TY  - JOUR
AU  - Terzić, Dragana
AU  - Tadić, Ivana
AU  - Lakić, Dragana
AU  - Odalović, Marina
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4283
AB  - Healthcare  professionals  should  serve  as  promoters  of  ra-tional  antibiotic  use  in  attempt  to  decrease  antibiotics  misuse  within  the  process  of  self-medication. Current  pilot  study  was  undertaken  with  the  aim  to  identify  potential  predictors  of  self-medication with antibiotics (SMA) and to describe SMA practice among nursing students in Serbia. Data have been collected dur-ing  the  period  March-May,  2016  in  Medical  school  of  bachelor  degree, in Belgrade. Self-reported questionnaire served as a data source.  Descriptive  statistic  was  used  to  analyse  study  sample  characteristics.  Chi-square  test  was  used  to  test  differences  be-tween groups. Study sample have included 138 participants. Al-most half of them, 43.8%, practice SMA. Life style (smoking, al-cohol consumption, sleeping habits and physical activity) and so-cio-demographic  characteristics  (excepted  school  grade)  were  not  shown  as  SMA  determinants.  Time  &  money  savings  were  stated as the most frequent reason for SMA, while common cold, sore  throat  and  cough  were  the  most  common  conditions  cured  through SMA. Pharmacists’ recommendations and previous pos-itive experience were specified as the most important in the pro-cess of antibiotics selection, indicated by 50.0% and 37.5% par-ticipants,  respectively.  Amoxicillin  was  the  most  frequently  used  antibiotic in SMA, used by 50% of participants who practice SMA. High  proportion  of  SMA  and  observed  practice  among  nursing  students in Serbia call for efforts with regards to relevant educa-tion  about  rational  antibiotic  use,  actual  clinical  guidelines  and  potential consequences of misuse.
AB  - Zdravstveni  stručnjaci  bi  trebalo  da  služe  kao  pokretači  ra-cionalne  upotrebe  antibiotika  u  pokušaju  da  se  smanji  zloupo-treba  antibiotika  kroz  proces  samomedikacije.  Pilot  studija  je  sprovedena   sa   ciljem   da   se   utvrde   potencijalni   prediktori   samomedikacije  antibioticima  (SMA)  i  da  se  opiše  praksa  SMA  među studentima sestrinstva u Srbiji. Podaci su sakupljeni tokom perioda  Mart-Maj  2016,  u  Višoj  školi  strukovnih  studija  u  Be-ogradu,  Srbija.  Za  sakupljanje  podataka  korišćen  je  upitnih  za samo-popunjavanje.  U  analizi  karakteristika  ispitivanog  uzorka  korišćena je deskriptivna statistika. Hi-kvadrat test je korišćen za ispitivanje razlike između grupa. Ukupan broj učesnika u studiji bio je 138. Gotovo polovina, 43,8% je koristila SMA. Životni stil (pušenje,  konzumiranje  alkohola,  navike  u  pogledu  sna,  fizička aktivnost)   i   socio-demografske   karakteristike   (izuzev   godine   studija)  nisu  pokazane  kao  SMA.  Uštede  u  vremenu  i  novcu  su  navedene  kao  najčešći  razlog  za  SMA,  dok  su  prehlada,  upala grla  i  kašalj  najčešće  indikacije  tretirane  kroz  SMA.  Preporuke  farmaceuta  i  prethodno  pozitivno  iskustvo  su  navedeni  kao  najznačajniji faktori u odabiru antibiotika, što je tvrdilo 50,0% i 37,5% učesnika, redom. Amoksicilin je bio najčešće korišćen an-tibiotik koji je koristilo 50% učesnika kroz SMA. Visok procenat SMA  i  uočena  praksa  među  studentima  sestrinstva  u  Srbiji ukazuje na potrebe za relevantnom edukacijom u vezi sa racion-alnom  upotrebom  antibiotika,  aktuelnim  preporukama  u  klin-ičkim  vodičima  i  potencijalnim  posledicama  nepoštovanja  datih  preporuka.
PB  - University of Kragujevac, Faculty of Science
T2  - Serbian Journal of Experimental and Clinical Research
T1  - Self-medication with antibiotics among nursing students in Serbia: pilot study
T1  - Samomedikacija antibioticima među studentima sesrtinstva u Srbiji: pilot studija
VL  - 23
IS  - 3
SP  - 229
EP  - 235
DO  - 10.2478/sjecr-2019-0055
ER  - 

@article{
author = "Terzić, Dragana and Tadić, Ivana and Lakić, Dragana and Odalović, Marina",
year = "2022",
abstract = "Healthcare  professionals  should  serve  as  promoters  of  ra-tional  antibiotic  use  in  attempt  to  decrease  antibiotics  misuse  within  the  process  of  self-medication. Current  pilot  study  was  undertaken  with  the  aim  to  identify  potential  predictors  of  self-medication with antibiotics (SMA) and to describe SMA practice among nursing students in Serbia. Data have been collected dur-ing  the  period  March-May,  2016  in  Medical  school  of  bachelor  degree, in Belgrade. Self-reported questionnaire served as a data source.  Descriptive  statistic  was  used  to  analyse  study  sample  characteristics.  Chi-square  test  was  used  to  test  differences  be-tween groups. Study sample have included 138 participants. Al-most half of them, 43.8%, practice SMA. Life style (smoking, al-cohol consumption, sleeping habits and physical activity) and so-cio-demographic  characteristics  (excepted  school  grade)  were  not  shown  as  SMA  determinants.  Time  &  money  savings  were  stated as the most frequent reason for SMA, while common cold, sore  throat  and  cough  were  the  most  common  conditions  cured  through SMA. Pharmacists’ recommendations and previous pos-itive experience were specified as the most important in the pro-cess of antibiotics selection, indicated by 50.0% and 37.5% par-ticipants,  respectively.  Amoxicillin  was  the  most  frequently  used  antibiotic in SMA, used by 50% of participants who practice SMA. High  proportion  of  SMA  and  observed  practice  among  nursing  students in Serbia call for efforts with regards to relevant educa-tion  about  rational  antibiotic  use,  actual  clinical  guidelines  and  potential consequences of misuse., Zdravstveni  stručnjaci  bi  trebalo  da  služe  kao  pokretači  ra-cionalne  upotrebe  antibiotika  u  pokušaju  da  se  smanji  zloupo-treba  antibiotika  kroz  proces  samomedikacije.  Pilot  studija  je  sprovedena   sa   ciljem   da   se   utvrde   potencijalni   prediktori   samomedikacije  antibioticima  (SMA)  i  da  se  opiše  praksa  SMA  među studentima sestrinstva u Srbiji. Podaci su sakupljeni tokom perioda  Mart-Maj  2016,  u  Višoj  školi  strukovnih  studija  u  Be-ogradu,  Srbija.  Za  sakupljanje  podataka  korišćen  je  upitnih  za samo-popunjavanje.  U  analizi  karakteristika  ispitivanog  uzorka  korišćena je deskriptivna statistika. Hi-kvadrat test je korišćen za ispitivanje razlike između grupa. Ukupan broj učesnika u studiji bio je 138. Gotovo polovina, 43,8% je koristila SMA. Životni stil (pušenje,  konzumiranje  alkohola,  navike  u  pogledu  sna,  fizička aktivnost)   i   socio-demografske   karakteristike   (izuzev   godine   studija)  nisu  pokazane  kao  SMA.  Uštede  u  vremenu  i  novcu  su  navedene  kao  najčešći  razlog  za  SMA,  dok  su  prehlada,  upala grla  i  kašalj  najčešće  indikacije  tretirane  kroz  SMA.  Preporuke  farmaceuta  i  prethodno  pozitivno  iskustvo  su  navedeni  kao  najznačajniji faktori u odabiru antibiotika, što je tvrdilo 50,0% i 37,5% učesnika, redom. Amoksicilin je bio najčešće korišćen an-tibiotik koji je koristilo 50% učesnika kroz SMA. Visok procenat SMA  i  uočena  praksa  među  studentima  sestrinstva  u  Srbiji ukazuje na potrebe za relevantnom edukacijom u vezi sa racion-alnom  upotrebom  antibiotika,  aktuelnim  preporukama  u  klin-ičkim  vodičima  i  potencijalnim  posledicama  nepoštovanja  datih  preporuka.",
publisher = "University of Kragujevac, Faculty of Science",
journal = "Serbian Journal of Experimental and Clinical Research",
title = "Self-medication with antibiotics among nursing students in Serbia: pilot study, Samomedikacija antibioticima među studentima sesrtinstva u Srbiji: pilot studija",
volume = "23",
number = "3",
pages = "229-235",
doi = "10.2478/sjecr-2019-0055"
}

Terzić, D., Tadić, I., Lakić, D.,& Odalović, M.. (2022). Self-medication with antibiotics among nursing students in Serbia: pilot study. in Serbian Journal of Experimental and Clinical Research
University of Kragujevac, Faculty of Science., 23(3), 229-235.
https://doi.org/10.2478/sjecr-2019-0055

Terzić D, Tadić I, Lakić D, Odalović M. Self-medication with antibiotics among nursing students in Serbia: pilot study. in Serbian Journal of Experimental and Clinical Research. 2022;23(3):229-235.
doi:10.2478/sjecr-2019-0055 .

Terzić, Dragana, Tadić, Ivana, Lakić, Dragana, Odalović, Marina, "Self-medication with antibiotics among nursing students in Serbia: pilot study" in Serbian Journal of Experimental and Clinical Research, 23, no. 3 (2022):229-235,
https://doi.org/10.2478/sjecr-2019-0055 . .

TY  - JOUR
AU  - Lakić, Dragana
AU  - Travica, Jovana
AU  - Odalović, Marina
AU  - Tadić, Ivana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3030
AB  - Venous thromboembolism, including pulmonary embolism and deep vein thrombosis, is a signifi cant factor in morbidity and mortality of patients. New oral anticoagulants, such as apixaban, dabigatran, and rivaroxaban, have recently demonstrated their safety and efficacy in patients undergoing major orthopaedic surgery. Selection of the appropriate drug should be adjusted according to patient needs. Major bleeding is rare with new oral anticoagulants and is comparable with the bleeding rate associated with low-molecular-weight heparins. Clinical data indicate that therapy with apixaban and rivaroxaban was more effective compared to enoxaparin, while dabigatran has a similar efficacy to enoxaparin. Cost-effectiveness studies of new oral anticoagulants showed that these medicines offer higher efficacy with acceptable costs for the healthcare system, even saving costs in certain cases. Clinical practice in Serbia reflects considerably more frequent use of traditional anticoagulant medication therapy compared to new oral anticoagulants.
AB  - Venska tromboembolija, koja uključuje plućnu emboliju i duboku vensku trombozu, predstavlja značajan faktor morbiditeta i mortaliteta pacijenata. Novi oralni antikoagulansi, poput apiksabana, dabigatrana i rivaroksabana, su nedavno pokazali svoju bezbednost i efikasnost kod pacijenata koji se podvrgavaju velikim ortopedskim intervencijama. Izbor odgovarajućeg leka treba prilagoditi individualnim potrebama pacijenta. Velika krvarenja su relativno retka u toku primene novih oralnih antikoagulanasa i uporedivi su sa stopom krvarenja prilikom primene nisko-molekularnih heparina. Klinički podaci ukazuju da je terapija apiksabanom i rivarokabanom efikasnija u odnosu na enoksaparin, dok dabigatran ima slične efekte kao enoksaparin. Troškovna isplativost novih oralnih antikoagulanasa potvrđuje veću efikasnost sa prihvatljivim troškovima za zdravstveni sistem, u nekim slučajevima čak i sa uštedama.
PB  - Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac
T2  - Serbian Journal of Experimental and Clinical Research
T1  - Clinical and economic outcomes of new oral anticoagulants in orthopaedics
T1  - Klinički i ekonomski ishodi primene novih oralnih antikoagulanasa u ortopediji
VL  - 19
IS  - 1
SP  - 3
EP  - 9
DO  - 10.1515/SJECR-2017-0066
ER  - 

