TY  - JOUR
AU  - Jovanović, Zoran
AU  - Mravik, Željko
AU  - Bajuk-Bogdanović, Danica
AU  - Jovanović, Sonja
AU  - Marković, S.
AU  - Vujković, Milica
AU  - Kovač, Janez
AU  - Vengust, Damjan
AU  - Uskoković-Marković, Snežana
AU  - Holclajtner-Antunović, Ivanka
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3452
AB  - In the present study we investigated the interaction between 12-tungstophosphoric acid (WPA) and graphene oxide (GO) in their nanocomposite by utilizing the loading of WPA as an intrinsic parameter for interaction tuning. The Fourier-transform infrared spectroscopy, temperature-programmed desorption, X-ray photoelectron spectroscopy, zeta-potential measurements, thermogravimetric analysis, X-ray diffraction, Raman spectroscopy and transmission electron microscopy methods revealed that ∼5–13 wt% of WPA represents critical loading that separates two distinct contributions to GO-WPA interaction. This was explained by the self-limiting nature of GO-WPA interaction, initially controlled by high dispersion of WPA on GO (up to 13 wt%), that is eventually overpowered by WPA-WPA interaction as loading increases. As a result, the WPA agglomerates are being formed because of which the hybrid character of the nanocomposite diminishes, i.e., the properties of independent components start to be manifested to greater extent. The obtained results provide an important framework for considering possible outcomes in other 2D-0D systems, whose interaction is relevant both from fundamental and applicative point of view. Thus, the GO/WPA nanocomposite illustrates how the interactions between the components can be used for tuning the properties of nanocomposite as a whole.
PB  - Elsevier
T2  - Carbon
T1  - Self-limiting interactions in 2D–0D system: A case study of graphene oxide and 12-tungstophosphoric acid nanocomposite
VL  - 156
SP  - 166
EP  - 178
DO  - 10.1016/j.carbon.2019.09.072
ER  - 

@article{
author = "Jovanović, Zoran and Mravik, Željko and Bajuk-Bogdanović, Danica and Jovanović, Sonja and Marković, S. and Vujković, Milica and Kovač, Janez and Vengust, Damjan and Uskoković-Marković, Snežana and Holclajtner-Antunović, Ivanka",
year = "2020",
abstract = "In the present study we investigated the interaction between 12-tungstophosphoric acid (WPA) and graphene oxide (GO) in their nanocomposite by utilizing the loading of WPA as an intrinsic parameter for interaction tuning. The Fourier-transform infrared spectroscopy, temperature-programmed desorption, X-ray photoelectron spectroscopy, zeta-potential measurements, thermogravimetric analysis, X-ray diffraction, Raman spectroscopy and transmission electron microscopy methods revealed that ∼5–13 wt% of WPA represents critical loading that separates two distinct contributions to GO-WPA interaction. This was explained by the self-limiting nature of GO-WPA interaction, initially controlled by high dispersion of WPA on GO (up to 13 wt%), that is eventually overpowered by WPA-WPA interaction as loading increases. As a result, the WPA agglomerates are being formed because of which the hybrid character of the nanocomposite diminishes, i.e., the properties of independent components start to be manifested to greater extent. The obtained results provide an important framework for considering possible outcomes in other 2D-0D systems, whose interaction is relevant both from fundamental and applicative point of view. Thus, the GO/WPA nanocomposite illustrates how the interactions between the components can be used for tuning the properties of nanocomposite as a whole.",
publisher = "Elsevier",
journal = "Carbon",
title = "Self-limiting interactions in 2D–0D system: A case study of graphene oxide and 12-tungstophosphoric acid nanocomposite",
volume = "156",
pages = "166-178",
doi = "10.1016/j.carbon.2019.09.072"
}

Jovanović, Z., Mravik, Ž., Bajuk-Bogdanović, D., Jovanović, S., Marković, S., Vujković, M., Kovač, J., Vengust, D., Uskoković-Marković, S.,& Holclajtner-Antunović, I.. (2020). Self-limiting interactions in 2D–0D system: A case study of graphene oxide and 12-tungstophosphoric acid nanocomposite. in Carbon
Elsevier., 156, 166-178.
https://doi.org/10.1016/j.carbon.2019.09.072

Jovanović Z, Mravik Ž, Bajuk-Bogdanović D, Jovanović S, Marković S, Vujković M, Kovač J, Vengust D, Uskoković-Marković S, Holclajtner-Antunović I. Self-limiting interactions in 2D–0D system: A case study of graphene oxide and 12-tungstophosphoric acid nanocomposite. in Carbon. 2020;156:166-178.
doi:10.1016/j.carbon.2019.09.072 .

