@article{
author = "Čakar, Mira and Popović, Gordana and Vladimirov, Sote",
year = "2004",
abstract = "A simple and reliable HPTLC method has been developed for simultaneous determination of antimycotics (bifonazole and econazole nitrate) and preservatives (methyl- and propylparaben) in medicinal creams. Chromatography was performed on silica gel plates with ethyl acetate-n-hexane-methanol-ammonia-diethylamine, 0.5 + 4 + 0.8 + 0.4 + 2 (v/v) as mobile phase. Chromatographic zones corresponding to spots of econazole nitrate, bifonazole, and parabens were scanned in reflectance/absorbance mode at lambda = 230, 250, and 300 nm, respectively. The method was successfully applied to simultaneous determination of the compounds in commercially available pharmaceuticals.",
publisher = "Springer Nature",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams",
volume = "17",
number = "3",
pages = "177-180",
doi = "10.1556/JPC.17.2004.3.4"
}