Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide
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In this study it was described synthesis of new C-21 esters of fluocinolone acetonide with alpha-alkoxyalcanoic and alpha-aryloxyalkanoic acids. Esterification with these branched oxyacids has to improve benefit-risk ratio. All synthesized compound were shown some topical anti-inflammatory activity.
Source:Joint Meeting on Medical Chemistry, 2009, 41-
- Medimond S R L, 40128 Bologna
- Supstance za farmaceutsku upotrebu: modeliranje, sinteza, fizičko-hemijske i biološke osobine, stepen čistoće i ispitivanje doziranih oblika (RS-142072)