Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide

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Authors
Marković, Bojan
Vladimirov, S.
Pitić, D.
Savić, Vladimir
Jaćević, Vesna
Dobrić, Silva
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Abstract
In this study it was described synthesis of new C-21 esters of fluocinolone acetonide with alpha-alkoxyalcanoic and alpha-aryloxyalkanoic acids. Esterification with these branched oxyacids has to improve benefit-risk ratio. All synthesized compound were shown some topical anti-inflammatory activity.
Source:
Joint Meeting on Medical Chemistry, 2009, 41-
Publisher:
  • Medimond S R L, 40128 Bologna
Projects:

WoS: 000292154800009

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http://farfar.pharmacy.bg.ac.rs/handle/123456789/1196
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Pharmacy