Stereoselective synthesis of chiral beta(2,3)-disubstituted-beta-amino acid derivatives using Pd/In transmetallation cascade processes

Grigg, Ronald; Blacker, John; Kilner, Colin; McCaffrey, Shaun; Savić, Vladimir; Sridharan, Visuvanathar

doi:10.1016/j.tet.2008.06.037

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2008

Authors

Grigg, Ronald
Blacker, John
Kilner, Colin
McCaffrey, Shaun
Savić, Vladimir

Sridharan, Visuvanathar

Article (Published version)

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Abstract

A new, highly efficient synthesis of chiral beta(2.3)-disubstituted-beta-amino acid derivatives has been developed, based on an allylation procedure employing allene and a catalytic Pd/In bimetallic process.

Source:
Tetrahedron Letters, 2008, 64, 35, 8177-8181

Publisher:

Pergamon-Elsevier Science Ltd, Oxford

Projects:

Leeds University
EPSRC
Avecia and the Serbian Ministry of Science

DOI: 10.1016/j.tet.2008.06.037

ISSN: 0040-4020

WoS: 000258411600021

Scopus: 2-s2.0-47149115851

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