Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies

2009
Authors
Tomić, AnaPetrović, Silvana

Drobac, Milica

Trajkovski, Bojana
Milenković, Marina

Božić, Dragana

Niketić, Marjan

Article (Published version)
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The methanol extracts of fruits and leaves of Athamanta turbith subsp. hungarica (Borbas) Tutin (Umbelliferae) and A. turbith subsp. haynaldii (Borbas & Uechtr.) Tutin were analyzed for their antimicrobial and antioxidant properties. Phenolic compounds (flavonoids and phenolic acids) of the extracts were examined using HPLC. All the extracts were characterized by the presence of caffeic acid derivates, luteolin and its glycosides, with luteolin 7-O-glucoside as one of the main compounds. Luteolin 7-O-rutinoside was detected only in A. turbith subsp. haynaldii extracts. Investigation of antimicrobial activity was performed against six bacteria and two fungal strains, using the agar diffusion technique and broth microdilution assay. The extracts of investigated A. turbith subspecies exerted similar antimicrobial activity, whereas the best activity was detected against Candida albicans. In order to investigate antioxidant properties, ferric ion reducing antioxidant power (FRAP), radical s...cavenging capacity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical (HO.), and the effect on lipid peroxidation (LP) were examined. All the examined extracts showed moderate antioxidant capacity, whereas the fruit extracts were more active than the extracts of leaves. Also, the extracts of A. turbith subsp. hungarica exerted higher antioxidant capacity than corresponding A. turbith subsp. haynaldii extracts. The relationship between estimated activity and chemical composition of the extracts is discussed.
Keywords:
Athamanta turbith subsp hungarica / Athamanta turbith subsp haynaldii / antimicrobial activity / antioxidant activity / phenolic compoundsSource:
Pharmaceutical Biology, 2009, 47, 4, 314-319Publisher:
- Taylor & Francis Ltd, Abingdon
Funding / projects:
- Ispitivanje lekovitog potencijala biljaka: morfološka, hemijska i farmakološka karakterizacija (RS-143012)
- Diversity of the flora and vegetation of the Central Balkans: Ecology, chorology, and conservation (RS-143015)
DOI: 10.1080/13880200902748452
ISSN: 1388-0209
WoS: 000266630800009
Scopus: 2-s2.0-77149155692
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PharmacyTY - JOUR AU - Tomić, Ana AU - Petrović, Silvana AU - Drobac, Milica AU - Trajkovski, Bojana AU - Milenković, Marina AU - Božić, Dragana AU - Niketić, Marjan PY - 2009 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1273 AB - The methanol extracts of fruits and leaves of Athamanta turbith subsp. hungarica (Borbas) Tutin (Umbelliferae) and A. turbith subsp. haynaldii (Borbas & Uechtr.) Tutin were analyzed for their antimicrobial and antioxidant properties. Phenolic compounds (flavonoids and phenolic acids) of the extracts were examined using HPLC. All the extracts were characterized by the presence of caffeic acid derivates, luteolin and its glycosides, with luteolin 7-O-glucoside as one of the main compounds. Luteolin 7-O-rutinoside was detected only in A. turbith subsp. haynaldii extracts. Investigation of antimicrobial activity was performed against six bacteria and two fungal strains, using the agar diffusion technique and broth microdilution assay. The extracts of investigated A. turbith subspecies exerted similar antimicrobial activity, whereas the best activity was detected against Candida albicans. In order to investigate antioxidant properties, ferric ion reducing antioxidant power (FRAP), radical scavenging capacity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical (HO.), and the effect on lipid peroxidation (LP) were examined. All the examined extracts showed moderate antioxidant capacity, whereas the fruit extracts were more active than the extracts of leaves. Also, the extracts of A. turbith subsp. hungarica exerted higher antioxidant capacity than corresponding A. turbith subsp. haynaldii extracts. The relationship between estimated activity and chemical composition of the extracts is discussed. PB - Taylor & Francis Ltd, Abingdon T2 - Pharmaceutical Biology T1 - Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies VL - 47 IS - 4 SP - 314 EP - 319 DO - 10.1080/13880200902748452 ER -
@article{ author = "Tomić, Ana and Petrović, Silvana and Drobac, Milica and Trajkovski, Bojana and Milenković, Marina and Božić, Dragana and Niketić, Marjan", year = "2009", abstract = "The methanol extracts of fruits and leaves of Athamanta turbith subsp. hungarica (Borbas) Tutin (Umbelliferae) and A. turbith subsp. haynaldii (Borbas & Uechtr.) Tutin were analyzed for their antimicrobial and antioxidant properties. Phenolic compounds (flavonoids and phenolic acids) of the extracts were examined using HPLC. All the extracts were characterized by the presence of caffeic acid derivates, luteolin and its glycosides, with luteolin 7-O-glucoside as one of the main compounds. Luteolin 7-O-rutinoside was detected only in A. turbith subsp. haynaldii extracts. Investigation of antimicrobial activity was performed against six bacteria and two fungal strains, using the agar diffusion technique and broth microdilution assay. The extracts of investigated A. turbith subspecies exerted similar antimicrobial activity, whereas the best activity was detected against Candida albicans. In order to investigate antioxidant properties, ferric ion reducing antioxidant power (FRAP), radical scavenging capacity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical (HO.), and the effect on lipid peroxidation (LP) were examined. All the examined extracts showed moderate antioxidant capacity, whereas the fruit extracts were more active than the extracts of leaves. Also, the extracts of A. turbith subsp. hungarica exerted higher antioxidant capacity than corresponding A. turbith subsp. haynaldii extracts. The relationship between estimated activity and chemical composition of the extracts is discussed.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Pharmaceutical Biology", title = "Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies", volume = "47", number = "4", pages = "314-319", doi = "10.1080/13880200902748452" }
Tomić, A., Petrović, S., Drobac, M., Trajkovski, B., Milenković, M., Božić, D.,& Niketić, M.. (2009). Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies. in Pharmaceutical Biology Taylor & Francis Ltd, Abingdon., 47(4), 314-319. https://doi.org/10.1080/13880200902748452
Tomić A, Petrović S, Drobac M, Trajkovski B, Milenković M, Božić D, Niketić M. Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies. in Pharmaceutical Biology. 2009;47(4):314-319. doi:10.1080/13880200902748452 .
Tomić, Ana, Petrović, Silvana, Drobac, Milica, Trajkovski, Bojana, Milenković, Marina, Božić, Dragana, Niketić, Marjan, "Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies" in Pharmaceutical Biology, 47, no. 4 (2009):314-319, https://doi.org/10.1080/13880200902748452 . .