TY  - JOUR
AU  - Vučković, Nemanja
AU  - Prlainović, Nevena
AU  - Glođović, Nikola
AU  - Čalija, Bojan
AU  - Milosavljević, Nedeljko
AU  - Kalagasidis Krušić, Melina
AU  - Milašinović, Nikola
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5504
AB  - Novel polymer network microformulations have been widely used for pharmaceutical applications. Especially challenging is to design and develop an ideal oral drug formulation due to many hostile factors in gastrointestinal (GI) tract microenvironment. Hydrogels attained striking attention for the use in controlled drug delivery systems, and for that purpose temperature- and pH-sensitive hydrogels have been extensively employed. This paper reports synthesis and characterization of innovative polymers-crosslinked hydrogel system consisted of N-isopropylacrylamide-graft-dextran (NiPAAm-g-Dex) and chitosan (Ch). Composition of the system was optimized to demonstrate distinguished encapsulation efficiency (EE) and release properties of diclofenac sodium (DS). The microspheres structure and morphology were confirmed by attenuated total reflectance Fourier transform infrared spectroscopy (ATR FT-IR) and scanning electron microscopy (SEM), respectively. Prepared microparticles have successfully passed through the simulated gastric and small intestine and reached the intestine, where the release of DS was carried out. In vitro release studies showed smooth release profile in a controllable manner with up to 40% release of the model drug after 4 h at pH 7.20 ± 0.01. Based on the results, novel polymer microformulations show excellent potential as controlled release drug delivery system and represent a superb candidate for additional in vivo testing.
T2  - Journal of the Iranian Chemical Society
T1  - Novel chitosan and N-isopropylacrylamide-grafted-dextran-based microformulations as effective oral drug delivery system
VL  - 21
IS  - 3
SP  - 781
EP  - 792
DO  - 10.1007/s13738-023-02960-1
ER  - 

@article{
author = "Vučković, Nemanja and Prlainović, Nevena and Glođović, Nikola and Čalija, Bojan and Milosavljević, Nedeljko and Kalagasidis Krušić, Melina and Milašinović, Nikola",
year = "2024",
abstract = "Novel polymer network microformulations have been widely used for pharmaceutical applications. Especially challenging is to design and develop an ideal oral drug formulation due to many hostile factors in gastrointestinal (GI) tract microenvironment. Hydrogels attained striking attention for the use in controlled drug delivery systems, and for that purpose temperature- and pH-sensitive hydrogels have been extensively employed. This paper reports synthesis and characterization of innovative polymers-crosslinked hydrogel system consisted of N-isopropylacrylamide-graft-dextran (NiPAAm-g-Dex) and chitosan (Ch). Composition of the system was optimized to demonstrate distinguished encapsulation efficiency (EE) and release properties of diclofenac sodium (DS). The microspheres structure and morphology were confirmed by attenuated total reflectance Fourier transform infrared spectroscopy (ATR FT-IR) and scanning electron microscopy (SEM), respectively. Prepared microparticles have successfully passed through the simulated gastric and small intestine and reached the intestine, where the release of DS was carried out. In vitro release studies showed smooth release profile in a controllable manner with up to 40% release of the model drug after 4 h at pH 7.20 ± 0.01. Based on the results, novel polymer microformulations show excellent potential as controlled release drug delivery system and represent a superb candidate for additional in vivo testing.",
journal = "Journal of the Iranian Chemical Society",
title = "Novel chitosan and N-isopropylacrylamide-grafted-dextran-based microformulations as effective oral drug delivery system",
volume = "21",
number = "3",
pages = "781-792",
doi = "10.1007/s13738-023-02960-1"
}

Vučković, N., Prlainović, N., Glođović, N., Čalija, B., Milosavljević, N., Kalagasidis Krušić, M.,& Milašinović, N.. (2024). Novel chitosan and N-isopropylacrylamide-grafted-dextran-based microformulations as effective oral drug delivery system. in Journal of the Iranian Chemical Society, 21(3), 781-792.
https://doi.org/10.1007/s13738-023-02960-1

Vučković N, Prlainović N, Glođović N, Čalija B, Milosavljević N, Kalagasidis Krušić M, Milašinović N. Novel chitosan and N-isopropylacrylamide-grafted-dextran-based microformulations as effective oral drug delivery system. in Journal of the Iranian Chemical Society. 2024;21(3):781-792.
doi:10.1007/s13738-023-02960-1 .

Vučković, Nemanja, Prlainović, Nevena, Glođović, Nikola, Čalija, Bojan, Milosavljević, Nedeljko, Kalagasidis Krušić, Melina, Milašinović, Nikola, "Novel chitosan and N-isopropylacrylamide-grafted-dextran-based microformulations as effective oral drug delivery system" in Journal of the Iranian Chemical Society, 21, no. 3 (2024):781-792,
https://doi.org/10.1007/s13738-023-02960-1 . .

TY  - JOUR
AU  - Bogdanović, Mihajlo
AU  - Mladenović, Dragana
AU  - Mojović, Ljiljana
AU  - Đuriš, Jelena
AU  - Đukić-Vuković, Aleksandra
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5558
AB  - The last decade provided significant advances in the understanding of microbiota and its role in human health. Probiotics are live microorganisms with proven benefits for the host and were mostly studied in the context of gut health, but they can also confer significant benefits for oral health, mainly in the treatment of gingivitis. Postbiotics are cell-free extracts and metabolites of microorganisms which can provide additional preventive and therapeutic value for human health. This opens opportunities for new preventive or therapeutic formulations for oral administration. The microorganisms that colonize the oral cavity, their role in oral health and disease, as well as the probiotics and postbiotics which could have beneficial effects in this complex environment were discussed. The aim of this study was to review, analyse and discuss novel probiotic and postbiotic formulations intended for oral administration that could be of great preventive and therapeutic importance. A special attention has been put on the formulation of the pharmaceutical dosage forms that are expected to provide new benefits for the patients and technological advantages relevant for industry. An adequate dosage form could significantly enhance the efficiency of these products.
PB  - Faculdade de Ciencias Farmaceuticas
T2  - Brazilian Journal of Pharmaceutical Sciences
T1  - Intraoral administration of probiotics and postbiotics: An overview of microorganisms and formulation strategies
VL  - 60
DO  - 10.1590/s2175-97902024e23272
ER  - 

@article{
author = "Bogdanović, Mihajlo and Mladenović, Dragana and Mojović, Ljiljana and Đuriš, Jelena and Đukić-Vuković, Aleksandra",
year = "2024",
abstract = "The last decade provided significant advances in the understanding of microbiota and its role in human health. Probiotics are live microorganisms with proven benefits for the host and were mostly studied in the context of gut health, but they can also confer significant benefits for oral health, mainly in the treatment of gingivitis. Postbiotics are cell-free extracts and metabolites of microorganisms which can provide additional preventive and therapeutic value for human health. This opens opportunities for new preventive or therapeutic formulations for oral administration. The microorganisms that colonize the oral cavity, their role in oral health and disease, as well as the probiotics and postbiotics which could have beneficial effects in this complex environment were discussed. The aim of this study was to review, analyse and discuss novel probiotic and postbiotic formulations intended for oral administration that could be of great preventive and therapeutic importance. A special attention has been put on the formulation of the pharmaceutical dosage forms that are expected to provide new benefits for the patients and technological advantages relevant for industry. An adequate dosage form could significantly enhance the efficiency of these products.",
publisher = "Faculdade de Ciencias Farmaceuticas",
journal = "Brazilian Journal of Pharmaceutical Sciences",
title = "Intraoral administration of probiotics and postbiotics: An overview of microorganisms and formulation strategies",
volume = "60",
doi = "10.1590/s2175-97902024e23272"
}

Bogdanović, M., Mladenović, D., Mojović, L., Đuriš, J.,& Đukić-Vuković, A.. (2024). Intraoral administration of probiotics and postbiotics: An overview of microorganisms and formulation strategies. in Brazilian Journal of Pharmaceutical Sciences
Faculdade de Ciencias Farmaceuticas., 60.
https://doi.org/10.1590/s2175-97902024e23272

Bogdanović M, Mladenović D, Mojović L, Đuriš J, Đukić-Vuković A. Intraoral administration of probiotics and postbiotics: An overview of microorganisms and formulation strategies. in Brazilian Journal of Pharmaceutical Sciences. 2024;60.
doi:10.1590/s2175-97902024e23272 .

Bogdanović, Mihajlo, Mladenović, Dragana, Mojović, Ljiljana, Đuriš, Jelena, Đukić-Vuković, Aleksandra, "Intraoral administration of probiotics and postbiotics: An overview of microorganisms and formulation strategies" in Brazilian Journal of Pharmaceutical Sciences, 60 (2024),
https://doi.org/10.1590/s2175-97902024e23272 . .

TY  - JOUR
AU  - Pavun, Leposava
AU  - Spasojević, Danijela
AU  - Ivanovska, Aleksandra
AU  - Lađarević, Jelena
AU  - Milenković, Marina
AU  - Uskoković-Marković, Snežana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5420
AB  - Green, black, rooibos, and hibiscus tea (GT, BT, RT, and HT) aqueous extracts were prepared and
characterized in terms of total flavonoids (TFC) and total phenolic (TPC) contents and antioxidant and
antimicrobial activities. BT has the highest, while HT has the lowest TFC (1213 vs. 415 mg l–1
), while the
extracts’ TPCs (2283 – 7251 mg l–1
) decreased in the following order: BT > GT > RT > HT. Their antioxidant activities of 78.1 – 93.1% and 97.8 – 100% were determined according to DPPH and ABTS methods, respectively. BT and especially GT aqueous extracts possessed mild effects against several microorganisms. All examined extracts have an affinity for dyeing wool, cellulose acetate, polyamide, and cotton,
which is proven by the color strength values of 1.65–19.12. Wool, polyacrylonitrile, polyester, polyamide, cotton, and cellulose acetate functionalized with GT aqueous extract inhibited the growth of S. aureus
and E. coli, while polyacrylonitrile and cotton also inhibited the growth of E. faecalis, and C. albicans,
respectively. Wide inhibition zones for S. aureus were observed for fabrics functionalized with BT aqueous extract. Generally, the investigated fabrics showed very high (81.60 – 100%) ABTS radical scavenging ability independent of the extract used. TPCs have good linear correlations with the antioxidant activities of wool and polyacrylonitrile determined by the DPPH method. Fabrics with different chemical compositions dyed and/or functionalized with GT or BT aqueous extracts can be used to produce high-valueadded medical textiles with therapeutic, prophylactic, and protective functions. They can find potential applications in wound treatment, especially in skin wounds that are susceptible to infection with S. aureus.
Moreover, wool and cotton functionalized with GT or BT aqueous extract can also be considered for use in
disposable medical textiles like bandages and gauze used in the wound-healing process.
Keywords: tea aqueous extract; fabric; functionalization; dyeing; antioxidant and antimicrobial
AB  - Водните екстракти подготвени од црн, зелен, ројбуш и хибискус чај (GT, BT, RT и HT) се
карактеризирани од аспект на количество вкупни флавоноиди (TFC) и вкупни феноли (TPC), и
антиоксидациска и антимикробна активност. BT покажува најголема, а HT најмала TFC (1213 vs.
415 mg l–1), додека TPC во воденте екстракти (2283 – 7251 mg l–1) се намалува според следниов
редослед: BT > GT > RT > HT. Нивната антиоксидациска активност, одредена користејќи ги
методите DPPH и ABTS, се движи соодветно во опсег 78,1 – 93.1 % и 97,8 – 100 %. Водните
екстракти на BT и GT покажаа благ ефект врз одредени микроорганизми. Сите испитувани
екстракти имаат афинитет за боење волна, целулозен ацетат, полиамид и памук, што е потврдено
со одредување на јачина на бојата на ткаенините која изнесува 1,65 – 19.12. Волната,
полиакрилонитрилот, полиестерот, полиамидот, памукот и целулозниот ацетат функционализирани со воден екстракт од GT го инхибираат растот на S. aureus и E. coli, додека
полиакрилонитрилот и памукот соодветно го инхибираат растот на E. faecalis и C. albicans.
Широки инхибициони зони за S. aureus се воочени за ткаенините функционализирани со BT.
Општо, испитуваните ткаенини покажуваат многу висока (81,60 – 100 %) способност за
отстранување на ABTS-радикали. Утврдена е добра линеарна зависност помеѓу TPC во водните
екстракти и антиоксидациската активност на волната и полиакрилонитрилот одредени преку
методот DPPH. Ткаенините со различен хемиски состав обоени и/или функционализирани со
водни екстракти од GT или BT можат да се користат за производство на медицински текстил со
висока додадена вредност, кој има терапевтски, профилактички и заштитни функции.
Медицинските текстилни материјали имаат потенцијална примена за третман на рани, особено за
рани на кожа кои се подложни на инфекција со S. aureus. Покрај тоа, волната и памукот
функционализирани со водни екстракти од GT или BT можат да се користат за производство на
медицински завои и гази за еднократна употреба.
PB  - Macedonian Journal of Chemistry and Chemical Engineering
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions
T1  - Карактеризација на водни екстракти од чаеви и нивна употреба за боење и функционализација на ткаенини со различен хемиски состав
VL  - 42
IS  - 2
SP  - 263
EP  - 273
DO  - 10.20450/mjcce2023.2698
ER  - 

