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Acidosis, cognitive dysfunction and motor impairments in patients with kidney disease
(Oxford University Press, 2022)
Metabolic acidosis, defined as a plasma or serum bicarbonate concentration <22 mmol/L, is a frequent consequence of chronic kidney disease (CKD) and occurs in ~10-30% of patients with advanced stages of CKD. Likewise, in ...
Albuminuria as a risk factor for mild cognitive impairment and dementia-what is the evidence?
(Oxford University Press, 2022)
Kidney dysfunction can profoundly influence many organ systems, and recent evidence suggests a potential role for increased albuminuria in the development of mild cognitive impairment (MCI) or dementia. Epidemiological ...
Brain dysfunction in tubular and tubulointerstitial kidney diseases
(Oxford University Press, 2022)
Kidney function has two important elements: glomerular filtration and tubular function (secretion and reabsorption). A persistent decrease in glomerular filtration rate (GFR), with or without proteinuria, is diagnostic of ...
The NOAEL Equivalent of Environmental Cadmium Exposure Associated with GFR Reduction and Chronic Kidney Disease
(MDPI, 2022)
Cadmium (Cd) is a highly toxic metal pollutant present in virtually all food types. Health guidance values were established to safeguard against excessive dietary Cd exposure. The derivation of such health guidance figures ...