@article{
author = "Lakić, Dragana and Travica, Jovana and Odalović, Marina and Tadić, Ivana",
year = "2018",
abstract = "Venous thromboembolism, including pulmonary embolism and deep vein thrombosis, is a signifi cant factor in morbidity and mortality of patients. New oral anticoagulants, such as apixaban, dabigatran, and rivaroxaban, have recently demonstrated their safety and efficacy in patients undergoing major orthopaedic surgery. Selection of the appropriate drug should be adjusted according to patient needs. Major bleeding is rare with new oral anticoagulants and is comparable with the bleeding rate associated with low-molecular-weight heparins. Clinical data indicate that therapy with apixaban and rivaroxaban was more effective compared to enoxaparin, while dabigatran has a similar efficacy to enoxaparin. Cost-effectiveness studies of new oral anticoagulants showed that these medicines offer higher efficacy with acceptable costs for the healthcare system, even saving costs in certain cases. Clinical practice in Serbia reflects considerably more frequent use of traditional anticoagulant medication therapy compared to new oral anticoagulants., Venska tromboembolija, koja uključuje plućnu emboliju i duboku vensku trombozu, predstavlja značajan faktor morbiditeta i mortaliteta pacijenata. Novi oralni antikoagulansi, poput apiksabana, dabigatrana i rivaroksabana, su nedavno pokazali svoju bezbednost i efikasnost kod pacijenata koji se podvrgavaju velikim ortopedskim intervencijama. Izbor odgovarajućeg leka treba prilagoditi individualnim potrebama pacijenta. Velika krvarenja su relativno retka u toku primene novih oralnih antikoagulanasa i uporedivi su sa stopom krvarenja prilikom primene nisko-molekularnih heparina. Klinički podaci ukazuju da je terapija apiksabanom i rivarokabanom efikasnija u odnosu na enoksaparin, dok dabigatran ima slične efekte kao enoksaparin. Troškovna isplativost novih oralnih antikoagulanasa potvrđuje veću efikasnost sa prihvatljivim troškovima za zdravstveni sistem, u nekim slučajevima čak i sa uštedama.",
publisher = "Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac",
journal = "Serbian Journal of Experimental and Clinical Research",
title = "Clinical and economic outcomes of new oral anticoagulants in orthopaedics, Klinički i ekonomski ishodi primene novih oralnih antikoagulanasa u ortopediji",
volume = "19",
number = "1",
pages = "3-9",
doi = "10.1515/SJECR-2017-0066"
}

Lakić, D., Travica, J., Odalović, M.,& Tadić, I.. (2018). Clinical and economic outcomes of new oral anticoagulants in orthopaedics. in Serbian Journal of Experimental and Clinical Research
Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac., 19(1), 3-9.
https://doi.org/10.1515/SJECR-2017-0066

Lakić D, Travica J, Odalović M, Tadić I. Clinical and economic outcomes of new oral anticoagulants in orthopaedics. in Serbian Journal of Experimental and Clinical Research. 2018;19(1):3-9.
doi:10.1515/SJECR-2017-0066 .

Lakić, Dragana, Travica, Jovana, Odalović, Marina, Tadić, Ivana, "Clinical and economic outcomes of new oral anticoagulants in orthopaedics" in Serbian Journal of Experimental and Clinical Research, 19, no. 1 (2018):3-9,
https://doi.org/10.1515/SJECR-2017-0066 . .

TY  - JOUR
AU  - Golić-Jelić, Ana
AU  - Tasić, Ljiljana
AU  - Krajnović, Dušanka
AU  - Odalović, Marina
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2897
AB  - The importance of preceptorship programs, for pharmacists and other health professionals, in order to develop careers and increase satisfaction at the work was recognized more than 30 years ago, while percepting is associated with positive personal and professional outcomes. The aim of this review was systematic review of the development and evaluation of preceptorship programs for pharmacist and identifying challenges and problems for preceptors. An electronic database PubMed was searched (last searched December 11, 2016). A total of 124 reports were found, and only 5 of them met our inclusion criteria. All of them assessed the development and evaluation of preceptorship programs, and also, helped us to identify challenges and problems. Assessed quality of two studies was high, two were assessed as moderate, and one study had low quality. Most studies showed an increase in mentors and interns confidence and job satisfaction and improved skills in critical thinking and problem solving after completing a preceptorship program. More original research is needed, and a small number of publication in this field is a confirmation by itself.
AB  - Značaj mentorskih programa u cilju razvoja karijere i povećanja zadovoljstva na poslu farmaceuta i drugih zdravstvenih radnika je prepoznat prije više od 30 godina, dok je mentorstvo povezano sa nizom pozitivnih ličnih i profesionalnih ishoda. Cilj ovog rada je bio sistematski pregled literature koji se odnosi na razvoj i evaluaciju programa profesionalnog usavršavanja mentora stručne prakse farmaceuta, kao i identifikacija najčešćih izazova i problema. Pretražena je elektronska baza naučnih radova PubMed (posljednji put 11. decembra 2016. godine). Od početno pronađena 124 rada samo je 5 zadovoljilo kriterijume za uključivanje u pregled. Studije koje su uključene treba da daju odgovore na ciljeve našeg sistematskog pregleda, da sagledaju razvoj i evaluaciju programa profesionalnog usavršavanja mentora stručne prakse farmaceuta, a ujedno i identifikuju izazove i probleme. Dvije studije su procjenjene kao visoko kvalitetne, dvije kao umjereno i jedna kao studija slabog kvaliteta. U većini studija rezultati pokazuju povećanje samopouzdanja i mentora i stažista nakon završenog programa za mentore, zatim povećanje zadovoljstva na poslu, te poboljšanje vještina u kritičkom razmišljanju i rješavanju problema. Mali broj radova koji se bave ovom temom upravo potvrđuje da su potrebna dodatna originalna istraživanja iz ove oblasti.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Professional development for pharmacy preceptors: Challenges and problems
T1  - Profesionalni razvoj mentora stručne prakse farmaceuta - izazovi i problem
VL  - 67
IS  - 3
SP  - 180
EP  - 195
DO  - 10.5937/arhfarm1703180G
ER  - 

@article{
author = "Golić-Jelić, Ana and Tasić, Ljiljana and Krajnović, Dušanka and Odalović, Marina",
year = "2017",
abstract = "The importance of preceptorship programs, for pharmacists and other health professionals, in order to develop careers and increase satisfaction at the work was recognized more than 30 years ago, while percepting is associated with positive personal and professional outcomes. The aim of this review was systematic review of the development and evaluation of preceptorship programs for pharmacist and identifying challenges and problems for preceptors. An electronic database PubMed was searched (last searched December 11, 2016). A total of 124 reports were found, and only 5 of them met our inclusion criteria. All of them assessed the development and evaluation of preceptorship programs, and also, helped us to identify challenges and problems. Assessed quality of two studies was high, two were assessed as moderate, and one study had low quality. Most studies showed an increase in mentors and interns confidence and job satisfaction and improved skills in critical thinking and problem solving after completing a preceptorship program. More original research is needed, and a small number of publication in this field is a confirmation by itself., Značaj mentorskih programa u cilju razvoja karijere i povećanja zadovoljstva na poslu farmaceuta i drugih zdravstvenih radnika je prepoznat prije više od 30 godina, dok je mentorstvo povezano sa nizom pozitivnih ličnih i profesionalnih ishoda. Cilj ovog rada je bio sistematski pregled literature koji se odnosi na razvoj i evaluaciju programa profesionalnog usavršavanja mentora stručne prakse farmaceuta, kao i identifikacija najčešćih izazova i problema. Pretražena je elektronska baza naučnih radova PubMed (posljednji put 11. decembra 2016. godine). Od početno pronađena 124 rada samo je 5 zadovoljilo kriterijume za uključivanje u pregled. Studije koje su uključene treba da daju odgovore na ciljeve našeg sistematskog pregleda, da sagledaju razvoj i evaluaciju programa profesionalnog usavršavanja mentora stručne prakse farmaceuta, a ujedno i identifikuju izazove i probleme. Dvije studije su procjenjene kao visoko kvalitetne, dvije kao umjereno i jedna kao studija slabog kvaliteta. U većini studija rezultati pokazuju povećanje samopouzdanja i mentora i stažista nakon završenog programa za mentore, zatim povećanje zadovoljstva na poslu, te poboljšanje vještina u kritičkom razmišljanju i rješavanju problema. Mali broj radova koji se bave ovom temom upravo potvrđuje da su potrebna dodatna originalna istraživanja iz ove oblasti.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Professional development for pharmacy preceptors: Challenges and problems, Profesionalni razvoj mentora stručne prakse farmaceuta - izazovi i problem",
volume = "67",
number = "3",
pages = "180-195",
doi = "10.5937/arhfarm1703180G"
}

Golić-Jelić, A., Tasić, L., Krajnović, D.,& Odalović, M.. (2017). Professional development for pharmacy preceptors: Challenges and problems. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 67(3), 180-195.
https://doi.org/10.5937/arhfarm1703180G

Golić-Jelić A, Tasić L, Krajnović D, Odalović M. Professional development for pharmacy preceptors: Challenges and problems. in Arhiv za farmaciju. 2017;67(3):180-195.
doi:10.5937/arhfarm1703180G .

Golić-Jelić, Ana, Tasić, Ljiljana, Krajnović, Dušanka, Odalović, Marina, "Professional development for pharmacy preceptors: Challenges and problems" in Arhiv za farmaciju, 67, no. 3 (2017):180-195,
https://doi.org/10.5937/arhfarm1703180G . .

TY  - JOUR
AU  - Tasić, Ljiljana
AU  - Kocić-Pešić, Vukica
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2539
AB  - Prevention of Type 2 diabetes (T2D) is clinical service useful to implement on community pharmacy settings (CP). The objectives of study were: to determine the risk factors for T2D in adults visiting a community pharmacy; to determine and describe component of pharmacists' interventions (PI) focusing on feasibility of complex intervention (CI). A cross-sectional study design and conducted (January 2010 to June 2011) on 20 CP in Serbia. Adult population was enrolled (304 patients). The pharmacist trained for implementation of complex PI (screening and counseling session). The national Questionnaire for T2D risk estimation was used for screening and Intervention check list was design and used for process of counseling. The DEPICT (Descriptive Elements of Pharmacist Intervention Characterization Tool) was used to describe the component of CI. High and very high risk score was estimated in age group 45-54 (10.80%) forward in age group 55-64 (9.60%); into the cohort below 45 year the 59 adults has low T2D risk score. The average value of PI/per patients was 4.02. From the eight domain/component (operational descriptor in DEPICT) the main component are 'education and counseling' with four type (items) of intervention performed in counseling session. As a conclusion, the pharmacists in CP detected and scoring risk of T2D in Serbian adults' population. The number and type of PI in counseling session adequate to participants clinical profile. Feasibility of the CI within the CP in Serbia was proved. For the outcomes measurements and impact of PI, a proper endpoint and follow-up study design should be conduct.
PB  - Assoc Pharmaceutical Teachers India, Bangalore
T2  - Indian Journal of Pharmaceutical Education and Research
T1  - Identification of Risk Factors for Diabetes Type 2 and Components of Pharmacists' Interventions in Community Pharmacy Setting: A Serbian Pilot Study
VL  - 50
IS  - 1
SP  - 90
EP  - 102
DO  - 10.5530/ijper.50.1.12
ER  - 

@article{
author = "Tasić, Ljiljana and Kocić-Pešić, Vukica",
year = "2016",
abstract = "Prevention of Type 2 diabetes (T2D) is clinical service useful to implement on community pharmacy settings (CP). The objectives of study were: to determine the risk factors for T2D in adults visiting a community pharmacy; to determine and describe component of pharmacists' interventions (PI) focusing on feasibility of complex intervention (CI). A cross-sectional study design and conducted (January 2010 to June 2011) on 20 CP in Serbia. Adult population was enrolled (304 patients). The pharmacist trained for implementation of complex PI (screening and counseling session). The national Questionnaire for T2D risk estimation was used for screening and Intervention check list was design and used for process of counseling. The DEPICT (Descriptive Elements of Pharmacist Intervention Characterization Tool) was used to describe the component of CI. High and very high risk score was estimated in age group 45-54 (10.80%) forward in age group 55-64 (9.60%); into the cohort below 45 year the 59 adults has low T2D risk score. The average value of PI/per patients was 4.02. From the eight domain/component (operational descriptor in DEPICT) the main component are 'education and counseling' with four type (items) of intervention performed in counseling session. As a conclusion, the pharmacists in CP detected and scoring risk of T2D in Serbian adults' population. The number and type of PI in counseling session adequate to participants clinical profile. Feasibility of the CI within the CP in Serbia was proved. For the outcomes measurements and impact of PI, a proper endpoint and follow-up study design should be conduct.",
publisher = "Assoc Pharmaceutical Teachers India, Bangalore",
journal = "Indian Journal of Pharmaceutical Education and Research",
title = "Identification of Risk Factors for Diabetes Type 2 and Components of Pharmacists' Interventions in Community Pharmacy Setting: A Serbian Pilot Study",
volume = "50",
number = "1",
pages = "90-102",
doi = "10.5530/ijper.50.1.12"
}

Tasić, L.,& Kocić-Pešić, V.. (2016). Identification of Risk Factors for Diabetes Type 2 and Components of Pharmacists' Interventions in Community Pharmacy Setting: A Serbian Pilot Study. in Indian Journal of Pharmaceutical Education and Research
Assoc Pharmaceutical Teachers India, Bangalore., 50(1), 90-102.
https://doi.org/10.5530/ijper.50.1.12

Tasić L, Kocić-Pešić V. Identification of Risk Factors for Diabetes Type 2 and Components of Pharmacists' Interventions in Community Pharmacy Setting: A Serbian Pilot Study. in Indian Journal of Pharmaceutical Education and Research. 2016;50(1):90-102.
doi:10.5530/ijper.50.1.12 .

