TY  - JOUR
AU  - Obradović, Milan
AU  - Zafirović, Sonja
AU  - Essack, Magbubah
AU  - Dimitrov, Jelena
AU  - Živković, Lada
AU  - Spremo-Potparević, Biljana
AU  - Radak, Đorđe
AU  - Bajić, Vladimir B.
AU  - Isenović, Esma
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3462
AB  - To remedy carotid artery stenosis and prevent stroke surgical intervention is commonly used, and the gold standard being carotid endarterectomy (CEA). During CEA cerebrovascular hemoglobin oxygen saturation decreases and when this decrease reaches critical levels it leads to cerebral hypoxia that causes neuronal damage. One of the proposed mechanism that affects changes during CEA and contribute to acute brain ischemia (ABI) is oxidative stress. The increased production of reactive oxygen species and reactive nitrogen species during ABI may cause an unregulated inflammatory response and further lead to structural and functional injury of neurons. Antioxidant activity are involved in the protection against neuronal damage after cerebral ischemia. We hypothesized that neuronal injury and poor outcomes in patients undergoing CEA may be results of oxidative stress that disturbed function of antioxidant enzymes and contributed to the DNA damage in lymphocytes.
PB  - Elsevier
T2  - Medical Hypotheses
T1  - Antioxidant enzymes expression in lymphocytes of patients undergoing carotid endarterectomy
VL  - 134
SP  - 1
EP  - 5
DO  - 10.1016/j.mehy.2019.109419
ER  - 

@article{
author = "Obradović, Milan and Zafirović, Sonja and Essack, Magbubah and Dimitrov, Jelena and Živković, Lada and Spremo-Potparević, Biljana and Radak, Đorđe and Bajić, Vladimir B. and Isenović, Esma",
year = "2020",
abstract = "To remedy carotid artery stenosis and prevent stroke surgical intervention is commonly used, and the gold standard being carotid endarterectomy (CEA). During CEA cerebrovascular hemoglobin oxygen saturation decreases and when this decrease reaches critical levels it leads to cerebral hypoxia that causes neuronal damage. One of the proposed mechanism that affects changes during CEA and contribute to acute brain ischemia (ABI) is oxidative stress. The increased production of reactive oxygen species and reactive nitrogen species during ABI may cause an unregulated inflammatory response and further lead to structural and functional injury of neurons. Antioxidant activity are involved in the protection against neuronal damage after cerebral ischemia. We hypothesized that neuronal injury and poor outcomes in patients undergoing CEA may be results of oxidative stress that disturbed function of antioxidant enzymes and contributed to the DNA damage in lymphocytes.",
publisher = "Elsevier",
journal = "Medical Hypotheses",
title = "Antioxidant enzymes expression in lymphocytes of patients undergoing carotid endarterectomy",
volume = "134",
pages = "1-5",
doi = "10.1016/j.mehy.2019.109419"
}

Obradović, M., Zafirović, S., Essack, M., Dimitrov, J., Živković, L., Spremo-Potparević, B., Radak, Đ., Bajić, V. B.,& Isenović, E.. (2020). Antioxidant enzymes expression in lymphocytes of patients undergoing carotid endarterectomy. in Medical Hypotheses
Elsevier., 134, 1-5.
https://doi.org/10.1016/j.mehy.2019.109419

Obradović M, Zafirović S, Essack M, Dimitrov J, Živković L, Spremo-Potparević B, Radak Đ, Bajić VB, Isenović E. Antioxidant enzymes expression in lymphocytes of patients undergoing carotid endarterectomy. in Medical Hypotheses. 2020;134:1-5.
doi:10.1016/j.mehy.2019.109419 .

Obradović, Milan, Zafirović, Sonja, Essack, Magbubah, Dimitrov, Jelena, Živković, Lada, Spremo-Potparević, Biljana, Radak, Đorđe, Bajić, Vladimir B., Isenović, Esma, "Antioxidant enzymes expression in lymphocytes of patients undergoing carotid endarterectomy" in Medical Hypotheses, 134 (2020):1-5,
https://doi.org/10.1016/j.mehy.2019.109419 . .