@article{
author = "Pavun, Leposava and Spasojević, Danijela and Ivanovska, Aleksandra and Lađarević, Jelena and Milenković, Marina and Uskoković-Marković, Snežana",
year = "2023",
abstract = "Green, black, rooibos, and hibiscus tea (GT, BT, RT, and HT) aqueous extracts were prepared and
characterized in terms of total flavonoids (TFC) and total phenolic (TPC) contents and antioxidant and
antimicrobial activities. BT has the highest, while HT has the lowest TFC (1213 vs. 415 mg l–1
), while the
extracts’ TPCs (2283 – 7251 mg l–1
) decreased in the following order: BT > GT > RT > HT. Their antioxidant activities of 78.1 – 93.1% and 97.8 – 100% were determined according to DPPH and ABTS methods, respectively. BT and especially GT aqueous extracts possessed mild effects against several microorganisms. All examined extracts have an affinity for dyeing wool, cellulose acetate, polyamide, and cotton,
which is proven by the color strength values of 1.65–19.12. Wool, polyacrylonitrile, polyester, polyamide, cotton, and cellulose acetate functionalized with GT aqueous extract inhibited the growth of S. aureus
and E. coli, while polyacrylonitrile and cotton also inhibited the growth of E. faecalis, and C. albicans,
respectively. Wide inhibition zones for S. aureus were observed for fabrics functionalized with BT aqueous extract. Generally, the investigated fabrics showed very high (81.60 – 100%) ABTS radical scavenging ability independent of the extract used. TPCs have good linear correlations with the antioxidant activities of wool and polyacrylonitrile determined by the DPPH method. Fabrics with different chemical compositions dyed and/or functionalized with GT or BT aqueous extracts can be used to produce high-valueadded medical textiles with therapeutic, prophylactic, and protective functions. They can find potential applications in wound treatment, especially in skin wounds that are susceptible to infection with S. aureus.
Moreover, wool and cotton functionalized with GT or BT aqueous extract can also be considered for use in
disposable medical textiles like bandages and gauze used in the wound-healing process.
Keywords: tea aqueous extract; fabric; functionalization; dyeing; antioxidant and antimicrobial, Водните екстракти подготвени од црн, зелен, ројбуш и хибискус чај (GT, BT, RT и HT) се
карактеризирани од аспект на количество вкупни флавоноиди (TFC) и вкупни феноли (TPC), и
антиоксидациска и антимикробна активност. BT покажува најголема, а HT најмала TFC (1213 vs.
415 mg l–1), додека TPC во воденте екстракти (2283 – 7251 mg l–1) се намалува според следниов
редослед: BT > GT > RT > HT. Нивната антиоксидациска активност, одредена користејќи ги
методите DPPH и ABTS, се движи соодветно во опсег 78,1 – 93.1 % и 97,8 – 100 %. Водните
екстракти на BT и GT покажаа благ ефект врз одредени микроорганизми. Сите испитувани
екстракти имаат афинитет за боење волна, целулозен ацетат, полиамид и памук, што е потврдено
со одредување на јачина на бојата на ткаенините која изнесува 1,65 – 19.12. Волната,
полиакрилонитрилот, полиестерот, полиамидот, памукот и целулозниот ацетат функционализирани со воден екстракт од GT го инхибираат растот на S. aureus и E. coli, додека
полиакрилонитрилот и памукот соодветно го инхибираат растот на E. faecalis и C. albicans.
Широки инхибициони зони за S. aureus се воочени за ткаенините функционализирани со BT.
Општо, испитуваните ткаенини покажуваат многу висока (81,60 – 100 %) способност за
отстранување на ABTS-радикали. Утврдена е добра линеарна зависност помеѓу TPC во водните
екстракти и антиоксидациската активност на волната и полиакрилонитрилот одредени преку
методот DPPH. Ткаенините со различен хемиски состав обоени и/или функционализирани со
водни екстракти од GT или BT можат да се користат за производство на медицински текстил со
висока додадена вредност, кој има терапевтски, профилактички и заштитни функции.
Медицинските текстилни материјали имаат потенцијална примена за третман на рани, особено за
рани на кожа кои се подложни на инфекција со S. aureus. Покрај тоа, волната и памукот
функционализирани со водни екстракти од GT или BT можат да се користат за производство на
медицински завои и гази за еднократна употреба.",
publisher = "Macedonian Journal of Chemistry and Chemical Engineering",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions, Карактеризација на водни екстракти од чаеви и нивна употреба за боење и функционализација на ткаенини со различен хемиски состав",
volume = "42",
number = "2",
pages = "263-273",
doi = "10.20450/mjcce2023.2698"
}

Pavun, L., Spasojević, D., Ivanovska, A., Lađarević, J., Milenković, M.,& Uskoković-Marković, S.. (2023). Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions. in Macedonian Journal of Chemistry and Chemical Engineering
Macedonian Journal of Chemistry and Chemical Engineering., 42(2), 263-273.
https://doi.org/10.20450/mjcce2023.2698

Pavun L, Spasojević D, Ivanovska A, Lađarević J, Milenković M, Uskoković-Marković S. Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions. in Macedonian Journal of Chemistry and Chemical Engineering. 2023;42(2):263-273.
doi:10.20450/mjcce2023.2698 .

Pavun, Leposava, Spasojević, Danijela, Ivanovska, Aleksandra, Lađarević, Jelena, Milenković, Marina, Uskoković-Marković, Snežana, "Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions" in Macedonian Journal of Chemistry and Chemical Engineering, 42, no. 2 (2023):263-273,
https://doi.org/10.20450/mjcce2023.2698 . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Lađarević, Jelena
AU  - Asanović, Koviljka
AU  - Pavun, Leposava
AU  - Kostić, Mirjana
AU  - Mangovska, Biljana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4475
AB  - The present paper demonstrates a simple way for revalorization of differently softened cotton and cotton/elastane knitted fabric waste collected from the textile industry. Such waste was used as an adsorbent for Congo Red (CR) dye, whereby up to 96% removal efficiency was reached. The CR adsorption process onto cationic and silicone softened fabrics is in conformity with Langmuir (with maximum adsorption capacity of 12.533 mg/g) and Freundlich isotherms, respectively. Different adsorption of CR onto cationic and silicone softened fabrics is ascribed to the different softeners’ fixation to them, while the adsorption of CR operates in the same manner, via hydrophobic interactions. The adsorption kinetic data follow the pseudo-second-order model, while the equilibrium was reached after 90 min. Additionally, this study proposed a new circular economy solution for the disposal of fabric waste with adsorbed CR generating additional revenues. The volume electrical resistivity measurements confirmed that the knitted fabric wastes with adsorbed CR have 169–737 times lower resistivities (0.008–0.037 GΩ·cm) than before the adsorption. The inversely proportional correlation between fabrics’ adsorption efficiencies and their volume electrical resistivities after CR adsorption was found. Such knitted fabric waste with adsorbed CR could be defined as dissipative materials and could be used for providing antistatic protection.
PB  - Springer
T2  - Fibers and Polymers
T1  - Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste
VL  - 24
IS  - 2
SP  - 749
EP  - 758
DO  - 10.1007/s12221-023-00045-7
ER  - 

@article{
author = "Ivanovska, Aleksandra and Lađarević, Jelena and Asanović, Koviljka and Pavun, Leposava and Kostić, Mirjana and Mangovska, Biljana",
year = "2023",
abstract = "The present paper demonstrates a simple way for revalorization of differently softened cotton and cotton/elastane knitted fabric waste collected from the textile industry. Such waste was used as an adsorbent for Congo Red (CR) dye, whereby up to 96% removal efficiency was reached. The CR adsorption process onto cationic and silicone softened fabrics is in conformity with Langmuir (with maximum adsorption capacity of 12.533 mg/g) and Freundlich isotherms, respectively. Different adsorption of CR onto cationic and silicone softened fabrics is ascribed to the different softeners’ fixation to them, while the adsorption of CR operates in the same manner, via hydrophobic interactions. The adsorption kinetic data follow the pseudo-second-order model, while the equilibrium was reached after 90 min. Additionally, this study proposed a new circular economy solution for the disposal of fabric waste with adsorbed CR generating additional revenues. The volume electrical resistivity measurements confirmed that the knitted fabric wastes with adsorbed CR have 169–737 times lower resistivities (0.008–0.037 GΩ·cm) than before the adsorption. The inversely proportional correlation between fabrics’ adsorption efficiencies and their volume electrical resistivities after CR adsorption was found. Such knitted fabric waste with adsorbed CR could be defined as dissipative materials and could be used for providing antistatic protection.",
publisher = "Springer",
journal = "Fibers and Polymers",
title = "Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste",
volume = "24",
number = "2",
pages = "749-758",
doi = "10.1007/s12221-023-00045-7"
}

Ivanovska, A., Lađarević, J., Asanović, K., Pavun, L., Kostić, M.,& Mangovska, B.. (2023). Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste. in Fibers and Polymers
Springer., 24(2), 749-758.
https://doi.org/10.1007/s12221-023-00045-7

Ivanovska A, Lađarević J, Asanović K, Pavun L, Kostić M, Mangovska B. Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste. in Fibers and Polymers. 2023;24(2):749-758.
doi:10.1007/s12221-023-00045-7 .

Ivanovska, Aleksandra, Lađarević, Jelena, Asanović, Koviljka, Pavun, Leposava, Kostić, Mirjana, Mangovska, Biljana, "Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste" in Fibers and Polymers, 24, no. 2 (2023):749-758,
https://doi.org/10.1007/s12221-023-00045-7 . .

TY  - CONF
AU  - Čutović, Natalija
AU  - Jovanović, Aleksandra
AU  - Rajab Elferjane, Rajab Elferjane
AU  - Milutinović, Violeta
AU  - Petrović, Predrag
AU  - Marinković, Aleksandar
AU  - Bugarski, Branko
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5261
AB  - Aloe vera (L.) Burm. f. (Asphodelaceae) contains anthraquinones, their glycosides, flavonoids, 
tannins, terpenoids, saponins, resins, mono- and polysaccharides, polypeptides, lectins, enzymes, 
vitamins, and minerals. The plant is used in traditional medicine due to its antitumor, 
antioxidant, anti-inflammatory, antiulcerogenic, immunomodulatory, analgesic, and dermal 
protection properties. Maceration and heat-assisted extraction (HAE) are frequently used 
extraction procedures because of their simple operation and low costs. In the present study, A. 
vera dried leaves were extracted using ethanol (50%, V/V; drug solvent ratio 1:30, w/V). The 
influence of different extraction times (30-120 min for maceration and 15-60 min for HAE), and 
various extraction temperatures (40, 60, and 80ºC) in HAE on the total polyphenol content 
(TPC) and radical scavenging potential (ABTS and DPPH methods) was evaluated, while for the 
most prominent extracts (with the highest TPC) zeta potential and conductivity were additionally 
analyzed. Regarding maceration, the TPC was correlated with the rise in extraction time up to 
45 min (from 7.8±0.72 to 9.66±0.51 mg gallic acid equivalents (GAE)/g of plant material) and 
after that reached the steady state (~9.1 mg GAE/g). In HAE, no statistically significant 
differences between the TPC of the extracts obtained after 15, 30, and 45 min (9.77±0.32, 
9.76±0.18, and 9.95±0.50 mg GAE/g) were observed, while the extract prepared after 60 min 
showed significantly lower TPC (8.14±0.08 mg GAE/g). The TPC was in correlation with the 
increase of extraction temperatures (9.08±0.21 at 40ºC, 9.38±0.10 at 60ºC, and 9.86±0.24 mg 
GAE/g at 80ºC). As in the case of TPC results, anti-ABTS activity was significantly different 
between 30 and 45 min of maceration and reached the steady state after 45 min (~2.01 mmol 
Trolox/g of plant material). In HAE, the anti-ABTS potential of the extracts obtained at different 
extraction times was comparable (1.44-1.64 mmol Trolox/g), whereas the activity of the extract 
obtained at 40ºC was lower. DPPH radical scavenging activity rose after 45 min of maceration 
when also reached the steady state (~40.4 mg/mL), but there were no significant differences 
between the extracts prepared at different extraction times in HAE, and IC50 was lower for the 
extract obtained at 80ºC. Hence, the macerate prepared after 45 min and HAE extract obtained 
after 15 min at 80ºC exhibited very low zeta potential (0.14±0.06 and 0.50±0.01 mV), and 
conductivity (1.05±0.07 and 0.98±0.01 mS/cm). This study was an initial step in the production of A. vera polyphenol extracts aimed to be used for the formulation of foodstuffs, medicines, and 
cosmetics.
PB  - University of East Sarajevo, Faculty of technology
C3  - VIII International Congress “Engineering, Environment and Materials in Process Industry-EEM2023", Jahorina, March 20-23, 2023, Republic of Srpska, Bosnia and Herzegovina, Proceedings
T1  - Maceration and heat-assisted extraction of polyphenols from Aloe vera
SP  - 136
EP  - 143
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5261
ER  - 

@conference{
author = "Čutović, Natalija and Jovanović, Aleksandra and Rajab Elferjane, Rajab Elferjane and Milutinović, Violeta and Petrović, Predrag and Marinković, Aleksandar and Bugarski, Branko",
year = "2023",
abstract = "Aloe vera (L.) Burm. f. (Asphodelaceae) contains anthraquinones, their glycosides, flavonoids, 
tannins, terpenoids, saponins, resins, mono- and polysaccharides, polypeptides, lectins, enzymes, 
vitamins, and minerals. The plant is used in traditional medicine due to its antitumor, 
antioxidant, anti-inflammatory, antiulcerogenic, immunomodulatory, analgesic, and dermal 
protection properties. Maceration and heat-assisted extraction (HAE) are frequently used 
extraction procedures because of their simple operation and low costs. In the present study, A. 
vera dried leaves were extracted using ethanol (50%, V/V; drug solvent ratio 1:30, w/V). The 
influence of different extraction times (30-120 min for maceration and 15-60 min for HAE), and 
various extraction temperatures (40, 60, and 80ºC) in HAE on the total polyphenol content 
(TPC) and radical scavenging potential (ABTS and DPPH methods) was evaluated, while for the 
most prominent extracts (with the highest TPC) zeta potential and conductivity were additionally 
analyzed. Regarding maceration, the TPC was correlated with the rise in extraction time up to 
45 min (from 7.8±0.72 to 9.66±0.51 mg gallic acid equivalents (GAE)/g of plant material) and 
after that reached the steady state (~9.1 mg GAE/g). In HAE, no statistically significant 
differences between the TPC of the extracts obtained after 15, 30, and 45 min (9.77±0.32, 
9.76±0.18, and 9.95±0.50 mg GAE/g) were observed, while the extract prepared after 60 min 
showed significantly lower TPC (8.14±0.08 mg GAE/g). The TPC was in correlation with the 
increase of extraction temperatures (9.08±0.21 at 40ºC, 9.38±0.10 at 60ºC, and 9.86±0.24 mg 
GAE/g at 80ºC). As in the case of TPC results, anti-ABTS activity was significantly different 
between 30 and 45 min of maceration and reached the steady state after 45 min (~2.01 mmol 
Trolox/g of plant material). In HAE, the anti-ABTS potential of the extracts obtained at different 
extraction times was comparable (1.44-1.64 mmol Trolox/g), whereas the activity of the extract 
obtained at 40ºC was lower. DPPH radical scavenging activity rose after 45 min of maceration 
when also reached the steady state (~40.4 mg/mL), but there were no significant differences 
between the extracts prepared at different extraction times in HAE, and IC50 was lower for the 
extract obtained at 80ºC. Hence, the macerate prepared after 45 min and HAE extract obtained 
after 15 min at 80ºC exhibited very low zeta potential (0.14±0.06 and 0.50±0.01 mV), and 
conductivity (1.05±0.07 and 0.98±0.01 mS/cm). This study was an initial step in the production of A. vera polyphenol extracts aimed to be used for the formulation of foodstuffs, medicines, and 
cosmetics.",
publisher = "University of East Sarajevo, Faculty of technology",
journal = "VIII International Congress “Engineering, Environment and Materials in Process Industry-EEM2023", Jahorina, March 20-23, 2023, Republic of Srpska, Bosnia and Herzegovina, Proceedings",
title = "Maceration and heat-assisted extraction of polyphenols from Aloe vera",
pages = "136-143",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5261"
}

Čutović, N., Jovanović, A., Rajab Elferjane, R. E., Milutinović, V., Petrović, P., Marinković, A.,& Bugarski, B.. (2023). Maceration and heat-assisted extraction of polyphenols from Aloe vera. in VIII International Congress “Engineering, Environment and Materials in Process Industry-EEM2023", Jahorina, March 20-23, 2023, Republic of Srpska, Bosnia and Herzegovina, Proceedings
University of East Sarajevo, Faculty of technology., 136-143.
https://hdl.handle.net/21.15107/rcub_farfar_5261

Čutović N, Jovanović A, Rajab Elferjane RE, Milutinović V, Petrović P, Marinković A, Bugarski B. Maceration and heat-assisted extraction of polyphenols from Aloe vera. in VIII International Congress “Engineering, Environment and Materials in Process Industry-EEM2023", Jahorina, March 20-23, 2023, Republic of Srpska, Bosnia and Herzegovina, Proceedings. 2023;:136-143.
https://hdl.handle.net/21.15107/rcub_farfar_5261 .

