TY  - JOUR
AU  - Lupattelli, Angela
AU  - Twigg, Michael J.
AU  - Zagorodnikova, Ksenia
AU  - Moretti, Myla E.
AU  - Drozd, Mariola
AU  - Panchaud, Alice
AU  - Rieutord, Andre
AU  - Juraski, Romana Gjergja
AU  - Odalović, Marina
AU  - Kennedy, Debra
AU  - Rudolf, Gorazd
AU  - Juch, Herbert
AU  - Nordeng, Hedvig
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3227
AB  - Purpose: This study aimed at exploring the prevalence of self-reported antenatal and postnatal depressive symptoms by severity across multiple countries and the association between antidepressant treatment in pregnancy and postnatal symptom severity. Materials and methods: This was a multinational web-based study conducted across 12 European countries (n=8069). Uniform data collection was ensured via an electronic questionnaire. Pregnant women at any gestational week and mothers of children with  lt 1 year of age could participate. We used the Edinburgh Postnatal Depression Scale (EPDS) to measure the prevalence of antenatal and postnatal depressive symptoms according to severity, which were corrected by survey weight adjustment (descriptive analysis). Within mothers with a psychiatric disorder (n=173), we estimated the association between antidepressant treatment in pregnancy and postnatal depressive symptom severity, as standardized EPDS mean scores, via the inverse probability of treatment weight (association analysis). Results: In the descriptive analysis (n=8069), the period prevalence of moderate-to-very severe depressive symptoms was higher in the western and eastern regions relative to the northern region, both in the antenatal period (6.8%-7.5% vs 4.3%) and in the postnatal period (7.6% vs 4.7%). One in two mothers with psychiatric disorders used an antidepressant in pregnancy (86 of 173). In the association analysis, women medicated at any time during pregnancy (adjusted beta=-0.34, 95% confidence interval [CI] =-0.66, -0.02) had a significant postnatal symptom severity reduction compared with the nonmedicated counterpart. This effect was larger (beta=-0.74, 95% CI =-1.24, -0.24) when the analysis was restricted to mothers within 6 months after childbirth. Conclusion: The prevalence of self-reported antenatal and postnatal depressive symptoms differs across European countries. Among women with psychiatric disorders, those who had been on treatment with antidepressants during pregnancy were less likely to report postnatal depressive symptoms, particularly within the 6-month period after childbirth, compared with the nonmedicated counterpart.
PB  - Dove Medical Press Ltd, Albany
T2  - Clinical Epidemiology
T1  - Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale
VL  - 10
SP  - 655
EP  - 669
DO  - 10.2147/CLEP.S156210
ER  - 

@article{
author = "Lupattelli, Angela and Twigg, Michael J. and Zagorodnikova, Ksenia and Moretti, Myla E. and Drozd, Mariola and Panchaud, Alice and Rieutord, Andre and Juraski, Romana Gjergja and Odalović, Marina and Kennedy, Debra and Rudolf, Gorazd and Juch, Herbert and Nordeng, Hedvig",
year = "2018",
abstract = "Purpose: This study aimed at exploring the prevalence of self-reported antenatal and postnatal depressive symptoms by severity across multiple countries and the association between antidepressant treatment in pregnancy and postnatal symptom severity. Materials and methods: This was a multinational web-based study conducted across 12 European countries (n=8069). Uniform data collection was ensured via an electronic questionnaire. Pregnant women at any gestational week and mothers of children with  lt 1 year of age could participate. We used the Edinburgh Postnatal Depression Scale (EPDS) to measure the prevalence of antenatal and postnatal depressive symptoms according to severity, which were corrected by survey weight adjustment (descriptive analysis). Within mothers with a psychiatric disorder (n=173), we estimated the association between antidepressant treatment in pregnancy and postnatal depressive symptom severity, as standardized EPDS mean scores, via the inverse probability of treatment weight (association analysis). Results: In the descriptive analysis (n=8069), the period prevalence of moderate-to-very severe depressive symptoms was higher in the western and eastern regions relative to the northern region, both in the antenatal period (6.8%-7.5% vs 4.3%) and in the postnatal period (7.6% vs 4.7%). One in two mothers with psychiatric disorders used an antidepressant in pregnancy (86 of 173). In the association analysis, women medicated at any time during pregnancy (adjusted beta=-0.34, 95% confidence interval [CI] =-0.66, -0.02) had a significant postnatal symptom severity reduction compared with the nonmedicated counterpart. This effect was larger (beta=-0.74, 95% CI =-1.24, -0.24) when the analysis was restricted to mothers within 6 months after childbirth. Conclusion: The prevalence of self-reported antenatal and postnatal depressive symptoms differs across European countries. Among women with psychiatric disorders, those who had been on treatment with antidepressants during pregnancy were less likely to report postnatal depressive symptoms, particularly within the 6-month period after childbirth, compared with the nonmedicated counterpart.",
publisher = "Dove Medical Press Ltd, Albany",
journal = "Clinical Epidemiology",
title = "Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale",
volume = "10",
pages = "655-669",
doi = "10.2147/CLEP.S156210"
}

