TY  - JOUR
AU  - Savić, Miroslav
AU  - Kukić-Marković, Jelena
AU  - Grayer, Renee J.
AU  - Milinković, Marija M.
AU  - Marin, Petar
AU  - Divljaković, Jovana
AU  - van Linn, Michael
AU  - Cook, James M.
AU  - Petrović, Silvana
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1336
AB  - We performed a basic behavioral characterization of methanol extracts of four Balkan endemic Stachys taxa: S. anisochila (SA), S. beckeana (SB), S. plumosa (SP) and S. alpina subsp. dinarica (SAD). The behavioral activity of extracts dosed intraperitoneally in the range 100-400 mg/kg was examined in adult male Wistar rats, in the elevated plus maze, spontaneous locomotor activity, and grip strength tests, mainly predictive of anxiolytic, sedative and myorelaxant actions, respectively. All investigated Stachys extracts lacked anxiolytic or myorelaxant activities, while SB at 400 mg/kg exerted an anxiogenic-like effect. The study with the selective antagonist beta-CCt showed that the sedative effect of SAD was only partially mediated by GABAA receptors containing the alpha 1-subunit. While discernible, the behavioral effects of SA and SP were not distinct. In all extracts, chlorogenic acid and verbascoside were identified. In SA, SB, and SAD the flavonoid fraction was constituted of isoscutellarein and hypolaetine glycosides, while in SP chrysoeriol and apigenin glycosides were present. The results reveal the psychotropic potential of four endemic Stachys taxa, of which SAD appeared most promising as a natural sedative. Copyright
PB  - Wiley-Blackwell, Malden
T2  - Phytotherapy Research
T1  - Behavioural Characterization of Four Endemic Stachys Taxa
VL  - 24
IS  - 9
SP  - 1309
EP  - 1316
DO  - 10.1002/ptr.3106
ER  - 

@article{
author = "Savić, Miroslav and Kukić-Marković, Jelena and Grayer, Renee J. and Milinković, Marija M. and Marin, Petar and Divljaković, Jovana and van Linn, Michael and Cook, James M. and Petrović, Silvana",
year = "2010",
abstract = "We performed a basic behavioral characterization of methanol extracts of four Balkan endemic Stachys taxa: S. anisochila (SA), S. beckeana (SB), S. plumosa (SP) and S. alpina subsp. dinarica (SAD). The behavioral activity of extracts dosed intraperitoneally in the range 100-400 mg/kg was examined in adult male Wistar rats, in the elevated plus maze, spontaneous locomotor activity, and grip strength tests, mainly predictive of anxiolytic, sedative and myorelaxant actions, respectively. All investigated Stachys extracts lacked anxiolytic or myorelaxant activities, while SB at 400 mg/kg exerted an anxiogenic-like effect. The study with the selective antagonist beta-CCt showed that the sedative effect of SAD was only partially mediated by GABAA receptors containing the alpha 1-subunit. While discernible, the behavioral effects of SA and SP were not distinct. In all extracts, chlorogenic acid and verbascoside were identified. In SA, SB, and SAD the flavonoid fraction was constituted of isoscutellarein and hypolaetine glycosides, while in SP chrysoeriol and apigenin glycosides were present. The results reveal the psychotropic potential of four endemic Stachys taxa, of which SAD appeared most promising as a natural sedative. Copyright",
publisher = "Wiley-Blackwell, Malden",
journal = "Phytotherapy Research",
title = "Behavioural Characterization of Four Endemic Stachys Taxa",
volume = "24",
number = "9",
pages = "1309-1316",
doi = "10.1002/ptr.3106"
}

Savić, M., Kukić-Marković, J., Grayer, R. J., Milinković, M. M., Marin, P., Divljaković, J., van Linn, M., Cook, J. M.,& Petrović, S.. (2010). Behavioural Characterization of Four Endemic Stachys Taxa. in Phytotherapy Research
Wiley-Blackwell, Malden., 24(9), 1309-1316.
https://doi.org/10.1002/ptr.3106

Savić M, Kukić-Marković J, Grayer RJ, Milinković MM, Marin P, Divljaković J, van Linn M, Cook JM, Petrović S. Behavioural Characterization of Four Endemic Stachys Taxa. in Phytotherapy Research. 2010;24(9):1309-1316.
doi:10.1002/ptr.3106 .

Savić, Miroslav, Kukić-Marković, Jelena, Grayer, Renee J., Milinković, Marija M., Marin, Petar, Divljaković, Jovana, van Linn, Michael, Cook, James M., Petrović, Silvana, "Behavioural Characterization of Four Endemic Stachys Taxa" in Phytotherapy Research, 24, no. 9 (2010):1309-1316,
https://doi.org/10.1002/ptr.3106 . .