Čutović, Natalija, Jovanović, Aleksandra, Rajab Elferjane, Rajab Elferjane, Milutinović, Violeta, Petrović, Predrag, Marinković, Aleksandar, Bugarski, Branko, "Maceration and heat-assisted extraction of polyphenols from Aloe vera" in VIII International Congress “Engineering, Environment and Materials in Process Industry-EEM2023", Jahorina, March 20-23, 2023, Republic of Srpska, Bosnia and Herzegovina, Proceedings (2023):136-143,
https://hdl.handle.net/21.15107/rcub_farfar_5261 .

TY  - JOUR
AU  - Rajab Elferjane, Muna
AU  - Jovanović, Aleksandra A.
AU  - Milutinović, Violeta
AU  - Čutović, Natalija
AU  - Jovanović Krivokuća, Milica
AU  - Marinković, Aleksandar
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4956
AB  - In the study, the optimization of the extraction from Aloe vera leaf waste was performed via varying solid-to-solvent ratio, solvent type, extraction time, and technique (maceration, heat-, ultrasound-, and microwave-assisted extractions—HAE, UAE, and MAE, respectively). The optimal extraction conditions for achieving the highest polyphenol content are a 1:30 ratio, 70% ethanol, and 30 min of HAE. Total flavonoid and protein contents were significantly higher in the extract from MAE, while total condensed tannin content was the highest in HAE. LC-MS analysis quantified 13 anthraquinone and chromone compounds. The variations in the FT-IR spectra of the extracts obtained by different extraction procedures are minor. The influence of extraction conditions on the antioxidant ability of the extracts depended on applied antioxidant assays. The extracts possessed medium inhibition properties against Staphylococcus aureus and weak inhibitory activity against Enterococcus feacalis. The extracts had stimulative effect on HaCaT cell viability. Regarding the extraction yield, there was a significant difference between the used extraction techniques (MAE > HAE > maceration and UAE). The presented study is an initial step in the production of polyphenol-rich extracts from A. vera leaf waste aimed to be used for the potential preparation of pharmaceutical and cosmetic formulations for the skin.
PB  - MDPI
T2  - Plants
T1  - From Aloe vera Leaf Waste to the Extracts with Biological Potential: Optimization of the Extractions, Physicochemical Characterization, and Biological Activities
VL  - 12
IS  - 14
DO  - 10.3390/plants12142744
ER  - 

@article{
author = "Rajab Elferjane, Muna and Jovanović, Aleksandra A. and Milutinović, Violeta and Čutović, Natalija and Jovanović Krivokuća, Milica and Marinković, Aleksandar",
year = "2023",
abstract = "In the study, the optimization of the extraction from Aloe vera leaf waste was performed via varying solid-to-solvent ratio, solvent type, extraction time, and technique (maceration, heat-, ultrasound-, and microwave-assisted extractions—HAE, UAE, and MAE, respectively). The optimal extraction conditions for achieving the highest polyphenol content are a 1:30 ratio, 70% ethanol, and 30 min of HAE. Total flavonoid and protein contents were significantly higher in the extract from MAE, while total condensed tannin content was the highest in HAE. LC-MS analysis quantified 13 anthraquinone and chromone compounds. The variations in the FT-IR spectra of the extracts obtained by different extraction procedures are minor. The influence of extraction conditions on the antioxidant ability of the extracts depended on applied antioxidant assays. The extracts possessed medium inhibition properties against Staphylococcus aureus and weak inhibitory activity against Enterococcus feacalis. The extracts had stimulative effect on HaCaT cell viability. Regarding the extraction yield, there was a significant difference between the used extraction techniques (MAE > HAE > maceration and UAE). The presented study is an initial step in the production of polyphenol-rich extracts from A. vera leaf waste aimed to be used for the potential preparation of pharmaceutical and cosmetic formulations for the skin.",
publisher = "MDPI",
journal = "Plants",
title = "From Aloe vera Leaf Waste to the Extracts with Biological Potential: Optimization of the Extractions, Physicochemical Characterization, and Biological Activities",
volume = "12",
number = "14",
doi = "10.3390/plants12142744"
}

Rajab Elferjane, M., Jovanović, A. A., Milutinović, V., Čutović, N., Jovanović Krivokuća, M.,& Marinković, A.. (2023). From Aloe vera Leaf Waste to the Extracts with Biological Potential: Optimization of the Extractions, Physicochemical Characterization, and Biological Activities. in Plants
MDPI., 12(14).
https://doi.org/10.3390/plants12142744

Rajab Elferjane M, Jovanović AA, Milutinović V, Čutović N, Jovanović Krivokuća M, Marinković A. From Aloe vera Leaf Waste to the Extracts with Biological Potential: Optimization of the Extractions, Physicochemical Characterization, and Biological Activities. in Plants. 2023;12(14).
doi:10.3390/plants12142744 .

Rajab Elferjane, Muna, Jovanović, Aleksandra A., Milutinović, Violeta, Čutović, Natalija, Jovanović Krivokuća, Milica, Marinković, Aleksandar, "From Aloe vera Leaf Waste to the Extracts with Biological Potential: Optimization of the Extractions, Physicochemical Characterization, and Biological Activities" in Plants, 12, no. 14 (2023),
https://doi.org/10.3390/plants12142744 . .

TY  - JOUR
AU  - Krmar, Jovana
AU  - Tolić Stojadinović, Ljiljana
AU  - Đurkić, Tatjana
AU  - Protić, Ana
AU  - Otašević, Biljana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4881
AB  - A priori estimation of analyte response is crucial for the efficient development of liquid chromatography–electrospray ionization/mass spectrometry (LC–ESI/MS) methods, but remains a demanding task given the lack of knowledge about the factors affecting the experimental outcome. In this research, we address the challenge of discovering the interactive relationship between signal response and structural properties, method parameters and solvent-related descriptors throughout an approach featuring quantitative structure–property relationship (QSPR) and design of experiments (DoE). To systematically investigate the experimental domain within which QSPR prediction should be undertaken, we varied LC and instrumental factors according to the Box-Behnken DoE scheme. Seven compounds, including aripiprazole and its impurities, were subjected to 57 different experimental conditions, resulting in 399 LC–ESI/MS data endpoints. To obtain a more standard distribution of the measured response, the peak areas were log-transformed before modeling. QSPR predictions were made using features selected by Genetic Algorithm (GA) and providing Gradient Boosted Trees (GBT) with training data. Proposed model showed satisfactory performance on test data with a RMSEP of 1.57 % and a of 96.48 %. This is the first QSPR study in LC–ESI/MS that provided a holistic overview of the analyte’s response behavior across the experimental and chemical space. Since intramolecular electronic effects and molecular size were given great importance, the GA–GBT model improved the understanding of signal response generation of model compounds. It also highlighted the need to fine-tune the parameters affecting desolvation and droplet charging efficiency.
PB  - Elsevier Inc.
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Predicting liquid chromatography−electrospray ionization/mass spectrometry signal from the structure of model compounds and experimental factors; case study of aripiprazole and its impurities
VL  - 233
DO  - 10.1016/j.jpba.2023.115422
ER  - 

@article{
author = "Krmar, Jovana and Tolić Stojadinović, Ljiljana and Đurkić, Tatjana and Protić, Ana and Otašević, Biljana",
year = "2023",
abstract = "A priori estimation of analyte response is crucial for the efficient development of liquid chromatography–electrospray ionization/mass spectrometry (LC–ESI/MS) methods, but remains a demanding task given the lack of knowledge about the factors affecting the experimental outcome. In this research, we address the challenge of discovering the interactive relationship between signal response and structural properties, method parameters and solvent-related descriptors throughout an approach featuring quantitative structure–property relationship (QSPR) and design of experiments (DoE). To systematically investigate the experimental domain within which QSPR prediction should be undertaken, we varied LC and instrumental factors according to the Box-Behnken DoE scheme. Seven compounds, including aripiprazole and its impurities, were subjected to 57 different experimental conditions, resulting in 399 LC–ESI/MS data endpoints. To obtain a more standard distribution of the measured response, the peak areas were log-transformed before modeling. QSPR predictions were made using features selected by Genetic Algorithm (GA) and providing Gradient Boosted Trees (GBT) with training data. Proposed model showed satisfactory performance on test data with a RMSEP of 1.57 % and a of 96.48 %. This is the first QSPR study in LC–ESI/MS that provided a holistic overview of the analyte’s response behavior across the experimental and chemical space. Since intramolecular electronic effects and molecular size were given great importance, the GA–GBT model improved the understanding of signal response generation of model compounds. It also highlighted the need to fine-tune the parameters affecting desolvation and droplet charging efficiency.",
publisher = "Elsevier Inc.",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Predicting liquid chromatography−electrospray ionization/mass spectrometry signal from the structure of model compounds and experimental factors; case study of aripiprazole and its impurities",
volume = "233",
doi = "10.1016/j.jpba.2023.115422"
}

Krmar, J., Tolić Stojadinović, L., Đurkić, T., Protić, A.,& Otašević, B.. (2023). Predicting liquid chromatography−electrospray ionization/mass spectrometry signal from the structure of model compounds and experimental factors; case study of aripiprazole and its impurities. in Journal of Pharmaceutical and Biomedical Analysis
Elsevier Inc.., 233.
https://doi.org/10.1016/j.jpba.2023.115422

Krmar J, Tolić Stojadinović L, Đurkić T, Protić A, Otašević B. Predicting liquid chromatography−electrospray ionization/mass spectrometry signal from the structure of model compounds and experimental factors; case study of aripiprazole and its impurities. in Journal of Pharmaceutical and Biomedical Analysis. 2023;233.
doi:10.1016/j.jpba.2023.115422 .

Krmar, Jovana, Tolić Stojadinović, Ljiljana, Đurkić, Tatjana, Protić, Ana, Otašević, Biljana, "Predicting liquid chromatography−electrospray ionization/mass spectrometry signal from the structure of model compounds and experimental factors; case study of aripiprazole and its impurities" in Journal of Pharmaceutical and Biomedical Analysis, 233 (2023),
https://doi.org/10.1016/j.jpba.2023.115422 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Bakić, Tamara
AU  - Topić, Aleksandra
AU  - Lukić, Jelena
AU  - Onjia, Antonije
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4549
AB  - A fast and straightforward reversed-phase dispersive liquid–liquid microextraction (RP-DLLME) using a deep eutectic solvent (DES) procedure to determine free tryptophan in vegetable oils was developed. The influence of eight variables affecting the RP-DLLME efficiency has been studied by a multivariate approach. A Plackett–Burman design for screening the most influential variables followed by a central composite response surface methodology led to an optimum RP-DLLME setup for a 1 g oil sample: 9 mL hexane as the diluting solvent, vortex extraction with 0.45 mL of DES (choline chloride–urea) at 40 °C, without addition of salt, and centrifugation at 6000 rpm for 4.0 min. The reconstituted extract was directly injected into a high-performance liquid chromatography (HPLC) system working in the diode array mode. At the studied concentration levels, the obtained method detection limits (MDL) was 11 mg/kg, linearity in matrix-matched standards was R2 ≥ 0.997, relative standard deviations (RSD) was 7.8%, and average recovery was 93%. The combined use of the recently developed DES -based RP-DLLME and HPLC provides an innovative, efficient, cost-effective, and more sustainable method for the extraction and quantification of free tryptophan in oily food matrices. The method was employed to analyze cold-pressed oils from nine vegetables (Brazil nut, almond, cashew, hazelnut, peanut, pumpkin, sesame, sunflower, and walnut) for the first time. The results showed that free tryptophan was present in the range of 11–38 mg/100 g. This article is important for its contributions to the field of food analysis, and for its development of a new and efficient method for the determination of free tryptophan in complex matrices, which has the potential to be applied to other analytes and sample types.
PB  - MDPI
T2  - Molecules
T1  - Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils
VL  - 28
IS  - 5
DO  - 10.3390/molecules28052395
ER  - 

@article{
author = "Ražić, Slavica and Bakić, Tamara and Topić, Aleksandra and Lukić, Jelena and Onjia, Antonije",
year = "2023",
abstract = "A fast and straightforward reversed-phase dispersive liquid–liquid microextraction (RP-DLLME) using a deep eutectic solvent (DES) procedure to determine free tryptophan in vegetable oils was developed. The influence of eight variables affecting the RP-DLLME efficiency has been studied by a multivariate approach. A Plackett–Burman design for screening the most influential variables followed by a central composite response surface methodology led to an optimum RP-DLLME setup for a 1 g oil sample: 9 mL hexane as the diluting solvent, vortex extraction with 0.45 mL of DES (choline chloride–urea) at 40 °C, without addition of salt, and centrifugation at 6000 rpm for 4.0 min. The reconstituted extract was directly injected into a high-performance liquid chromatography (HPLC) system working in the diode array mode. At the studied concentration levels, the obtained method detection limits (MDL) was 11 mg/kg, linearity in matrix-matched standards was R2 ≥ 0.997, relative standard deviations (RSD) was 7.8%, and average recovery was 93%. The combined use of the recently developed DES -based RP-DLLME and HPLC provides an innovative, efficient, cost-effective, and more sustainable method for the extraction and quantification of free tryptophan in oily food matrices. The method was employed to analyze cold-pressed oils from nine vegetables (Brazil nut, almond, cashew, hazelnut, peanut, pumpkin, sesame, sunflower, and walnut) for the first time. The results showed that free tryptophan was present in the range of 11–38 mg/100 g. This article is important for its contributions to the field of food analysis, and for its development of a new and efficient method for the determination of free tryptophan in complex matrices, which has the potential to be applied to other analytes and sample types.",
publisher = "MDPI",
journal = "Molecules",
title = "Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils",
volume = "28",
number = "5",
doi = "10.3390/molecules28052395"
}

Ražić, S., Bakić, T., Topić, A., Lukić, J.,& Onjia, A.. (2023). Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils. in Molecules
MDPI., 28(5).
https://doi.org/10.3390/molecules28052395

Ražić S, Bakić T, Topić A, Lukić J, Onjia A. Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils. in Molecules. 2023;28(5).
doi:10.3390/molecules28052395 .

