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Chemical composition and antimicrobial activity of Thymus pannonicus All. (Lamiaceae) essential oil

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2008
1114.pdf (790.9Kb)
Authors
Maksimović, Zoran
Milenković, Marina
Božić, Dragana
Ristić, Mihailo
Article (Published version)
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Abstract
This paper presents the results of a study on chemical composition and antimicrobial activity of Thymus pannonicus All. ( Lamiaceae) essential oil from Vojvodina province ( north of Serbia). The investigated oil was hydrodistilled from a flowering plant and analysed by GC and GC- MS. Fifty- three constituents were identified (> 97% of total oil), with geranial ( 41.42%, w/ w) and neral ( 29.61%, w/ w) as the most prominent. The antimicrobial activity of the oil was evaluated using agar disc diffusion and broth microdilution method against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, Escherichia coli, two strains of Klebsiella pneumoniae and two strains of Candida albicans. The essential oil exhibited antimicrobial activity to varying degrees against all tested strains. The maximum activity of T. pannonicus oil was observed against E. coli, S. aureus and both tested strains of C. albicans ( MIC = 50 mu l/ ml, each). Moderate activity was observed against P. aeru...ginosa and one of the tested strains of K. pneumoniae ( MIC = 200 mu l/ ml), while E. faecalis and the other strain of K. pneumoniae expressed a higher degree of resistance ( MIC > 200 mu l/ ml). This study confirms that essential oil of T. pannonicus possesses remarkable in vitro antimicrobial activity against several medicinally important pathogens. This is attributable to lemon- scented citral, a mixture of geranial and neral, which has well- documented antimicrobial activity against a range of bacteria and fungi.

Keywords:
thymus pannonicus / essential oil composition / antimicrobial activity / geranial / neral
Source:
Central European Journal of Biology, 2008, 3, 2, 149-154
Publisher:
  • Versita, Warsaw
Funding / projects:
  • Ispitivanje lekovitog potencijala biljaka: morfološka, hemijska i farmakološka karakterizacija (RS-143012)

DOI: 10.2478/s11535-008-0013-x

ISSN: 1895-104X

WoS: 000254756200006

Scopus: 2-s2.0-43349085449
[ Google Scholar ]
37
33
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/1116
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Maksimović, Zoran
AU  - Milenković, Marina
AU  - Božić, Dragana
AU  - Ristić, Mihailo
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1116
AB  - This paper presents the results of a study on chemical composition and antimicrobial activity of Thymus pannonicus All. ( Lamiaceae) essential oil from Vojvodina province ( north of Serbia). The investigated oil was hydrodistilled from a flowering plant and analysed by GC and GC- MS. Fifty- three constituents were identified (> 97% of total oil), with geranial ( 41.42%, w/ w) and neral ( 29.61%, w/ w) as the most prominent. The antimicrobial activity of the oil was evaluated using agar disc diffusion and broth microdilution method against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, Escherichia coli, two strains of Klebsiella pneumoniae and two strains of Candida albicans. The essential oil exhibited antimicrobial activity to varying degrees against all tested strains. The maximum activity of T. pannonicus oil was observed against E. coli, S. aureus and both tested strains of C. albicans ( MIC = 50 mu l/ ml, each). Moderate activity was observed against P. aeruginosa and one of the tested strains of K. pneumoniae ( MIC = 200 mu l/ ml), while E. faecalis and the other strain of K. pneumoniae expressed a higher degree of resistance ( MIC > 200 mu l/ ml). This study confirms that essential oil of T. pannonicus possesses remarkable in vitro antimicrobial activity against several medicinally important pathogens. This is attributable to lemon- scented citral, a mixture of geranial and neral, which has well- documented antimicrobial activity against a range of bacteria and fungi.
PB  - Versita, Warsaw
T2  - Central European Journal of Biology
T1  - Chemical composition and antimicrobial activity of Thymus pannonicus All. (Lamiaceae) essential oil
VL  - 3
IS  - 2
SP  - 149
EP  - 154
DO  - 10.2478/s11535-008-0013-x
ER  - 
@article{
author = "Maksimović, Zoran and Milenković, Marina and Božić, Dragana and Ristić, Mihailo",
year = "2008",
abstract = "This paper presents the results of a study on chemical composition and antimicrobial activity of Thymus pannonicus All. ( Lamiaceae) essential oil from Vojvodina province ( north of Serbia). The investigated oil was hydrodistilled from a flowering plant and analysed by GC and GC- MS. Fifty- three constituents were identified (> 97% of total oil), with geranial ( 41.42%, w/ w) and neral ( 29.61%, w/ w) as the most prominent. The antimicrobial activity of the oil was evaluated using agar disc diffusion and broth microdilution method against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, Escherichia coli, two strains of Klebsiella pneumoniae and two strains of Candida albicans. The essential oil exhibited antimicrobial activity to varying degrees against all tested strains. The maximum activity of T. pannonicus oil was observed against E. coli, S. aureus and both tested strains of C. albicans ( MIC = 50 mu l/ ml, each). Moderate activity was observed against P. aeruginosa and one of the tested strains of K. pneumoniae ( MIC = 200 mu l/ ml), while E. faecalis and the other strain of K. pneumoniae expressed a higher degree of resistance ( MIC > 200 mu l/ ml). This study confirms that essential oil of T. pannonicus possesses remarkable in vitro antimicrobial activity against several medicinally important pathogens. This is attributable to lemon- scented citral, a mixture of geranial and neral, which has well- documented antimicrobial activity against a range of bacteria and fungi.",
publisher = "Versita, Warsaw",
journal = "Central European Journal of Biology",
title = "Chemical composition and antimicrobial activity of Thymus pannonicus All. (Lamiaceae) essential oil",
volume = "3",
number = "2",
pages = "149-154",
doi = "10.2478/s11535-008-0013-x"
}
Maksimović, Z., Milenković, M., Božić, D.,& Ristić, M.. (2008). Chemical composition and antimicrobial activity of Thymus pannonicus All. (Lamiaceae) essential oil. in Central European Journal of Biology
Versita, Warsaw., 3(2), 149-154.
https://doi.org/10.2478/s11535-008-0013-x
Maksimović Z, Milenković M, Božić D, Ristić M. Chemical composition and antimicrobial activity of Thymus pannonicus All. (Lamiaceae) essential oil. in Central European Journal of Biology. 2008;3(2):149-154.
doi:10.2478/s11535-008-0013-x .
Maksimović, Zoran, Milenković, Marina, Božić, Dragana, Ristić, Mihailo, "Chemical composition and antimicrobial activity of Thymus pannonicus All. (Lamiaceae) essential oil" in Central European Journal of Biology, 3, no. 2 (2008):149-154,
https://doi.org/10.2478/s11535-008-0013-x . .

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