Show simple item record

dc.creatorMitić, Dragana
dc.creatorMilenković, Marina
dc.creatorMilosavljević, Slobodan
dc.creatorGođevac, Dejan
dc.creatorMiodragović, Zoran M.
dc.creatorAnđelković, Katarina
dc.creatorMiodragović, Djenana
dc.date.accessioned2019-09-02T11:17:23Z
dc.date.available2019-09-02T11:17:23Z
dc.date.issued2009
dc.identifier.issn0223-5234
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1222
dc.description.abstractIn this paper the first complexes of M2+ ions (M2+ = Zn2+, Cd2+ and Co2+) with N-benzyloxycarbonyl-S-phenylalaninato ligand (1-3) are described. The new complexes were characterized by means of elemental analysis, IR and UV-vis spectroscopy, molar conductivity measurements and H-1, C-13 and N-15 NMR spectroscopy (1D and 2D). The Co(II) complex adopts an octahedral geometry, and the Zn(II) and Cd(II) complexes adopt a tetrahedral one. For the first time, the antimicrobial activity of N-benzyloxycarbonyl-S-phenylalaninato ligand (N-Boc-S-phe) and the complexes 1-3 was investigated against Gram-positive: Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Bacillus subtilis and Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and two strains of the yeast Candida albicans. It was shown that the complexes were effective against most strains. The best activity was detected against the yeast C. albicans.en
dc.publisherElsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/142062/RS//
dc.rightsrestrictedAccess
dc.sourceEuropean Journal of Medicinal Chemistry
dc.subjectAntimicrobial activityen
dc.subjectCo(II), Zn(II), Cd(II) complexesen
dc.subjectN-Benzyloxycarbonyl-S-phenylalanineen
dc.subject2D NMRen
dc.titleSynthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanineen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractГођевац, Дејан; Миленковић, Марина; Aнделковић, Катарина; Миодраговић, Дјенана; Миодраговић, Зоран М.; Милосављевић, Слободан; Митић, Драгана;
dc.citation.volume44
dc.citation.issue4
dc.citation.spage1537
dc.citation.epage1544
dc.citation.other44(4): 1537-1544
dc.citation.rankM21
dc.identifier.wos000264920000018
dc.identifier.doi10.1016/j.ejmech.2008.07.017
dc.identifier.pmid18760509
dc.identifier.scopus2-s2.0-61549109905
dc.identifier.rcubconv_2136
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record