Ražić, Slavica, Bakić, Tamara, Topić, Aleksandra, Lukić, Jelena, Onjia, Antonije, "Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils" in Molecules, 28, no. 5 (2023),
https://doi.org/10.3390/molecules28052395 . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Dojčinović, Biljana
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Mijin, Dušan
AU  - Kostić, Mirjana
AU  - Svetozarević, Milica
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4519
AB  - This study is aimed at extending the soybean hulls' lifetime by their utilization as an adsorbent for metal ions (Cd2+ and Cu2+) and dyes (Reactive Yellow 39 (RY 39) and Acid Blue 225 (AB 225)). ATR-FTIR spectroscopy, FE-SEM microscopy, and zeta potential measurements were used for adsorbent characterization. The effect of the solution's pH, peroxidase extraction, adsorbent particle size, contact time, the pollutant's initial concentration, and temperature on the soybean hulls' adsorption potential was studied. Before peroxidase extraction, soybean hulls were capable of removing 72% Cd2+, 71% Cu2+ (at a pH of 5.00) or 81% RY 39, and 73% AB 225 (at a pH of 3.00). For further experiments, soybean hulls without peroxidase were used for several reasons: (1) due to their observed higher metal ion removal, (2) in order to reduce the waste disposal cost after the peroxidase (usually used for wastewater decolorization) extraction, and (3) since the soybean hulls without peroxidase possessed significantly lower secondary pollution than those with peroxidase. Cd2+ and Cu2+ removal was slightly increased when the smaller adsorbent fraction (710-1000 μm) was used, while the adsorbent particle size did not have an impact on dye removal. After 30 min of contact time, 92% and 88% of RY 39 and AB 225 were removed, respectively, while after the same contact time, 80% and 69% of Cd2+ and Cu2+ were removed, respectively. Adsorption of all tested pollutants follows a pseudo-second-order reaction through the fast adsorption, intraparticle diffusion, and final equilibrium stage. The maximal adsorption capacities determined by the Langmuir model were 21.10, 20.54, 16.54, and 17.23 mg/g for Cd2+, Cu2+, RY 39, and AB 225, respectively. Calculated thermodynamic parameters suggested that the adsorption of all pollutants is spontaneous and of endothermic character. Moreover, different binary mixtures were prepared, and the competitive adsorptions revealed that the soybean hulls are the most efficient adsorbent for the mixture of AB 225 and Cu2+. The findings of this study contribute to the soybean hulls' recovery after the peroxidase extraction and bring them into the circular economy concept.
PB  - Hindawi
T2  - Adsorption Science and Technology
T1  - Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes
VL  - 2023
DO  - 10.1155/2023/8532316
ER  - 

@article{
author = "Ivanovska, Aleksandra and Dojčinović, Biljana and Lađarević, Jelena and Pavun, Leposava and Mijin, Dušan and Kostić, Mirjana and Svetozarević, Milica",
year = "2023",
abstract = "This study is aimed at extending the soybean hulls' lifetime by their utilization as an adsorbent for metal ions (Cd2+ and Cu2+) and dyes (Reactive Yellow 39 (RY 39) and Acid Blue 225 (AB 225)). ATR-FTIR spectroscopy, FE-SEM microscopy, and zeta potential measurements were used for adsorbent characterization. The effect of the solution's pH, peroxidase extraction, adsorbent particle size, contact time, the pollutant's initial concentration, and temperature on the soybean hulls' adsorption potential was studied. Before peroxidase extraction, soybean hulls were capable of removing 72% Cd2+, 71% Cu2+ (at a pH of 5.00) or 81% RY 39, and 73% AB 225 (at a pH of 3.00). For further experiments, soybean hulls without peroxidase were used for several reasons: (1) due to their observed higher metal ion removal, (2) in order to reduce the waste disposal cost after the peroxidase (usually used for wastewater decolorization) extraction, and (3) since the soybean hulls without peroxidase possessed significantly lower secondary pollution than those with peroxidase. Cd2+ and Cu2+ removal was slightly increased when the smaller adsorbent fraction (710-1000 μm) was used, while the adsorbent particle size did not have an impact on dye removal. After 30 min of contact time, 92% and 88% of RY 39 and AB 225 were removed, respectively, while after the same contact time, 80% and 69% of Cd2+ and Cu2+ were removed, respectively. Adsorption of all tested pollutants follows a pseudo-second-order reaction through the fast adsorption, intraparticle diffusion, and final equilibrium stage. The maximal adsorption capacities determined by the Langmuir model were 21.10, 20.54, 16.54, and 17.23 mg/g for Cd2+, Cu2+, RY 39, and AB 225, respectively. Calculated thermodynamic parameters suggested that the adsorption of all pollutants is spontaneous and of endothermic character. Moreover, different binary mixtures were prepared, and the competitive adsorptions revealed that the soybean hulls are the most efficient adsorbent for the mixture of AB 225 and Cu2+. The findings of this study contribute to the soybean hulls' recovery after the peroxidase extraction and bring them into the circular economy concept.",
publisher = "Hindawi",
journal = "Adsorption Science and Technology",
title = "Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes",
volume = "2023",
doi = "10.1155/2023/8532316"
}

Ivanovska, A., Dojčinović, B., Lađarević, J., Pavun, L., Mijin, D., Kostić, M.,& Svetozarević, M.. (2023). Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes. in Adsorption Science and Technology
Hindawi., 2023.
https://doi.org/10.1155/2023/8532316

Ivanovska A, Dojčinović B, Lađarević J, Pavun L, Mijin D, Kostić M, Svetozarević M. Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes. in Adsorption Science and Technology. 2023;2023.
doi:10.1155/2023/8532316 .

Ivanovska, Aleksandra, Dojčinović, Biljana, Lađarević, Jelena, Pavun, Leposava, Mijin, Dušan, Kostić, Mirjana, Svetozarević, Milica, "Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes" in Adsorption Science and Technology, 2023 (2023),
https://doi.org/10.1155/2023/8532316 . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Milošević, Marija
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Svirčev, Zorica
AU  - Kostić, Mirjana
AU  - Meriluoto, Juss
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4514
AB  - Featured Application: This work has a potential application in biocarpet engineering, which involves the use of cyanobacterial crusts either in the rehabilitation of damaged land surfaces or to combat desertification. Attempts to apply cyanobacterial crusts have not been completely successful so far because the growth of the initial inoculum requires more moisture than arid and semiarid environments can provide. To accelerate the development of the inoculum, it is necessary to provide additional moisture for the growth of cyanobacterial cells. Controlled water delivery could be achieved by using moisture-retentive material that is applied together with the inoculum in the treatment of damaged surfaces. Biocarpet engineering has the potential to solve not only some problems of damaged surfaces and desertification but also reduce and prevent air and water pollution caused by erosion. Raw jute fabric was treated with 0.5, 1.0, or 2.0% chitosan solution to improve its sorption properties (evaluated through the moisture sorption and adsorption of textile dye Reactive Orange 16 (RO 16)), which are essential for fabric utilization as geo-prebiotic polysaccharide support that should provide the necessary water for the growth of cyanobacterial communities in biocarpet engineering. Chitosan-treated fabrics possessed 39–78% higher moisture sorption values than the untreated ones. Concerning the dye adsorption, with the increase in its initial concentration, the adsorption potential of raw and fabrics treated with 0.5 or 1.0% chitosan solution was increased up to 1.9 times. The dye adsorption onto these fabrics was exothermic and enthalpy driven. By increasing the chitosan solution percentage up to 1.0%, fabric adsorption potential increased up to 2.2 times. An inverse relationship was observed in the case of the fabric treated with 2.0% chitosan solution, its adsorption potential decreased with increasing the initial dye concentration and temperature due to the different dominant binding interactions. Concerning the contact time, dye adsorption onto fabric treated with 1.0% chitosan solution was rapid in the first 2 h, while the equilibrium was attained after 4.5 h. The isotherm and kinetic data were represented by the Langmuir model and the pseudo-second-order kinetic model, respectively.
PB  - MDPI
T2  - Applied Sciences
T1  - Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties
VL  - 13
IS  - 4
DO  - 10.3390/app13042512
ER  - 

@article{
author = "Ivanovska, Aleksandra and Milošević, Marija and Lađarević, Jelena and Pavun, Leposava and Svirčev, Zorica and Kostić, Mirjana and Meriluoto, Juss",
year = "2023",
abstract = "Featured Application: This work has a potential application in biocarpet engineering, which involves the use of cyanobacterial crusts either in the rehabilitation of damaged land surfaces or to combat desertification. Attempts to apply cyanobacterial crusts have not been completely successful so far because the growth of the initial inoculum requires more moisture than arid and semiarid environments can provide. To accelerate the development of the inoculum, it is necessary to provide additional moisture for the growth of cyanobacterial cells. Controlled water delivery could be achieved by using moisture-retentive material that is applied together with the inoculum in the treatment of damaged surfaces. Biocarpet engineering has the potential to solve not only some problems of damaged surfaces and desertification but also reduce and prevent air and water pollution caused by erosion. Raw jute fabric was treated with 0.5, 1.0, or 2.0% chitosan solution to improve its sorption properties (evaluated through the moisture sorption and adsorption of textile dye Reactive Orange 16 (RO 16)), which are essential for fabric utilization as geo-prebiotic polysaccharide support that should provide the necessary water for the growth of cyanobacterial communities in biocarpet engineering. Chitosan-treated fabrics possessed 39–78% higher moisture sorption values than the untreated ones. Concerning the dye adsorption, with the increase in its initial concentration, the adsorption potential of raw and fabrics treated with 0.5 or 1.0% chitosan solution was increased up to 1.9 times. The dye adsorption onto these fabrics was exothermic and enthalpy driven. By increasing the chitosan solution percentage up to 1.0%, fabric adsorption potential increased up to 2.2 times. An inverse relationship was observed in the case of the fabric treated with 2.0% chitosan solution, its adsorption potential decreased with increasing the initial dye concentration and temperature due to the different dominant binding interactions. Concerning the contact time, dye adsorption onto fabric treated with 1.0% chitosan solution was rapid in the first 2 h, while the equilibrium was attained after 4.5 h. The isotherm and kinetic data were represented by the Langmuir model and the pseudo-second-order kinetic model, respectively.",
publisher = "MDPI",
journal = "Applied Sciences",
title = "Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties",
volume = "13",
number = "4",
doi = "10.3390/app13042512"
}

Ivanovska, A., Milošević, M., Lađarević, J., Pavun, L., Svirčev, Z., Kostić, M.,& Meriluoto, J.. (2023). Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties. in Applied Sciences
MDPI., 13(4).
https://doi.org/10.3390/app13042512

Ivanovska A, Milošević M, Lađarević J, Pavun L, Svirčev Z, Kostić M, Meriluoto J. Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties. in Applied Sciences. 2023;13(4).
doi:10.3390/app13042512 .

Ivanovska, Aleksandra, Milošević, Marija, Lađarević, Jelena, Pavun, Leposava, Svirčev, Zorica, Kostić, Mirjana, Meriluoto, Juss, "Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties" in Applied Sciences, 13, no. 4 (2023),
https://doi.org/10.3390/app13042512 . .

