Antioxidant and antimicrobial activity of Cynara cardunculus extracts
Authorized Users Only
2008
Authors
Kukić, Jelena
Popović, Višnja
Petrović, Silvana

Mucaji, Pavel
Ćirić, Ana D.

Stojković, Dejan

Soković, Marina

Article (Published version)

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The whole, fresh involucral bracts of cardoon, Cynara cardunculus L. (Compositae), were extracted with EtOH and an aqueous suspension of the obtained EtOH extract was partitioned successively with CHCl3, EtOAc and n-BuOH, leaving a residual water extract. All obtained extracts were evaluated for their antioxidant and antimicrobial properties. The antioxidant potential was evaluated using following in vitro methods: FRAP (ferric reducing antioxidant power) assay, and scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. Antimicrobial activity was estimated using a microdilution technique against food-borne, mycotoxin producers and human pathogenic bacteria and micromycetes. The following bacteria were tested: Salmonella typhimurium, Escherichia coli, Bacillus subtilis, Staphylococcus epidermidis, Staphylococcus aureus, as well as micromycetes: Aspergillus niger, Aspergillus ochraceus, Aspergillus flavus, Penicillium ochrochloron, Penicillium funiculosum, Trichoderma viride, Fusari...um tricinctum and Alternaria alternata. Results showed that all extracts possessed concentration-dependent antioxidant activity. In biological assays, C. cardunculus extracts showed antimicrobial activity comparable with standard antibiotics.
Keywords:
Cynara cardunculus / involucral bracts / antioxidant activity / FRAP / DPPH / antimicrobial activitySource:
Food Chemistry, 2008, 107, 2, 861-868Publisher:
- Elsevier Sci Ltd, Oxford
Funding / projects:
- Ispitivanje lekovitog potencijala biljaka: morfološka, hemijska i farmakološka karakterizacija (RS-143012)
- Taksonomska, biohemijska i molekularna istraživanja gljiva i biološki aktivnih supstanci (RS-143041)
Note:
- Peer-reviewed manuscript: http://farfar.pharmacy.bg.ac.rs/handle/123456789/3548
DOI: 10.1016/j.foodchem.2007.09.005
ISSN: 0308-8146
WoS: 000251760400035
Scopus: 2-s2.0-36248960107
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Institution/Community
PharmacyTY - JOUR AU - Kukić, Jelena AU - Popović, Višnja AU - Petrović, Silvana AU - Mucaji, Pavel AU - Ćirić, Ana D. AU - Stojković, Dejan AU - Soković, Marina PY - 2008 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1049 AB - The whole, fresh involucral bracts of cardoon, Cynara cardunculus L. (Compositae), were extracted with EtOH and an aqueous suspension of the obtained EtOH extract was partitioned successively with CHCl3, EtOAc and n-BuOH, leaving a residual water extract. All obtained extracts were evaluated for their antioxidant and antimicrobial properties. The antioxidant potential was evaluated using following in vitro methods: FRAP (ferric reducing antioxidant power) assay, and scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. Antimicrobial activity was estimated using a microdilution technique against food-borne, mycotoxin producers and human pathogenic bacteria and micromycetes. The following bacteria were tested: Salmonella typhimurium, Escherichia coli, Bacillus subtilis, Staphylococcus epidermidis, Staphylococcus aureus, as well as micromycetes: Aspergillus niger, Aspergillus ochraceus, Aspergillus flavus, Penicillium ochrochloron, Penicillium funiculosum, Trichoderma viride, Fusarium tricinctum and Alternaria alternata. Results showed that all extracts possessed concentration-dependent antioxidant activity. In biological assays, C. cardunculus extracts showed antimicrobial activity comparable with standard antibiotics. PB - Elsevier Sci Ltd, Oxford T2 - Food Chemistry T1 - Antioxidant and antimicrobial activity of Cynara cardunculus extracts VL - 107 IS - 2 SP - 861 EP - 868 DO - 10.1016/j.foodchem.2007.09.005 ER -
@article{ author = "Kukić, Jelena and Popović, Višnja and Petrović, Silvana and Mucaji, Pavel and Ćirić, Ana D. and Stojković, Dejan and Soković, Marina", year = "2008", abstract = "The whole, fresh involucral bracts of cardoon, Cynara cardunculus L. (Compositae), were extracted with EtOH and an aqueous suspension of the obtained EtOH extract was partitioned successively with CHCl3, EtOAc and n-BuOH, leaving a residual water extract. All obtained extracts were evaluated for their antioxidant and antimicrobial properties. The antioxidant potential was evaluated using following in vitro methods: FRAP (ferric reducing antioxidant power) assay, and scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. Antimicrobial activity was estimated using a microdilution technique against food-borne, mycotoxin producers and human pathogenic bacteria and micromycetes. The following bacteria were tested: Salmonella typhimurium, Escherichia coli, Bacillus subtilis, Staphylococcus epidermidis, Staphylococcus aureus, as well as micromycetes: Aspergillus niger, Aspergillus ochraceus, Aspergillus flavus, Penicillium ochrochloron, Penicillium funiculosum, Trichoderma viride, Fusarium tricinctum and Alternaria alternata. Results showed that all extracts possessed concentration-dependent antioxidant activity. In biological assays, C. cardunculus extracts showed antimicrobial activity comparable with standard antibiotics.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Food Chemistry", title = "Antioxidant and antimicrobial activity of Cynara cardunculus extracts", volume = "107", number = "2", pages = "861-868", doi = "10.1016/j.foodchem.2007.09.005" }
Kukić, J., Popović, V., Petrović, S., Mucaji, P., Ćirić, A. D., Stojković, D.,& Soković, M.. (2008). Antioxidant and antimicrobial activity of Cynara cardunculus extracts. in Food Chemistry Elsevier Sci Ltd, Oxford., 107(2), 861-868. https://doi.org/10.1016/j.foodchem.2007.09.005
Kukić J, Popović V, Petrović S, Mucaji P, Ćirić AD, Stojković D, Soković M. Antioxidant and antimicrobial activity of Cynara cardunculus extracts. in Food Chemistry. 2008;107(2):861-868. doi:10.1016/j.foodchem.2007.09.005 .
Kukić, Jelena, Popović, Višnja, Petrović, Silvana, Mucaji, Pavel, Ćirić, Ana D., Stojković, Dejan, Soković, Marina, "Antioxidant and antimicrobial activity of Cynara cardunculus extracts" in Food Chemistry, 107, no. 2 (2008):861-868, https://doi.org/10.1016/j.foodchem.2007.09.005 . .