TY  - JOUR
AU  - Tomić, Ana
AU  - Božin, Biljana
AU  - Samojlik, Isidora
AU  - Milenković, Marina
AU  - Mimica-Dukić, Neda
AU  - Petrović, Silvana
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5235
AB  - The effects of essential oils isolated from mature fruits of Athamanta turbith ssp. hungarica (Borbás) Tutin
and A. turbith ssp. haynaldii (Borbás & Uechtr.) Tutin (Umbelliferae) on some liver biochemical parameters
in mice intoxicated with carbon tetrachloride were investigated. Pretreatment with both essential oils extenuated
the effects caused by carbon tetrachloride. In order to investigate in vitro antioxidant properties of the
oils, three methods were applied: scavenging of both 2,2-diphenyl-1-picrylhydrazyl (DPPH) and OH radicals,
as well as a test of inhibition of Fe2+/ascorbic-induced lipid peroxidation. Investigated essential oils exhibited
modest antioxidant capacity. Therefore, their infl uence on biochemical parameters in intoxicated animals might
be linked to the inhibition of enzymes (cytochrome P450 2E1) involved in metabolic activation of halomethanes.
PB  - John Wiley & Sons, Ltd.
T2  - Phytotherapy Research
T1  - Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties
VL  - 24
IS  - 5
SP  - 787
EP  - 790
DO  - 10.1002/ptr.3036
ER  - 

@article{
author = "Tomić, Ana and Božin, Biljana and Samojlik, Isidora and Milenković, Marina and Mimica-Dukić, Neda and Petrović, Silvana",
year = "2010",
abstract = "The effects of essential oils isolated from mature fruits of Athamanta turbith ssp. hungarica (Borbás) Tutin
and A. turbith ssp. haynaldii (Borbás & Uechtr.) Tutin (Umbelliferae) on some liver biochemical parameters
in mice intoxicated with carbon tetrachloride were investigated. Pretreatment with both essential oils extenuated
the effects caused by carbon tetrachloride. In order to investigate in vitro antioxidant properties of the
oils, three methods were applied: scavenging of both 2,2-diphenyl-1-picrylhydrazyl (DPPH) and OH radicals,
as well as a test of inhibition of Fe2+/ascorbic-induced lipid peroxidation. Investigated essential oils exhibited
modest antioxidant capacity. Therefore, their infl uence on biochemical parameters in intoxicated animals might
be linked to the inhibition of enzymes (cytochrome P450 2E1) involved in metabolic activation of halomethanes.",
publisher = "John Wiley & Sons, Ltd.",
journal = "Phytotherapy Research",
title = "Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties",
volume = "24",
number = "5",
pages = "787-790",
doi = "10.1002/ptr.3036"
}

Tomić, A., Božin, B., Samojlik, I., Milenković, M., Mimica-Dukić, N.,& Petrović, S.. (2010). Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties. in Phytotherapy Research
John Wiley & Sons, Ltd.., 24(5), 787-790.
https://doi.org/10.1002/ptr.3036

Tomić A, Božin B, Samojlik I, Milenković M, Mimica-Dukić N, Petrović S. Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties. in Phytotherapy Research. 2010;24(5):787-790.
doi:10.1002/ptr.3036 .

Tomić, Ana, Božin, Biljana, Samojlik, Isidora, Milenković, Marina, Mimica-Dukić, Neda, Petrović, Silvana, "Effects of Athamanta turbith Fruit Essential Oils on CCl4-induced Hepatic Failure in Mice and Their Antioxidant Properties" in Phytotherapy Research, 24, no. 5 (2010):787-790,
https://doi.org/10.1002/ptr.3036 . .