Maksimović, Nataša

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  • Maksimović, Nataša (2)
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Antimicrobial utilization and resistance in Pseudomonas aeruginosa using segmented regression analysis: a comparative study between Serbia and eight European Countries

Tomić, Tanja; Henman, Martin; Tadić, Ivana; Antić-Stanković, Jelena; Santric Milicević, Milena; Maksimović, Nataša; Odalović, Marina

(Springer, 2023)

TY  - JOUR
AU  - Tomić, Tanja
AU  - Henman, Martin
AU  - Tadić, Ivana
AU  - Antić-Stanković, Jelena
AU  - Santric Milicević, Milena
AU  - Maksimović, Nataša
AU  - Odalović, Marina
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4832
AB  - Background In Europe, Serbia occupies a high position in antibiotic utilization and antimicrobial resistance (AMR). Aim The aim was to analyse utilization trends of meropenem, ceftazidime, aminoglycosides, piperacillin/tazobactam and fluoroquinolones (2006–2020), and the reported AMR in Pseudomonas aeruginosa (2013–2020) in Serbia and to compare with data from eight European countries (2015–2020). Method Joinpoint regression was used to analyse antibiotic utilization data (2006–2020) and the reported AMR in Pseu- domonas aeruginosa (2013–2020). Data sources were relevant national and international institutions. Antibiotic utilization and AMR in Pseudomonas aeruginosa data in Serbia were compared with eight European countries. Results There was a significantly increased trend for ceftazidime utilization and reported resistance in Pseudomonas aer- uginosa, Serbia (p < 0.05) (2018–2020). For ceftazidime, piperacillin/tazobactam, and fluoroquinolones resistances in Pseu- domonas aeruginosa an increased trend was observed, Serbia (2013–2020). A decrease in both the utilization of aminogly- cosides, Serbia (p < 0.05) (2006–2018) and contemporaneous Pseudomonas aeruginosa resistance (p > 0.05) was detected. Fluoroquinolone utilization (2015–2020) was highest in Serbia compared to Netherlands and Finland, 310 and 305% higher, similar compared to Romania, and 2% less compared to Montenegro. Aminoglycosides (2015–2020) were 2550 and 783% more used in Serbia compared to Finland and Netherlands, and 38% less regarding Montenegro. The highest percentage of Pseudomonas aeruginosa resistance was in Romania and Serbia (2015–2020). Conclusion The use of piperacillin/tazobactam, ceftazidime and fluoroquinolones should be carefully monitored in clinical practice due to increased Pseudomonas aeruginosa resistance. The level of utilization and AMR in Pseudomonas aeruginosa is still high in Serbia compared to other European countries.
PB  - Springer
T2  - International Journal of Clinical Pharmacy
T1  - Antimicrobial utilization and resistance in Pseudomonas aeruginosa using segmented regression analysis: a comparative study between Serbia and eight European Countries
DO  - 10.1007/s11096-023-01603-y
ER  - 
@article{
author = "Tomić, Tanja and Henman, Martin and Tadić, Ivana and Antić-Stanković, Jelena and Santric Milicević, Milena and Maksimović, Nataša and Odalović, Marina",
year = "2023",
abstract = "Background In Europe, Serbia occupies a high position in antibiotic utilization and antimicrobial resistance (AMR). Aim The aim was to analyse utilization trends of meropenem, ceftazidime, aminoglycosides, piperacillin/tazobactam and fluoroquinolones (2006–2020), and the reported AMR in Pseudomonas aeruginosa (2013–2020) in Serbia and to compare with data from eight European countries (2015–2020). Method Joinpoint regression was used to analyse antibiotic utilization data (2006–2020) and the reported AMR in Pseu- domonas aeruginosa (2013–2020). Data sources were relevant national and international institutions. Antibiotic utilization and AMR in Pseudomonas aeruginosa data in Serbia were compared with eight European countries. Results There was a significantly increased trend for ceftazidime utilization and reported resistance in Pseudomonas aer- uginosa, Serbia (p < 0.05) (2018–2020). For ceftazidime, piperacillin/tazobactam, and fluoroquinolones resistances in Pseu- domonas aeruginosa an increased trend was observed, Serbia (2013–2020). A decrease in both the utilization of aminogly- cosides, Serbia (p < 0.05) (2006–2018) and contemporaneous Pseudomonas aeruginosa resistance (p > 0.05) was detected. Fluoroquinolone utilization (2015–2020) was highest in Serbia compared to Netherlands and Finland, 310 and 305% higher, similar compared to Romania, and 2% less compared to Montenegro. Aminoglycosides (2015–2020) were 2550 and 783% more used in Serbia compared to Finland and Netherlands, and 38% less regarding Montenegro. The highest percentage of Pseudomonas aeruginosa resistance was in Romania and Serbia (2015–2020). Conclusion The use of piperacillin/tazobactam, ceftazidime and fluoroquinolones should be carefully monitored in clinical practice due to increased Pseudomonas aeruginosa resistance. The level of utilization and AMR in Pseudomonas aeruginosa is still high in Serbia compared to other European countries.",
publisher = "Springer",
journal = "International Journal of Clinical Pharmacy",
title = "Antimicrobial utilization and resistance in Pseudomonas aeruginosa using segmented regression analysis: a comparative study between Serbia and eight European Countries",
doi = "10.1007/s11096-023-01603-y"
}
Tomić, T., Henman, M., Tadić, I., Antić-Stanković, J., Santric Milicević, M., Maksimović, N.,& Odalović, M.. (2023). Antimicrobial utilization and resistance in Pseudomonas aeruginosa using segmented regression analysis: a comparative study between Serbia and eight European Countries. in International Journal of Clinical Pharmacy
Springer..
https://doi.org/10.1007/s11096-023-01603-y
Tomić T, Henman M, Tadić I, Antić-Stanković J, Santric Milicević M, Maksimović N, Odalović M. Antimicrobial utilization and resistance in Pseudomonas aeruginosa using segmented regression analysis: a comparative study between Serbia and eight European Countries. in International Journal of Clinical Pharmacy. 2023;.
doi:10.1007/s11096-023-01603-y .
Tomić, Tanja, Henman, Martin, Tadić, Ivana, Antić-Stanković, Jelena, Santric Milicević, Milena, Maksimović, Nataša, Odalović, Marina, "Antimicrobial utilization and resistance in Pseudomonas aeruginosa using segmented regression analysis: a comparative study between Serbia and eight European Countries" in International Journal of Clinical Pharmacy (2023),
https://doi.org/10.1007/s11096-023-01603-y . .
1

