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Chemometrical approach in fosinopril-sodium and its degradation product fosinoprilat analysis
(Springer Heidelberg, Heidelberg, 2004)
In this paper the experimental design has been applied to define the optimum chromatographic conditions for the separation of Fosinopril sodium and its degradation product, fosinoprilat. Fosinopril is a prodrug and after ...
Simultaneous Analysis of Irbesartan and Hydrochlorothiazide: An Improved HPLC Method with the Aid of a Chemometric Protocol
(MDPI, Basel, 2012)
Experimental design method was used for HPLC determination of irbesartan and hydrochlorothiazide in combined dosage forms. The traditional approach for optimization of experiments is time-consuming, involves a large number ...
Physicochemical Factors Governing the Partition of Pramipexole and Its Five Impurities in Microemulsion Liquid Chromatographic Systems
(Soc Brasileira Quimica, Sao Paulo, 2012)
Microemulsions when used as mobile phases represent a very powerful chromatographic tool due to their polyphase structure. The aim of this study was to investigate the influence of the mobile phase composition and resulting ...
Statistical optimization applied to simultaneous determination of maprotiline, desipramine, and moclobemide by capillary zone electrophoresis
(Springer Wien, Wien, 2008)
A method of Capillary Zone Electrophoresis (CZE) for separation of three most-frequently prescribed antidepressants in the market: maprotiline, desipramine, and moclobemide was developed. The proposed method is fully ...
Application of mathematical modeling for the development and optimization formulation with bioactive copper complex
(Taylor & Francis Ltd, Abingdon, 2013)
New formulation for treatment a copper deficiency in human organism was developed and optimized by application of mathematical modeling. This formulation contained copper (II) complex with polysaccharide pullulan, as active ...
Towards satisfying performance of an O/W cosmetic emulsion: screening of reformulation factors on textural and rheological properties using general experimental design
(Wiley, Hoboken, 2017)
OBJECTIVE: Consumers' demand for improved products' performance, alongside with the obligation of meeting the safety and efficacy goals, presents a key reason for the reformulation, as well as a challenging task for ...