Tasić, Ljiljana, Kocić-Pešić, Vukica, "Identification of Risk Factors for Diabetes Type 2 and Components of Pharmacists' Interventions in Community Pharmacy Setting: A Serbian Pilot Study" in Indian Journal of Pharmaceutical Education and Research, 50, no. 1 (2016):90-102,
https://doi.org/10.5530/ijper.50.1.12 . .

TY  - JOUR
AU  - Danić, Maja
AU  - Pavlović, Nebojša
AU  - Stanimirov, Bojan
AU  - Vukmirović, Sasa
AU  - Nikolić, Katarina
AU  - Agbaba, Danica
AU  - Mikov, Momir
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2610
AB  - Introduction: Distribution coefficient (D) is useful parameter for evaluating drugs permeability properties across biological membranes, which are of importance for drugs bioavailability. Given that bile acids are intensively studied as drug permeation-modifying and -solubilizing agents, the aim of this study was to estimate the influence of sodium salts of cholic (CA), deoxycholic (DCA) and 12-monoketocholic acids (MKC) on distribution coefficient of simvastatin (SV) (lactone [SVL] and acid form [SVA]) which is a highly lipophilic compound with extremely low water solubility and bioavailability.Methods: LogD values of SVA and SVL with or without bile salts were measured by liquid-liquid extraction in n-octanol/buffer systems at pH 5 and 7.4. SV concentrations in aqueous phase were determined by HPLC-DAD. Chem3D Ultra program was applied for computation of physico-chemical properties of analyzed compounds and their complexes.Results: Statistically significant decrease in both SVA and SVL logD was observed for all three studied bile salts at both selected pH. MKC exerted the most pronounced effect in the case of SVA while there were no statistically significant differences between observed bile salts for SVL. The calculated physico-chemical properties of analyzed compounds and their complexes supported experimental results.Conclusions: Our data indicate that the addition of bile salts into the n-octanol/buffer system decreases the values of SV distribution coefficient at both studied pH values. This may be the result of the formation of hydrophilic complexes increasing the solubility of SV that could consequently impact the pharmacokinetic parameters of SV and the final drug response in patients.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Drug Development and Industrial Pharmacy
T1  - The influence of bile salts on the distribution of simvastatin in the octanol/buffer system
VL  - 42
IS  - 4
SP  - 661
EP  - 667
DO  - 10.3109/03639045.2015.1067626
ER  - 

@article{
author = "Danić, Maja and Pavlović, Nebojša and Stanimirov, Bojan and Vukmirović, Sasa and Nikolić, Katarina and Agbaba, Danica and Mikov, Momir",
year = "2016",
abstract = "Introduction: Distribution coefficient (D) is useful parameter for evaluating drugs permeability properties across biological membranes, which are of importance for drugs bioavailability. Given that bile acids are intensively studied as drug permeation-modifying and -solubilizing agents, the aim of this study was to estimate the influence of sodium salts of cholic (CA), deoxycholic (DCA) and 12-monoketocholic acids (MKC) on distribution coefficient of simvastatin (SV) (lactone [SVL] and acid form [SVA]) which is a highly lipophilic compound with extremely low water solubility and bioavailability.Methods: LogD values of SVA and SVL with or without bile salts were measured by liquid-liquid extraction in n-octanol/buffer systems at pH 5 and 7.4. SV concentrations in aqueous phase were determined by HPLC-DAD. Chem3D Ultra program was applied for computation of physico-chemical properties of analyzed compounds and their complexes.Results: Statistically significant decrease in both SVA and SVL logD was observed for all three studied bile salts at both selected pH. MKC exerted the most pronounced effect in the case of SVA while there were no statistically significant differences between observed bile salts for SVL. The calculated physico-chemical properties of analyzed compounds and their complexes supported experimental results.Conclusions: Our data indicate that the addition of bile salts into the n-octanol/buffer system decreases the values of SV distribution coefficient at both studied pH values. This may be the result of the formation of hydrophilic complexes increasing the solubility of SV that could consequently impact the pharmacokinetic parameters of SV and the final drug response in patients.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Drug Development and Industrial Pharmacy",
title = "The influence of bile salts on the distribution of simvastatin in the octanol/buffer system",
volume = "42",
number = "4",
pages = "661-667",
doi = "10.3109/03639045.2015.1067626"
}

Danić, M., Pavlović, N., Stanimirov, B., Vukmirović, S., Nikolić, K., Agbaba, D.,& Mikov, M.. (2016). The influence of bile salts on the distribution of simvastatin in the octanol/buffer system. in Drug Development and Industrial Pharmacy
Taylor & Francis Ltd, Abingdon., 42(4), 661-667.
https://doi.org/10.3109/03639045.2015.1067626

Danić M, Pavlović N, Stanimirov B, Vukmirović S, Nikolić K, Agbaba D, Mikov M. The influence of bile salts on the distribution of simvastatin in the octanol/buffer system. in Drug Development and Industrial Pharmacy. 2016;42(4):661-667.
doi:10.3109/03639045.2015.1067626 .

Danić, Maja, Pavlović, Nebojša, Stanimirov, Bojan, Vukmirović, Sasa, Nikolić, Katarina, Agbaba, Danica, Mikov, Momir, "The influence of bile salts on the distribution of simvastatin in the octanol/buffer system" in Drug Development and Industrial Pharmacy, 42, no. 4 (2016):661-667,
https://doi.org/10.3109/03639045.2015.1067626 . .

TY  - JOUR
AU  - Brkić, Jovana
AU  - Tasić, Ljiljana
AU  - Jokić, Ivana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2508
AB  - Between 25% and 50% of hospitalized patients receive antibiotics. Some studies estimate that 25-68% of hospital antibiotic prescribing is suboptimal. The aim of this study was to analyse antibiotic use in Medical Center 'Bežanijska Kosa'. For the period 2008-2012, yearly data on antibiotic use in inpatients were obtained from the database of the hospital pharmacy and expressed as DDD per 100 bed-days. The total antibiotic use varied during the study period from 62,3 to 65,6 DDD per 100 bed-days. The most frequently used antibiotics were cephalosporins, followed by fluoroquinolones, penicillins and aminoglycosides. Ceftriaxone was the most frequently prescribed antibiotic. The findings emphasize the need for effective measures to reduce widespread antibiotic misusage in hospitals.
AB  - Između 25% i 50 % hospitalizovanih pacijenata prima antibiotike. Neke studije procenjuju da je 25-68% antibiotika u Bolnicama propisano neadekvatno. Cilj ovog rada je bio da se Analizira upotreba antibiotika u Kliničko-bolničkom centru 'Bežanijska kosa'. Za period od 2008. do 2012. godine podaci o upotrebi antibiotika na godišnjem nivou su dobijeni iz baze podataka bolničke apoteke i izraženi kao DDD/100 postelja/dan. U toku petogodišnjeg perioda praćenja, ukupna upotreba antibiotika se kretala od 62,3do 65,6 DDD/100 postelja/dan. Najčešće propisivani antibiotici su bili cefalosporini, a zatim fluorohinoloni, penicilini i aminoglikozidi. Ceftriakson je bio najčešće propisivani antibiotik. Ovi rezultati ističu potrebu za sprovođenjem efikasnih mera kako bi se smanjila široko rasprostranjena neadekvatna upotreba antibiotika u stacionarnim zdravstvenim ustanovama.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Rational use of antibiotics in stationary health care institution: Case study
T1  - Racionalna upotreba antibiotika u bolničkim uslovima - studija slučaja
VL  - 65
IS  - 1
SP  - 58
EP  - 71
DO  - 10.5937/arhfarm1501058B
ER  - 

@article{
author = "Brkić, Jovana and Tasić, Ljiljana and Jokić, Ivana",
year = "2015",
abstract = "Between 25% and 50% of hospitalized patients receive antibiotics. Some studies estimate that 25-68% of hospital antibiotic prescribing is suboptimal. The aim of this study was to analyse antibiotic use in Medical Center 'Bežanijska Kosa'. For the period 2008-2012, yearly data on antibiotic use in inpatients were obtained from the database of the hospital pharmacy and expressed as DDD per 100 bed-days. The total antibiotic use varied during the study period from 62,3 to 65,6 DDD per 100 bed-days. The most frequently used antibiotics were cephalosporins, followed by fluoroquinolones, penicillins and aminoglycosides. Ceftriaxone was the most frequently prescribed antibiotic. The findings emphasize the need for effective measures to reduce widespread antibiotic misusage in hospitals., Između 25% i 50 % hospitalizovanih pacijenata prima antibiotike. Neke studije procenjuju da je 25-68% antibiotika u Bolnicama propisano neadekvatno. Cilj ovog rada je bio da se Analizira upotreba antibiotika u Kliničko-bolničkom centru 'Bežanijska kosa'. Za period od 2008. do 2012. godine podaci o upotrebi antibiotika na godišnjem nivou su dobijeni iz baze podataka bolničke apoteke i izraženi kao DDD/100 postelja/dan. U toku petogodišnjeg perioda praćenja, ukupna upotreba antibiotika se kretala od 62,3do 65,6 DDD/100 postelja/dan. Najčešće propisivani antibiotici su bili cefalosporini, a zatim fluorohinoloni, penicilini i aminoglikozidi. Ceftriakson je bio najčešće propisivani antibiotik. Ovi rezultati ističu potrebu za sprovođenjem efikasnih mera kako bi se smanjila široko rasprostranjena neadekvatna upotreba antibiotika u stacionarnim zdravstvenim ustanovama.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Rational use of antibiotics in stationary health care institution: Case study, Racionalna upotreba antibiotika u bolničkim uslovima - studija slučaja",
volume = "65",
number = "1",
pages = "58-71",
doi = "10.5937/arhfarm1501058B"
}

Brkić, J., Tasić, L.,& Jokić, I.. (2015). Rational use of antibiotics in stationary health care institution: Case study. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 65(1), 58-71.
https://doi.org/10.5937/arhfarm1501058B

Brkić J, Tasić L, Jokić I. Rational use of antibiotics in stationary health care institution: Case study. in Arhiv za farmaciju. 2015;65(1):58-71.
doi:10.5937/arhfarm1501058B .

Brkić, Jovana, Tasić, Ljiljana, Jokić, Ivana, "Rational use of antibiotics in stationary health care institution: Case study" in Arhiv za farmaciju, 65, no. 1 (2015):58-71,
https://doi.org/10.5937/arhfarm1501058B . .

