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dc.creatorMilinković, Neda
dc.creatorMajkić-Singh, Nada
dc.creatorMirković, Duško
dc.creatorBeletić, Anđelo
dc.creatorPejanović, Svetlana D.
dc.creatorVujanić, Svetlana T.
dc.date.accessioned2019-09-02T11:16:37Z
dc.date.available2019-09-02T11:16:37Z
dc.date.issued2009
dc.identifier.issn1433-6510
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/1189
dc.description.abstractDeficient serum 25-hydroxyvitamin D [25(OH)D] may contribute to the impaired bone turnover of end stage renal disease patients. In 112 hemodialysed patients we analysed the relation between 25(OH)D and bone alkaline phosphatase (BALP), beta-CrossLaps (beta-CTx) and iPTH. We analysed parameters according to the manufacturers' instructions. We found potentially significant vitamin D deficiency: 71% of patients had 25(OH)D levels below 50 nmol/L. In patients with iPTH below 150 pg/mL (n = 57), we observed significantly low 25(OH) (p lt 0.01). In addition, patients with iPTH above 300 pg/mL had higher BALP levels (p lt 0.05). There were negative correlations between serum 25(OH)D and both BALP and iPTH (r = -0.225, p lt 0.05 and r = -0.331, p lt 0.05). Beta-CTx levels were significantly higher in patients who did not receive vitamin D supplementation (p lt 0.01). In addition, reduced BALP and iPTH levels indicate decreased bone turnover. Recorded data could signify that vitamin D deficiency may contribute to the impaired bone metabolism of hemodialysis patients. (Clin. Lab. 2009;55:333-339)en
dc.publisherClin Lab Publ, Heidelberg
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/145010/RS//
dc.rightsrestrictedAccess
dc.sourceClinical Laboratory
dc.subjectVitamin Den
dc.subjectbone alkaline phosphataseen
dc.subjectbeta-CrossLapsen
dc.subjectparathyroid hormoneen
dc.subjecthemodialysisen
dc.subjectbone metabolismen
dc.titleRelation Between 25(OH)-Vitamin D Deficiency and Markers of Bone Formation and Resorption in Haemodialysis Patientsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМајкић-Сингх, Нада; Пејановић, Светлана Д.; Белетић, Aнђело; Милинковић, Неда; Вујанић, Светлана Т.; Мирковић, Душко;
dc.citation.volume55
dc.citation.issue9-10
dc.citation.spage333
dc.citation.epage339
dc.citation.other55(9-10): 333-339
dc.citation.rankM23
dc.identifier.wos000273176900001
dc.identifier.pmid20099569
dc.identifier.scopus2-s2.0-75749088406
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_1189
dc.type.versionpublishedVersion


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