TY  - CONF
AU  - Ivanovska, Aleksandra
AU  - Milenković, Jovana
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Kostić, Mirjana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5234
AB  - Abstract
Green tea aqueous extract was prepared and characterized regarding total flavonoids and total
phenolic contents as well as antioxidant activity (assessed by ABTS method). The characterized
aqueous extract was used for dyeing and functionalization of 100% cotton and cotton/linen
(47%/53% and 70%/30%) fabrics. Fabric color strength (K/S) values and their antioxidant
activities before and after washing were compared. The obtained results revealed that 100%
cotton (GTI), 47%/53% cotton/linen (GTII), and 70%/30% cotton/linen (GTIII) fabrics have
K/S values ranging between 8.33 and 10.85. After one washing cycle, these values decreased
significantly. On the other hand, dyed fabrics showed excellent (100 %) ABTS radical
scavenging ability which remained excellent (GTII) or decreased to medium (GTI and GTIII)
levels after one washing cycle. Based on the obtained results, it can be concluded that 47%/53%
cotton/linen fabric is the most suitable for functional clothing capable of trapping the free radial
of oxygen species. The current paper represents a step towards a more sustainable textile
industry that could undoubtedly contribute to overcoming the environmental problems caused
by the textile industry
PB  - University of Szeged, Hungary
C3  - 29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings
T1  - Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract
SP  - 163
EP  - 166
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5234
ER  - 

@conference{
author = "Ivanovska, Aleksandra and Milenković, Jovana and Lađarević, Jelena and Pavun, Leposava and Kostić, Mirjana",
year = "2023",
abstract = "Abstract
Green tea aqueous extract was prepared and characterized regarding total flavonoids and total
phenolic contents as well as antioxidant activity (assessed by ABTS method). The characterized
aqueous extract was used for dyeing and functionalization of 100% cotton and cotton/linen
(47%/53% and 70%/30%) fabrics. Fabric color strength (K/S) values and their antioxidant
activities before and after washing were compared. The obtained results revealed that 100%
cotton (GTI), 47%/53% cotton/linen (GTII), and 70%/30% cotton/linen (GTIII) fabrics have
K/S values ranging between 8.33 and 10.85. After one washing cycle, these values decreased
significantly. On the other hand, dyed fabrics showed excellent (100 %) ABTS radical
scavenging ability which remained excellent (GTII) or decreased to medium (GTI and GTIII)
levels after one washing cycle. Based on the obtained results, it can be concluded that 47%/53%
cotton/linen fabric is the most suitable for functional clothing capable of trapping the free radial
of oxygen species. The current paper represents a step towards a more sustainable textile
industry that could undoubtedly contribute to overcoming the environmental problems caused
by the textile industry",
publisher = "University of Szeged, Hungary",
journal = "29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings",
title = "Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract",
pages = "163-166",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5234"
}

Ivanovska, A., Milenković, J., Lađarević, J., Pavun, L.,& Kostić, M.. (2023). Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract. in 29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings
University of Szeged, Hungary., 163-166.
https://hdl.handle.net/21.15107/rcub_farfar_5234

Ivanovska A, Milenković J, Lađarević J, Pavun L, Kostić M. Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract. in 29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings. 2023;:163-166.
https://hdl.handle.net/21.15107/rcub_farfar_5234 .

Ivanovska, Aleksandra, Milenković, Jovana, Lađarević, Jelena, Pavun, Leposava, Kostić, Mirjana, "Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract" in 29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings (2023):163-166,
https://hdl.handle.net/21.15107/rcub_farfar_5234 .

TY  - DATA
AU  - Krmar, Jovana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4883
AB  - Dataset for mixed QSPR modeling.
The response modeling procedure, which simultaneously considered method parameters, solvent-related descriptors, and structural properties of the analytes, required organizing data into a matrix. The X matrix (Table A.1) refers to the (J × K) LC–ESI(+)/MS data collected for a set of analytes under different working conditions. The total number of rows (J) corresponds to the total number of endpoints (measurements performed). It refers to the number of rows (N) of the Box-Behnken (BBD) experimental matrix that are repeated over C analytes. The rows of the (N x S) BBD matrix show all possible combinations of settings for the factors represented in the columns S. The X matrix comprised a total of K columns, with S columns corresponding to experimental factors, P columns representing solvent-related properties, M columns representing molecular descriptors, and one L column corresponding to response-dependent variable. For the C compounds considered in our study, the molecular descriptors make up a (C x M) Q matrix. Repeated application of the BBD matrix over the C compounds augmented property matrix Q.
PB  - University of Belgrade - Faculty of Pharmacy
T2  - Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms
T1  - Supplementary material for doctoral dissertation: Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4883
ER  - 

@misc{
author = "Krmar, Jovana",
year = "2023",
abstract = "Dataset for mixed QSPR modeling.
The response modeling procedure, which simultaneously considered method parameters, solvent-related descriptors, and structural properties of the analytes, required organizing data into a matrix. The X matrix (Table A.1) refers to the (J × K) LC–ESI(+)/MS data collected for a set of analytes under different working conditions. The total number of rows (J) corresponds to the total number of endpoints (measurements performed). It refers to the number of rows (N) of the Box-Behnken (BBD) experimental matrix that are repeated over C analytes. The rows of the (N x S) BBD matrix show all possible combinations of settings for the factors represented in the columns S. The X matrix comprised a total of K columns, with S columns corresponding to experimental factors, P columns representing solvent-related properties, M columns representing molecular descriptors, and one L column corresponding to response-dependent variable. For the C compounds considered in our study, the molecular descriptors make up a (C x M) Q matrix. Repeated application of the BBD matrix over the C compounds augmented property matrix Q.",
publisher = "University of Belgrade - Faculty of Pharmacy",
journal = "Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms",
title = "Supplementary material for doctoral dissertation: Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4883"
}

Krmar, J.. (2023). Supplementary material for doctoral dissertation: Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms. in Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms
University of Belgrade - Faculty of Pharmacy..
https://hdl.handle.net/21.15107/rcub_farfar_4883

Krmar J. Supplementary material for doctoral dissertation: Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms. in Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms. 2023;.
https://hdl.handle.net/21.15107/rcub_farfar_4883 .

Krmar, Jovana, "Supplementary material for doctoral dissertation: Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms" in Prediction of Retention and Ionization Behavior of Selected Analytes in Micellar Liquid Chromatography and Mass Spectrometry Using Machine Learning Algorithms (2023),
https://hdl.handle.net/21.15107/rcub_farfar_4883 .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Veljović, Sonja
AU  - Reljić, Mirjana
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Natić, Maja
AU  - Kostić, Mirjana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5059
AB  - ABSTRACT
This study reports the successful transformation of mulberry wood waste
into natural textile dye and adsorbent for Pb2+ ions from an aqueous solution. Fabrics of different chemical compositions were dyed using mulberry
wood extract, whereas wool possessed the best appearance and color fastness to washing. Among differently dyed wool fabrics, those dyed with 15%
extract for 5 h has the highest color strength (K/S = 11.24) and antioxidant
activity (83.5%), and the best color and antioxidant activity fastness to
washing, making it appropriate for protecting the skin from diverse damages
by decelerating the effect of free radical. Moreover, it could be suggested
that the binding mechanism proceeds via strong hydrogen bonds between
wool surface carboxylate groups and characteristic phenolics found in the
extract (dominantly taxifolin, oxyresveratrol, ellagic acid, and tannins). The
mulberry wood solid parts separated after the extraction were further evaluated as adsorbents for Pb2+ ions. The highest lead removal was achieved at
a solution pH of 5.5, while the equilibrium removal was reached after 4 h of
contact time. At 20 mg/l initial lead concentration, the mulberry wood waste
removal efficiency was 98.8%. The results of this study represent a step
forward to a healthier, cleaner, and more sustainable society
AB  - 摘要
本研究报告了将桑木废料成功转化为天然纺织染料和水溶液中Pb2+ 离子
的吸附剂. 不同化学成分的织物用桑木提取物染色, 而羊毛的外观和耐洗色
牢度最好. 在不同染色的羊毛织物中, 用15%提取物染色5小时的羊毛织物
具有最高的颜色强度 (K/S = 11.24) 和抗氧化活性 (83.5%), 并且具有最佳的
颜色和抗氧化活性耐洗牢度, 因此适合通过减缓自由基的作用来保护皮肤
免受各种损伤. 此外, 可以认为, 结合机制是通过羊毛表面羧基和提取物中
的特征酚类 (主要是紫杉醇, 白藜芦醇, 鞣花酸和单宁) 之间的强氢键进行
的. 提取后分离的桑木固体部分被进一步评估为Pb2+ 离子的吸附剂. 在溶
液pH值为5.5时, 铅的去除率最高, 而接触时间为4小时后, 铅的去除率达到
平衡. 在20mg/l的初始铅浓度下, 桑木废弃物的去除率为98.8%. 这项研究的
结果代表着朝着一个更健康, 更清洁, 更可持续的社会迈进了一步.
PB  - Taylor & Francis
T2  - Journal of Natural Fibers
T1  - Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste
VL  - 19
IS  - 15
SP  - 11050
EP  - 11063
DO  - 10.1080/15440478.2021.2009398
ER  - 

@article{
author = "Ivanovska, Aleksandra and Veljović, Sonja and Reljić, Mirjana and Lađarević, Jelena and Pavun, Leposava and Natić, Maja and Kostić, Mirjana",
year = "2022",
abstract = "ABSTRACT
This study reports the successful transformation of mulberry wood waste
into natural textile dye and adsorbent for Pb2+ ions from an aqueous solution. Fabrics of different chemical compositions were dyed using mulberry
wood extract, whereas wool possessed the best appearance and color fastness to washing. Among differently dyed wool fabrics, those dyed with 15%
extract for 5 h has the highest color strength (K/S = 11.24) and antioxidant
activity (83.5%), and the best color and antioxidant activity fastness to
washing, making it appropriate for protecting the skin from diverse damages
by decelerating the effect of free radical. Moreover, it could be suggested
that the binding mechanism proceeds via strong hydrogen bonds between
wool surface carboxylate groups and characteristic phenolics found in the
extract (dominantly taxifolin, oxyresveratrol, ellagic acid, and tannins). The
mulberry wood solid parts separated after the extraction were further evaluated as adsorbents for Pb2+ ions. The highest lead removal was achieved at
a solution pH of 5.5, while the equilibrium removal was reached after 4 h of
contact time. At 20 mg/l initial lead concentration, the mulberry wood waste
removal efficiency was 98.8%. The results of this study represent a step
forward to a healthier, cleaner, and more sustainable society, 摘要
本研究报告了将桑木废料成功转化为天然纺织染料和水溶液中Pb2+ 离子
的吸附剂. 不同化学成分的织物用桑木提取物染色, 而羊毛的外观和耐洗色
牢度最好. 在不同染色的羊毛织物中, 用15%提取物染色5小时的羊毛织物
具有最高的颜色强度 (K/S = 11.24) 和抗氧化活性 (83.5%), 并且具有最佳的
颜色和抗氧化活性耐洗牢度, 因此适合通过减缓自由基的作用来保护皮肤
免受各种损伤. 此外, 可以认为, 结合机制是通过羊毛表面羧基和提取物中
的特征酚类 (主要是紫杉醇, 白藜芦醇, 鞣花酸和单宁) 之间的强氢键进行
的. 提取后分离的桑木固体部分被进一步评估为Pb2+ 离子的吸附剂. 在溶
液pH值为5.5时, 铅的去除率最高, 而接触时间为4小时后, 铅的去除率达到
平衡. 在20mg/l的初始铅浓度下, 桑木废弃物的去除率为98.8%. 这项研究的
结果代表着朝着一个更健康, 更清洁, 更可持续的社会迈进了一步.",
publisher = "Taylor & Francis",
journal = "Journal of Natural Fibers",
title = "Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste",
volume = "19",
number = "15",
pages = "11050-11063",
doi = "10.1080/15440478.2021.2009398"
}

Ivanovska, A., Veljović, S., Reljić, M., Lađarević, J., Pavun, L., Natić, M.,& Kostić, M.. (2022). Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste. in Journal of Natural Fibers
Taylor & Francis., 19(15), 11050-11063.
https://doi.org/10.1080/15440478.2021.2009398

Ivanovska A, Veljović S, Reljić M, Lađarević J, Pavun L, Natić M, Kostić M. Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste. in Journal of Natural Fibers. 2022;19(15):11050-11063.
doi:10.1080/15440478.2021.2009398 .

Ivanovska, Aleksandra, Veljović, Sonja, Reljić, Mirjana, Lađarević, Jelena, Pavun, Leposava, Natić, Maja, Kostić, Mirjana, "Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste" in Journal of Natural Fibers, 19, no. 15 (2022):11050-11063,
https://doi.org/10.1080/15440478.2021.2009398 . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Branković, Ivana
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Kostić, Mirjana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5060
AB  - The raw jute fabric was oxidized with 0.2% or 0.4% NaIO4 for 60 or 120 min to obtain valuable adsorbents for the
textile dye Congo Red (CR). Batch adsorption experiments were carried out as a function of solution pH, contact
time, initial CR concentration, and temperature. At an initial CR concentration of 25 mg/L, the raw jute possessed the
lowest adsorption due to the lowest availability and content of carboxyl and aldehyde groups capable of binding dye. The
fabrics oxidized for 60 min with 0.2% NaIO4 and 120 min with 0.4% NaIO4 reached equilibrium adsorption after 240 and
330 min, respectively. The adsorption of CR onto studied fabrics followed the pseudo-second-order model indicating
that the chemisorption process is primarily represented. Within the studied range of CR concentrations (25–100 mg/L),
its adsorption onto fabric oxidized for 120 min with 0.4% NaIO4 obeys the Langmuir isotherm model (i.e. adsorption
occurs at specific, energetically equivalent adsorbent sites with monolayer coverage of CR over a homogeneous surface),
wherein the calculated maximal adsorption capacity is 12.863 mg/g. A thermodynamic study revealed the spontaneous
and endothermic character of CR adsorption onto jute fabric. Based on the recorded ATR-FTIR spectra before and after
CR adsorption, it is suggested that repulsion, hydrogen bonds, and π-π stacking interactions are involved in the binding
of CR onto jute fabrics.
PB  - Sage Journals
T2  - Journal of Engineered Fibers and Fabrics
T1  - Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution
VL  - 17
DO  - 10.1177/15589250221101380
ER  - 

@article{
author = "Ivanovska, Aleksandra and Branković, Ivana and Lađarević, Jelena and Pavun, Leposava and Kostić, Mirjana",
year = "2022",
abstract = "The raw jute fabric was oxidized with 0.2% or 0.4% NaIO4 for 60 or 120 min to obtain valuable adsorbents for the
textile dye Congo Red (CR). Batch adsorption experiments were carried out as a function of solution pH, contact
time, initial CR concentration, and temperature. At an initial CR concentration of 25 mg/L, the raw jute possessed the
lowest adsorption due to the lowest availability and content of carboxyl and aldehyde groups capable of binding dye. The
fabrics oxidized for 60 min with 0.2% NaIO4 and 120 min with 0.4% NaIO4 reached equilibrium adsorption after 240 and
330 min, respectively. The adsorption of CR onto studied fabrics followed the pseudo-second-order model indicating
that the chemisorption process is primarily represented. Within the studied range of CR concentrations (25–100 mg/L),
its adsorption onto fabric oxidized for 120 min with 0.4% NaIO4 obeys the Langmuir isotherm model (i.e. adsorption
occurs at specific, energetically equivalent adsorbent sites with monolayer coverage of CR over a homogeneous surface),
wherein the calculated maximal adsorption capacity is 12.863 mg/g. A thermodynamic study revealed the spontaneous
and endothermic character of CR adsorption onto jute fabric. Based on the recorded ATR-FTIR spectra before and after
CR adsorption, it is suggested that repulsion, hydrogen bonds, and π-π stacking interactions are involved in the binding
of CR onto jute fabrics.",
publisher = "Sage Journals",
journal = "Journal of Engineered Fibers and Fabrics",
title = "Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution",
volume = "17",
doi = "10.1177/15589250221101380"
}

Ivanovska, A., Branković, I., Lađarević, J., Pavun, L.,& Kostić, M.. (2022). Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution. in Journal of Engineered Fibers and Fabrics
Sage Journals., 17.
https://doi.org/10.1177/15589250221101380

Ivanovska A, Branković I, Lađarević J, Pavun L, Kostić M. Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution. in Journal of Engineered Fibers and Fabrics. 2022;17.
doi:10.1177/15589250221101380 .

