Претраживање
Приказ резултата 11-20 од 20
From co-processing by melt granulation towards direct compression of high ibuprofen loaded formulations
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Direct compression, as the simplest and therefore
preferable method of tableting, is often hindered by poor
flow and compaction properties of the active
pharmaceutical ingredient (API). Tableting by direct
compression ...
Characterization of chitosan/xanthan gum polyelectrolyte complexes as carriers for ibuprofen: influence of drug encapsulation procedure on complex formation
(Macedonian Pharmaceutical AssociationFaculty of Pharmacy, Ss Cyril and Methodius University in Skopje, 2020)
Introduction
Ibuprofen (IBU) is commonly used non-steroidal
anti-inflammatory drug. It is a weak acid (pKa ~4.5)
with low pH dependent aqueous solubility (46
μg/mL at pH 1.5 and ˃300 μg/mL at pH˃7, at 25
°C). The most ...
Selenium nanoparticles render pandrug-resistant Acinetobacter baumannii susceptible to colistin
(Macedonian Pharmaceutical Association, 2022)
Colistin is used as a “last resort” drug in the treatment
of carbapenem-resistant Acinetobacter baumannii
infections. Though not the most convenient option due to
the serious side effects, this antibiotic can be very ...
Digital light processing 3D printing of Hydrochlorothiazide with modified release
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Additive manufacturing also known as 3D printing
gains more attention in scientific research due to its great
advantages in simple and fast producing custom-designed
products. 3D models created with computer-aided ...
Functional characterization of microcrystalline cellulose obtained from the crop residues
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Crop residues (CR) are usually burned in the field,
which causes air pollution, contributes to global warming,
hinders nutrient recycling, and negatively affects soil
microbes through overheating and carbon loss. There ...
A text mining study on the utility of physiologically based pharmacokinetic/biopharmaceutics modeling (PBPK/PBBM) in formulation development
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Physiologically based pharmacokinetic (PBPK)
modeling is an evolving tool that has a profound impact on
drug discovery and formulation development processes. A
major advantage of PBPK models is that they have the
ability ...
Assessment of mucoadhesive buccal tablets with propranolol hydrochloride using principal component analysis
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Multivariate analysis methods are a set of statistical
techniques that allow multiple variables to be tested
simultaneously. This makes them ideal for studying
relationships in large complex datasets. Pharmaceutical
products ...
Selective laser sintering (SLS) 3D printing process: Influence of model design on the properties of zolpidem tartrate tablets
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Three-dimensional printing (3DP) is an innovative
additive manufacturing technology in the field of
pharmaceuticals that has the potential to provide small
batches of patient-tailored medicines (Wang et al., 2021).
One ...
Fun-shaped oral dosage forms for the pediatric population fabricated by digital light processing (DLP) 3D printing technique
(Macedonian Pharmaceutical AssociationFaculty of Pharmacy, Ss Cyril and Methodius University in Skopje, 2022)
Introduction Three-dimensional (3D) printing as an innovative technology in the field of drug manufacturing has attracted a lot of attention from the scientific and professional public in recent years. Classified into seven ...
The influence of directly compressible fillers/diluents on selected compact properties and drug dissolution: a case study of rivaroxaban
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Direct compression represents a favorable tablet
manufacturing method. However, obtaining satisfactory
mechanical properties of the compacts and drug dissolution
remains a challenge in formulation development,
particularly ...