TY  - JOUR
AU  - Lupattelli, Angela
AU  - Spigset, Olav
AU  - Twigg, Michael J.
AU  - Zagorodnikova, Ksenia
AU  - Mardby, Ann-Charlotte
AU  - Moretti, Myla E.
AU  - Drozd, Mariola
AU  - Panchaud, Alice
AU  - Haemeen-Anttila, Katri
AU  - Rieutord, Andre
AU  - Juraski, R. Gjergja
AU  - Odalović, Marina
AU  - Kennedy, Debra
AU  - Rudolf, Gorazd
AU  - Juch, Herbert
AU  - Passier, Anneke
AU  - Bjoernsdottir, Ingunn
AU  - Nordeng, Hedvig
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2154
AB  - Objectives Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with medications use in pregnancy from a multinational perspective, with emphasis on type of medication utilised and indication for use. Design Cross-sectional, web-based study performed within the period from 1 October 2011 to 29 February 2012. Uniform collection of drug utilisation data was performed via an anonymous online questionnaire. Setting Multinational study in Europe (Western, Northern and Eastern), North and South America and Australia. Participants Pregnant women and new mothers with children less than 1year of age. Primary and secondary outcome measures Prevalence of and factors associated with medication use for acute/short-term illnesses, chronic/long-term disorders and over-the-counter (OTC) medication use. Results The study population included 9459 women, of which 81.2% reported use of at least one medication (prescribed or OTC) during pregnancy. Overall, OTC medication use occurred in 66.9% of the pregnancies, whereas 68.4% and 17% of women reported use of at least one medication for treatment of acute/short-term illnesses and chronic/long-term disorders, respectively. The extent of self-reported medicated illnesses and types of medication used by indication varied across regions, especially in relation to urinary tract infections, depression or OTC nasal sprays. Women with higher age or lower educational level, housewives or women with an unplanned pregnancy were those most often reporting use of medication for chronic/long-term disorders. Immigrant women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34 to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to 0.83) were less likely to report use of medication for chronic/long-term disorders during pregnancy than non-immigrants. Conclusions In this study, the majority of women in Europe, North America, South America and Australia used at least one medication during pregnancy. There was a substantial inter-region variability in the types of medication used.
PB  - BMJ PUBLISHING GROUP, LONDON
T2  - BMJ Open
T1  - Medication use in pregnancy: a cross-sectional, multinational web-based study
VL  - 4
IS  - 2
DO  - 10.1136/bmjopen-2013-004365
ER  - 

@article{
author = "Lupattelli, Angela and Spigset, Olav and Twigg, Michael J. and Zagorodnikova, Ksenia and Mardby, Ann-Charlotte and Moretti, Myla E. and Drozd, Mariola and Panchaud, Alice and Haemeen-Anttila, Katri and Rieutord, Andre and Juraski, R. Gjergja and Odalović, Marina and Kennedy, Debra and Rudolf, Gorazd and Juch, Herbert and Passier, Anneke and Bjoernsdottir, Ingunn and Nordeng, Hedvig",
year = "2014",
abstract = "Objectives Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with medications use in pregnancy from a multinational perspective, with emphasis on type of medication utilised and indication for use. Design Cross-sectional, web-based study performed within the period from 1 October 2011 to 29 February 2012. Uniform collection of drug utilisation data was performed via an anonymous online questionnaire. Setting Multinational study in Europe (Western, Northern and Eastern), North and South America and Australia. Participants Pregnant women and new mothers with children less than 1year of age. Primary and secondary outcome measures Prevalence of and factors associated with medication use for acute/short-term illnesses, chronic/long-term disorders and over-the-counter (OTC) medication use. Results The study population included 9459 women, of which 81.2% reported use of at least one medication (prescribed or OTC) during pregnancy. Overall, OTC medication use occurred in 66.9% of the pregnancies, whereas 68.4% and 17% of women reported use of at least one medication for treatment of acute/short-term illnesses and chronic/long-term disorders, respectively. The extent of self-reported medicated illnesses and types of medication used by indication varied across regions, especially in relation to urinary tract infections, depression or OTC nasal sprays. Women with higher age or lower educational level, housewives or women with an unplanned pregnancy were those most often reporting use of medication for chronic/long-term disorders. Immigrant women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34 to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to 0.83) were less likely to report use of medication for chronic/long-term disorders during pregnancy than non-immigrants. Conclusions In this study, the majority of women in Europe, North America, South America and Australia used at least one medication during pregnancy. There was a substantial inter-region variability in the types of medication used.",
publisher = "BMJ PUBLISHING GROUP, LONDON",
journal = "BMJ Open",
title = "Medication use in pregnancy: a cross-sectional, multinational web-based study",
volume = "4",
number = "2",
doi = "10.1136/bmjopen-2013-004365"
}

Lupattelli, A., Spigset, O., Twigg, M. J., Zagorodnikova, K., Mardby, A., Moretti, M. E., Drozd, M., Panchaud, A., Haemeen-Anttila, K., Rieutord, A., Juraski, R. G., Odalović, M., Kennedy, D., Rudolf, G., Juch, H., Passier, A., Bjoernsdottir, I.,& Nordeng, H.. (2014). Medication use in pregnancy: a cross-sectional, multinational web-based study. in BMJ Open
BMJ PUBLISHING GROUP, LONDON., 4(2).
https://doi.org/10.1136/bmjopen-2013-004365

Lupattelli A, Spigset O, Twigg MJ, Zagorodnikova K, Mardby A, Moretti ME, Drozd M, Panchaud A, Haemeen-Anttila K, Rieutord A, Juraski RG, Odalović M, Kennedy D, Rudolf G, Juch H, Passier A, Bjoernsdottir I, Nordeng H. Medication use in pregnancy: a cross-sectional, multinational web-based study. in BMJ Open. 2014;4(2).
doi:10.1136/bmjopen-2013-004365 .

Lupattelli, Angela, Spigset, Olav, Twigg, Michael J., Zagorodnikova, Ksenia, Mardby, Ann-Charlotte, Moretti, Myla E., Drozd, Mariola, Panchaud, Alice, Haemeen-Anttila, Katri, Rieutord, Andre, Juraski, R. Gjergja, Odalović, Marina, Kennedy, Debra, Rudolf, Gorazd, Juch, Herbert, Passier, Anneke, Bjoernsdottir, Ingunn, Nordeng, Hedvig, "Medication use in pregnancy: a cross-sectional, multinational web-based study" in BMJ Open, 4, no. 2 (2014),
https://doi.org/10.1136/bmjopen-2013-004365 . .