Ivanovska, Aleksandra, Branković, Ivana, Lađarević, Jelena, Pavun, Leposava, Kostić, Mirjana, "Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution" in Journal of Engineered Fibers and Fabrics, 17 (2022),
https://doi.org/10.1177/15589250221101380 . .

TY  - JOUR
AU  - Božić, Bojan
AU  - Lađarević, Jelena
AU  - Petković, Miloš
AU  - Mijin, Dušan
AU  - Stavber, Stojan
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4433
AB  - The susceptibility of the carbonyl group towards nucleophilic attack affords the construction of various organic compounds. Thus, investigations of carbonyl activation applying greener methodologies are highly important. In the present work, among the investigated N-halo compounds, N-fluorobenzenesulfonimide (NFSi) has been found as an efficient and selective catalyst in the reaction of direct esterification of aryl and alkyl carboxylic acids supported by microwave (MW) irradiation. The comprehensive esterification of different benzoic acids and mono-, di-and tri-carboxy alkyl derivatives was performed, whereby significant reaction time reductions were achieved. The presented method used NFSi as an easily manipulatable, non-metal, water-and air-tolerant catalyst, allowing simple synthetic and isolation procedures and energy saving, compared to conventional methodologies. Importantly, in contrast to esterification under thermal conditions, where N-halo compounds behave as pre-catalysts, in the MW-supported protocol, a distinct reaction mechanism has been proposed that assumes NFSi as a sustainable catalyst. Moreover, a scale-up of the industrially important derivative was performed.
PB  - MDPI
T2  - Catalysts
T1  - Microwave Assisted Esterification of Aryl/Alkyl Acids Catalyzed by N-Fluorobenzenesulfonimide
VL  - 12
IS  - 11
DO  - 10.3390/catal12111413
ER  - 

@article{
author = "Božić, Bojan and Lađarević, Jelena and Petković, Miloš and Mijin, Dušan and Stavber, Stojan",
year = "2022",
abstract = "The susceptibility of the carbonyl group towards nucleophilic attack affords the construction of various organic compounds. Thus, investigations of carbonyl activation applying greener methodologies are highly important. In the present work, among the investigated N-halo compounds, N-fluorobenzenesulfonimide (NFSi) has been found as an efficient and selective catalyst in the reaction of direct esterification of aryl and alkyl carboxylic acids supported by microwave (MW) irradiation. The comprehensive esterification of different benzoic acids and mono-, di-and tri-carboxy alkyl derivatives was performed, whereby significant reaction time reductions were achieved. The presented method used NFSi as an easily manipulatable, non-metal, water-and air-tolerant catalyst, allowing simple synthetic and isolation procedures and energy saving, compared to conventional methodologies. Importantly, in contrast to esterification under thermal conditions, where N-halo compounds behave as pre-catalysts, in the MW-supported protocol, a distinct reaction mechanism has been proposed that assumes NFSi as a sustainable catalyst. Moreover, a scale-up of the industrially important derivative was performed.",
publisher = "MDPI",
journal = "Catalysts",
title = "Microwave Assisted Esterification of Aryl/Alkyl Acids Catalyzed by N-Fluorobenzenesulfonimide",
volume = "12",
number = "11",
doi = "10.3390/catal12111413"
}

Božić, B., Lađarević, J., Petković, M., Mijin, D.,& Stavber, S.. (2022). Microwave Assisted Esterification of Aryl/Alkyl Acids Catalyzed by N-Fluorobenzenesulfonimide. in Catalysts
MDPI., 12(11).
https://doi.org/10.3390/catal12111413

Božić B, Lađarević J, Petković M, Mijin D, Stavber S. Microwave Assisted Esterification of Aryl/Alkyl Acids Catalyzed by N-Fluorobenzenesulfonimide. in Catalysts. 2022;12(11).
doi:10.3390/catal12111413 .

Božić, Bojan, Lađarević, Jelena, Petković, Miloš, Mijin, Dušan, Stavber, Stojan, "Microwave Assisted Esterification of Aryl/Alkyl Acids Catalyzed by N-Fluorobenzenesulfonimide" in Catalysts, 12, no. 11 (2022),
https://doi.org/10.3390/catal12111413 . .

TY  - JOUR
AU  - Jovanović, Marija
AU  - Petrović, Miloš
AU  - Stojanović, Dušica
AU  - Ibrić, Svetlana
AU  - Uskoković, Petar
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4410
AB  - In this work, a blend of gelatin A (GA) and polyvinylpyrrolidone (PVP K30) was used for
semi-solid 3D printing of bone scaffold for ibuprofen (IBU) delivery. The cross-linking of the
obtained scaffold was performed with a 1% glutaraldehyde (GTA) solution, followed by
lyophilization. The thermal and mechanical properties, as well as drug release profiles, and drug
kinetics of prepared scaffolds were investigated. The cross-linked and lyophilized scaffold has
shown good thermal stability, mechanical properties, and prolonged release of IBU following the
Fickian diffusion process.
AB  - Nosač za dostavu ibuprofena (IBU) u koštanom tkivu dobijen je metodom 3D štampe ekstruzijom iz paste uz korišćenje smeše polimera želatina A (GA) i polivinilpirolidona (PVP K30). Dobijeni nosač je umrežen sa 1% rastvorom glutaraldehida (GTA), nakon čega je usledio proces liofilizacije uzoraka. Ispitivana su mehanička i termička svojstva, profili i kinetika oslobađanja ibuprofena iz dobijenih nosača. Umrežen i liofilizovan nosač pokazao je dobru termičku stabilnost i mehanička svojstva, kao i produženo oslobađanje IBU-a koje prati kinetiku po Fikovom zakonu difuzije.
PB  - Pharmaceutical Association of Serbia
T2  - Arhiv za farmaciju
T1  - Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery
T1  - 3D štampa i karakterizacija nosača za dostavu ibuprofena u koštanom tkivu
VL  - 72
IS  - 6
SP  - 661
EP  - 673
DO  - 10.5937/arhfarm72-40262
ER  - 

@article{
author = "Jovanović, Marija and Petrović, Miloš and Stojanović, Dušica and Ibrić, Svetlana and Uskoković, Petar",
year = "2022",
abstract = "In this work, a blend of gelatin A (GA) and polyvinylpyrrolidone (PVP K30) was used for
semi-solid 3D printing of bone scaffold for ibuprofen (IBU) delivery. The cross-linking of the
obtained scaffold was performed with a 1% glutaraldehyde (GTA) solution, followed by
lyophilization. The thermal and mechanical properties, as well as drug release profiles, and drug
kinetics of prepared scaffolds were investigated. The cross-linked and lyophilized scaffold has
shown good thermal stability, mechanical properties, and prolonged release of IBU following the
Fickian diffusion process., Nosač za dostavu ibuprofena (IBU) u koštanom tkivu dobijen je metodom 3D štampe ekstruzijom iz paste uz korišćenje smeše polimera želatina A (GA) i polivinilpirolidona (PVP K30). Dobijeni nosač je umrežen sa 1% rastvorom glutaraldehida (GTA), nakon čega je usledio proces liofilizacije uzoraka. Ispitivana su mehanička i termička svojstva, profili i kinetika oslobađanja ibuprofena iz dobijenih nosača. Umrežen i liofilizovan nosač pokazao je dobru termičku stabilnost i mehanička svojstva, kao i produženo oslobađanje IBU-a koje prati kinetiku po Fikovom zakonu difuzije.",
publisher = "Pharmaceutical Association of Serbia",
journal = "Arhiv za farmaciju",
title = "Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery, 3D štampa i karakterizacija nosača za dostavu ibuprofena u koštanom tkivu",
volume = "72",
number = "6",
pages = "661-673",
doi = "10.5937/arhfarm72-40262"
}

Jovanović, M., Petrović, M., Stojanović, D., Ibrić, S.,& Uskoković, P.. (2022). Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery. in Arhiv za farmaciju
Pharmaceutical Association of Serbia., 72(6), 661-673.
https://doi.org/10.5937/arhfarm72-40262

Jovanović M, Petrović M, Stojanović D, Ibrić S, Uskoković P. Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery. in Arhiv za farmaciju. 2022;72(6):661-673.
doi:10.5937/arhfarm72-40262 .

Jovanović, Marija, Petrović, Miloš, Stojanović, Dušica, Ibrić, Svetlana, Uskoković, Petar, "Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery" in Arhiv za farmaciju, 72, no. 6 (2022):661-673,
https://doi.org/10.5937/arhfarm72-40262 . .

TY  - CONF
AU  - Filipovć, Vladimir
AU  - Ugrenović, Vladan
AU  - Maksimović, Zoran
AU  - Dimitrijević, Snežana
AU  - Popović, Vera
AU  - Mihajlovski, Katarina
AU  - Milić, Marija
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5092
AB  - This study has explored the effect of three phytohormones application, based on α-naphthyl acetic acid, named INCIT 1, INCIT 8 and INCIT K, on the root system growing potential and rooting stimulation of Thymus pannonicus All. cuttings. This plant is highly reputable not only in a folk medicine, but also recognized in the business sector, due to a multiple uses and beneficial effects on human health.
The research was located in Veliko Središte, Vršac (Serbia) and conducted in May, 2021. The cuttings were dipped in a powdered formulation of phytohormones and placed in plastic containers pre-filled with commercial substrate. The phytohormone-free variant was taken as a control. After 2 months, the cuttings were removed and the morphological and biological properties (polyphenols content and antioxidant activity by DPPH radical and FRAP method) were measured.
Based on the morphological results, all of treated samples showed satisfactory behaviour, whereby the most suitable phytohormone to stimulate the growth of cuttings was INCIT 8, in which the average weight of the aboveground vegetative part of the plant and root mass were higher for more than 60% in relation to the control; the number of roots were about 25% higher, whereby the mass of the whole plant was almost 3 times increased. Considering the biological activities in a 5% aqueous infusions of the samples, it was found that the polyphenols content and the antioxidant activity were lowered in treated samples, with relation to the control, excluding the sample INCIT 8 where the FRAP value was slightly increased, while the inhibition of DPPH radicals was higher by around 15%.
The applied phytohormone treatment may ensure economically viable yields of standard or even improved plant quality. In the following period, it is expected that all of treated adult plants will have a higher content of biologically active substances.
PB  - University of Belgrade
C3  - UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts
T1  - The effect of phytohormones application on morphological and biological properties of Thymus pannonicus All.
SP  - 151
EP  - 151
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5092
ER  - 

@conference{
author = "Filipovć, Vladimir and Ugrenović, Vladan and Maksimović, Zoran and Dimitrijević, Snežana and Popović, Vera and Mihajlovski, Katarina and Milić, Marija",
year = "2021",
abstract = "This study has explored the effect of three phytohormones application, based on α-naphthyl acetic acid, named INCIT 1, INCIT 8 and INCIT K, on the root system growing potential and rooting stimulation of Thymus pannonicus All. cuttings. This plant is highly reputable not only in a folk medicine, but also recognized in the business sector, due to a multiple uses and beneficial effects on human health.
The research was located in Veliko Središte, Vršac (Serbia) and conducted in May, 2021. The cuttings were dipped in a powdered formulation of phytohormones and placed in plastic containers pre-filled with commercial substrate. The phytohormone-free variant was taken as a control. After 2 months, the cuttings were removed and the morphological and biological properties (polyphenols content and antioxidant activity by DPPH radical and FRAP method) were measured.
Based on the morphological results, all of treated samples showed satisfactory behaviour, whereby the most suitable phytohormone to stimulate the growth of cuttings was INCIT 8, in which the average weight of the aboveground vegetative part of the plant and root mass were higher for more than 60% in relation to the control; the number of roots were about 25% higher, whereby the mass of the whole plant was almost 3 times increased. Considering the biological activities in a 5% aqueous infusions of the samples, it was found that the polyphenols content and the antioxidant activity were lowered in treated samples, with relation to the control, excluding the sample INCIT 8 where the FRAP value was slightly increased, while the inhibition of DPPH radicals was higher by around 15%.
The applied phytohormone treatment may ensure economically viable yields of standard or even improved plant quality. In the following period, it is expected that all of treated adult plants will have a higher content of biologically active substances.",
publisher = "University of Belgrade",
journal = "UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts",
title = "The effect of phytohormones application on morphological and biological properties of Thymus pannonicus All.",
pages = "151-151",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5092"
}

Filipovć, V., Ugrenović, V., Maksimović, Z., Dimitrijević, S., Popović, V., Mihajlovski, K.,& Milić, M.. (2021). The effect of phytohormones application on morphological and biological properties of Thymus pannonicus All.. in UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts
University of Belgrade., 151-151.
https://hdl.handle.net/21.15107/rcub_farfar_5092

Filipovć V, Ugrenović V, Maksimović Z, Dimitrijević S, Popović V, Mihajlovski K, Milić M. The effect of phytohormones application on morphological and biological properties of Thymus pannonicus All.. in UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts. 2021;:151-151.
https://hdl.handle.net/21.15107/rcub_farfar_5092 .