TY  - JOUR
AU  - Živković, Marija
AU  - Lakić, Dragana
AU  - Tadić, Ivana
AU  - Odalović, Marina
AU  - Bogavac-Stanojević, Nataša
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2523
AB  - Empirical application of antifungal drugs in the treatment of invasive fungal infections (IFI) in febrile neutropenia represent significant cost, but it is essential in patients with leukemia and after hematopoietic stem cell transplantation. Numerous clinical studies have shown little difference in the efficacy of amphotericin B and caspofungin in IFI empirical therapy, but it does not reflect their cost-effectiveness. The aim of this study was to compare the costeffectiveness of caspofungin and amphotericin B lipid complex (ABLC) in the empirical antifungal therapy in patients with febrile neutropenia using model-decision tree, from the perspective of the National Health Insurance Fund (NHIF). We used the cost-effectiveness analysis, for a period of 14 days of therapy. In model we combined data on efficacy from randomized clinical trials, while the costs were taken from the Drug list or service fee NHIF. The total cost per additional cured fungal infection with caspofungin was 639,750.06 RSD, while with ABLC was 2,153,403.61 RSD. In the sensitivity analysis, using different weights of patients (50kg or 70kg) and different doses of ABLC, caspofungin was again most cost-effective strategy for empirical antifungal therapy. Caspofungin, in addition to a better safety profile, is more cost-efficient than ABLC. This fact should be kept in mind when choosing a therapy for the treatment of IFI in patients with febrile neutropenia.
AB  - Empirijska primena antimikotika u terapiji invazivnih gljivičnih infekcija (IGI) u febrilnoj neutropeniji predstavlja značajan trošak, ali je neophodna kod pacijenata sa leukemijom i nakon transplantacije matičnih ćelija hematopoeze. Brojne kliničke studije pokazale su male razlike u efikasnosti amfotericina B i kaspofungina u empirijskoj terapiji IGI, ali to ne oslikava u pravoj meri odnos trošak-efektivnost. Cilj rada je bio poređenje isplativosti kaspofungina i amfotericina B lipidni kompleks (ABLC) u empirijskoj antigljivičnoj terapiji kod pacijenata sa febrilnom neutropenijom kroz model-drvo odlučivanja, a iz perspektive Republičkog fonda za zdravstveno osiguranje (RFZO). Primenjena je analiza isplativosti, (cost-effectiveness analsys - CEA), za period od 14 dana terapije. U modelu su kombinovani podaci o efikasnosti iz randomizovanih kliničkih studija, dok su troškovi uzeti iz važećeg cenovnika zdravstvenih usluga i Liste lekova RFZO. Ukupan trošak po dodatno izlečenoj gljivičnoj infekciji za kaspofungin iznosi 639.750,06 RSD, dok je za ABLC 2.153.403,61 RSD. U analizi osetljivosti, primenom različite telesne težine pacijenata (50kg ili 70kg) i različite doze ABLC, kaspofungin je ponovo bio isplativija strategija empirijske antigljivične terapije. Kaspofungin, pored boljeg bezbednosnog profila je i troškovno isplativiji od ABLC. Ovu činjenicu bi trebalo imati u vidu prilikom odabira terapije za lečenje IGI kod pacijenata sa febrilnom neutropenijom.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - A pharmacoeconomic evaluation of capsofungin and amphotericin B for intravenous infusion for treatment of systemic fungal infection
T1  - Farmakoekonomska evaluacija primene rastvora za infuziju kaspofungina i amfotericina B u terapiji teških sistemskih mikoza
VL  - 65
IS  - 1
SP  - 33
EP  - 46
DO  - 10.5937/arhfarm1501033Z
ER  - 

@article{
author = "Živković, Marija and Lakić, Dragana and Tadić, Ivana and Odalović, Marina and Bogavac-Stanojević, Nataša",
year = "2015",
abstract = "Empirical application of antifungal drugs in the treatment of invasive fungal infections (IFI) in febrile neutropenia represent significant cost, but it is essential in patients with leukemia and after hematopoietic stem cell transplantation. Numerous clinical studies have shown little difference in the efficacy of amphotericin B and caspofungin in IFI empirical therapy, but it does not reflect their cost-effectiveness. The aim of this study was to compare the costeffectiveness of caspofungin and amphotericin B lipid complex (ABLC) in the empirical antifungal therapy in patients with febrile neutropenia using model-decision tree, from the perspective of the National Health Insurance Fund (NHIF). We used the cost-effectiveness analysis, for a period of 14 days of therapy. In model we combined data on efficacy from randomized clinical trials, while the costs were taken from the Drug list or service fee NHIF. The total cost per additional cured fungal infection with caspofungin was 639,750.06 RSD, while with ABLC was 2,153,403.61 RSD. In the sensitivity analysis, using different weights of patients (50kg or 70kg) and different doses of ABLC, caspofungin was again most cost-effective strategy for empirical antifungal therapy. Caspofungin, in addition to a better safety profile, is more cost-efficient than ABLC. This fact should be kept in mind when choosing a therapy for the treatment of IFI in patients with febrile neutropenia., Empirijska primena antimikotika u terapiji invazivnih gljivičnih infekcija (IGI) u febrilnoj neutropeniji predstavlja značajan trošak, ali je neophodna kod pacijenata sa leukemijom i nakon transplantacije matičnih ćelija hematopoeze. Brojne kliničke studije pokazale su male razlike u efikasnosti amfotericina B i kaspofungina u empirijskoj terapiji IGI, ali to ne oslikava u pravoj meri odnos trošak-efektivnost. Cilj rada je bio poređenje isplativosti kaspofungina i amfotericina B lipidni kompleks (ABLC) u empirijskoj antigljivičnoj terapiji kod pacijenata sa febrilnom neutropenijom kroz model-drvo odlučivanja, a iz perspektive Republičkog fonda za zdravstveno osiguranje (RFZO). Primenjena je analiza isplativosti, (cost-effectiveness analsys - CEA), za period od 14 dana terapije. U modelu su kombinovani podaci o efikasnosti iz randomizovanih kliničkih studija, dok su troškovi uzeti iz važećeg cenovnika zdravstvenih usluga i Liste lekova RFZO. Ukupan trošak po dodatno izlečenoj gljivičnoj infekciji za kaspofungin iznosi 639.750,06 RSD, dok je za ABLC 2.153.403,61 RSD. U analizi osetljivosti, primenom različite telesne težine pacijenata (50kg ili 70kg) i različite doze ABLC, kaspofungin je ponovo bio isplativija strategija empirijske antigljivične terapije. Kaspofungin, pored boljeg bezbednosnog profila je i troškovno isplativiji od ABLC. Ovu činjenicu bi trebalo imati u vidu prilikom odabira terapije za lečenje IGI kod pacijenata sa febrilnom neutropenijom.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "A pharmacoeconomic evaluation of capsofungin and amphotericin B for intravenous infusion for treatment of systemic fungal infection, Farmakoekonomska evaluacija primene rastvora za infuziju kaspofungina i amfotericina B u terapiji teških sistemskih mikoza",
volume = "65",
number = "1",
pages = "33-46",
doi = "10.5937/arhfarm1501033Z"
}

Živković, M., Lakić, D., Tadić, I., Odalović, M.,& Bogavac-Stanojević, N.. (2015). A pharmacoeconomic evaluation of capsofungin and amphotericin B for intravenous infusion for treatment of systemic fungal infection. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 65(1), 33-46.
https://doi.org/10.5937/arhfarm1501033Z

Živković M, Lakić D, Tadić I, Odalović M, Bogavac-Stanojević N. A pharmacoeconomic evaluation of capsofungin and amphotericin B for intravenous infusion for treatment of systemic fungal infection. in Arhiv za farmaciju. 2015;65(1):33-46.
doi:10.5937/arhfarm1501033Z .

Živković, Marija, Lakić, Dragana, Tadić, Ivana, Odalović, Marina, Bogavac-Stanojević, Nataša, "A pharmacoeconomic evaluation of capsofungin and amphotericin B for intravenous infusion for treatment of systemic fungal infection" in Arhiv za farmaciju, 65, no. 1 (2015):33-46,
https://doi.org/10.5937/arhfarm1501033Z . .

TY  - JOUR
AU  - Lakić, Dragana
AU  - Tadić, Ivana
AU  - Odalović, Marina
AU  - Kolundžić, Svetlana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2522
AB  - Urinary tract infections are inflammations processes on lower or upper parts of urinary tract. Therapy of urinary tract infections differs for complicated and non-complicated infections and site of infection. The aim of this paper is pharmacoeconomic analysis of different strategies in management of urinary tract infections from the perspective of Republic Fond for Health Insurance. The decision tree was constructed to evaluate costs and effectiveness of different strategies used for treatment of non-pregnant, adult women. As a positive outcome of the treatment number of cases where simptoms disapered is used. The results implied that the least costly strategy available is empiric treatment. More expensive but with greater outcomes was the strategy involving laboratory test together with empiric treatment. Although the empiric treatment proved to be cost-effective and in accordance with current recommendations and guidelines for therapy, recognition of the impact of this strategy upon antibiotic resistance may lead to conclusion that the dipstick strategy is superior strategy.
AB  - Infekcije urinarnog trakta zahvataju donje i gornje delove urinarnog trakta. Terapija infekcija se razlikuje u zavisnosti da li su u pitanju komplikovane ili nekomplikovane infekcije kao i od mesta infekcije. Cilj ovog rada je farmakoekonomska analiza isplativosti primene različitih strategija u lečenju infekcija urinarnog trakta iz perspektive Republičkog fonda za zdravstveno osiguranje. Zarad procene troškova i efikasnosti primene različitih strategija u lečenju infekcija urinarnog trakta u odraslih žena koje nisu trudne konstruisano je drvo odlučivanja. Kao ishod lečenja posmatran je broj slučajeva u kojima je došlo do prestanka simptoma. Rezultati istraživanja su pokazali da je najisplativija strategija empirijska primena antibiotika. Nešto skuplja i efikasnija strategija je primena laboratorijskih testova uz empirijsku primenu antibiotika. Iako je empirijska primena antibiotika troškovno isplativa i u skladu sa važećim preporukama i protokolima lečenja infekcije urinarnog trakta, ukoliko se razmotri i antibiotska rezistencija kao rastući zdravstveni problem, strategija primene dipstik testa može biti superiorna.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Antibacterial therapy of the urinary tract infections: Pharmacoeconomic aspect
T1  - Upotreba antibakterijskih lekova u lečenju infekcija urinarnog trakta - farmakoekonomski aspect
VL  - 65
IS  - 1
SP  - 47
EP  - 57
DO  - 10.5937/arhfarm1501047L
ER  - 

@article{
author = "Lakić, Dragana and Tadić, Ivana and Odalović, Marina and Kolundžić, Svetlana",
year = "2015",
abstract = "Urinary tract infections are inflammations processes on lower or upper parts of urinary tract. Therapy of urinary tract infections differs for complicated and non-complicated infections and site of infection. The aim of this paper is pharmacoeconomic analysis of different strategies in management of urinary tract infections from the perspective of Republic Fond for Health Insurance. The decision tree was constructed to evaluate costs and effectiveness of different strategies used for treatment of non-pregnant, adult women. As a positive outcome of the treatment number of cases where simptoms disapered is used. The results implied that the least costly strategy available is empiric treatment. More expensive but with greater outcomes was the strategy involving laboratory test together with empiric treatment. Although the empiric treatment proved to be cost-effective and in accordance with current recommendations and guidelines for therapy, recognition of the impact of this strategy upon antibiotic resistance may lead to conclusion that the dipstick strategy is superior strategy., Infekcije urinarnog trakta zahvataju donje i gornje delove urinarnog trakta. Terapija infekcija se razlikuje u zavisnosti da li su u pitanju komplikovane ili nekomplikovane infekcije kao i od mesta infekcije. Cilj ovog rada je farmakoekonomska analiza isplativosti primene različitih strategija u lečenju infekcija urinarnog trakta iz perspektive Republičkog fonda za zdravstveno osiguranje. Zarad procene troškova i efikasnosti primene različitih strategija u lečenju infekcija urinarnog trakta u odraslih žena koje nisu trudne konstruisano je drvo odlučivanja. Kao ishod lečenja posmatran je broj slučajeva u kojima je došlo do prestanka simptoma. Rezultati istraživanja su pokazali da je najisplativija strategija empirijska primena antibiotika. Nešto skuplja i efikasnija strategija je primena laboratorijskih testova uz empirijsku primenu antibiotika. Iako je empirijska primena antibiotika troškovno isplativa i u skladu sa važećim preporukama i protokolima lečenja infekcije urinarnog trakta, ukoliko se razmotri i antibiotska rezistencija kao rastući zdravstveni problem, strategija primene dipstik testa može biti superiorna.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Antibacterial therapy of the urinary tract infections: Pharmacoeconomic aspect, Upotreba antibakterijskih lekova u lečenju infekcija urinarnog trakta - farmakoekonomski aspect",
volume = "65",
number = "1",
pages = "47-57",
doi = "10.5937/arhfarm1501047L"
}

Lakić, D., Tadić, I., Odalović, M.,& Kolundžić, S.. (2015). Antibacterial therapy of the urinary tract infections: Pharmacoeconomic aspect. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 65(1), 47-57.
https://doi.org/10.5937/arhfarm1501047L

Lakić D, Tadić I, Odalović M, Kolundžić S. Antibacterial therapy of the urinary tract infections: Pharmacoeconomic aspect. in Arhiv za farmaciju. 2015;65(1):47-57.
doi:10.5937/arhfarm1501047L .

