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Pharmacokinetic characterization, benefits and barriers of subcutaneous administration of monoclonal antibodies in oncology
(SAGE Publications Ltd, 2023)
Objective: Therapeutic monoclonal antibodies in oncology are slowly becoming the dominant treatment option for many different cancer types. The main route of administration, infusion, requires extensive product preparations, ...
Spectrophotometric and HPLC determination of fleroxacin in tablets
(Govi-Verlag Pharmazeutischer Verlag Gmbh, Eschborn, 2001)
Abstract
The paper describes and compares spectrophotometric and HPLC determination of fleroxacin in commercial tablets. The optimum conditions for spectrophotometric assay were found to be at pH < 3.5 (0.1 M HCl) at a ...
The effect of nasal douching by hypertonic 2.3% sea water with algae extracts on the concentration of epidermal growth factor, transforming growth factor-α and interleukin-8 in nasal secretions of patients with nasal polyposis following endoscopic surgical treatment
(Cambridge University Press, 2023)
Objective. To investigate epidermal growth factor (EGF), transforming growth factor (TGF)- a and interleukin (IL)-8 production in nasal mucosa irrigated with hypertonic 2.3% solution with algae extracts, in comparison to ...
Upregulation of peripheral blood mononuclear cells resistin gene expression in severe obstructive sleep apnea and obstructive sleep apnea with coexisting type 2 diabetes mellitus
(Springer Nature, 2023)
Purpose: Obstructive sleep apnea (OSA) is characterised by increased systemic inflammation, and is often accompanied with type 2 diabetes mellitus (T2DM) and cardiovascular disease. The aim of this investigation was to ...
A cross-sectional study comparing emotional intelligence and perceived stress amongst community pharmacists delivering and not delivering a new service
(Springer Nature, 2023)
Background: Community pharmacists contribute substantially to public health and person-centred care. Emotional intelligence (EI) may help health professionals better engage with patients, handle stress in challenging ...
Correlation of Short Leukocyte Telomeres and Oxidative Stress with the Presence and Severity of Lung Cancer Explored by Principal Component Analysis
(Charles University, Czech Republic, 2023)
Lung cancer (LC) is the second most common malignancy and leading cause of cancer death. The potential "culprit" for local and systemic telomere shortening in LC patients is oxidative stress. We investigated the correlation ...
Protolytic equilibria of ACE inhibitors in micellar solution of nonionic surfactant Brij 35
(Springer, 2023)
The acid–base equilibria of six ACE inhibitors (ACEIs), captopril, cilazapril, enalapril, lisinopril, quinapril, and rami-
pril, were investigated in the presence of micelles of nonionic surfactant Brij 35. The pKa values ...
Antimicrobial utilization and resistance in Pseudomonas aeruginosa using segmented regression analysis: a comparative study between Serbia and eight European Countries
(Springer, 2023)
Background In Europe, Serbia occupies a high position in antibiotic utilization and antimicrobial resistance (AMR). Aim The aim was to analyse utilization trends of meropenem, ceftazidime, aminoglycosides, piperacillin/tazobactam ...
The influence of Klotho protein and prooxidant–antioxidant balance combination on the mortality of HD patients
(Springer Science and Business Media B.V., 2024)
Purpose: End-stage renal disease patients on chronic hemodialysis (HD) have a shortened life expectancy compared to the general population. The aim of this study was to evaluate a possible link between three new and emerging ...