Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide
Abstract
In this study it was described synthesis of new C-21 esters of fluocinolone acetonide with alpha-alkoxyalcanoic and alpha-aryloxyalkanoic acids. Esterification with these branched oxyacids has to improve benefit-risk ratio. All synthesized compound were shown some topical anti-inflammatory activity.
Source:
Joint Meeting on Medical Chemistry, 2009, 41-Publisher:
- Medimond S R L, 40128 Bologna
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PharmacyTY - CONF AU - Marković, Bojan AU - Vladimirov, S. AU - Pitić, D. AU - Savić, Vladimir AU - Jaćević, Vesna AU - Dobrić, Silva PY - 2009 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1196 AB - In this study it was described synthesis of new C-21 esters of fluocinolone acetonide with alpha-alkoxyalcanoic and alpha-aryloxyalkanoic acids. Esterification with these branched oxyacids has to improve benefit-risk ratio. All synthesized compound were shown some topical anti-inflammatory activity. PB - Medimond S R L, 40128 Bologna C3 - Joint Meeting on Medical Chemistry T1 - Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide SP - 41 UR - https://hdl.handle.net/21.15107/rcub_farfar_1196 ER -
@conference{ author = "Marković, Bojan and Vladimirov, S. and Pitić, D. and Savić, Vladimir and Jaćević, Vesna and Dobrić, Silva", year = "2009", abstract = "In this study it was described synthesis of new C-21 esters of fluocinolone acetonide with alpha-alkoxyalcanoic and alpha-aryloxyalkanoic acids. Esterification with these branched oxyacids has to improve benefit-risk ratio. All synthesized compound were shown some topical anti-inflammatory activity.", publisher = "Medimond S R L, 40128 Bologna", journal = "Joint Meeting on Medical Chemistry", title = "Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide", pages = "41", url = "https://hdl.handle.net/21.15107/rcub_farfar_1196" }
Marković, B., Vladimirov, S., Pitić, D., Savić, V., Jaćević, V.,& Dobrić, S.. (2009). Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide. in Joint Meeting on Medical Chemistry Medimond S R L, 40128 Bologna., 41. https://hdl.handle.net/21.15107/rcub_farfar_1196
Marković B, Vladimirov S, Pitić D, Savić V, Jaćević V, Dobrić S. Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide. in Joint Meeting on Medical Chemistry. 2009;:41. https://hdl.handle.net/21.15107/rcub_farfar_1196 .
Marković, Bojan, Vladimirov, S., Pitić, D., Savić, Vladimir, Jaćević, Vesna, Dobrić, Silva, "Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide" in Joint Meeting on Medical Chemistry (2009):41, https://hdl.handle.net/21.15107/rcub_farfar_1196 .