Lakić, Dragana, Tadić, Ivana, Odalović, Marina, Kolundžić, Svetlana, "Antibacterial therapy of the urinary tract infections: Pharmacoeconomic aspect" in Arhiv za farmaciju, 65, no. 1 (2015):47-57,
https://doi.org/10.5937/arhfarm1501047L . .

TY  - JOUR
AU  - Odalović, Marina
AU  - Tasić, Ljiljana
AU  - Krajnović, Dušanka
AU  - Vezmar-Kovačević, Sandra
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2511
AB  - Introduction. The use of drugs in pregnancy, despite to potential risks, is a very common and necessary. Pharmacists' interventions in the process of drug dispensing to pregnant women may be essential for the use of the safest drug for the foetus. The aim of the study was to explore Serbia pharmacists' interventions in the population of pregnant women and to suggest measures for interventions advancement. Methods. Internet-based study was performed during the period April 1st - May 31th, 2012. The questionnaire, specially designed according to aims of the study, was distributed to pharmacists via their e-mails. Participation in the study was anonymous and voluntarily. Data according to pharmacists' socio-demographics characteristics and their experiences in interventions during drug dispensing to pregnant women were gathered. SPSS software was used in data analysis. Results. The questionnaire was distributed to 2972 pharmacists, 4% accepted to participate. More than half of participants, 57.6%, had experience with dispensing of drug to pregnant women which is not safe for the foetus. In total 47.9% of all participants made a contact with prescriber and warned about potential risk of proscribed drug for the foetus. A less than a half of such interventions, 40.7 %, ended with the change in therapy. Conclusion. Pharmacists could give a significant contribution to prevention of unsafe drug use trough the interventions and consultation with physicians about drug safety for the fetus which is the fondation for development of pharmacy servises derectited to pregnant women.
AB  - Upotreba lekova u trudnoći je, uprkos potencijalnim rizicima, veoma česta i neophodna. Intervencije farmaceuta u procesu izdavanja lekova trudnicama mogu biti ključne za upotrebu što bezbednijih lekova za plod. Cilj studije bio je da se ispitaju intervencije farmaceuta u Srbiji kod izdavanja lekova trudnicama i predlože mere za unapređenje navedenih intervencija. Metodologija. U periodu 1. april - 31. maj 2012. godine sprovedeno je istraživanje tokom kog je diplomiranim farmaceutima, putem elektronske pošte, distribuiran upitnik namenski kreiran prema ciljevima istraživanja. Popunjavanje upitnika bilo je anonimno i dobrovoljno. Prikupljeni su socio-demografski podaci o farmaceutima, i podaci o njihovim intervencijama tokom izdavanja lekova trudnicama. Obrada podataka rađena je upotrebom SPSS softvera. Rezultati. Od ukupno 2972 farmaceuta kojima je upitnik dostavljen, 4% prihvatilo je da učestvuje u istraživanju i popunilo je upitnik. Više od polovine učesnika istraživanja, 57,6%, susrelo se tokom svog radnog veka sa propisivanjem nebezbednog leka za plod na receptu namenjenom trudnici. Ukupno 47,9% od ukupnog broja ispitanih farmaceuta kontaktiralo je lekara zbog propisivanja nebezbednog leka trudnici, tj. sprovela je intervenciju i upozorila lekara o potencijalnim rizicima od propisane terapije za plod. Nešto manje od polovine intervencija, 40,7%, završeno je promenom terapije od strane lekara. Zaključak. Farmaceuti mogu dati značajan doprinos u sprečavanju upotrebe nebezbednih lekova za plod putem intervencije informisanja lekara o bezbednosti lekova za plod što predstavlja osnovu za razvoj farmaceutske usluge posvećene trudnicama.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Pharmacists' interventions in the population of pregnant women and recomandations for pharmacy practice impoveme
T1  - Intervencije farmaceuta u populaciji trudnica i preporuke za unapređenje
VL  - 65
IS  - 1
SP  - 17
EP  - 32
DO  - 10.5937/arhfarm1501017O
ER  - 

@article{
author = "Odalović, Marina and Tasić, Ljiljana and Krajnović, Dušanka and Vezmar-Kovačević, Sandra",
year = "2015",
abstract = "Introduction. The use of drugs in pregnancy, despite to potential risks, is a very common and necessary. Pharmacists' interventions in the process of drug dispensing to pregnant women may be essential for the use of the safest drug for the foetus. The aim of the study was to explore Serbia pharmacists' interventions in the population of pregnant women and to suggest measures for interventions advancement. Methods. Internet-based study was performed during the period April 1st - May 31th, 2012. The questionnaire, specially designed according to aims of the study, was distributed to pharmacists via their e-mails. Participation in the study was anonymous and voluntarily. Data according to pharmacists' socio-demographics characteristics and their experiences in interventions during drug dispensing to pregnant women were gathered. SPSS software was used in data analysis. Results. The questionnaire was distributed to 2972 pharmacists, 4% accepted to participate. More than half of participants, 57.6%, had experience with dispensing of drug to pregnant women which is not safe for the foetus. In total 47.9% of all participants made a contact with prescriber and warned about potential risk of proscribed drug for the foetus. A less than a half of such interventions, 40.7 %, ended with the change in therapy. Conclusion. Pharmacists could give a significant contribution to prevention of unsafe drug use trough the interventions and consultation with physicians about drug safety for the fetus which is the fondation for development of pharmacy servises derectited to pregnant women., Upotreba lekova u trudnoći je, uprkos potencijalnim rizicima, veoma česta i neophodna. Intervencije farmaceuta u procesu izdavanja lekova trudnicama mogu biti ključne za upotrebu što bezbednijih lekova za plod. Cilj studije bio je da se ispitaju intervencije farmaceuta u Srbiji kod izdavanja lekova trudnicama i predlože mere za unapređenje navedenih intervencija. Metodologija. U periodu 1. april - 31. maj 2012. godine sprovedeno je istraživanje tokom kog je diplomiranim farmaceutima, putem elektronske pošte, distribuiran upitnik namenski kreiran prema ciljevima istraživanja. Popunjavanje upitnika bilo je anonimno i dobrovoljno. Prikupljeni su socio-demografski podaci o farmaceutima, i podaci o njihovim intervencijama tokom izdavanja lekova trudnicama. Obrada podataka rađena je upotrebom SPSS softvera. Rezultati. Od ukupno 2972 farmaceuta kojima je upitnik dostavljen, 4% prihvatilo je da učestvuje u istraživanju i popunilo je upitnik. Više od polovine učesnika istraživanja, 57,6%, susrelo se tokom svog radnog veka sa propisivanjem nebezbednog leka za plod na receptu namenjenom trudnici. Ukupno 47,9% od ukupnog broja ispitanih farmaceuta kontaktiralo je lekara zbog propisivanja nebezbednog leka trudnici, tj. sprovela je intervenciju i upozorila lekara o potencijalnim rizicima od propisane terapije za plod. Nešto manje od polovine intervencija, 40,7%, završeno je promenom terapije od strane lekara. Zaključak. Farmaceuti mogu dati značajan doprinos u sprečavanju upotrebe nebezbednih lekova za plod putem intervencije informisanja lekara o bezbednosti lekova za plod što predstavlja osnovu za razvoj farmaceutske usluge posvećene trudnicama.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Pharmacists' interventions in the population of pregnant women and recomandations for pharmacy practice impoveme, Intervencije farmaceuta u populaciji trudnica i preporuke za unapređenje",
volume = "65",
number = "1",
pages = "17-32",
doi = "10.5937/arhfarm1501017O"
}

Odalović, M., Tasić, L., Krajnović, D.,& Vezmar-Kovačević, S.. (2015). Pharmacists' interventions in the population of pregnant women and recomandations for pharmacy practice impoveme. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 65(1), 17-32.
https://doi.org/10.5937/arhfarm1501017O

Odalović M, Tasić L, Krajnović D, Vezmar-Kovačević S. Pharmacists' interventions in the population of pregnant women and recomandations for pharmacy practice impoveme. in Arhiv za farmaciju. 2015;65(1):17-32.
doi:10.5937/arhfarm1501017O .

Odalović, Marina, Tasić, Ljiljana, Krajnović, Dušanka, Vezmar-Kovačević, Sandra, "Pharmacists' interventions in the population of pregnant women and recomandations for pharmacy practice impoveme" in Arhiv za farmaciju, 65, no. 1 (2015):17-32,
https://doi.org/10.5937/arhfarm1501017O . .

TY  - JOUR
AU  - Brkić, Jovana
AU  - Tasić, Ljiljana
AU  - Krajnović, Dušanka
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2296
AB  - Pharmacists as the most accessible health care professionals in outpatient settings can improve palliative patient care. The aim of this review was to assess utility of pharmacists (the effectiveness of pharmacists' interventions) on clinical outcomes of patients in palliative care at all levels of health care and in home care. Two electronic databases were searched: PubMed and SCOPUS (last searched August 2014). Primary studies, of any type of research design, in English, related to clinical outcomes of patients in palliative care and pharmacists' interventions were eligible. Studies that used surrogate outcome measures, such as number of pharmacists' recommendations were excluded. A total of 764 reports were found, and only three of them met our inclusion criteria. All of them assessed effects of pharmacists' interventions in outpatient settings and were case series. Symptoms improvement and stabilization of patients' conditions has been the main utility of pharmacists' interventions. Assessed quality of two studies was moderate, and one study had low quality. As number of studies and quality of the evidence were limited, and results of reviewed studies indicate that pharmacists' interventions potentially could improve clinical outcomes of patients in palliative care, more research is needed to provide evidences in this field.
AB  - Farmaceuti, kao najdostupniji zdravstveni radnici u vanbolničkim uslovima, mogu unaprediti zdravstvenu zaštitu pacijenata u palijativnoj nezi. Cilj ovog pregleda bio je da se proceni učinak farmaceuta (efektivnost intervencija farmaceuta) na kliničke ishode kod pacijenata u palijativnoj nezi na svim nivoima zdravstvene zaštite i u kućnim uslovima. Pretražene su dve elektronske baze naučnih radova: PubMed i SCOPUS (poslednji put u avgustu 2014. godine). Uključeni su originalni naučni radovi na engleskom jeziku, bez obzira na dizajn studije, koji se odnose na kliničke ishode kod pacijenata u palijativnoj nezi i intervencije farmaceuta. Studije koje su koristile surogatne mere ishoda, kao što je broj preporuka farmaceuta, su isključene. Od inicijalno pronađena 764 rada, samo tri su zadovoljila kriterijume za uključivanje u pregled, i svi su se odnosili na intervencije farmaceuta u vanbolničkim uslovima. Sve 3 studije su bile prikazi studija slučajeva. U svim studijama intervencije farmaceuta su dovele do stabilazicije ili poboljšanja simptoma kod pacijenata. Procenjen kvalitet dve studije je bio srednji, a jedna studija je bila lošeg kvaliteta. Kako je broj studija i nivo dokaza ograničen, a rezultati studija ukazuju da intervencije farmaceuta potencijalno mogu imati pozitivan uticaj na kliničke ishode kod pacijenata u palijativnoj nezi, potrebna su dalja istraživanja u ovoj oblasti.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Utility of pharmacists on clinical outcomes of patients in palliative care: A short review
T1  - Učinak farmaceuta na kliničke ishode kod pacijenata u palijativnoj nezi - kratak pregled
VL  - 64
IS  - 6
SP  - 487
EP  - 498
DO  - 10.5937/arhfarm1406487B
ER  - 