Jovanović, Zoran, Mravik, Željko, Bajuk-Bogdanović, Danica, Jovanović, Sonja, Marković, S., Vujković, Milica, Kovač, Janez, Vengust, Damjan, Uskoković-Marković, Snežana, Holclajtner-Antunović, Ivanka, "Self-limiting interactions in 2D–0D system: A case study of graphene oxide and 12-tungstophosphoric acid nanocomposite" in Carbon, 156 (2020):166-178,
https://doi.org/10.1016/j.carbon.2019.09.072 . .

TY  - CONF
AU  - Dimitrijević, Aleksandra
AU  - Jocić, Ana
AU  - Marić, Slađana
AU  - Zdolšek, Nikola
AU  - Trtić-Petrović, Tatjana
AU  - Vraneš, Milan
AU  - Gadžurić, Slobodan
AU  - Arsenijević, Jelena
AU  - Ražić, Slavica
AU  - Tavares, Ana Paula M.
AU  - Freire, Mara G.
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5288
AB  - The chemotherapeutic parthenolide (PTL) has an excellent
potential in the treatment of acute lymphoblastic leukemia and
much attention has been focused to overcome its poor aqueous
solubility, which limits PTL bioavailability. The most promising
approach is using micellar structures of Pluronics (class of triblock
copolymer of poly(ethylene)-poly(propylene)-poly(ethylene)),
as a drug delivery vectors. Pluronic PE6200 (PL6200) is selected
as one of the phase formers of aqueous biphasic system (ABS)
having in mind the amphiphilic nature of Pluronics which enables
good solubilization of hydrophobic molecules, their biocompatibility,
water solubility and complex mesophase behaviour. ABSs
are formed by combination of aqueous solutions of two polymers,
two salts or polymer/salt above certain concentrations with water
as the main constituent of both phases of ABS. In the quest for
more selective, performant and “greener” extraction technique of
PTL from natural matrices, a novel ABS comprised of a hydrophilic
ionic liquid (IL) - cholinium pyruvate (ChPyr) and PL6200
was investigated. In order to design selective Pluronic-mediated
purification process, (1) the ternary phase diagram was determinated
and characterised and (2) the partition of hydrophobic
PTL in this system was evaluated. A solution composed of 20
wt% of ChPyr + 30 wt% of PL6200 + 50 wt% of water with PTL
concentration of 2 mgml-1 led to high PTL extraction efficiency in
PL6200-rich phase (above 82%) with partition coefficient of 4.96.
The partition of PTL is mainly driven by its hydrophobic interaction
with poloxamer. For lower PL6200 concentrations in ABS,
formation of micelle particles was observed, what enabled solubilization
of PTL and its migration to hydrophilic IL-rich phase.
That decreased the PTL extraction efficiency toward PL6200-
rich phase. The obtained results showed that using cholinium-IL
/ Pluronic based ABS is promising alternative to volatile organic solvents that are nowdays used for extraction of PTL. Moreover,
using the Pluronic as constituent of ABS can provide the possibility
to simultaneously deal with low aqueous solubility of PTL by
forming the drug-loaded micelle particles and selective extraction
of active compound from real matrix.
PB  - Turkish Chemical Society
C3  - XX Euroanalysis 2019 Conference, Abstracts and Proceedings
T1  - Controlling of the parthenolide partition using micelle structures of block copolymer in ionic liquid based aqueous biphasic system
SP  - 212
EP  - 214
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5288
ER  - 