Attitudes of Nurses Toward Organ Donation in Serbia

Vlaisavljević, Željko; Janković, Slobodan; Maksimović, Nataša; Ćulafić, Milica; Štulić, Miloš; Milovanović, Tamara; Oluić, Branislav

(Elsevier USA, 2020)

TY  - JOUR
AU  - Vlaisavljević, Željko
AU  - Janković, Slobodan
AU  - Maksimović, Nataša
AU  - Ćulafić, Milica
AU  - Štulić, Miloš
AU  - Milovanović, Tamara
AU  - Oluić, Branislav
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3559
AB  - Objective. Nurses represent the key persons in the process of organ donation, acting as intermediaries between the patient and the family of a potential donor. The aim of this study was to analyze the factors influencing the attitudes of nurses toward bequeathing and organ and tissue donation. Methods. The research was designed as a cross-sectional study from November 2013 to November 2014 and included a sample of 264 nurses employed in the health system of Serbia. Data were collected using a specific questionnaire of 18 questions referring to the information on sociodemographic characteristics and the knowledge of organ donation. Results. The investigation enrolled 264 participants, of which 78% were women. The majority of study subjects had secondary medical education (64.4%), lived in an urban area (82.6%), were married (56.4%), and were predominantly Orthodox (87.1%) with their work experience between 5 and 10 years (29.9%) and 10 to 20 years (29.5%). The average knowledge score concerning organ donation was 29.03 (SD, 2.33; range, 23-34). There was a statistically significant difference in the scores between 2 groups formed according the length of service (P < .001) and the level of education (P ¼ .019), which showed the strongest influence on nurses’ attitudes toward donation. Conclusion. This investigation showed that nurses did not express strong positive attitude toward this issue. Further education of nurses in the Serbian health care system focusing on transplantation and bequeathing of organs and tissues are warranted. N
PB  - Elsevier USA
T2  - Transplantation Proceedings
T1  - Attitudes of Nurses Toward Organ Donation in Serbia
VL  - 52
IS  - 3
SP  - 673
EP  - 679
DO  - 10.1016/j.transproceed.2020.01.031
ER  - 
@article{
author = "Vlaisavljević, Željko and Janković, Slobodan and Maksimović, Nataša and Ćulafić, Milica and Štulić, Miloš and Milovanović, Tamara and Oluić, Branislav",
year = "2020",
abstract = "Objective. Nurses represent the key persons in the process of organ donation, acting as intermediaries between the patient and the family of a potential donor. The aim of this study was to analyze the factors influencing the attitudes of nurses toward bequeathing and organ and tissue donation. Methods. The research was designed as a cross-sectional study from November 2013 to November 2014 and included a sample of 264 nurses employed in the health system of Serbia. Data were collected using a specific questionnaire of 18 questions referring to the information on sociodemographic characteristics and the knowledge of organ donation. Results. The investigation enrolled 264 participants, of which 78% were women. The majority of study subjects had secondary medical education (64.4%), lived in an urban area (82.6%), were married (56.4%), and were predominantly Orthodox (87.1%) with their work experience between 5 and 10 years (29.9%) and 10 to 20 years (29.5%). The average knowledge score concerning organ donation was 29.03 (SD, 2.33; range, 23-34). There was a statistically significant difference in the scores between 2 groups formed according the length of service (P < .001) and the level of education (P ¼ .019), which showed the strongest influence on nurses’ attitudes toward donation. Conclusion. This investigation showed that nurses did not express strong positive attitude toward this issue. Further education of nurses in the Serbian health care system focusing on transplantation and bequeathing of organs and tissues are warranted. N",
publisher = "Elsevier USA",
journal = "Transplantation Proceedings",
title = "Attitudes of Nurses Toward Organ Donation in Serbia",
volume = "52",
number = "3",
pages = "673-679",
doi = "10.1016/j.transproceed.2020.01.031"
}
Vlaisavljević, Ž., Janković, S., Maksimović, N., Ćulafić, M., Štulić, M., Milovanović, T.,& Oluić, B.. (2020). Attitudes of Nurses Toward Organ Donation in Serbia. in Transplantation Proceedings
Elsevier USA., 52(3), 673-679.
https://doi.org/10.1016/j.transproceed.2020.01.031
Vlaisavljević Ž, Janković S, Maksimović N, Ćulafić M, Štulić M, Milovanović T, Oluić B. Attitudes of Nurses Toward Organ Donation in Serbia. in Transplantation Proceedings. 2020;52(3):673-679.
doi:10.1016/j.transproceed.2020.01.031 .
Vlaisavljević, Željko, Janković, Slobodan, Maksimović, Nataša, Ćulafić, Milica, Štulić, Miloš, Milovanović, Tamara, Oluić, Branislav, "Attitudes of Nurses Toward Organ Donation in Serbia" in Transplantation Proceedings, 52, no. 3 (2020):673-679,
https://doi.org/10.1016/j.transproceed.2020.01.031 . .
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