Lupattelli, A., Twigg, M. J., Zagorodnikova, K., Moretti, M. E., Drozd, M., Panchaud, A., Rieutord, A., Juraski, R. G., Odalović, M., Kennedy, D., Rudolf, G., Juch, H.,& Nordeng, H.. (2018). Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale. in Clinical Epidemiology
Dove Medical Press Ltd, Albany., 10, 655-669.
https://doi.org/10.2147/CLEP.S156210

Lupattelli A, Twigg MJ, Zagorodnikova K, Moretti ME, Drozd M, Panchaud A, Rieutord A, Juraski RG, Odalović M, Kennedy D, Rudolf G, Juch H, Nordeng H. Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale. in Clinical Epidemiology. 2018;10:655-669.
doi:10.2147/CLEP.S156210 .

Lupattelli, Angela, Twigg, Michael J., Zagorodnikova, Ksenia, Moretti, Myla E., Drozd, Mariola, Panchaud, Alice, Rieutord, Andre, Juraski, Romana Gjergja, Odalović, Marina, Kennedy, Debra, Rudolf, Gorazd, Juch, Herbert, Nordeng, Hedvig, "Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale" in Clinical Epidemiology, 10 (2018):655-669,
https://doi.org/10.2147/CLEP.S156210 . .

TY  - JOUR
AU  - Odalović, Marina
AU  - Milanković, Silje
AU  - Holst, Lone
AU  - Nordeng, Hedvig
AU  - Heitmann, Kristine
AU  - Tasić, Ljiljana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2694
AB  - Objectives: To describe, compare and evaluate whether pharmacists in two European countries, Serbia and Norway, give appropriate counselling for common ailments in pregnancy. Design: A cross sectional, web-based study. Participants and Settings: A study was conducted among Serbian and Norwegian pharmacists during two four-month study periods in 2012 respectively 2014. Participants were recruited through postal and electronic invitation facilitated by several pharmacy chains. Participation in the study was anonymous and voluntary. Measurement instrument: Pharmacists were presented with the questionnaire that included five scenarios (back pain, heavy legs, nausea, cold and constipation in pregnancy) and were asked to give their advice about use of medicines, supplements (e.g. herbal products, vitamins, minerals), non-pharmacological treatment and referral to physician in each condition. Findings: In total, 276 pharmacists, 119 in Serbia and 157 in Norway, accepted to participate in the study. Recommendation about medicines use ranged from 32% (heavy legs) to 71% (back pain) in Serbia and from 3% (heavy legs) to 92% (constipation) in Norway. Several pharmacists' recommendations on medicines and supplements use were inappropriate. Recommendation about non-pharmacological treatments ranged from 11% (nausea) to 50% (heavy legs) in Serbia and from 12% (constipation) to 63% (cold) in Norway. Approximately 12% of the Norwegian and Serbian pharmacists offered referral to a physician as only advice for nausea in pregnancy, indicating a lack of confidence in or knowledge about this common ailment in pregnancy. Key conclusions and implications for practice: Large differences in counselling of pregnant women by pharmacists in Serbia and Norway were observed. Enhancement of pharmacists' knowledge about treatment of common ailments in pregnancy is needed and will enhance pharmacists' role in improving maternal health.
PB  - Elsevier Sci Ltd, Oxford
T2  - Midwifery
T1  - Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway
VL  - 40
SP  - 79
EP  - 86
DO  - 10.1016/j.midw.2016.06.003
ER  - 