@article{
author = "Brkić, Jovana and Tasić, Ljiljana and Krajnović, Dušanka",
year = "2014",
abstract = "Pharmacists as the most accessible health care professionals in outpatient settings can improve palliative patient care. The aim of this review was to assess utility of pharmacists (the effectiveness of pharmacists' interventions) on clinical outcomes of patients in palliative care at all levels of health care and in home care. Two electronic databases were searched: PubMed and SCOPUS (last searched August 2014). Primary studies, of any type of research design, in English, related to clinical outcomes of patients in palliative care and pharmacists' interventions were eligible. Studies that used surrogate outcome measures, such as number of pharmacists' recommendations were excluded. A total of 764 reports were found, and only three of them met our inclusion criteria. All of them assessed effects of pharmacists' interventions in outpatient settings and were case series. Symptoms improvement and stabilization of patients' conditions has been the main utility of pharmacists' interventions. Assessed quality of two studies was moderate, and one study had low quality. As number of studies and quality of the evidence were limited, and results of reviewed studies indicate that pharmacists' interventions potentially could improve clinical outcomes of patients in palliative care, more research is needed to provide evidences in this field., Farmaceuti, kao najdostupniji zdravstveni radnici u vanbolničkim uslovima, mogu unaprediti zdravstvenu zaštitu pacijenata u palijativnoj nezi. Cilj ovog pregleda bio je da se proceni učinak farmaceuta (efektivnost intervencija farmaceuta) na kliničke ishode kod pacijenata u palijativnoj nezi na svim nivoima zdravstvene zaštite i u kućnim uslovima. Pretražene su dve elektronske baze naučnih radova: PubMed i SCOPUS (poslednji put u avgustu 2014. godine). Uključeni su originalni naučni radovi na engleskom jeziku, bez obzira na dizajn studije, koji se odnose na kliničke ishode kod pacijenata u palijativnoj nezi i intervencije farmaceuta. Studije koje su koristile surogatne mere ishoda, kao što je broj preporuka farmaceuta, su isključene. Od inicijalno pronađena 764 rada, samo tri su zadovoljila kriterijume za uključivanje u pregled, i svi su se odnosili na intervencije farmaceuta u vanbolničkim uslovima. Sve 3 studije su bile prikazi studija slučajeva. U svim studijama intervencije farmaceuta su dovele do stabilazicije ili poboljšanja simptoma kod pacijenata. Procenjen kvalitet dve studije je bio srednji, a jedna studija je bila lošeg kvaliteta. Kako je broj studija i nivo dokaza ograničen, a rezultati studija ukazuju da intervencije farmaceuta potencijalno mogu imati pozitivan uticaj na kliničke ishode kod pacijenata u palijativnoj nezi, potrebna su dalja istraživanja u ovoj oblasti.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Utility of pharmacists on clinical outcomes of patients in palliative care: A short review, Učinak farmaceuta na kliničke ishode kod pacijenata u palijativnoj nezi - kratak pregled",
volume = "64",
number = "6",
pages = "487-498",
doi = "10.5937/arhfarm1406487B"
}

Brkić, J., Tasić, L.,& Krajnović, D.. (2014). Utility of pharmacists on clinical outcomes of patients in palliative care: A short review. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 64(6), 487-498.
https://doi.org/10.5937/arhfarm1406487B

Brkić J, Tasić L, Krajnović D. Utility of pharmacists on clinical outcomes of patients in palliative care: A short review. in Arhiv za farmaciju. 2014;64(6):487-498.
doi:10.5937/arhfarm1406487B .

Brkić, Jovana, Tasić, Ljiljana, Krajnović, Dušanka, "Utility of pharmacists on clinical outcomes of patients in palliative care: A short review" in Arhiv za farmaciju, 64, no. 6 (2014):487-498,
https://doi.org/10.5937/arhfarm1406487B . .

TY  - JOUR
AU  - Lakić, Dragana
AU  - Tadić, Ivana
AU  - Odalović, Marina
AU  - Tasić, Ljiljana
AU  - Sabo, Ana
AU  - Mećava, Aleksandra
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2244
AB  - Introduction. Respiratory infections are the most common infections in children. The aims of the study were to analyze the use of antibiotics for respiratory infections in the period 2008 - 2010 in children's population in region of Niš and to estimate the rational use of antibiotics in relation to the recommendations of the National Guidelines for physicians in primary care. Material and methods. Data source was a Pharmacy Niš database. Antibiotics prescriptions were selected for the following diagnoses: H65-H75 (acute otitis media, mastoiditis), J01 (acute sinusitis), J02-J03 (tonsillopharyngitis), J12-J18 (community acquired pneumonia), J20 (acute bronchitis), J32 (chronic sinusitis), J42 (chronic bronchitis). Antibiotic consumption was expressed in defined daily dose/1000 inhabitants/day. Results. The most widely prescribed antibiotic for the treatment of upper respiratory tract infections in children during the three years was amoxicillin (34.63; 32.50 and 31.00 defined daily dose/1000 inhabitants/day in 2008, 2009 and 2010, respectively). In the treatment of infections of the middle ear and mastoid, the combination of amoxicillin and clavulanic acid, was the most prescribed antibiotics (60% of total consumption of antibiotics for this indication). Azithromycin was the most widely prescribed antibiotic for the treatment of lower respiratory tract infections in children during the observed period (6.92; 8.20 and 7.18 defined daily dose/1000 inhabitans/day in 2008, 2009 and 2010, respectively). Conclusion. Recommendations of national guidelines are not complied with the treatment of upper and lower respiratory infections in the children population in region of Niš. This could be a sign of potentially irrational use of antibiotics that need to be further examined. Education of physicians can influence irrational use of antibiotics.
AB  - Uvod. Infekcije respiratornog sistema predstavljaju najčešće infekcije kod dece. Ciljevi ovog rada jesu analiza potrošnje antibiotika u lečenju infekcija gornjih i donjih respiratornih puteva kod dece u Nišavskom okrugu i procena racionalnosti upotrebe antibiotika u odnosu na preporuke Nacionalnog vodiča za lekare u primarnoj zdravstvenoj zaštiti. Materijal i metode. Kao izvor podataka korišćena je baza podataka Apoteke Niš za period 2008-2010. godine. Selektovani su svi izdati recepti antibiotika propisani deci starosti 0-19 godina za terapiju infekcija respiratornog trakta uključujući infekcije srednjeg uva ((H65-H75 (akutni otitis media i mastoiditis), J01 (akutni sinuzitis), J02-J03 (tonzilofaringitis), J32 (hronični sinuzitis) (J12-J18 (blaga do umerena pneumonija izazvana vanbolničkim uzročnikom), J20 (akutni bronhitis), J42 (hronični bronhitis)). Potrošnja je izražena u definitivnoj dnevnoj dozi/1 000 stanovnika/dan. Rezultati. Najpropisivaniji antibiotik za terapiju infekcija gornjeg respiratornog trakta kod dece u posmatranom periodu bio je amoksicilin (34,63; 32,5 i 31 definitivnoj dnevnoj dozi/1 000 stanovnika/ dan tokom 2008, 2009. i 2010. godine). Za terapiju infekcije srednjeg uva i mastoidnog nastavka najčešće je korišćena kombinacija amoksicilina i klavulanske kiseline (60% ukupne potrošnje svih antibiotika za ovu indikaciju). Azitromicin je bio najpropisivaniji antibiotik za terapiju infekcija donjeg respiratornog trakta kod dece tokom posmatranog perioda (6,92; 8,2 i 7,18 definitivnoj dnevnoj dozi/1 000 stanovnika/dan tokom 2008, 2009. i 2010. godine). Zaključak. Preporuke nacionalnih vodiča nisu poštovane ni u slučaju terapije gornjih ni donjih respiratornih infekcija kod dece u Nišavskom regionu. To može biti znak potencijalno neracionalne upotrebe antibiotika koju je potrebno dodatno istražiti. Dodatna edukacija lekara mogla bi uticati na smanjivanje neracionalne upotrebe antibiotika.
PB  - Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad
T2  - Medicinski pregled
T1  - Analysis of antibiotic consumption for treating respiratory tract infections in children and compliance with the national clinical guidelines
T1  - Analiza potrošnje antibiotika za lečenje infekcija respiratornog trakta u dečjoj populaciji i usklađenosti sa nacionalnim vodičima dobre kliničke prakse
VL  - 67
IS  - 9-10
SP  - 282
EP  - 289
DO  - 10.2298/MPNS1410282L
ER  - 

@article{
author = "Lakić, Dragana and Tadić, Ivana and Odalović, Marina and Tasić, Ljiljana and Sabo, Ana and Mećava, Aleksandra",
year = "2014",
abstract = "Introduction. Respiratory infections are the most common infections in children. The aims of the study were to analyze the use of antibiotics for respiratory infections in the period 2008 - 2010 in children's population in region of Niš and to estimate the rational use of antibiotics in relation to the recommendations of the National Guidelines for physicians in primary care. Material and methods. Data source was a Pharmacy Niš database. Antibiotics prescriptions were selected for the following diagnoses: H65-H75 (acute otitis media, mastoiditis), J01 (acute sinusitis), J02-J03 (tonsillopharyngitis), J12-J18 (community acquired pneumonia), J20 (acute bronchitis), J32 (chronic sinusitis), J42 (chronic bronchitis). Antibiotic consumption was expressed in defined daily dose/1000 inhabitants/day. Results. The most widely prescribed antibiotic for the treatment of upper respiratory tract infections in children during the three years was amoxicillin (34.63; 32.50 and 31.00 defined daily dose/1000 inhabitants/day in 2008, 2009 and 2010, respectively). In the treatment of infections of the middle ear and mastoid, the combination of amoxicillin and clavulanic acid, was the most prescribed antibiotics (60% of total consumption of antibiotics for this indication). Azithromycin was the most widely prescribed antibiotic for the treatment of lower respiratory tract infections in children during the observed period (6.92; 8.20 and 7.18 defined daily dose/1000 inhabitans/day in 2008, 2009 and 2010, respectively). Conclusion. Recommendations of national guidelines are not complied with the treatment of upper and lower respiratory infections in the children population in region of Niš. This could be a sign of potentially irrational use of antibiotics that need to be further examined. Education of physicians can influence irrational use of antibiotics., Uvod. Infekcije respiratornog sistema predstavljaju najčešće infekcije kod dece. Ciljevi ovog rada jesu analiza potrošnje antibiotika u lečenju infekcija gornjih i donjih respiratornih puteva kod dece u Nišavskom okrugu i procena racionalnosti upotrebe antibiotika u odnosu na preporuke Nacionalnog vodiča za lekare u primarnoj zdravstvenoj zaštiti. Materijal i metode. Kao izvor podataka korišćena je baza podataka Apoteke Niš za period 2008-2010. godine. Selektovani su svi izdati recepti antibiotika propisani deci starosti 0-19 godina za terapiju infekcija respiratornog trakta uključujući infekcije srednjeg uva ((H65-H75 (akutni otitis media i mastoiditis), J01 (akutni sinuzitis), J02-J03 (tonzilofaringitis), J32 (hronični sinuzitis) (J12-J18 (blaga do umerena pneumonija izazvana vanbolničkim uzročnikom), J20 (akutni bronhitis), J42 (hronični bronhitis)). Potrošnja je izražena u definitivnoj dnevnoj dozi/1 000 stanovnika/dan. Rezultati. Najpropisivaniji antibiotik za terapiju infekcija gornjeg respiratornog trakta kod dece u posmatranom periodu bio je amoksicilin (34,63; 32,5 i 31 definitivnoj dnevnoj dozi/1 000 stanovnika/ dan tokom 2008, 2009. i 2010. godine). Za terapiju infekcije srednjeg uva i mastoidnog nastavka najčešće je korišćena kombinacija amoksicilina i klavulanske kiseline (60% ukupne potrošnje svih antibiotika za ovu indikaciju). Azitromicin je bio najpropisivaniji antibiotik za terapiju infekcija donjeg respiratornog trakta kod dece tokom posmatranog perioda (6,92; 8,2 i 7,18 definitivnoj dnevnoj dozi/1 000 stanovnika/dan tokom 2008, 2009. i 2010. godine). Zaključak. Preporuke nacionalnih vodiča nisu poštovane ni u slučaju terapije gornjih ni donjih respiratornih infekcija kod dece u Nišavskom regionu. To može biti znak potencijalno neracionalne upotrebe antibiotika koju je potrebno dodatno istražiti. Dodatna edukacija lekara mogla bi uticati na smanjivanje neracionalne upotrebe antibiotika.",
publisher = "Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad",
journal = "Medicinski pregled",
title = "Analysis of antibiotic consumption for treating respiratory tract infections in children and compliance with the national clinical guidelines, Analiza potrošnje antibiotika za lečenje infekcija respiratornog trakta u dečjoj populaciji i usklađenosti sa nacionalnim vodičima dobre kliničke prakse",
volume = "67",
number = "9-10",
pages = "282-289",
doi = "10.2298/MPNS1410282L"
}

Lakić, D., Tadić, I., Odalović, M., Tasić, L., Sabo, A.,& Mećava, A.. (2014). Analysis of antibiotic consumption for treating respiratory tract infections in children and compliance with the national clinical guidelines. in Medicinski pregled
Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad., 67(9-10), 282-289.
https://doi.org/10.2298/MPNS1410282L

Lakić D, Tadić I, Odalović M, Tasić L, Sabo A, Mećava A. Analysis of antibiotic consumption for treating respiratory tract infections in children and compliance with the national clinical guidelines. in Medicinski pregled. 2014;67(9-10):282-289.
doi:10.2298/MPNS1410282L .

