The chromatographic behavior of three biocidal technical materials, rodenticide active ingredients brodifacoum, bromadiolone, and coumatetralyl, and impurities present in the technical material was investigated by both normal-phase (NP) and reversed-phase (RP) planar chromatography. The research was carried out using thin-layers of silica gel, alumina, cellulose, and C-18 silica. Several solvents on their own or in various combinations and proportions were used for separation. The optimum chromatographic systems for separation of the substances from each other and from their impurities were selected. Under reversed-phase chromatographic (RPC) conditions a linear correlation between R-M values and mobile phase composition was established. From results obtained, the lipophilicity R-M(o) and C-0 were determined. Possible separation mechanisms are discussed on the basis of the established retention behavior.
TY - JOUR
AU - Tosti, Tomislav
AU - Rakić, Gordana
AU - Natić, Maja
AU - Milojković-Opsenica, Dušanka
AU - Husinec, Suren
AU - Savić, Vladimir
AU - Tešić, Živoslav
PY - 2009
UR - http://farfar.pharmacy.bg.ac.rs/handle/123456789/1199
AB - The chromatographic behavior of three biocidal technical materials, rodenticide active ingredients brodifacoum, bromadiolone, and coumatetralyl, and impurities present in the technical material was investigated by both normal-phase (NP) and reversed-phase (RP) planar chromatography. The research was carried out using thin-layers of silica gel, alumina, cellulose, and C-18 silica. Several solvents on their own or in various combinations and proportions were used for separation. The optimum chromatographic systems for separation of the substances from each other and from their impurities were selected. Under reversed-phase chromatographic (RPC) conditions a linear correlation between R-M values and mobile phase composition was established. From results obtained, the lipophilicity R-M(o) and C-0 were determined. Possible separation mechanisms are discussed on the basis of the established retention behavior.
PB - Akademiai Kiado Zrt, Budapest
T2 - Journal of Planar Chromatography - Modern TLC
T1 - TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents
VL - 22
IS - 5
SP - 333
EP - 343
DO - 10.1556/JPC.22.2009.5.4
ER -
@article{
author = "Tosti, Tomislav and Rakić, Gordana and Natić, Maja and Milojković-Opsenica, Dušanka and Husinec, Suren and Savić, Vladimir and Tešić, Živoslav",
year = "2009",
url = "http://farfar.pharmacy.bg.ac.rs/handle/123456789/1199",
abstract = "The chromatographic behavior of three biocidal technical materials, rodenticide active ingredients brodifacoum, bromadiolone, and coumatetralyl, and impurities present in the technical material was investigated by both normal-phase (NP) and reversed-phase (RP) planar chromatography. The research was carried out using thin-layers of silica gel, alumina, cellulose, and C-18 silica. Several solvents on their own or in various combinations and proportions were used for separation. The optimum chromatographic systems for separation of the substances from each other and from their impurities were selected. Under reversed-phase chromatographic (RPC) conditions a linear correlation between R-M values and mobile phase composition was established. From results obtained, the lipophilicity R-M(o) and C-0 were determined. Possible separation mechanisms are discussed on the basis of the established retention behavior.",
publisher = "Akademiai Kiado Zrt, Budapest",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents",
volume = "22",
number = "5",
pages = "333-343",
doi = "10.1556/JPC.22.2009.5.4"
}
Tosti, T., Rakić, G., Natić, M., Milojković-Opsenica, D., Husinec, S., Savić, V.,& Tešić, Ž. (2009). TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents.
Journal of Planar Chromatography - Modern TLC
Akademiai Kiado Zrt, Budapest., 22(5), 333-343.
https://doi.org/10.1556/JPC.22.2009.5.4
Tosti T, Rakić G, Natić M, Milojković-Opsenica D, Husinec S, Savić V, Tešić Ž. TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents. Journal of Planar Chromatography - Modern TLC. 2009;22(5):333-343
Tosti Tomislav, Rakić Gordana, Natić Maja, Milojković-Opsenica Dušanka, Husinec Suren, Savić Vladimir, Tešić Živoslav, "TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents" Journal of Planar Chromatography - Modern TLC, 22, no. 5 (2009):333-343,
https://doi.org/10.1556/JPC.22.2009.5.4 .
