier Science Sa, Lausanne., 57(9), 709-713.
https://doi.org/10.1016/S0014-827X(02)01265-X
Franeta J, Agbaba D, Erić S, Pavkov S, Aleksić M, Vladimirov S. HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets. in Farmaco. 2002;57(9):709-713.
doi:10.1016/S0014-827X(02)01265-X .
Franeta, JT, Agbaba, Danica, Erić, Slavica, Pavkov, S, Aleksić, Mirjana
, Vladimirov, S, "HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets" in Farmaco, 57, no. 9 (2002):709-713,
https://doi.org/10.1016/S0014-827X(02)01265-X . .
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181

Quantitative analysis of analgoantipyretics in dosage form using planar chromatography

Franeta, JT; Agbaba, Danica; Erić, Slavica; Pavkov, SP; Vladimirov, SD; Aleksić, Mirjana

(Pergamon-Elsevier Science Ltd, Oxford, 2001)

TY  - JOUR
AU  - Franeta, JT
AU  - Agbaba, Danica
AU  - Erić, Slavica
AU  - Pavkov, SP
AU  - Vladimirov, SD
AU  - Aleksić, Mirjana
PY  - 2001
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/292
AB  - In the therapy of pain of weaker genesis, frequently used drugs usually represent a mix of analgoantipyretics of different chemical structures, mostly derivatives of salicylic acid, pyrazolone and p-aminophenol as well as derivatives of propionic and acetylsalicylic acid. For the determination of these drugs, different chromatographic methods have been applied, mostly HPLC, due to the the lower polarity (pyrazolones derivatives) and thermolability, as well as nonvolatility of compounds investigated. TLC method, considering advantages which include simplicity, reasonable sensitivity, rapidity, excellent resolving power and low cost has been successfully explored for the determination of analgoantipyretic compounds, The aim of this work was to develop a simple and rapid HPTLC method for the determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbitone in dosage form. The determination of analgoantipyretics were performed on pre-coated HPTLC silica gel plates (10 x 20 cm(2)) by development in the mobile phase dichlormethanethyl acetate-cyclohexane-isopropanol-0.1 M HCL formic acid (9:8:3:1.5:0.2:0.2 v/v/v/v/v/v). Migration distances (68.5 + 0.2 mm, 54.1 + 0.1 mm, 36.4 + 0.14 mtn and 85.9 + 0.11 mm for acetylsalicylic acid, paracetamol. caffeine and phenobarbitone, respectively) with low RSD values (0.13-0.39%) showed a satisfactory reproductivity of the chromatographic system. TLC scanner. was used for direct evaluation of the chromatograms in the reflectance/absorbance mode. Established calibration curves (r > 0.999), precision (0.3-1.02%) and detection limits, as well as recovery values (96.51 98.1%) were validated and found to be satisfactory. The method was found to be reproducible and convenient for the quantitative analysis of compounds investigated in their dosage forms.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Quantitative analysis of analgoantipyretics in dosage form using planar chromatography
VL  - 24
IS  - 5-6
SP  - 1169
EP  - 1173
DO  - 10.1016/S0731-7085(00)00579-3
ER  - 
@article{
author = "Franeta, JT and Agbaba, Danica and Erić, Slavica and Pavkov, SP and Vladimirov, SD and Aleksić, Mirjana",
year = "2001",
abstract = "In the therapy of pain of weaker genesis, frequently used drugs usually represent a mix of analgoantipyretics of different chemical structures, mostly derivatives of salicylic acid, pyrazolone and p-aminophenol as well as derivatives of propionic and acetylsalicylic acid. For the determination of these drugs, different chromatographic methods have been applied, mostly HPLC, due to the the lower polarity (pyrazolones derivatives) and thermolability, as well as nonvolatility of compounds investigated. TLC method, considering advantages which include simplicity, reasonable sensitivity, rapidity, excellent resolving power and low cost has been successfully explored for the determination of analgoantipyretic compounds, The aim of this work was to develop a simple and rapid HPTLC method for the determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbitone in dosage form. The determination of analgoantipyretics were performed on pre-coated HPTLC silica gel plates (10 x 20 cm(2)) by development in the mobile phase dichlormethanethyl acetate-cyclohexane-isopropanol-0.1 M HCL formic acid (9:8:3:1.5:0.2:0.2 v/v/v/v/v/v). Migration distances (68.5 + 0.2 mm, 54.1 + 0.1 mm, 36.4 + 0.14 mtn and 85.9 + 0.11 mm for acetylsalicylic acid, paracetamol. caffeine and phenobarbitone, respectively) with low RSD values (0.13-0.39%) showed a satisfactory reproductivity of the chromatographic system. TLC scanner. was used for direct evaluation of the chromatograms in the reflectance/absorbance mode. Established calibration curves (r > 0.999), precision (0.3-1.02%) and detection limits, as well as recovery values (96.51 98.1%) were validated and found to be satisfactory. The method was found to be reproducible and convenient for the quantitative analysis of compounds investigated in their dosage forms.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Quantitative analysis of analgoantipyretics in dosage form using planar chromatography",
volume = "24",
number = "5-6",
pages = "1169-1173",
doi = "10.1016/S0731-7085(00)00579-3"
}
Franeta, J., Agbaba, D., Erić, S., Pavkov, S., Vladimirov, S.,& Aleksić, M.. (2001). Quantitative analysis of analgoantipyretics in dosage form using planar chromatography. in Journal of Pharmaceutical and Biomedical Analysis
Pergamon-Elsevier Science Ltd, Oxford., 24(5-6), 1169-1173.
https://doi.org/10.1016/S0731-7085(00)00579-3
Franeta J, Agbaba D, Erić S, Pavkov S, Vladimirov S, Aleksić M. Quantitative analysis of analgoantipyretics in dosage form using planar chromatography. in Journal of Pharmaceutical and Biomedical Analysis. 2001;24(5-6):1169-1173.
doi:10.1016/S0731-7085(00)00579-3 .
Franeta, JT, Agbaba, Danica, Erić, Slavica, Pavkov, SP, Vladimirov, SD, Aleksić, Mirjana, "Quantitative analysis of analgoantipyretics in dosage form using planar chromatography" in Journal of Pharmaceutical and Biomedical Analysis, 24, no. 5-6 (2001):1169-1173,
https://doi.org/10.1016/S0731-7085(00)00579-3 . .
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The high-performance thin-layer chromatographic determination of dexamethasone and xylometazoline in nasal drops containing different preservatives