Lakić, Dragana, Tadić, Ivana, Odalović, Marina, Tasić, Ljiljana, Sabo, Ana, Mećava, Aleksandra, "Analysis of antibiotic consumption for treating respiratory tract infections in children and compliance with the national clinical guidelines" in Medicinski pregled, 67, no. 9-10 (2014):282-289,
https://doi.org/10.2298/MPNS1410282L . .

TY  - THES
AU  - Odalović, Marina
PY  - 2013
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=1366
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:8492/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=44873231
UR  - http://nardus.mpn.gov.rs/123456789/3159
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3404
AB  - Uvod i ciljevi. Upotreba lekova u trudnoći čest je razlog brige lekara koji ihpropisuju i trudnica koje ih koriste. Iako bi bilo veoma korisno poznavati rizičnepopulacije trudnica koje imaju veću verovatnoću upotrebe lekova u toku trudnoće,mali je broj studija koje su se bavile istraživanjima u ovoj oblasti. Uloga i doprinosfarmaceuta u procesu izdavanja ili prodaje lekova trudnicama mogu biti ključni zabezbednu primenu lekova u trudnoći. Cilj disertacije bio je da se istraži upotrebalekova u periodu od šest meseci pre i tokom trudnoće, da se izvrši evaluacijaupotrebljenih lekova prema anatomsko-terapijsko-hemijskoj (ATC) klasifikaciji,prema riziku za plod i režimu izdavanja (na recept i bez recepta (samomedikacija)),zatim, da se ispita da li postoji povezanost između faktora životnogstila, socio-ekonomskih faktora i zdravstvenog stanja ispitanica i upotrebe lekovapre i tokom trudnoće, kao i da se ispita na koji način pomenuti faktori utiču naupotrebu navedenih klasa lekova. Cilj je bio i da se ispita potencijalni doprinosfarmaceuta kod upotrebe lekova u trudnoći.Metode istraživanja. Radi postizanja postavljenih ciljeva sprovedene su dvestudije. Prva studija bila je multi-centrična i sprovedena je u šest domova zdravlja ipet apoteka na teritoriji opština Vračar, Voždovac, Lazarevac, Loznica, Čačak iSubotica, u periodu mart 2009 – mart 2010. Prikupljanje podataka sprovedeno jeupitnikom specijalno dizajniranim za potrebe studije. Trudnice su upitnikpopunjavale samostalno, bez pomoći zdravstvenih radnika, anonimno, dobrovoljnoi volonterski. Prikupljeni su podaci o socio-ekonomskim karakteristikama,životnom stilu i zdravstvenom statusu ispitanica, kao i o upotrebi lekova u perioduod šest meseci pre i tokom trudnoće. Radi klasifikovanja lekova prema riziku zaplod korišćena je klasifikacija američke Agencije za hranu i lekove (Food and DrugAdministration - FDA). Upotreba lekova izražavana je kao proporcija žena izloženaleku ili ATC grupi ili podgrupi lekova. Razlike u upotrebi lekova između različitihgrupa analizirane su upotrebom McNemar-ovog testa. Univarijantna imultivarijantna logistička regresija korišćene su da bi se odredili faktori značajnopovezani sa upotrebom lekova. Kao mere povezanosti između faktora i upotrebelekova korišćeni su direktni odnos šansi (odds ratio – OR) i korigovan odnos šansi(adjusted odds ratio – aOR) uz prikazivanje 95% intervala pouzdanosti (confidenceintervals - CI)...
AB  - Background and Aims. Drug use in pregnancy is often a reason of concernfor mothers and their physicians. However, only few studies investigatedpredictors of drug use in pregnancy. The role and contribution of pharmacists inthe process of drug dispensing could be very important for improvement of safedrug use in pregnancy. The aim of dissertation was to investigate prescription andover the counter drug use among Serbian women in the 6 months beforepregnancy and in the first 6 months of pregnancy, and to evaluate the drugs usedaccording to anatomical-therapeutic-chemical classification, according to the riskfor the fetus and according to dispensing status (proscription (Rx) or over-thecounter(OTC)). The aim was also to examine if a significant association betweensocio-economic factors, life style and health status of women and drug use exist, aswell as to investigate how much these factors impact drug use before and duringpregnancy. Finally, the aim was to investigate a potential contribution ofpharmacist in safe drug use in pregnancy.Methodology. Two studies were carried out in order to gain all the aims. Thefirst study was multi-center and performed in the six maternity care units and fivecommunity pharmacies (municipalities: Vračar, Voždovac, Lazarevac, Loznica,Čačak i Subotica) during the period from March 2009–March 2010. A selfreportingquestionnaire was used as a data source. Participation in the study wasvoluntarily and anonymous. Data according to socio-economic characteristics, lifestyle, health status and drug use six months before and during pregnancy werecollected. Food and Drug Administration (FDA) risk classification system was usedto determine the risk of used drugs for the fetus. Proportion of women exposed todrugs or class of drugs. Differences between subgroups were assessed usingMcNemar’s test on paired proportions. Logistic regression was used to identifyfactors associated with medication use. Adjusted odds ratios (aOR) and 95 %confidence intervals (CI) were used as association measures. Data analysis wasperformed using SPSS software package (SPSS 18.0 for Windows, SPSS Inc.,Chicago, IL, USA). The study was performed after obtaining approval from TheBoard of Management and The Human Research Ethics Committee...
PB  - Универзитет у Београду, Фармацеутски факултет
T2  - Универзитет у Београду
T1  - Analiza uticaja životnog stila, socio-ekonomskih faktora i zdravstvenog stanja ispitanica na upotrebu lekova u trudnoći
T1  - Analysis of impact of life style, socio-economic factorsand health status on the use of medicines in pregnancy
UR  - https://hdl.handle.net/21.15107/rcub_nardus_3159
ER  - 

@phdthesis{
author = "Odalović, Marina",
year = "2013",
abstract = "Uvod i ciljevi. Upotreba lekova u trudnoći čest je razlog brige lekara koji ihpropisuju i trudnica koje ih koriste. Iako bi bilo veoma korisno poznavati rizičnepopulacije trudnica koje imaju veću verovatnoću upotrebe lekova u toku trudnoće,mali je broj studija koje su se bavile istraživanjima u ovoj oblasti. Uloga i doprinosfarmaceuta u procesu izdavanja ili prodaje lekova trudnicama mogu biti ključni zabezbednu primenu lekova u trudnoći. Cilj disertacije bio je da se istraži upotrebalekova u periodu od šest meseci pre i tokom trudnoće, da se izvrši evaluacijaupotrebljenih lekova prema anatomsko-terapijsko-hemijskoj (ATC) klasifikaciji,prema riziku za plod i režimu izdavanja (na recept i bez recepta (samomedikacija)),zatim, da se ispita da li postoji povezanost između faktora životnogstila, socio-ekonomskih faktora i zdravstvenog stanja ispitanica i upotrebe lekovapre i tokom trudnoće, kao i da se ispita na koji način pomenuti faktori utiču naupotrebu navedenih klasa lekova. Cilj je bio i da se ispita potencijalni doprinosfarmaceuta kod upotrebe lekova u trudnoći.Metode istraživanja. Radi postizanja postavljenih ciljeva sprovedene su dvestudije. Prva studija bila je multi-centrična i sprovedena je u šest domova zdravlja ipet apoteka na teritoriji opština Vračar, Voždovac, Lazarevac, Loznica, Čačak iSubotica, u periodu mart 2009 – mart 2010. Prikupljanje podataka sprovedeno jeupitnikom specijalno dizajniranim za potrebe studije. Trudnice su upitnikpopunjavale samostalno, bez pomoći zdravstvenih radnika, anonimno, dobrovoljnoi volonterski. Prikupljeni su podaci o socio-ekonomskim karakteristikama,životnom stilu i zdravstvenom statusu ispitanica, kao i o upotrebi lekova u perioduod šest meseci pre i tokom trudnoće. Radi klasifikovanja lekova prema riziku zaplod korišćena je klasifikacija američke Agencije za hranu i lekove (Food and DrugAdministration - FDA). Upotreba lekova izražavana je kao proporcija žena izloženaleku ili ATC grupi ili podgrupi lekova. Razlike u upotrebi lekova između različitihgrupa analizirane su upotrebom McNemar-ovog testa. Univarijantna imultivarijantna logistička regresija korišćene su da bi se odredili faktori značajnopovezani sa upotrebom lekova. Kao mere povezanosti između faktora i upotrebelekova korišćeni su direktni odnos šansi (odds ratio – OR) i korigovan odnos šansi(adjusted odds ratio – aOR) uz prikazivanje 95% intervala pouzdanosti (confidenceintervals - CI)..., Background and Aims. Drug use in pregnancy is often a reason of concernfor mothers and their physicians. However, only few studies investigatedpredictors of drug use in pregnancy. The role and contribution of pharmacists inthe process of drug dispensing could be very important for improvement of safedrug use in pregnancy. The aim of dissertation was to investigate prescription andover the counter drug use among Serbian women in the 6 months beforepregnancy and in the first 6 months of pregnancy, and to evaluate the drugs usedaccording to anatomical-therapeutic-chemical classification, according to the riskfor the fetus and according to dispensing status (proscription (Rx) or over-thecounter(OTC)). The aim was also to examine if a significant association betweensocio-economic factors, life style and health status of women and drug use exist, aswell as to investigate how much these factors impact drug use before and duringpregnancy. Finally, the aim was to investigate a potential contribution ofpharmacist in safe drug use in pregnancy.Methodology. Two studies were carried out in order to gain all the aims. Thefirst study was multi-center and performed in the six maternity care units and fivecommunity pharmacies (municipalities: Vračar, Voždovac, Lazarevac, Loznica,Čačak i Subotica) during the period from March 2009–March 2010. A selfreportingquestionnaire was used as a data source. Participation in the study wasvoluntarily and anonymous. Data according to socio-economic characteristics, lifestyle, health status and drug use six months before and during pregnancy werecollected. Food and Drug Administration (FDA) risk classification system was usedto determine the risk of used drugs for the fetus. Proportion of women exposed todrugs or class of drugs. Differences between subgroups were assessed usingMcNemar’s test on paired proportions. Logistic regression was used to identifyfactors associated with medication use. Adjusted odds ratios (aOR) and 95 %confidence intervals (CI) were used as association measures. Data analysis wasperformed using SPSS software package (SPSS 18.0 for Windows, SPSS Inc.,Chicago, IL, USA). The study was performed after obtaining approval from TheBoard of Management and The Human Research Ethics Committee...",
publisher = "Универзитет у Београду, Фармацеутски факултет",
journal = "Универзитет у Београду",
title = "Analiza uticaja životnog stila, socio-ekonomskih faktora i zdravstvenog stanja ispitanica na upotrebu lekova u trudnoći, Analysis of impact of life style, socio-economic factorsand health status on the use of medicines in pregnancy",
url = "https://hdl.handle.net/21.15107/rcub_nardus_3159"
}

Odalović, M.. (2013). Analiza uticaja životnog stila, socio-ekonomskih faktora i zdravstvenog stanja ispitanica na upotrebu lekova u trudnoći. in Универзитет у Београду
Универзитет у Београду, Фармацеутски факултет..
https://hdl.handle.net/21.15107/rcub_nardus_3159

Odalović M. Analiza uticaja životnog stila, socio-ekonomskih faktora i zdravstvenog stanja ispitanica na upotrebu lekova u trudnoći. in Универзитет у Београду. 2013;.
https://hdl.handle.net/21.15107/rcub_nardus_3159 .