@conference{
author = "Dimitrijević, Aleksandra and Jocić, Ana and Marić, Slađana and Zdolšek, Nikola and Trtić-Petrović, Tatjana and Vraneš, Milan and Gadžurić, Slobodan and Arsenijević, Jelena and Ražić, Slavica and Tavares, Ana Paula M. and Freire, Mara G.",
year = "2019",
abstract = "The chemotherapeutic parthenolide (PTL) has an excellent
potential in the treatment of acute lymphoblastic leukemia and
much attention has been focused to overcome its poor aqueous
solubility, which limits PTL bioavailability. The most promising
approach is using micellar structures of Pluronics (class of triblock
copolymer of poly(ethylene)-poly(propylene)-poly(ethylene)),
as a drug delivery vectors. Pluronic PE6200 (PL6200) is selected
as one of the phase formers of aqueous biphasic system (ABS)
having in mind the amphiphilic nature of Pluronics which enables
good solubilization of hydrophobic molecules, their biocompatibility,
water solubility and complex mesophase behaviour. ABSs
are formed by combination of aqueous solutions of two polymers,
two salts or polymer/salt above certain concentrations with water
as the main constituent of both phases of ABS. In the quest for
more selective, performant and “greener” extraction technique of
PTL from natural matrices, a novel ABS comprised of a hydrophilic
ionic liquid (IL) - cholinium pyruvate (ChPyr) and PL6200
was investigated. In order to design selective Pluronic-mediated
purification process, (1) the ternary phase diagram was determinated
and characterised and (2) the partition of hydrophobic
PTL in this system was evaluated. A solution composed of 20
wt% of ChPyr + 30 wt% of PL6200 + 50 wt% of water with PTL
concentration of 2 mgml-1 led to high PTL extraction efficiency in
PL6200-rich phase (above 82%) with partition coefficient of 4.96.
The partition of PTL is mainly driven by its hydrophobic interaction
with poloxamer. For lower PL6200 concentrations in ABS,
formation of micelle particles was observed, what enabled solubilization
of PTL and its migration to hydrophilic IL-rich phase.
That decreased the PTL extraction efficiency toward PL6200-
rich phase. The obtained results showed that using cholinium-IL
/ Pluronic based ABS is promising alternative to volatile organic solvents that are nowdays used for extraction of PTL. Moreover,
using the Pluronic as constituent of ABS can provide the possibility
to simultaneously deal with low aqueous solubility of PTL by
forming the drug-loaded micelle particles and selective extraction
of active compound from real matrix.",
publisher = "Turkish Chemical Society",
journal = "XX Euroanalysis 2019 Conference, Abstracts and Proceedings",
title = "Controlling of the parthenolide partition using micelle structures of block copolymer in ionic liquid based aqueous biphasic system",
pages = "212-214",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5288"
}

Dimitrijević, A., Jocić, A., Marić, S., Zdolšek, N., Trtić-Petrović, T., Vraneš, M., Gadžurić, S., Arsenijević, J., Ražić, S., Tavares, A. P. M.,& Freire, M. G.. (2019). Controlling of the parthenolide partition using micelle structures of block copolymer in ionic liquid based aqueous biphasic system. in XX Euroanalysis 2019 Conference, Abstracts and Proceedings
Turkish Chemical Society., 212-214.
https://hdl.handle.net/21.15107/rcub_farfar_5288

Dimitrijević A, Jocić A, Marić S, Zdolšek N, Trtić-Petrović T, Vraneš M, Gadžurić S, Arsenijević J, Ražić S, Tavares APM, Freire MG. Controlling of the parthenolide partition using micelle structures of block copolymer in ionic liquid based aqueous biphasic system. in XX Euroanalysis 2019 Conference, Abstracts and Proceedings. 2019;:212-214.
https://hdl.handle.net/21.15107/rcub_farfar_5288 .

Dimitrijević, Aleksandra, Jocić, Ana, Marić, Slađana, Zdolšek, Nikola, Trtić-Petrović, Tatjana, Vraneš, Milan, Gadžurić, Slobodan, Arsenijević, Jelena, Ražić, Slavica, Tavares, Ana Paula M., Freire, Mara G., "Controlling of the parthenolide partition using micelle structures of block copolymer in ionic liquid based aqueous biphasic system" in XX Euroanalysis 2019 Conference, Abstracts and Proceedings (2019):212-214,
https://hdl.handle.net/21.15107/rcub_farfar_5288 .

