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Application of miscibility analysis and determination of Soluplus solubility map for development of carvedilol-loaded nanofibers
(Elsevier, 2017)
Electrospinning was used to produce carvedilol-loaded Soluplus polymer nanofibers using a systematic approach. Miscibility between drug and polymer was determined through calculation of the interaction parameter, chi, and ...
Application of miscibility analysis and determination of Soluplus solubility map for development of carvedilol-loaded nanofibers
(Elsevier Science BV, Amsterdam, 2017)
Electrospinning was used to produce carvedilol-loaded Soluplus polymer nanofibers using a systematic approach. Miscibility between drug and polymer was determined through calculation of the interaction parameter, chi, and ...
Potential application of low molecular weight excipients for amorphization and dissolution enhancement of carvedilol
(Elsevier B.V., 2021)
In this study, four low molecular weight (LMW) excipients, tryptophan (TRY), phenylalanine (PHE), lysine (LYS) and saccharin (SAC) were evaluated as co-formers to generate co-amorphous systems (CAMS) by ball milling with ...