Odalović, Marina, "Analiza uticaja životnog stila, socio-ekonomskih faktora i zdravstvenog stanja ispitanica na upotrebu lekova u trudnoći" in Универзитет у Београду (2013),
https://hdl.handle.net/21.15107/rcub_nardus_3159 .

TY  - JOUR
AU  - Odalović, Marina
AU  - Vezmar-Kovačević, Sandra
AU  - Nordeng, Hedvig
AU  - Ilić, Katarina
AU  - Sabo, Ana
AU  - Tasić, Ljiljana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1987
AB  - Background Drug use in pregnancy is often reason of concern for mothers and their physicians. However, only few studies investigated predictors of drug use in pregnancy. Objectives To examine maternal characteristics as predictors of medication use in the 6 months before pregnancy and during the first 6 months of pregnancy. To examine whether prescription and over-the-counter (OTC) medication use in the 6 months before pregnancy had an impact on medication use in pregnancy. Setting Six maternity care units and five community pharmacies. Method Data were collected using a specially designed self-reported questionnaire during the period March 2009-March 2010. Logistic regression was used to identify factors associated with medication use. Main outcome measure Adjusted odds ratios (aOR) and 95 % confidence intervals (CI) were used as association measures. Results A total of 236 women were included in the analysis. After controlling for maternal characteristics, parity of more than one was associated with lower prescription medication use in pregnancy (aOR 0.46; 95 % CI 0.22-0.93), higher household income with higher OTC medication use before pregnancy (aOR 3.13; 95 % CI 1.22-8.00), and miscarriage with higher C and D Food and Drug Administration (FDA) risk category medication use in pregnancy (aOR 3.65; 95 % CI 1.30-10.25). Prescription medication use before pregnancy was associated with higher prescription medication use in pregnancy (aOR 2.49; 95 % CI 1.12-5.52), OTC medication use before pregnancy with higher OTC medication use in pregnancy (aOR 35.95; 95 % CI 7.95-162.49), and C and D FDA risk category medication use before pregnancy with the same category medication use in pregnancy (aOR 3.54; 95 % CI 1.23-10.17). Conclusion Different maternal characteristics were shown as predictors of medication use before and during pregnancy. However, medication use before pregnancy was shown as the most important predicting factor for the medication use in pregnancy.
PB  - Springer, Dordrecht
T2  - International Journal of Clinical Pharmacy
T1  - Predictors of the use of medications before and during pregnancy
VL  - 35
IS  - 3
SP  - 408
EP  - 416
DO  - 10.1007/s11096-013-9750-7
ER  - 

@article{
author = "Odalović, Marina and Vezmar-Kovačević, Sandra and Nordeng, Hedvig and Ilić, Katarina and Sabo, Ana and Tasić, Ljiljana",
year = "2013",
abstract = "Background Drug use in pregnancy is often reason of concern for mothers and their physicians. However, only few studies investigated predictors of drug use in pregnancy. Objectives To examine maternal characteristics as predictors of medication use in the 6 months before pregnancy and during the first 6 months of pregnancy. To examine whether prescription and over-the-counter (OTC) medication use in the 6 months before pregnancy had an impact on medication use in pregnancy. Setting Six maternity care units and five community pharmacies. Method Data were collected using a specially designed self-reported questionnaire during the period March 2009-March 2010. Logistic regression was used to identify factors associated with medication use. Main outcome measure Adjusted odds ratios (aOR) and 95 % confidence intervals (CI) were used as association measures. Results A total of 236 women were included in the analysis. After controlling for maternal characteristics, parity of more than one was associated with lower prescription medication use in pregnancy (aOR 0.46; 95 % CI 0.22-0.93), higher household income with higher OTC medication use before pregnancy (aOR 3.13; 95 % CI 1.22-8.00), and miscarriage with higher C and D Food and Drug Administration (FDA) risk category medication use in pregnancy (aOR 3.65; 95 % CI 1.30-10.25). Prescription medication use before pregnancy was associated with higher prescription medication use in pregnancy (aOR 2.49; 95 % CI 1.12-5.52), OTC medication use before pregnancy with higher OTC medication use in pregnancy (aOR 35.95; 95 % CI 7.95-162.49), and C and D FDA risk category medication use before pregnancy with the same category medication use in pregnancy (aOR 3.54; 95 % CI 1.23-10.17). Conclusion Different maternal characteristics were shown as predictors of medication use before and during pregnancy. However, medication use before pregnancy was shown as the most important predicting factor for the medication use in pregnancy.",
publisher = "Springer, Dordrecht",
journal = "International Journal of Clinical Pharmacy",
title = "Predictors of the use of medications before and during pregnancy",
volume = "35",
number = "3",
pages = "408-416",
doi = "10.1007/s11096-013-9750-7"
}

Odalović, M., Vezmar-Kovačević, S., Nordeng, H., Ilić, K., Sabo, A.,& Tasić, L.. (2013). Predictors of the use of medications before and during pregnancy. in International Journal of Clinical Pharmacy
Springer, Dordrecht., 35(3), 408-416.
https://doi.org/10.1007/s11096-013-9750-7

Odalović M, Vezmar-Kovačević S, Nordeng H, Ilić K, Sabo A, Tasić L. Predictors of the use of medications before and during pregnancy. in International Journal of Clinical Pharmacy. 2013;35(3):408-416.
doi:10.1007/s11096-013-9750-7 .

Odalović, Marina, Vezmar-Kovačević, Sandra, Nordeng, Hedvig, Ilić, Katarina, Sabo, Ana, Tasić, Ljiljana, "Predictors of the use of medications before and during pregnancy" in International Journal of Clinical Pharmacy, 35, no. 3 (2013):408-416,
https://doi.org/10.1007/s11096-013-9750-7 . .

TY  - JOUR
AU  - Odalović, Marina
AU  - Vezmar-Kovačević, Sandra
AU  - Ilić, Katarina
AU  - Sabo, Ana
AU  - Tasić, Ljiljana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1636
AB  - Background Observation of drug use patterns during pregnancy is necessary for the recognition of potential bad practices and improvement of safe drug use in pregnancy. Objective To investigate prescription and over the counter drug use among Serbian women in the 6 months before pregnancy and in the first 6 months of pregnancy, and to evaluate the drugs used according to the risk to a fetus. Setting Six maternity care units and five community pharmacies Method A multi-center study was performed in Serbia during the period from March 2009-March 2010. A self-reporting questionnaire was used as a data source. Food and Drug Administration (FDA) risk classification system was used to determine the risk of used drugs for the fetus. Differences between subgroups were assessed using McNemar's test on paired proportions. Main outcome measure Proportion of women exposed to drugs or class of drugs. Results The overall drug exposure was higher in pregnancy (34.7 %) than before pregnancy (29.9 %), p > 0.05, in the cohort of 311 pregnant women. A significantly greater prescription drug use, 19.0 versus 27.3 % of women, p  lt  0.05, and less selfmedication with over the counter drugs in pregnancy, 15.1 versus 8.7 %, p  lt  0.05, were observed. Commonly used drugs were musculoskeletal drugs, analgesics/antipyretics and respiratory system drugs before pregnancy (13.8, 12.5, and 6.4 % of women, respectively), and progestogens, analgesics/antipyretics, and antibiotics for the systemic use in pregnancy (9.0, 7.7, and 7.4 %, respectively). A greater exposure to drugs belonging to the FDA risk category A (3.9 vs. 60.8 %, p  lt  0.05), B (18.0 vs. 19.6 %, p > 0.05), C (10.0 vs. 10.3 %, p > 0.05) and D (2.9 vs. 10.9 %, p  lt  0.05), as well as less exposure to drugs belonging to category X (0.3 vs. 0 %, p > 0.05) were observed in pregnancy. Folic acid was used by 60.8 % of women in pregnancy, and by only 3.9 % before pregnancy. Conclusion Besides higher overall drug use in pregnancy than before pregnancy, particularly the use of progestogens, and, subsequently, D category drugs, less selfmedication with over the counter drugs was observed in pregnancy. Insufficient use of folic acid before pregnancy requires public health service activities.
PB  - Springer, Dordrecht
T2  - International Journal of Clinical Pharmacy
T1  - Drug use before and during pregnancy in Serbia
VL  - 34
IS  - 5
SP  - 719
EP  - 727
DO  - 10.1007/s11096-012-9665-8
ER  - 

@article{
author = "Odalović, Marina and Vezmar-Kovačević, Sandra and Ilić, Katarina and Sabo, Ana and Tasić, Ljiljana",
year = "2012",
abstract = "Background Observation of drug use patterns during pregnancy is necessary for the recognition of potential bad practices and improvement of safe drug use in pregnancy. Objective To investigate prescription and over the counter drug use among Serbian women in the 6 months before pregnancy and in the first 6 months of pregnancy, and to evaluate the drugs used according to the risk to a fetus. Setting Six maternity care units and five community pharmacies Method A multi-center study was performed in Serbia during the period from March 2009-March 2010. A self-reporting questionnaire was used as a data source. Food and Drug Administration (FDA) risk classification system was used to determine the risk of used drugs for the fetus. Differences between subgroups were assessed using McNemar's test on paired proportions. Main outcome measure Proportion of women exposed to drugs or class of drugs. Results The overall drug exposure was higher in pregnancy (34.7 %) than before pregnancy (29.9 %), p > 0.05, in the cohort of 311 pregnant women. A significantly greater prescription drug use, 19.0 versus 27.3 % of women, p  lt  0.05, and less selfmedication with over the counter drugs in pregnancy, 15.1 versus 8.7 %, p  lt  0.05, were observed. Commonly used drugs were musculoskeletal drugs, analgesics/antipyretics and respiratory system drugs before pregnancy (13.8, 12.5, and 6.4 % of women, respectively), and progestogens, analgesics/antipyretics, and antibiotics for the systemic use in pregnancy (9.0, 7.7, and 7.4 %, respectively). A greater exposure to drugs belonging to the FDA risk category A (3.9 vs. 60.8 %, p  lt  0.05), B (18.0 vs. 19.6 %, p > 0.05), C (10.0 vs. 10.3 %, p > 0.05) and D (2.9 vs. 10.9 %, p  lt  0.05), as well as less exposure to drugs belonging to category X (0.3 vs. 0 %, p > 0.05) were observed in pregnancy. Folic acid was used by 60.8 % of women in pregnancy, and by only 3.9 % before pregnancy. Conclusion Besides higher overall drug use in pregnancy than before pregnancy, particularly the use of progestogens, and, subsequently, D category drugs, less selfmedication with over the counter drugs was observed in pregnancy. Insufficient use of folic acid before pregnancy requires public health service activities.",
publisher = "Springer, Dordrecht",
journal = "International Journal of Clinical Pharmacy",
title = "Drug use before and during pregnancy in Serbia",
volume = "34",
number = "5",
pages = "719-727",
doi = "10.1007/s11096-012-9665-8"
}

Odalović, M., Vezmar-Kovačević, S., Ilić, K., Sabo, A.,& Tasić, L.. (2012). Drug use before and during pregnancy in Serbia. in International Journal of Clinical Pharmacy
Springer, Dordrecht., 34(5), 719-727.
https://doi.org/10.1007/s11096-012-9665-8

Odalović M, Vezmar-Kovačević S, Ilić K, Sabo A, Tasić L. Drug use before and during pregnancy in Serbia. in International Journal of Clinical Pharmacy. 2012;34(5):719-727.
doi:10.1007/s11096-012-9665-8 .

Odalović, Marina, Vezmar-Kovačević, Sandra, Ilić, Katarina, Sabo, Ana, Tasić, Ljiljana, "Drug use before and during pregnancy in Serbia" in International Journal of Clinical Pharmacy, 34, no. 5 (2012):719-727,
https://doi.org/10.1007/s11096-012-9665-8 . .