@article{
author = "Odalović, Marina and Milanković, Silje and Holst, Lone and Nordeng, Hedvig and Heitmann, Kristine and Tasić, Ljiljana",
year = "2016",
abstract = "Objectives: To describe, compare and evaluate whether pharmacists in two European countries, Serbia and Norway, give appropriate counselling for common ailments in pregnancy. Design: A cross sectional, web-based study. Participants and Settings: A study was conducted among Serbian and Norwegian pharmacists during two four-month study periods in 2012 respectively 2014. Participants were recruited through postal and electronic invitation facilitated by several pharmacy chains. Participation in the study was anonymous and voluntary. Measurement instrument: Pharmacists were presented with the questionnaire that included five scenarios (back pain, heavy legs, nausea, cold and constipation in pregnancy) and were asked to give their advice about use of medicines, supplements (e.g. herbal products, vitamins, minerals), non-pharmacological treatment and referral to physician in each condition. Findings: In total, 276 pharmacists, 119 in Serbia and 157 in Norway, accepted to participate in the study. Recommendation about medicines use ranged from 32% (heavy legs) to 71% (back pain) in Serbia and from 3% (heavy legs) to 92% (constipation) in Norway. Several pharmacists' recommendations on medicines and supplements use were inappropriate. Recommendation about non-pharmacological treatments ranged from 11% (nausea) to 50% (heavy legs) in Serbia and from 12% (constipation) to 63% (cold) in Norway. Approximately 12% of the Norwegian and Serbian pharmacists offered referral to a physician as only advice for nausea in pregnancy, indicating a lack of confidence in or knowledge about this common ailment in pregnancy. Key conclusions and implications for practice: Large differences in counselling of pregnant women by pharmacists in Serbia and Norway were observed. Enhancement of pharmacists' knowledge about treatment of common ailments in pregnancy is needed and will enhance pharmacists' role in improving maternal health.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Midwifery",
title = "Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway",
volume = "40",
pages = "79-86",
doi = "10.1016/j.midw.2016.06.003"
}

Odalović, M., Milanković, S., Holst, L., Nordeng, H., Heitmann, K.,& Tasić, L.. (2016). Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway. in Midwifery
Elsevier Sci Ltd, Oxford., 40, 79-86.
https://doi.org/10.1016/j.midw.2016.06.003

Odalović M, Milanković S, Holst L, Nordeng H, Heitmann K, Tasić L. Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway. in Midwifery. 2016;40:79-86.
doi:10.1016/j.midw.2016.06.003 .

Odalović, Marina, Milanković, Silje, Holst, Lone, Nordeng, Hedvig, Heitmann, Kristine, Tasić, Ljiljana, "Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway" in Midwifery, 40 (2016):79-86,
https://doi.org/10.1016/j.midw.2016.06.003 . .

TY  - JOUR
AU  - Lupattelli, Angela
AU  - Spigset, Olav
AU  - Twigg, Michael J.
AU  - Zagorodnikova, Ksenia
AU  - Mardby, Ann-Charlotte
AU  - Moretti, Myla E.
AU  - Drozd, Mariola
AU  - Panchaud, Alice
AU  - Haemeen-Anttila, Katri
AU  - Rieutord, Andre
AU  - Juraski, R. Gjergja
AU  - Odalović, Marina
AU  - Kennedy, Debra
AU  - Rudolf, Gorazd
AU  - Juch, Herbert
AU  - Passier, Anneke
AU  - Bjoernsdottir, Ingunn
AU  - Nordeng, Hedvig
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2154
AB  - Objectives Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with medications use in pregnancy from a multinational perspective, with emphasis on type of medication utilised and indication for use. Design Cross-sectional, web-based study performed within the period from 1 October 2011 to 29 February 2012. Uniform collection of drug utilisation data was performed via an anonymous online questionnaire. Setting Multinational study in Europe (Western, Northern and Eastern), North and South America and Australia. Participants Pregnant women and new mothers with children less than 1year of age. Primary and secondary outcome measures Prevalence of and factors associated with medication use for acute/short-term illnesses, chronic/long-term disorders and over-the-counter (OTC) medication use. Results The study population included 9459 women, of which 81.2% reported use of at least one medication (prescribed or OTC) during pregnancy. Overall, OTC medication use occurred in 66.9% of the pregnancies, whereas 68.4% and 17% of women reported use of at least one medication for treatment of acute/short-term illnesses and chronic/long-term disorders, respectively. The extent of self-reported medicated illnesses and types of medication used by indication varied across regions, especially in relation to urinary tract infections, depression or OTC nasal sprays. Women with higher age or lower educational level, housewives or women with an unplanned pregnancy were those most often reporting use of medication for chronic/long-term disorders. Immigrant women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34 to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to 0.83) were less likely to report use of medication for chronic/long-term disorders during pregnancy than non-immigrants. Conclusions In this study, the majority of women in Europe, North America, South America and Australia used at least one medication during pregnancy. There was a substantial inter-region variability in the types of medication used.
PB  - BMJ PUBLISHING GROUP, LONDON
T2  - BMJ Open
T1  - Medication use in pregnancy: a cross-sectional, multinational web-based study
VL  - 4
IS  - 2
DO  - 10.1136/bmjopen-2013-004365
ER  - 