Filipovć, Vladimir, Ugrenović, Vladan, Maksimović, Zoran, Dimitrijević, Snežana, Popović, Vera, Mihajlovski, Katarina, Milić, Marija, "The effect of phytohormones application on morphological and biological properties of Thymus pannonicus All." in UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts (2021):151-151,
https://hdl.handle.net/21.15107/rcub_farfar_5092 .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Đuriš, Jelena
AU  - Dapčević, Aleksandra
AU  - Lučić-Škorić, Marija
AU  - Medarević, Đorđe
AU  - Pavlović, Stefan
AU  - Ibrić, Svetlana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3782
AB  - This study investigates pharmaceutical polymers (Soluplus®, HPMCAS, and Eudragit® E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa and temperature of 100 °C during 2 h) enabled preparation of stable porous valsartan formulations which was confirmed with FESEM and mercury intrusion porosimetry analysis. The bulk density of obtained formulations was lower than 550 kg/m3. FTIR, DSC, and PXRD analysis indicated that there was no chemical interaction between the drug and polymers and that amorphous solid dispersions were obtained. Formulations with Soluplus® and HPMCAS retained its buoyancy in 0.1 M HCl for longer than 24 h, while formulation with Eudragit® E100 retained its buoyancy up to 2 h. Controlled valsartan release was influenced by solubility of polymers in the tested release medium, which was confirmed by UV/VIS spectroscopy. The obtained results provided framework for further development of floating drug delivery system using an environmental friendly process.
PB  - Springer Science and Business Media B.V.
T2  - Journal of Polymer Research
T1  - Preparation of floating polymer-valsartan delivery systems using supercritical CO2
VL  - 28
IS  - 3
DO  - 10.1007/s10965-021-02440-1
ER  - 

@article{
author = "Milovanović, Stoja and Đuriš, Jelena and Dapčević, Aleksandra and Lučić-Škorić, Marija and Medarević, Đorđe and Pavlović, Stefan and Ibrić, Svetlana",
year = "2021",
abstract = "This study investigates pharmaceutical polymers (Soluplus®, HPMCAS, and Eudragit® E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa and temperature of 100 °C during 2 h) enabled preparation of stable porous valsartan formulations which was confirmed with FESEM and mercury intrusion porosimetry analysis. The bulk density of obtained formulations was lower than 550 kg/m3. FTIR, DSC, and PXRD analysis indicated that there was no chemical interaction between the drug and polymers and that amorphous solid dispersions were obtained. Formulations with Soluplus® and HPMCAS retained its buoyancy in 0.1 M HCl for longer than 24 h, while formulation with Eudragit® E100 retained its buoyancy up to 2 h. Controlled valsartan release was influenced by solubility of polymers in the tested release medium, which was confirmed by UV/VIS spectroscopy. The obtained results provided framework for further development of floating drug delivery system using an environmental friendly process.",
publisher = "Springer Science and Business Media B.V.",
journal = "Journal of Polymer Research",
title = "Preparation of floating polymer-valsartan delivery systems using supercritical CO2",
volume = "28",
number = "3",
doi = "10.1007/s10965-021-02440-1"
}

Milovanović, S., Đuriš, J., Dapčević, A., Lučić-Škorić, M., Medarević, Đ., Pavlović, S.,& Ibrić, S.. (2021). Preparation of floating polymer-valsartan delivery systems using supercritical CO2. in Journal of Polymer Research
Springer Science and Business Media B.V.., 28(3).
https://doi.org/10.1007/s10965-021-02440-1

Milovanović S, Đuriš J, Dapčević A, Lučić-Škorić M, Medarević Đ, Pavlović S, Ibrić S. Preparation of floating polymer-valsartan delivery systems using supercritical CO2. in Journal of Polymer Research. 2021;28(3).
doi:10.1007/s10965-021-02440-1 .

Milovanović, Stoja, Đuriš, Jelena, Dapčević, Aleksandra, Lučić-Škorić, Marija, Medarević, Đorđe, Pavlović, Stefan, Ibrić, Svetlana, "Preparation of floating polymer-valsartan delivery systems using supercritical CO2" in Journal of Polymer Research, 28, no. 3 (2021),
https://doi.org/10.1007/s10965-021-02440-1 . .

TY  - JOUR
AU  - Jovanović, Marija
AU  - Petrović, Miloš
AU  - Cvijić, Sandra
AU  - Tomić, Nataša
AU  - Stojanović, Dušica
AU  - Ibrić, Svetlana
AU  - Uskoković, Petar
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4016
AB  - Gelatin-polyvinylpyrrolidone (PVP) and gelatin-poly(vinyl alcohol) (PVA) mucoadhesive buccal films loaded with propranolol hydrochloride (PRH) were prepared by semi-solid extrusion 3D printing. The aim of this study was to evaluate the effects of the synthetic polymers PVP and PVA on thermal and mechanical properties and drug release profiles of gelatin-based films. The Fourier-transform infrared spectroscopy showed that hydrogen bonding between gelatin and PVP formed during printing. In the other blend, neither the esterification of PVA nor gelatin occurred. Differential scanning calorimetry revealed the presence of partial helical structures. In line with these results, the mechanical properties and drug release profiles were different for each blend. Formulation with gelatin-PVP and PRH showed higher tensile strength, hardness, and adhesive strength but slower drug release than formulation with gelatin-PVA and PRH. The in silico population simulations indicated increased drug bioavailability and decreased inter-individual variations in the resulting pharmacokinetic profiles compared to immediate-release tablets. Moreover, the simulation results suggested that reduced PRH daily dosing can be achieved with prolonged-release buccal films, which improves patient compliance.
PB  - MDPI
T2  - Pharmaceutics
T1  - 3d printed buccal films for prolonged-release of propranolol hydrochloride: Development, characterization and bioavailability prediction
VL  - 13
IS  - 12
DO  - 10.3390/pharmaceutics13122143
ER  - 

@article{
author = "Jovanović, Marija and Petrović, Miloš and Cvijić, Sandra and Tomić, Nataša and Stojanović, Dušica and Ibrić, Svetlana and Uskoković, Petar",
year = "2021",
abstract = "Gelatin-polyvinylpyrrolidone (PVP) and gelatin-poly(vinyl alcohol) (PVA) mucoadhesive buccal films loaded with propranolol hydrochloride (PRH) were prepared by semi-solid extrusion 3D printing. The aim of this study was to evaluate the effects of the synthetic polymers PVP and PVA on thermal and mechanical properties and drug release profiles of gelatin-based films. The Fourier-transform infrared spectroscopy showed that hydrogen bonding between gelatin and PVP formed during printing. In the other blend, neither the esterification of PVA nor gelatin occurred. Differential scanning calorimetry revealed the presence of partial helical structures. In line with these results, the mechanical properties and drug release profiles were different for each blend. Formulation with gelatin-PVP and PRH showed higher tensile strength, hardness, and adhesive strength but slower drug release than formulation with gelatin-PVA and PRH. The in silico population simulations indicated increased drug bioavailability and decreased inter-individual variations in the resulting pharmacokinetic profiles compared to immediate-release tablets. Moreover, the simulation results suggested that reduced PRH daily dosing can be achieved with prolonged-release buccal films, which improves patient compliance.",
publisher = "MDPI",
journal = "Pharmaceutics",
title = "3d printed buccal films for prolonged-release of propranolol hydrochloride: Development, characterization and bioavailability prediction",
volume = "13",
number = "12",
doi = "10.3390/pharmaceutics13122143"
}

Jovanović, M., Petrović, M., Cvijić, S., Tomić, N., Stojanović, D., Ibrić, S.,& Uskoković, P.. (2021). 3d printed buccal films for prolonged-release of propranolol hydrochloride: Development, characterization and bioavailability prediction. in Pharmaceutics
MDPI., 13(12).
https://doi.org/10.3390/pharmaceutics13122143

Jovanović M, Petrović M, Cvijić S, Tomić N, Stojanović D, Ibrić S, Uskoković P. 3d printed buccal films for prolonged-release of propranolol hydrochloride: Development, characterization and bioavailability prediction. in Pharmaceutics. 2021;13(12).
doi:10.3390/pharmaceutics13122143 .

Jovanović, Marija, Petrović, Miloš, Cvijić, Sandra, Tomić, Nataša, Stojanović, Dušica, Ibrić, Svetlana, Uskoković, Petar, "3d printed buccal films for prolonged-release of propranolol hydrochloride: Development, characterization and bioavailability prediction" in Pharmaceutics, 13, no. 12 (2021),
https://doi.org/10.3390/pharmaceutics13122143 . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Pavun, Leposava
AU  - Dojčinović, Biljana
AU  - Kostić, Mirjana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3955
AB  - Raw jute fabric was chemically modified with 1 % NaOH for 30 min,  17.5 % NaOH for 5 min or with 0.7 % NaClO2 for 30 and 60 min to study the  influence of changes in the chemical composition of the fabrics and quantity of  carboxyl groups on the biosorption capacity of the fabrics for nickel ions. The  effects of contact time and initial concentration of nickel ions on the biosorp- tion capacity of the fabrics were also investigated. The obtained results rev- ealed that the biosorption of nickel ions can be explained by the pseudo-sec- ond-order kinetic model, while the experimental isotherm data fit better with  the Langmuir model. The calculated ratios between maximal biosorption cap- acity (6.30–12.06 mg g-1) of the jute fabrics and carboxyl group quantity indi- cated that approximately half of the carboxyl groups of the fabrics’ would be  involved in binding nickel ions during biosorption. Therefore, the quantity of  carboxyl groups can be used to predict the maximal biosorption capacity of jute  fabrics toward nickel ions. In the case of oxidized jute fabrics, the lignin rem- oval, and consequently increased content of cellulose and hemicelluloses, also  contributed to a higher biosorption capacity.
AB  - Сирова тканина од јуте је хемијски модификована 1 % NaOH у току 30 min, 17,5 %  NaOH у току 5 min или 0,7 % NaClO2 у току 30 и 60 min у циљу испитивања утицаја промена хемијског састава и садржаја карбоксилних група на биосорпциони капацитет тканина  према  јонима  никла.  Такође,  испитиван  је  и  утицај  времена  контакта  тканина  са  раствором  NiSO4  и  почетне  концентрације  раствора  никла  на  биосорпциони  капацитет  тканина од јуте. Добијени резултати указују на то да се процес биосорпције никла може  описати  кинетичким  моделом  псеудо-другог  реда,  а  равнотежне  вредности  добијене  за  сорпцију никла се боље слажу са Langmuir адсорпционом изотермом. Израчунати однос  између  максималних  биосорпционих  капацитета  тканина  од  јуте  (6,30–12,06  mg  g-1)  и  садржаја  карбоксилних  група  указују  на  то  да  ће  приближно  половина  карбоксилних  група  учествовати  у  везивању  јона  никла  током  биосорпције.  Према  томе,  садржај  карбоксилних  група  се  може  користити  као  индикатор  максималног  биосорпционог  капацитета тканина од јуте према јонима никла. Код оксидисане тканине, уклањање лигнина  које  је  праћено  са  повећањем  садржаја  целулозе  и  хемицелулоза  је  такође  допринело  већем биосорпционом капацитету.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics
T1  - Биосорпција јона никла на тканинама од јуте: кинетичка и  изотермска испитивања
VL  - 86
IS  - 9
SP  - 885
EP  - 897
DO  - 10.2298/JSC210209030I
ER  - 

@article{
author = "Ivanovska, Aleksandra and Pavun, Leposava and Dojčinović, Biljana and Kostić, Mirjana",
year = "2021",
abstract = "Raw jute fabric was chemically modified with 1 % NaOH for 30 min,  17.5 % NaOH for 5 min or with 0.7 % NaClO2 for 30 and 60 min to study the  influence of changes in the chemical composition of the fabrics and quantity of  carboxyl groups on the biosorption capacity of the fabrics for nickel ions. The  effects of contact time and initial concentration of nickel ions on the biosorp- tion capacity of the fabrics were also investigated. The obtained results rev- ealed that the biosorption of nickel ions can be explained by the pseudo-sec- ond-order kinetic model, while the experimental isotherm data fit better with  the Langmuir model. The calculated ratios between maximal biosorption cap- acity (6.30–12.06 mg g-1) of the jute fabrics and carboxyl group quantity indi- cated that approximately half of the carboxyl groups of the fabrics’ would be  involved in binding nickel ions during biosorption. Therefore, the quantity of  carboxyl groups can be used to predict the maximal biosorption capacity of jute  fabrics toward nickel ions. In the case of oxidized jute fabrics, the lignin rem- oval, and consequently increased content of cellulose and hemicelluloses, also  contributed to a higher biosorption capacity., Сирова тканина од јуте је хемијски модификована 1 % NaOH у току 30 min, 17,5 %  NaOH у току 5 min или 0,7 % NaClO2 у току 30 и 60 min у циљу испитивања утицаја промена хемијског састава и садржаја карбоксилних група на биосорпциони капацитет тканина  према  јонима  никла.  Такође,  испитиван  је  и  утицај  времена  контакта  тканина  са  раствором  NiSO4  и  почетне  концентрације  раствора  никла  на  биосорпциони  капацитет  тканина од јуте. Добијени резултати указују на то да се процес биосорпције никла може  описати  кинетичким  моделом  псеудо-другог  реда,  а  равнотежне  вредности  добијене  за  сорпцију никла се боље слажу са Langmuir адсорпционом изотермом. Израчунати однос  између  максималних  биосорпционих  капацитета  тканина  од  јуте  (6,30–12,06  mg  g-1)  и  садржаја  карбоксилних  група  указују  на  то  да  ће  приближно  половина  карбоксилних  група  учествовати  у  везивању  јона  никла  током  биосорпције.  Према  томе,  садржај  карбоксилних  група  се  може  користити  као  индикатор  максималног  биосорпционог  капацитета тканина од јуте према јонима никла. Код оксидисане тканине, уклањање лигнина  које  је  праћено  са  повећањем  садржаја  целулозе  и  хемицелулоза  је  такође  допринело  већем биосорпционом капацитету.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics, Биосорпција јона никла на тканинама од јуте: кинетичка и  изотермска испитивања",
volume = "86",
number = "9",
pages = "885-897",
doi = "10.2298/JSC210209030I"
}

Ivanovska, A., Pavun, L., Dojčinović, B.,& Kostić, M.. (2021). Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 86(9), 885-897.
https://doi.org/10.2298/JSC210209030I

Ivanovska A, Pavun L, Dojčinović B, Kostić M. Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics. in Journal of the Serbian Chemical Society. 2021;86(9):885-897.
doi:10.2298/JSC210209030I .