TY  - JOUR
AU  - Dajić-Stevanović, Zora
AU  - Šoštarić, Ivan
AU  - Marin, Petar
AU  - Stojanović, Danilo
AU  - Ristić, Mihailo
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1143
AB  - In five indigenous populations of Thymus glabrescens Willd. collected in the region of Banat (Serbia), the variability on leaf morphological traits, leaf and stem anatomy, and composition of the essential oil was studied. The major component in the studied populations was either thymol or γ-terpinene. Distinct differentiation of populations with respect to chemical composition of essential oils might be related to spatial distribution of the studied populations. No correlations between morphology, anatomy, and essential oil yield and composition were determined. Both capitate and peltate glandular trichomes were found on calyces, whereas the latter were noticed on the abaxial and adaxial leaf surface.
AB  - U pet autohtonih populacija Thymus glabrescens Willd. sakupljenih u regionu Banata, Srbija, ispitivana je varijabilnost morfoloških karakteristika lista, anatomske građe lista i stabla i sastava etarskih ulja. Glavne komponente etarskih ulja proučavanih populacija bile su timol, γ-terpinen i p-cimen. Uočena je prostorna diferencijacija populacija u odnosu na sastav etarskih ulja. Nije ustanovljena korelacija između morfoloških i anatomskih karakteristika populacija i prinosa i sastava etarskih ulja. Prisustvo i izgled žlezdanih trihoma su utvrđeni posmatranjem nadzemnih delova na svetlosnom i skening elektronskom mikroskopu. Peltatne trihome su uočene na čašici, licu i naličju lista, dok su kapitatne nađene samo na čašicama.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - Population variability in Thymus glabrescens Willd. from Serbia: Morphology, anatomy and essential oil composition
T1  - Populaciona varijabilnost unutar vrste Thymus glabrescens Willd. iz Srbije - morfologija, anatomija i sastav etarskih ulja
VL  - 60
IS  - 3
SP  - 475
EP  - 483
DO  - 10.2298/ABS0803475D
ER  - 

@article{
author = "Dajić-Stevanović, Zora and Šoštarić, Ivan and Marin, Petar and Stojanović, Danilo and Ristić, Mihailo",
year = "2008",
abstract = "In five indigenous populations of Thymus glabrescens Willd. collected in the region of Banat (Serbia), the variability on leaf morphological traits, leaf and stem anatomy, and composition of the essential oil was studied. The major component in the studied populations was either thymol or γ-terpinene. Distinct differentiation of populations with respect to chemical composition of essential oils might be related to spatial distribution of the studied populations. No correlations between morphology, anatomy, and essential oil yield and composition were determined. Both capitate and peltate glandular trichomes were found on calyces, whereas the latter were noticed on the abaxial and adaxial leaf surface., U pet autohtonih populacija Thymus glabrescens Willd. sakupljenih u regionu Banata, Srbija, ispitivana je varijabilnost morfoloških karakteristika lista, anatomske građe lista i stabla i sastava etarskih ulja. Glavne komponente etarskih ulja proučavanih populacija bile su timol, γ-terpinen i p-cimen. Uočena je prostorna diferencijacija populacija u odnosu na sastav etarskih ulja. Nije ustanovljena korelacija između morfoloških i anatomskih karakteristika populacija i prinosa i sastava etarskih ulja. Prisustvo i izgled žlezdanih trihoma su utvrđeni posmatranjem nadzemnih delova na svetlosnom i skening elektronskom mikroskopu. Peltatne trihome su uočene na čašici, licu i naličju lista, dok su kapitatne nađene samo na čašicama.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Population variability in Thymus glabrescens Willd. from Serbia: Morphology, anatomy and essential oil composition, Populaciona varijabilnost unutar vrste Thymus glabrescens Willd. iz Srbije - morfologija, anatomija i sastav etarskih ulja",
volume = "60",
number = "3",
pages = "475-483",
doi = "10.2298/ABS0803475D"
}

Dajić-Stevanović, Z., Šoštarić, I., Marin, P., Stojanović, D.,& Ristić, M.. (2008). Population variability in Thymus glabrescens Willd. from Serbia: Morphology, anatomy and essential oil composition. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 60(3), 475-483.
https://doi.org/10.2298/ABS0803475D

Dajić-Stevanović Z, Šoštarić I, Marin P, Stojanović D, Ristić M. Population variability in Thymus glabrescens Willd. from Serbia: Morphology, anatomy and essential oil composition. in Archives of Biological Sciences. 2008;60(3):475-483.
doi:10.2298/ABS0803475D .

Dajić-Stevanović, Zora, Šoštarić, Ivan, Marin, Petar, Stojanović, Danilo, Ristić, Mihailo, "Population variability in Thymus glabrescens Willd. from Serbia: Morphology, anatomy and essential oil composition" in Archives of Biological Sciences, 60, no. 3 (2008):475-483,
https://doi.org/10.2298/ABS0803475D . .