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dc.creatorCerović, Aleksandra
dc.creatorMiletić, Ivanka
dc.creatorBlagojević, Duško
dc.creatorŠobajić, Slađana
dc.creatorVasiljevska, Milijana
dc.creatorPoznanić, Milica
dc.creatorRadusinović, M.
dc.date.accessioned2019-09-02T11:13:22Z
dc.date.available2019-09-02T11:13:22Z
dc.date.issued2008
dc.identifier.issn0001-7213
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1069
dc.description.abstractThis study examined the influence of low, adequate and high dietary zinc intake on the growth and metabolic interactions between zinc, copper and iron in different Mongolian gerbil (Meriones unguiculatus) tissues. Animals were fed a basal diet (for 3 wk) containing a low-zinc level (8 mg/ kg diet, LZ-group), adequate zinc level (25 mg/kg diet, AZ-group) and saturated zinc level (38 mg/ kg diet, SZ-group). After comparing the body weight of gerbils, the present study demonstrated that the LZ-group (51.68 g +/- 3.35) showed growth retardation, contrary to the AZ- and SZ-groups (58.03 g +/- 2.18 and 62.35 g +/- 2.04, respectively). Concentrations of zinc in the liver, kidneys and testes in the LZ-group (41.28, 19.58, 22.55 mg/kg, respectively) were significantly lower than in the AZ-group (57.27, 23.73, 28.79 mg/kg, respectively) and the SZ-group (73.06, 30.07, 34.52 mg/kg, respectively). Results also showed that copper and iron concentrations in the kidney, heart and liver were significantly higher in the LZ-group (Cu 11.45, 7.01, 7.95 mg/kg; Fe 116.19, 126.07, 299.47 mg/kg) than in the AZ-group (Cu 8.72, 5.6, 6.5 mg/kg; Fe 97.27, 97.27, 250.25 mg/kg) and the SZ-group (Cu 6.48, 4.15, 4.8 mg/kg; Fe 74.95, 77.95, 200.27 mg/kg). There was an increase of testis copper concentration in the LZ-group (4.9 mg/kg) compared to the AZ- and SZ-groups (3.99 and 3.05 mg/kg, respectively), and there was no significant difference in testis iron concentration between animals in different diet groups. These results showed that a low-zinc diet had negative effects on growth and the concentration of zinc in the kidneys, liver and testes. This also affected homeostasis of copper and iron by increasing its distribution in the kidneys, liver and heart tissue. However, in testes only copper concentration was increased.en
dc.publisherVeterinarni A Farmaceuticka Univerzita Brno, Brno
dc.rightsopenAccess
dc.sourceActa Veterinaria Brno
dc.subjecthomeostasisen
dc.subjectZnen
dc.subjectCuen
dc.subjectFeen
dc.subjectgrowthen
dc.subjectkidneyen
dc.subjectliveren
dc.subjectheart and testis tissuesen
dc.titleEffects of low, adequate and high dietary zinc intake on metabolic interactions between zinc, copper and iron in different mongolian gerbil tissuesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractПознанић, Милица; Шобајић, Слађана; Радусиновић, М.; Васиљевска, Милијана; Благојевић, Душко; Милетић, Иванка; Церовић, Aлександра;
dc.citation.volume77
dc.citation.issue1
dc.citation.spage17
dc.citation.epage23
dc.citation.other77(1): 17-23
dc.citation.rankM23
dc.identifier.wos000255001500003
dc.identifier.doi10.2754/avb200877010017
dc.identifier.scopus2-s2.0-42449119354
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/55/1067.pdf
dc.identifier.rcubconv_1983
dc.type.versionpublishedVersion


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