Ivanovska, Aleksandra, Pavun, Leposava, Dojčinović, Biljana, Kostić, Mirjana, "Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics" in Journal of the Serbian Chemical Society, 86, no. 9 (2021):885-897,
https://doi.org/10.2298/JSC210209030I . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Antonijević, Biljana
AU  - Cvijetić, Ilija
AU  - Mijin, Dušan
AU  - Kostić, Mirjana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3939
AB  - The objective of this investigation was to obtain jute fabrics with enhanced sorption properties (by using simple and cost-effective alkali and oxidative modifications) and a long life cycle. The applied alkali modifications lead to hemicellulose removal and decreased the fibers’ crystallinity, both contributing to enhanced fibers’ sorption properties, i.e., water retention power and degree of fibers’ swelling up to 49 % and 70 %, respectively. A connection between cellulose polymorphs’ (cellulose I and cellulose II) contents (determined by XRD), fibers’ surface morphology (verified by FESEM), fabrics’ crimp, and capillarity of jute fabrics modified with 17.5 % NaOH was established. During the oxidative modifications, significant changes in jute fibers’ chemical composition and structure (i.e., lignin removal and more homogeneous middle lamellae) occurred which further resulted in enhanced jute fabrics’ water retention power and capillarity as well as fibers’ swelling up to 80 %, 75 %, and 54 %, compared to the raw jute, respectively. In order to move towards a circular economy and to ensure the recycling and re-use of recycled fabrics, the jute fabrics with enhanced sorption properties were evaluated as biosorbents for anthraquinone dye C. I. Acid Blue 111. The obtained results revealed that the jute fabrics’ maximum biosorption capacities for this dye ranged from 12.94 to 18.97 mg/g, while the equilibrium adsorption data were highly consistent with the Langmuir isotherm model. Moreover, based on the predicted dye pKa values, the fabric zeta potential, content of carboxyl and aldehyde groups as well as hydrogen bond intensity (determined by ATR-FTIR), a possible mechanism of the dye biosorption onto jute fabric waste was proposed.
PB  - Elsevier B.V.
T2  - Industrial Crops and Products
T1  - Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle
VL  - 171
DO  - 10.1016/j.indcrop.2021.113913
ER  - 

@article{
author = "Ivanovska, Aleksandra and Lađarević, Jelena and Pavun, Leposava and Antonijević, Biljana and Cvijetić, Ilija and Mijin, Dušan and Kostić, Mirjana",
year = "2021",
abstract = "The objective of this investigation was to obtain jute fabrics with enhanced sorption properties (by using simple and cost-effective alkali and oxidative modifications) and a long life cycle. The applied alkali modifications lead to hemicellulose removal and decreased the fibers’ crystallinity, both contributing to enhanced fibers’ sorption properties, i.e., water retention power and degree of fibers’ swelling up to 49 % and 70 %, respectively. A connection between cellulose polymorphs’ (cellulose I and cellulose II) contents (determined by XRD), fibers’ surface morphology (verified by FESEM), fabrics’ crimp, and capillarity of jute fabrics modified with 17.5 % NaOH was established. During the oxidative modifications, significant changes in jute fibers’ chemical composition and structure (i.e., lignin removal and more homogeneous middle lamellae) occurred which further resulted in enhanced jute fabrics’ water retention power and capillarity as well as fibers’ swelling up to 80 %, 75 %, and 54 %, compared to the raw jute, respectively. In order to move towards a circular economy and to ensure the recycling and re-use of recycled fabrics, the jute fabrics with enhanced sorption properties were evaluated as biosorbents for anthraquinone dye C. I. Acid Blue 111. The obtained results revealed that the jute fabrics’ maximum biosorption capacities for this dye ranged from 12.94 to 18.97 mg/g, while the equilibrium adsorption data were highly consistent with the Langmuir isotherm model. Moreover, based on the predicted dye pKa values, the fabric zeta potential, content of carboxyl and aldehyde groups as well as hydrogen bond intensity (determined by ATR-FTIR), a possible mechanism of the dye biosorption onto jute fabric waste was proposed.",
publisher = "Elsevier B.V.",
journal = "Industrial Crops and Products",
title = "Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle",
volume = "171",
doi = "10.1016/j.indcrop.2021.113913"
}

Ivanovska, A., Lađarević, J., Pavun, L., Antonijević, B., Cvijetić, I., Mijin, D.,& Kostić, M.. (2021). Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle. in Industrial Crops and Products
Elsevier B.V.., 171.
https://doi.org/10.1016/j.indcrop.2021.113913

Ivanovska A, Lađarević J, Pavun L, Antonijević B, Cvijetić I, Mijin D, Kostić M. Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle. in Industrial Crops and Products. 2021;171.
doi:10.1016/j.indcrop.2021.113913 .

Ivanovska, Aleksandra, Lađarević, Jelena, Pavun, Leposava, Antonijević, Biljana, Cvijetić, Ilija, Mijin, Dušan, Kostić, Mirjana, "Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle" in Industrial Crops and Products, 171 (2021),
https://doi.org/10.1016/j.indcrop.2021.113913 . .

TY  - JOUR
AU  - Jovanović, Marija
AU  - Tomić, Nataša
AU  - Cvijić, Sandra
AU  - Stojanović, Dušica
AU  - Ibrić, Svetlana
AU  - Uskoković, Petar
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3804
AB  - This study processes and characterizes propranolol hydrochloride/gelatin mucoadhesivebuccal films.  Two types of gelatin are used:  Gelatin from porcine skin, type A (GA), and gelatinfrom bovine skin (GB). The influence of gelatin type on mechanical, mucoadhesive, and biopharma-ceutical characteristics of buccal films is evaluated. Fourier-Transfer infrared spectroscopy (FTIR)and differential scanning calorimetry (DSC) analysis show that GA with propranolol hydrochloride(PRH) in the film (GAP) formed a physical mixture, whereas GB with PRH (GBP) form a compound-complex. Results of mechanical testing (tensile test, hardness) revealed that GAP films exhibit higherelastic modulus, tensile strength, and hardness.  A mucoahesion test shows that GBP has higheradhesion strength, while GAP shows higher work of adhesion. Bothin vitrorelease study and insilico simulation indicated that processed films can provide effective drug transport through thebuccal mucosa. In silico simulation shows improved bioavailability from buccal films, in comparisonto the immediate-release tablets—indicating that the therapeutic drug dose can be markedly reduced.
PB  - MDPI AG
T2  - Pharmaceutics
T1  - Mucoadhesive gelatin buccal films with propranolol hydrochloride: Evaluation of mechanical, mucoadhesive, and biopharmaceutical properties
VL  - 13
IS  - 2
SP  - 1
EP  - 19
DO  - 10.3390/pharmaceutics13020273
ER  - 

@article{
author = "Jovanović, Marija and Tomić, Nataša and Cvijić, Sandra and Stojanović, Dušica and Ibrić, Svetlana and Uskoković, Petar",
year = "2021",
abstract = "This study processes and characterizes propranolol hydrochloride/gelatin mucoadhesivebuccal films.  Two types of gelatin are used:  Gelatin from porcine skin, type A (GA), and gelatinfrom bovine skin (GB). The influence of gelatin type on mechanical, mucoadhesive, and biopharma-ceutical characteristics of buccal films is evaluated. Fourier-Transfer infrared spectroscopy (FTIR)and differential scanning calorimetry (DSC) analysis show that GA with propranolol hydrochloride(PRH) in the film (GAP) formed a physical mixture, whereas GB with PRH (GBP) form a compound-complex. Results of mechanical testing (tensile test, hardness) revealed that GAP films exhibit higherelastic modulus, tensile strength, and hardness.  A mucoahesion test shows that GBP has higheradhesion strength, while GAP shows higher work of adhesion. Bothin vitrorelease study and insilico simulation indicated that processed films can provide effective drug transport through thebuccal mucosa. In silico simulation shows improved bioavailability from buccal films, in comparisonto the immediate-release tablets—indicating that the therapeutic drug dose can be markedly reduced.",
publisher = "MDPI AG",
journal = "Pharmaceutics",
title = "Mucoadhesive gelatin buccal films with propranolol hydrochloride: Evaluation of mechanical, mucoadhesive, and biopharmaceutical properties",
volume = "13",
number = "2",
pages = "1-19",
doi = "10.3390/pharmaceutics13020273"
}

Jovanović, M., Tomić, N., Cvijić, S., Stojanović, D., Ibrić, S.,& Uskoković, P.. (2021). Mucoadhesive gelatin buccal films with propranolol hydrochloride: Evaluation of mechanical, mucoadhesive, and biopharmaceutical properties. in Pharmaceutics
MDPI AG., 13(2), 1-19.
https://doi.org/10.3390/pharmaceutics13020273

Jovanović M, Tomić N, Cvijić S, Stojanović D, Ibrić S, Uskoković P. Mucoadhesive gelatin buccal films with propranolol hydrochloride: Evaluation of mechanical, mucoadhesive, and biopharmaceutical properties. in Pharmaceutics. 2021;13(2):1-19.
doi:10.3390/pharmaceutics13020273 .

Jovanović, Marija, Tomić, Nataša, Cvijić, Sandra, Stojanović, Dušica, Ibrić, Svetlana, Uskoković, Petar, "Mucoadhesive gelatin buccal films with propranolol hydrochloride: Evaluation of mechanical, mucoadhesive, and biopharmaceutical properties" in Pharmaceutics, 13, no. 2 (2021):1-19,
https://doi.org/10.3390/pharmaceutics13020273 . .

TY  - JOUR
AU  - Ivanovska, A.
AU  - Asanović, Koviljka
AU  - Jankoska, Maja
AU  - Mihajlovski, Katarina
AU  - Pavun, Leposava
AU  - Kostić, Mirjana
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3646
AB  - Abstract: The aim of the present research is first to reduce the jute fabric non-cellulosic components by using different chemical modifications (i.e. alkali and oxidative) and then to analyze their influence on the jute fabric properties. For that purpose, the jute fabrics were characterized in terms of their chemical composition, structural parameters, mechanical properties, volume electrical resistivity, antibacterial activity and biosorption of Zn2+. Moreover, the jute fabrics were functionalized by incorporation of silver ions and the fabrics were evaluated as sorption material with a further perspective of reuse. After the alkali modifications, the hemicelluloses were selectively removed and the fabric structural parameters increased. Alkali modifications under mild conditions (1% NaOH for 30 min and 5% NaOH for 5 min) lead to a decrease, while the most intensive alkali modification (17.5% NaOH for 30 min) contributed to an increase in the volume electrical resistivity and fabric maximum force compared to unmodified fabric. A relationship between the jute fabric chemical composition, crystallinity index, conversion of cellulose I to cellulose II, fabric structural parameters and volume electrical resistivity was found. The oxidations lead to selective lignin removal, which consequently causes a decrease in the volume electrical resistivity and fabric maximum force. Ag+ incorporated in the selected samples decreased their electrical resistivity even further. Following the increased focus on the concept of circular economy and sustainable development goals, the biosorption potential of damaged and waste jute fabrics for Zn2+ was investigated. Jute fabrics with incorporated Ag+ and those obtained after the biosorption of Zn2+ provided maximum bacterial reduction (99.99%) for Escherichia coli and Staphylococcus aureus. The chemically modified jute fabrics can be utilized as carpet backing and protective clothing in environments sensitive to electrical discharges, but also as filters for water disinfection and biosorbents for Zn2+.Graphic abstract: [Figure not available: see fulltext.].
PB  - Springer Nature B.V.
T2  - Cellulose
T1  - Multifunctional jute fabrics obtained by different chemical modifications
VL  - 27
SP  - 8485
EP  - 8502
DO  - 10.1007/s10570-020-03360-x
ER  - 

@article{
author = "Ivanovska, A. and Asanović, Koviljka and Jankoska, Maja and Mihajlovski, Katarina and Pavun, Leposava and Kostić, Mirjana",
year = "2020",
abstract = "Abstract: The aim of the present research is first to reduce the jute fabric non-cellulosic components by using different chemical modifications (i.e. alkali and oxidative) and then to analyze their influence on the jute fabric properties. For that purpose, the jute fabrics were characterized in terms of their chemical composition, structural parameters, mechanical properties, volume electrical resistivity, antibacterial activity and biosorption of Zn2+. Moreover, the jute fabrics were functionalized by incorporation of silver ions and the fabrics were evaluated as sorption material with a further perspective of reuse. After the alkali modifications, the hemicelluloses were selectively removed and the fabric structural parameters increased. Alkali modifications under mild conditions (1% NaOH for 30 min and 5% NaOH for 5 min) lead to a decrease, while the most intensive alkali modification (17.5% NaOH for 30 min) contributed to an increase in the volume electrical resistivity and fabric maximum force compared to unmodified fabric. A relationship between the jute fabric chemical composition, crystallinity index, conversion of cellulose I to cellulose II, fabric structural parameters and volume electrical resistivity was found. The oxidations lead to selective lignin removal, which consequently causes a decrease in the volume electrical resistivity and fabric maximum force. Ag+ incorporated in the selected samples decreased their electrical resistivity even further. Following the increased focus on the concept of circular economy and sustainable development goals, the biosorption potential of damaged and waste jute fabrics for Zn2+ was investigated. Jute fabrics with incorporated Ag+ and those obtained after the biosorption of Zn2+ provided maximum bacterial reduction (99.99%) for Escherichia coli and Staphylococcus aureus. The chemically modified jute fabrics can be utilized as carpet backing and protective clothing in environments sensitive to electrical discharges, but also as filters for water disinfection and biosorbents for Zn2+.Graphic abstract: [Figure not available: see fulltext.].",
publisher = "Springer Nature B.V.",
journal = "Cellulose",
title = "Multifunctional jute fabrics obtained by different chemical modifications",
volume = "27",
pages = "8485-8502",
doi = "10.1007/s10570-020-03360-x"
}

Ivanovska, A., Asanović, K., Jankoska, M., Mihajlovski, K., Pavun, L.,& Kostić, M.. (2020). Multifunctional jute fabrics obtained by different chemical modifications. in Cellulose
Springer Nature B.V.., 27, 8485-8502.
https://doi.org/10.1007/s10570-020-03360-x

Ivanovska A, Asanović K, Jankoska M, Mihajlovski K, Pavun L, Kostić M. Multifunctional jute fabrics obtained by different chemical modifications. in Cellulose. 2020;27:8485-8502.
doi:10.1007/s10570-020-03360-x .

Ivanovska, A., Asanović, Koviljka, Jankoska, Maja, Mihajlovski, Katarina, Pavun, Leposava, Kostić, Mirjana, "Multifunctional jute fabrics obtained by different chemical modifications" in Cellulose, 27 (2020):8485-8502,
https://doi.org/10.1007/s10570-020-03360-x . .