Third-order derivative UV spectrophotometry and densitometry for the simultaneous assay of acetylsalicylic acid and salicylic acid in tablet formulations
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Third-order derivative spectrophotometry is proposed for simultaneous determination of acetylsalicylic acid and free salicylic acid in sustained-release tablets, and compared with TLC-densitometry. Both methods were evaluated through selectivity, and accuracy tests. Results for acetylsalicylic acid and salicylic acid in aspirin sustained-release tablets showed good agreement.
Source:Farmaco, 1995, 50, 4, 285-288
- Societa Chimica Italiana