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Reactive organoallyl species generated from aryl halides and allene: allylation of alpha,beta-unsaturated aldehydes and cyclic ketones employing Pd/In transmetallation processes

Cleghorn, Laura A. T.; Grigg, Ronald; Savić, Vladimir; Simić, Milena

(Pergamon-Elsevier Science Ltd, Oxford, 2008)

TY  - JOUR
AU  - Cleghorn, Laura A. T.
AU  - Grigg, Ronald
AU  - Savić, Vladimir
AU  - Simić, Milena
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1122
AB  - Allylation of alpha,beta-unsaturated aldehydes and cyclic ketones promoted by Pd/In transmetallation processes has been Studied. The unsaturated aldehydes underwent regioselective 1,2-addition to afford secondary homoally alcohols. The reactions have been performed using Pd(OAc)(2)/PPh(3) as catalytic system and metallic indium affording the products in good yields. The same transformation with unsaturated ketones proved to be less efficient, while saturated cyclic ketones delivered generally excellent yields in the presence of Cul. In these latter processes the presence of a distal heteroatom influences the reaction rate.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Tetrahedron Letters
T1  - Reactive organoallyl species generated from aryl halides and allene: allylation of alpha,beta-unsaturated aldehydes and cyclic ketones employing Pd/In transmetallation processes
VL  - 64
IS  - 37
SP  - 8731
EP  - 8737
DO  - 10.1016/j.tet.2008.06.100
ER  - 
@article{
author = "Cleghorn, Laura A. T. and Grigg, Ronald and Savić, Vladimir and Simić, Milena",
year = "2008",
abstract = "Allylation of alpha,beta-unsaturated aldehydes and cyclic ketones promoted by Pd/In transmetallation processes has been Studied. The unsaturated aldehydes underwent regioselective 1,2-addition to afford secondary homoally alcohols. The reactions have been performed using Pd(OAc)(2)/PPh(3) as catalytic system and metallic indium affording the products in good yields. The same transformation with unsaturated ketones proved to be less efficient, while saturated cyclic ketones delivered generally excellent yields in the presence of Cul. In these latter processes the presence of a distal heteroatom influences the reaction rate.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Tetrahedron Letters",
title = "Reactive organoallyl species generated from aryl halides and allene: allylation of alpha,beta-unsaturated aldehydes and cyclic ketones employing Pd/In transmetallation processes",
volume = "64",
number = "37",
pages = "8731-8737",
doi = "10.1016/j.tet.2008.06.100"
}
Cleghorn, L. A. T., Grigg, R., Savić, V.,& Simić, M.. (2008). Reactive organoallyl species generated from aryl halides and allene: allylation of alpha,beta-unsaturated aldehydes and cyclic ketones employing Pd/In transmetallation processes. in Tetrahedron Letters
Pergamon-Elsevier Science Ltd, Oxford., 64(37), 8731-8737.
https://doi.org/10.1016/j.tet.2008.06.100
Cleghorn LAT, Grigg R, Savić V, Simić M. Reactive organoallyl species generated from aryl halides and allene: allylation of alpha,beta-unsaturated aldehydes and cyclic ketones employing Pd/In transmetallation processes. in Tetrahedron Letters. 2008;64(37):8731-8737.
doi:10.1016/j.tet.2008.06.100 .
Cleghorn, Laura A. T., Grigg, Ronald, Savić, Vladimir, Simić, Milena, "Reactive organoallyl species generated from aryl halides and allene: allylation of alpha,beta-unsaturated aldehydes and cyclic ketones employing Pd/In transmetallation processes" in Tetrahedron Letters, 64, no. 37 (2008):8731-8737,
https://doi.org/10.1016/j.tet.2008.06.100 . .
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Stereoselective synthesis of chiral beta(2,3)-disubstituted-beta-amino acid derivatives using Pd/In transmetallation cascade processes

Grigg, Ronald; Blacker, John; Kilner, Colin; McCaffrey, Shaun; Savić, Vladimir; Sridharan, Visuvanathar

(Pergamon-Elsevier Science Ltd, Oxford, 2008)

TY  - JOUR
AU  - Grigg, Ronald
AU  - Blacker, John
AU  - Kilner, Colin
AU  - McCaffrey, Shaun
AU  - Savić, Vladimir
AU  - Sridharan, Visuvanathar
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1115
AB  - A new, highly efficient synthesis of chiral beta(2.3)-disubstituted-beta-amino acid derivatives has been developed, based on an allylation procedure employing allene and a catalytic Pd/In bimetallic process.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Tetrahedron Letters
T1  - Stereoselective synthesis of chiral beta(2,3)-disubstituted-beta-amino acid derivatives using Pd/In transmetallation cascade processes
VL  - 64
IS  - 35
SP  - 8177
EP  - 8181
DO  - 10.1016/j.tet.2008.06.037
ER  - 
@article{
author = "Grigg, Ronald and Blacker, John and Kilner, Colin and McCaffrey, Shaun and Savić, Vladimir and Sridharan, Visuvanathar",
year = "2008",
abstract = "A new, highly efficient synthesis of chiral beta(2.3)-disubstituted-beta-amino acid derivatives has been developed, based on an allylation procedure employing allene and a catalytic Pd/In bimetallic process.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Tetrahedron Letters",
title = "Stereoselective synthesis of chiral beta(2,3)-disubstituted-beta-amino acid derivatives using Pd/In transmetallation cascade processes",
volume = "64",
number = "35",
pages = "8177-8181",
doi = "10.1016/j.tet.2008.06.037"
}
Grigg, R., Blacker, J., Kilner, C., McCaffrey, S., Savić, V.,& Sridharan, V.. (2008). Stereoselective synthesis of chiral beta(2,3)-disubstituted-beta-amino acid derivatives using Pd/In transmetallation cascade processes. in Tetrahedron Letters
Pergamon-Elsevier Science Ltd, Oxford., 64(35), 8177-8181.
https://doi.org/10.1016/j.tet.2008.06.037
Grigg R, Blacker J, Kilner C, McCaffrey S, Savić V, Sridharan V. Stereoselective synthesis of chiral beta(2,3)-disubstituted-beta-amino acid derivatives using Pd/In transmetallation cascade processes. in Tetrahedron Letters. 2008;64(35):8177-8181.
doi:10.1016/j.tet.2008.06.037 .
Grigg, Ronald, Blacker, John, Kilner, Colin, McCaffrey, Shaun, Savić, Vladimir, Sridharan, Visuvanathar, "Stereoselective synthesis of chiral beta(2,3)-disubstituted-beta-amino acid derivatives using Pd/In transmetallation cascade processes" in Tetrahedron Letters, 64, no. 35 (2008):8177-8181,
https://doi.org/10.1016/j.tet.2008.06.037 . .
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