Agbaba, Danica; Milojević, Z; Erić, Slavica; Aleksić, Mirjana; Marković, G; Solujić, M

(Springer Nature, 2001)

TY  - JOUR
AU  - Agbaba, Danica
AU  - Milojević, Z
AU  - Erić, Slavica
AU  - Aleksić, Mirjana
AU  - Marković, G
AU  - Solujić, M
PY  - 2001
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/298
AB  - A simple and reliable HPTLC method has been developed and validated for the determination of dexamethasone (as the sodium phosphate salt) and xylometazoline (as the chloride). Assay of the compounds was performed on silica gel HPTLC plates with spherical particles by development with the mobile phase ethyl acetate-acetonitrile-diethylamine-water, 3 + 3 + 1 + 1 (v/v). A TLC scanner set at lambda = 240 nm was used for direct evaluation of chromatograms in reflectance/absorbance mode. The validation data linearity (R > 0.996), precision (RSD = 1.67-2.77%), accuracy (recovery = 95.95-100.69%) and LOD and LOQ (ng levels) were determined and found to be satisfactory. Assay of dexamethasone and xylometazoline in nasal drops was performed simultaneously with assay of preservatives such as methyl para-hydroxybenzoate. The effect of the most commonly used preservative, benzalkonium chloride on the concentrations of active substances was investigated; it was found that this compound led to a significant reduction of the dexamethasone sodium phosphate content of nasal drops.
PB  - Springer Nature
T2  - Journal of Planar Chromatography - Modern TLC
T1  - The high-performance thin-layer chromatographic determination of dexamethasone and xylometazoline in nasal drops containing different preservatives
VL  - 14
IS  - 5
SP  - 322
EP  - 325
DO  - 10.1556/JPC.14.2001.5.3
UR  - https://hdl.handle.net/21.15107/rcub_farfar_298
ER  - 
@article{
author = "Agbaba, Danica and Milojević, Z and Erić, Slavica and Aleksić, Mirjana and Marković, G and Solujić, M",
year = "2001",
abstract = "A simple and reliable HPTLC method has been developed and validated for the determination of dexamethasone (as the sodium phosphate salt) and xylometazoline (as the chloride). Assay of the compounds was performed on silica gel HPTLC plates with spherical particles by development with the mobile phase ethyl acetate-acetonitrile-diethylamine-water, 3 + 3 + 1 + 1 (v/v). A TLC scanner set at lambda = 240 nm was used for direct evaluation of chromatograms in reflectance/absorbance mode. The validation data linearity (R > 0.996), precision (RSD = 1.67-2.77%), accuracy (recovery = 95.95-100.69%) and LOD and LOQ (ng levels) were determined and found to be satisfactory. Assay of dexamethasone and xylometazoline in nasal drops was performed simultaneously with assay of preservatives such as methyl para-hydroxybenzoate. The effect of the most commonly used preservative, benzalkonium chloride on the concentrations of active substances was investigated; it was found that this compound led to a significant reduction of the dexamethasone sodium phosphate content of nasal drops.",
publisher = "Springer Nature",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "The high-performance thin-layer chromatographic determination of dexamethasone and xylometazoline in nasal drops containing different preservatives",
volume = "14",
number = "5",
pages = "322-325",
doi = "10.1556/JPC.14.2001.5.3",
url = "https://hdl.handle.net/21.15107/rcub_farfar_298"
}
Agbaba, D., Milojević, Z., Erić, S., Aleksić, M., Marković, G.,& Solujić, M.. (2001). The high-performance thin-layer chromatographic determination of dexamethasone and xylometazoline in nasal drops containing different preservatives. in Journal of Planar Chromatography - Modern TLC
Springer Nature., 14(5), 322-325.
https://doi.org/10.1556/JPC.14.2001.5.3
https://hdl.handle.net/21.15107/rcub_farfar_298
Agbaba D, Milojević Z, Erić S, Aleksić M, Marković G, Solujić M. The high-performance thin-layer chromatographic determination of dexamethasone and xylometazoline in nasal drops containing different preservatives. in Journal of Planar Chromatography - Modern TLC. 2001;14(5):322-325.
doi:10.1556/JPC.14.2001.5.3
https://hdl.handle.net/21.15107/rcub_farfar_298 .
Agbaba, Danica, Milojević, Z, Erić, Slavica, Aleksić, Mirjana, Marković, G, Solujić, M, "The high-performance thin-layer chromatographic determination of dexamethasone and xylometazoline in nasal drops containing different preservatives" in Journal of Planar Chromatography - Modern TLC, 14, no. 5 (2001):322-325,
https://doi.org/10.1556/JPC.14.2001.5.3 .,
https://hdl.handle.net/21.15107/rcub_farfar_298 .
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11