TY  - JOUR
AU  - Nenezić, Dragoslav
AU  - Tanasković, Slobodan
AU  - Gajin, Predrag
AU  - Ilijevski, Nenad
AU  - Novaković, Aleksandra
AU  - Radak, Đorđe
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2423
AB  - Introduction: In this report, we aim to present a rare case of isolated internal iliac artery aneurysm with associated left ureteric obstruction and consequent hydronephrosis. Case report: A 66-year-old male patient was admitted for occasional pain in the lower back that appeared one month earlier. CT arteriography revealed isolated internal iliac artery (diameter 99 mm) with ureteral obstruction, hydroureter and left kidney hydronephrosis occurrence. Aneurysm was resected, after six months the patient was doing well. Bearing in mind that 77% of the patients with isolated internal iliac artery have symptoms caused by aneurysmal compression on adjacent organs, we wanted to highlight that despite the amazing expansion of endovascular procedures in the last decades, its therapeutic effect in isolated internal iliac artery's treatment is to a great extent limited since compression symptoms cannot be solved. Conclusion: Open surgery remains the gold standard for isolated internal iliac artery's treatment considering significant limitations of endovascular procedures due to the inability to eliminate problems caused by compression.
PB  - Sage Publications Ltd, London
T2  - Vascular Pharmacology
T1  - A rare case of large isolated internal iliac artery aneurysm with ureteral obstruction and hydronephrosis: Compression symptoms are limitation for endovascular procedures
VL  - 23
IS  - 2
SP  - 170
EP  - 175
DO  - 10.1177/1708538114533963
ER  - 

@article{
author = "Nenezić, Dragoslav and Tanasković, Slobodan and Gajin, Predrag and Ilijevski, Nenad and Novaković, Aleksandra and Radak, Đorđe",
year = "2015",
abstract = "Introduction: In this report, we aim to present a rare case of isolated internal iliac artery aneurysm with associated left ureteric obstruction and consequent hydronephrosis. Case report: A 66-year-old male patient was admitted for occasional pain in the lower back that appeared one month earlier. CT arteriography revealed isolated internal iliac artery (diameter 99 mm) with ureteral obstruction, hydroureter and left kidney hydronephrosis occurrence. Aneurysm was resected, after six months the patient was doing well. Bearing in mind that 77% of the patients with isolated internal iliac artery have symptoms caused by aneurysmal compression on adjacent organs, we wanted to highlight that despite the amazing expansion of endovascular procedures in the last decades, its therapeutic effect in isolated internal iliac artery's treatment is to a great extent limited since compression symptoms cannot be solved. Conclusion: Open surgery remains the gold standard for isolated internal iliac artery's treatment considering significant limitations of endovascular procedures due to the inability to eliminate problems caused by compression.",
publisher = "Sage Publications Ltd, London",
journal = "Vascular Pharmacology",
title = "A rare case of large isolated internal iliac artery aneurysm with ureteral obstruction and hydronephrosis: Compression symptoms are limitation for endovascular procedures",
volume = "23",
number = "2",
pages = "170-175",
doi = "10.1177/1708538114533963"
}

Nenezić, D., Tanasković, S., Gajin, P., Ilijevski, N., Novaković, A.,& Radak, Đ.. (2015). A rare case of large isolated internal iliac artery aneurysm with ureteral obstruction and hydronephrosis: Compression symptoms are limitation for endovascular procedures. in Vascular Pharmacology
Sage Publications Ltd, London., 23(2), 170-175.
https://doi.org/10.1177/1708538114533963

Nenezić D, Tanasković S, Gajin P, Ilijevski N, Novaković A, Radak Đ. A rare case of large isolated internal iliac artery aneurysm with ureteral obstruction and hydronephrosis: Compression symptoms are limitation for endovascular procedures. in Vascular Pharmacology. 2015;23(2):170-175.
doi:10.1177/1708538114533963 .

Nenezić, Dragoslav, Tanasković, Slobodan, Gajin, Predrag, Ilijevski, Nenad, Novaković, Aleksandra, Radak, Đorđe, "A rare case of large isolated internal iliac artery aneurysm with ureteral obstruction and hydronephrosis: Compression symptoms are limitation for endovascular procedures" in Vascular Pharmacology, 23, no. 2 (2015):170-175,
https://doi.org/10.1177/1708538114533963 . .