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Nova grupa antimikrobnih lekova - hemija glicilciklina

dc.creatorAgbaba, Danica
dc.creatorMarković, Bojan
dc.date.accessioned2019-09-02T11:14:58Z
dc.date.available2019-09-02T11:14:58Z
dc.date.issued2008
dc.identifier.issn0004-1963
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1130
dc.description.abstractHuman and veterinary medicines, since the late forties of the 20th century, have increasingly used tetracyclines as broad spectrum antibiotics. The wide and long-lasting usage of all antibiotics, including tetracyclines, accordingly causes a widespread microbial resistance. At the beginning of the nineties, the synthesis of a new antibiotics' group, including tetracyclic structure showing more active antibacterial potency and widespread spectrum activity on the existing resistant microorganisms' forms, have been reported and called glycylcyclines. The group development, its chemistry and the first launched tigecycline properties will be shown in this paper.en
dc.description.abstractHumana i veterinarska medicina, s kraja četrdesetih godina prošlog veka, je koristila tetracikline kao antibiotike širokog spektra dejstva. Obimna i duga upotreba svih antibiotika, uključujući i tetracikline, dovela je do pojave porasta rezistencije. Početkom devedesetih godina, objavljena je sinteza nove grupe antibiotika tetraciklične strukture, te je grupa koja je pokazala najjaču antimikrobnu aktivnost, najširi spektar dejstva na postojeće rezistentne forme mikroorganizama, nazvana glicilciklini. Razvoj ove grupe antibiotika, kao i hemija i osobine prvog registrovanog tigeciklina, prikazane su u ovom radu.sr
dc.publisherSavez farmaceutskih udruženja Srbije, Beograd
dc.rightsopenAccess
dc.sourceArhiv za farmaciju
dc.titleThe new group of antimicrobial drugs: Chemistry of glycylcyclinesen
dc.titleNova grupa antimikrobnih lekova - hemija glicilciklinasr
dc.typearticle
dc.rights.licenseBY-SA
dcterms.abstractМарковић, Бојан; Aгбаба, Даница; Нова група антимикробних лекова - хемија глицилциклина; Нова група антимикробних лекова - хемија глицилциклина;
dc.citation.volume58
dc.citation.issue1
dc.citation.spage1
dc.citation.epage8
dc.citation.other58(1): 1-8
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/99/1128.pdf
dc.identifier.rcubconv_367
dc.type.versionpublishedVersion


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