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Univerzitet u Beogradu, Farmaceutski fakultet
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Atherogenic dyslipidemia and oxidative stress: a new look

Samo za registrovane korisnike
2009
Autori
Rizzo, Manfredi
Kotur-Stevuljević, Jelena
Berneis, Kaspar
Spinas, Giatgen
Rini, Giovam Battista
Jelić-Ivanović, Zorana
Spasojević-Kalimanovska, Vesna
Vekić, Jelena
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentu
Apstrakt
Although results from in vitro studies and clinical trials demonstrate strong associations between oxidative stress and cardiovascular risk, to date still no convincing data are available to suggest that treatment with antioxidants might reduce vascular events. Oxidative modifications of low-density lipoproteins (LDL) represent an early stage of atherosclerosis, and small, dense LDL are more susceptible to oxidation than larger, more buoyant particles. Oxidized LDL are independent predictors of subclinical and clinical atherosclerosis. Recent studies suggested that novel therapeutic strategies may take into account the removal of such particles from circulation. Future research is required to explore the potential synergistic impact of markers of oxidative stress and atherogenic dyslipidemia, particularly small dense LDL, on cardiovascular risk. (Translational Research 2009; 153:217-223)
Izvor:
Transplant International, 2009, 153, 5, 217-223
Izdavač:
  • Elsevier Science Inc, New York
Projekti:
  • Ispitivanje biohemijskih i genetičkih faktora rizika kao uzročnika i markera ateroskleroze i drugih oboljenja: analitički i klinički aspekti (RS-145036)

DOI: 10.1016/j.trsl.2009.01.008

ISSN: 1931-5244

PubMed: 19375682

WoS: 000265756600002

Scopus: 2-s2.0-64349105661
[ Google Scholar ]
81
77
URI
http://farfar.pharmacy.bg.ac.rs/handle/123456789/1228
Kolekcije
  • Radovi istraživača / Researchers’ publications
Institucija
Pharmacy

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