TY  - JOUR
AU  - Bajuk-Bogdanovic, Danica
AU  - Holclajtner-Antunović, Ivanka
AU  - Jovanović, Zoran
AU  - Mravik, Željko
AU  - Krstić, Jugoslav
AU  - Uskoković-Marković, Snežana
AU  - Vujkovic, Milica
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3455
AB  - The synergistic effects between two Keggin-type heteropoly acids (HPAs) and carbon surface were examined and elucidated. An improved high rate capability (and potential high capacitor electrode for supercapacitors) of the hybrid materials, obtained by anchoring of α-dodecamolybdophosphoric (MoPA), α-dodecatungstophosphoric (WPA), and their mixture to activated carbon (AC), was achieved through the different mechanism of interaction. In order to elaborate this, a detailed analysis of AC-HPA composites has been performed by scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET) analysis, temperature-programmed desorption (TPD), Fourier-transform infrared spectroscopy (FTIR), micro Raman spectroscopy, and zeta potential measurements. The zeta potential measurements revealed positive charge of carbon surface thus indicating attractive interactions with negatively charged Keggin anion. The surface analysis has shown that WPA spontaneously reduces the carbon surface, while interaction with MoPA leads to its oxidation. As the consequence of the tailoring of the functional groups at carbon surface through HPAs’ action, the distortion of cyclic voltammograms (CVs) decreased in the following order: AC-MoPA, AC-MoPA-WPA, and AC-WPA. A prominent rectangular shape of AC-WPA, even at an extremely high scan rate of 400 mVs−1, was measured, which is rarely demonstrated for carbon-based composites. By applying the theory of electrode potentials, the HPA-AC synergistic effect was explained and discussed in terms of charge storage improvement of HPA-modified carbon.
PB  - Springer
T2  - Journal of Solid State Electrochemistry
T1  - Tailoring the electrochemical charge storage properties of carbonaceous support by redox properties of heteropoly acids: where does the synergy come from?
VL  - 23
IS  - 9
SP  - 2747
EP  - 2758
DO  - 10.1007/s10008-019-04369-4
ER  - 

@article{
author = "Bajuk-Bogdanovic, Danica and Holclajtner-Antunović, Ivanka and Jovanović, Zoran and Mravik, Željko and Krstić, Jugoslav and Uskoković-Marković, Snežana and Vujkovic, Milica",
year = "2019",
abstract = "The synergistic effects between two Keggin-type heteropoly acids (HPAs) and carbon surface were examined and elucidated. An improved high rate capability (and potential high capacitor electrode for supercapacitors) of the hybrid materials, obtained by anchoring of α-dodecamolybdophosphoric (MoPA), α-dodecatungstophosphoric (WPA), and their mixture to activated carbon (AC), was achieved through the different mechanism of interaction. In order to elaborate this, a detailed analysis of AC-HPA composites has been performed by scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET) analysis, temperature-programmed desorption (TPD), Fourier-transform infrared spectroscopy (FTIR), micro Raman spectroscopy, and zeta potential measurements. The zeta potential measurements revealed positive charge of carbon surface thus indicating attractive interactions with negatively charged Keggin anion. The surface analysis has shown that WPA spontaneously reduces the carbon surface, while interaction with MoPA leads to its oxidation. As the consequence of the tailoring of the functional groups at carbon surface through HPAs’ action, the distortion of cyclic voltammograms (CVs) decreased in the following order: AC-MoPA, AC-MoPA-WPA, and AC-WPA. A prominent rectangular shape of AC-WPA, even at an extremely high scan rate of 400 mVs−1, was measured, which is rarely demonstrated for carbon-based composites. By applying the theory of electrode potentials, the HPA-AC synergistic effect was explained and discussed in terms of charge storage improvement of HPA-modified carbon.",
publisher = "Springer",
journal = "Journal of Solid State Electrochemistry",
title = "Tailoring the electrochemical charge storage properties of carbonaceous support by redox properties of heteropoly acids: where does the synergy come from?",
volume = "23",
number = "9",
pages = "2747-2758",
doi = "10.1007/s10008-019-04369-4"
}

Bajuk-Bogdanovic, D., Holclajtner-Antunović, I., Jovanović, Z., Mravik, Ž., Krstić, J., Uskoković-Marković, S.,& Vujkovic, M.. (2019). Tailoring the electrochemical charge storage properties of carbonaceous support by redox properties of heteropoly acids: where does the synergy come from?. in Journal of Solid State Electrochemistry
Springer., 23(9), 2747-2758.
https://doi.org/10.1007/s10008-019-04369-4

Bajuk-Bogdanovic D, Holclajtner-Antunović I, Jovanović Z, Mravik Ž, Krstić J, Uskoković-Marković S, Vujkovic M. Tailoring the electrochemical charge storage properties of carbonaceous support by redox properties of heteropoly acids: where does the synergy come from?. in Journal of Solid State Electrochemistry. 2019;23(9):2747-2758.
doi:10.1007/s10008-019-04369-4 .

Bajuk-Bogdanovic, Danica, Holclajtner-Antunović, Ivanka, Jovanović, Zoran, Mravik, Željko, Krstić, Jugoslav, Uskoković-Marković, Snežana, Vujkovic, Milica, "Tailoring the electrochemical charge storage properties of carbonaceous support by redox properties of heteropoly acids: where does the synergy come from?" in Journal of Solid State Electrochemistry, 23, no. 9 (2019):2747-2758,
https://doi.org/10.1007/s10008-019-04369-4 . .