Salting-out thin-layer chromatography of some angiotensin converting enzyme inhibitors on different sorbents

Aleksić, Mirjana; Agbaba, Danica; Milojković-Opsenica, Dušanka; Tešić, Živoslav

(Vieweg, Wiesbaden, 2001)

TY  - JOUR
AU  - Aleksić, Mirjana
AU  - Agbaba, Danica
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav
PY  - 2001
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/285
AB  - Chromatographic behaviour of six anti hypertensive drugs from the class of ACE inhibitors was studied under conditions of salting-out thin-layer chromatography on silica-gel, cellulose and polyacrylonitrile (PANS) as sorbents. For this purpose, different concentrations of aqueous ammonium sulphate solutions were used as solvents. In all cases studied, it was established that hR(F) values decrease with increasing salt concentrations in the chromatographic solvent Systems used. In addition, a linear relationship of the corresponding R-M values and ammonium sulphate content in the solvent was observed. To explain these results, a separation mechanism based on hydrophobic interaction between the sorbend and sorbent is proposed.
PB  - Vieweg, Wiesbaden
T2  - Chromatographia
T1  - Salting-out thin-layer chromatography of some angiotensin converting enzyme inhibitors on different sorbents
VL  - 53
IS  - SPEC. ISS
DO  - 10.1007/BF02490373
ER  - 
@article{
author = "Aleksić, Mirjana and Agbaba, Danica and Milojković-Opsenica, Dušanka and Tešić, Živoslav",
year = "2001",
abstract = "Chromatographic behaviour of six anti hypertensive drugs from the class of ACE inhibitors was studied under conditions of salting-out thin-layer chromatography on silica-gel, cellulose and polyacrylonitrile (PANS) as sorbents. For this purpose, different concentrations of aqueous ammonium sulphate solutions were used as solvents. In all cases studied, it was established that hR(F) values decrease with increasing salt concentrations in the chromatographic solvent Systems used. In addition, a linear relationship of the corresponding R-M values and ammonium sulphate content in the solvent was observed. To explain these results, a separation mechanism based on hydrophobic interaction between the sorbend and sorbent is proposed.",
publisher = "Vieweg, Wiesbaden",
journal = "Chromatographia",
title = "Salting-out thin-layer chromatography of some angiotensin converting enzyme inhibitors on different sorbents",
volume = "53",
number = "SPEC. ISS",
doi = "10.1007/BF02490373"
}
Aleksić, M., Agbaba, D., Milojković-Opsenica, D.,& Tešić, Ž.. (2001). Salting-out thin-layer chromatography of some angiotensin converting enzyme inhibitors on different sorbents. in Chromatographia
Vieweg, Wiesbaden., 53(SPEC. ISS).
https://doi.org/10.1007/BF02490373
Aleksić M, Agbaba D, Milojković-Opsenica D, Tešić Ž. Salting-out thin-layer chromatography of some angiotensin converting enzyme inhibitors on different sorbents. in Chromatographia. 2001;53(SPEC. ISS).
doi:10.1007/BF02490373 .
Aleksić, Mirjana, Agbaba, Danica, Milojković-Opsenica, Dušanka, Tešić, Živoslav, "Salting-out thin-layer chromatography of some angiotensin converting enzyme inhibitors on different sorbents" in Chromatographia, 53, no. SPEC. ISS (2001),
https://doi.org/10.1007/BF02490373 . .
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