Aleksić, Mirjana

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  • Aleksić, Mirjana (1)
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Author's Bibliography

Examination of the hydrophobicity of ACE inhibitors and their active metabolites by salting-out thin-layer chromatography

Odović, Jadranka; Stojimirović, Biljana; Aleksić, Mirjana; Milojković-Opsenica, Dušanka; Tešić, Živoslav

(Research Inst Medicinal Plants, Budakalasz, 2005)

TY  - JOUR
AU  - Odović, Jadranka
AU  - Stojimirović, Biljana
AU  - Aleksić, Mirjana
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/584
AB  - The behavior of five ACE inhibitors and their active degradation products in salting-out thin-layer chromatography (SO TLC) has been examined on silica gel, cellulose, and polyacrylonitrile (PAN) with aqueous ammonium sulfate solutions of different concentration as mobile phases. It was found that increasing the concentration of the salt in the mobile phase led to increased R-M values for all the substances. Linear relationships were established between salt concentration and R-M values and regression data of the plots obtained were used to determine the lipophilicity R-M(0) and C-0. Lipophilicity determined in this way was correlated with calculated log P values. For comparison of these results with chromatographic behavior in conventional RP TLC, the examined substances were subjected to thin-layer chromatography on RP-18 silica gel with methanol-water mobile phases.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography - Modern TLC
T1  - Examination of the hydrophobicity of ACE inhibitors and their active metabolites by salting-out thin-layer chromatography
VL  - 18
IS  - 102
SP  - 98
EP  - 103
DO  - 10.1556/JPC.18.2005.2.2
ER  - 
@article{
author = "Odović, Jadranka and Stojimirović, Biljana and Aleksić, Mirjana and Milojković-Opsenica, Dušanka and Tešić, Živoslav",
year = "2005",
abstract = "The behavior of five ACE inhibitors and their active degradation products in salting-out thin-layer chromatography (SO TLC) has been examined on silica gel, cellulose, and polyacrylonitrile (PAN) with aqueous ammonium sulfate solutions of different concentration as mobile phases. It was found that increasing the concentration of the salt in the mobile phase led to increased R-M values for all the substances. Linear relationships were established between salt concentration and R-M values and regression data of the plots obtained were used to determine the lipophilicity R-M(0) and C-0. Lipophilicity determined in this way was correlated with calculated log P values. For comparison of these results with chromatographic behavior in conventional RP TLC, the examined substances were subjected to thin-layer chromatography on RP-18 silica gel with methanol-water mobile phases.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Examination of the hydrophobicity of ACE inhibitors and their active metabolites by salting-out thin-layer chromatography",
volume = "18",
number = "102",
pages = "98-103",
doi = "10.1556/JPC.18.2005.2.2"
}
Odović, J., Stojimirović, B., Aleksić, M., Milojković-Opsenica, D.,& Tešić, Ž.. (2005). Examination of the hydrophobicity of ACE inhibitors and their active metabolites by salting-out thin-layer chromatography. in Journal of Planar Chromatography - Modern TLC
Research Inst Medicinal Plants, Budakalasz., 18(102), 98-103.
https://doi.org/10.1556/JPC.18.2005.2.2
Odović J, Stojimirović B, Aleksić M, Milojković-Opsenica D, Tešić Ž. Examination of the hydrophobicity of ACE inhibitors and their active metabolites by salting-out thin-layer chromatography. in Journal of Planar Chromatography - Modern TLC. 2005;18(102):98-103.
doi:10.1556/JPC.18.2005.2.2 .
Odović, Jadranka, Stojimirović, Biljana, Aleksić, Mirjana, Milojković-Opsenica, Dušanka, Tešić, Živoslav, "Examination of the hydrophobicity of ACE inhibitors and their active metabolites by salting-out thin-layer chromatography" in Journal of Planar Chromatography - Modern TLC, 18, no. 102 (2005):98-103,
https://doi.org/10.1556/JPC.18.2005.2.2 . .
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