@article{
author = "Lupattelli, Angela and Spigset, Olav and Twigg, Michael J. and Zagorodnikova, Ksenia and Mardby, Ann-Charlotte and Moretti, Myla E. and Drozd, Mariola and Panchaud, Alice and Haemeen-Anttila, Katri and Rieutord, Andre and Juraski, R. Gjergja and Odalović, Marina and Kennedy, Debra and Rudolf, Gorazd and Juch, Herbert and Passier, Anneke and Bjoernsdottir, Ingunn and Nordeng, Hedvig",
year = "2014",
abstract = "Objectives Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with medications use in pregnancy from a multinational perspective, with emphasis on type of medication utilised and indication for use. Design Cross-sectional, web-based study performed within the period from 1 October 2011 to 29 February 2012. Uniform collection of drug utilisation data was performed via an anonymous online questionnaire. Setting Multinational study in Europe (Western, Northern and Eastern), North and South America and Australia. Participants Pregnant women and new mothers with children less than 1year of age. Primary and secondary outcome measures Prevalence of and factors associated with medication use for acute/short-term illnesses, chronic/long-term disorders and over-the-counter (OTC) medication use. Results The study population included 9459 women, of which 81.2% reported use of at least one medication (prescribed or OTC) during pregnancy. Overall, OTC medication use occurred in 66.9% of the pregnancies, whereas 68.4% and 17% of women reported use of at least one medication for treatment of acute/short-term illnesses and chronic/long-term disorders, respectively. The extent of self-reported medicated illnesses and types of medication used by indication varied across regions, especially in relation to urinary tract infections, depression or OTC nasal sprays. Women with higher age or lower educational level, housewives or women with an unplanned pregnancy were those most often reporting use of medication for chronic/long-term disorders. Immigrant women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34 to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to 0.83) were less likely to report use of medication for chronic/long-term disorders during pregnancy than non-immigrants. Conclusions In this study, the majority of women in Europe, North America, South America and Australia used at least one medication during pregnancy. There was a substantial inter-region variability in the types of medication used.",
publisher = "BMJ PUBLISHING GROUP, LONDON",
journal = "BMJ Open",
title = "Medication use in pregnancy: a cross-sectional, multinational web-based study",
volume = "4",
number = "2",
doi = "10.1136/bmjopen-2013-004365"
}

Lupattelli, A., Spigset, O., Twigg, M. J., Zagorodnikova, K., Mardby, A., Moretti, M. E., Drozd, M., Panchaud, A., Haemeen-Anttila, K., Rieutord, A., Juraski, R. G., Odalović, M., Kennedy, D., Rudolf, G., Juch, H., Passier, A., Bjoernsdottir, I.,& Nordeng, H.. (2014). Medication use in pregnancy: a cross-sectional, multinational web-based study. in BMJ Open
BMJ PUBLISHING GROUP, LONDON., 4(2).
https://doi.org/10.1136/bmjopen-2013-004365

Lupattelli A, Spigset O, Twigg MJ, Zagorodnikova K, Mardby A, Moretti ME, Drozd M, Panchaud A, Haemeen-Anttila K, Rieutord A, Juraski RG, Odalović M, Kennedy D, Rudolf G, Juch H, Passier A, Bjoernsdottir I, Nordeng H. Medication use in pregnancy: a cross-sectional, multinational web-based study. in BMJ Open. 2014;4(2).
doi:10.1136/bmjopen-2013-004365 .

Lupattelli, Angela, Spigset, Olav, Twigg, Michael J., Zagorodnikova, Ksenia, Mardby, Ann-Charlotte, Moretti, Myla E., Drozd, Mariola, Panchaud, Alice, Haemeen-Anttila, Katri, Rieutord, Andre, Juraski, R. Gjergja, Odalović, Marina, Kennedy, Debra, Rudolf, Gorazd, Juch, Herbert, Passier, Anneke, Bjoernsdottir, Ingunn, Nordeng, Hedvig, "Medication use in pregnancy: a cross-sectional, multinational web-based study" in BMJ Open, 4, no. 2 (2014),
https://doi.org/10.1136/bmjopen-2013-004365 . .